Found: 15
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Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML.
- Published in:
- Science Translational Medicine, 2024, v. 16, n. 728, p. 1, doi. 10.1126/scitranslmed.ade2774
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- Publication type:
- Article
Intron retention is a hallmark and spliceosome represents a therapeutic vulnerability in aggressive prostate cancer.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15815-7
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- Publication type:
- Article
Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08150-5
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- Publication type:
- Article
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07620-0
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- Publication type:
- Article
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
- Published in:
- Nature Communications, 2017, v. 8, n. 5, p. 15522, doi. 10.1038/ncomms15522
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- Publication type:
- Article
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities.
- Published in:
- Nature Medicine, 2013, v. 19, n. 11, p. 1518, doi. 10.1038/nm.3328
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- Publication type:
- Article
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.
- Published in:
- Nature, 2011, v. 473, n. 7346, p. 230, doi. 10.1038/nature09999
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- Publication type:
- Article
Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway.
- Published in:
- Nature Medicine, 2010, v. 16, n. 12, p. 1429, doi. 10.1038/nm.2251
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- Publication type:
- Article
Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma.
- Published in:
- Science Translational Medicine, 2010, v. 2, n. 51, p. 1, doi. 10.1126/scitranslmed.3001599
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- Publication type:
- Article
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
- Published in:
- Nature, 2009, v. 459, n. 7249, p. 1000, doi. 10.1038/nature08020
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- Publication type:
- Article
Molecular pathogenesis of T-cell leukaemia and lymphoma.
- Published in:
- 2008
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- Publication type:
- journal article
Targeting the NF-κB signaling pathway in Notch1-induced T-cell leukemia.
- Published in:
- Nature Medicine, 2007, v. 13, n. 1, p. 70, doi. 10.1038/nm1524
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- Publication type:
- Article
Rap1b is required for normal platelet function and hemostasis in mice.
- Published in:
- 2005
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- Publication type:
- Correction notice
EVI1 induces myelodysplastic syndrome in mice.
- Published in:
- 2005
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- Publication type:
- Correction notice
EVI1 induces myelodysplastic syndrome in mice.
- Published in:
- 2004
- By:
- Publication type:
- journal article