Works by Bunse, Lukas

Results: 23

T cell receptor dynamic and transcriptional determinants of T cell expansion in glioma-infiltrating T cells.

Published in:

Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac140

By:

Lu, Kevin Hai-Ning;
Michel, Julius;
Kilian, Michael;
Aslan, Katrin;
Hao Qi;
Kehl, Niklas;
Jung, Stefanie;
Sanghvi, Khwab;
Lindner, Katharina;
Xin-Wen Zhang;
Green, Edward W.;
Poschke, Isabel;
Ratliff, Miriam;
Bunse, Theresa;
Sahm, Felix;
von Deimling, Andreas;
Wick, Wolfgang;
Platten, Michael;
Bunse, Lukas

Publication type:

Article

A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors.

Published in:

Cancers, 2021, v. 13, n. 2, p. 230, doi. 10.3390/cancers13020230

By:

Costa, Barbara;
Fletcher, Michael N. C.;
Boskovic, Pavle;
Ivanova, Ekaterina L.;
Eisemann, Tanja;
Lohr, Sabrina;
Bunse, Lukas;
Löwer, Martin;
Burchard, Stefanie;
Korshunov, Andrey;
Coltella, Nadia;
Cusimano, Melania;
Naldini, Luigi;
Liu, Hai-Kun;
Platten, Michael;
Radlwimmer, Bernhard;
Angel, Peter;
Peterziel, Heike

Publication type:

Article

Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway.

Published in:

Glia (0894-1491), 2015, v. 63, n. 1, p. 78, doi. 10.1002/glia.22734

By:

Ott, Martina;
Litzenburger, Ulrike M.;
Rauschenbach, Katharina J.;
Bunse, Lukas;
Ochs, Katharina;
Sahm, Felix;
Pusch, Stefan;
Opitz, Christiane A.;
Blaes, Jonas;
von Deimling, Andreas;
Wick, Wolfgang;
Platten, Michael

Publication type:

Article

INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas.

Published in:

Neurological Research & Practice, 2023, v. 5, n. 1, p. 1, doi. 10.1186/s42466-023-00282-4

By:

Grassl, Niklas;
Sahm, Katharina;
Süße, Heike;
Poschke, Isabel;
Bunse, Lukas;
Bunse, Theresa;
Boschert, Tamara;
Mildenberger, Iris;
Rupp, Anne-Kathleen;
Ewinger, Max Philipp;
Lanz, Lisa-Marie;
Denk, Monika;
Tabatabai, Ghazaleh;
Ronellenfitsch, Michael W.;
Herrlinger, Ulrich;
Glas, Martin;
Krex, Dietmar;
Vajkoczy, Peter;
Wick, Antje;
Harting, Inga

Publication type:

Article

AMPLIFY-NEOVAC: a randomized, 3-arm multicenter phase I trial to assess safety, tolerability and immunogenicity of IDH1-vac combined with an immune checkpoint inhibitor targeting programmed death-ligand 1 in isocitrate dehydrogenase 1 mutant gliomas.

Published in:

Neurological Research & Practice, 2022, v. 4, n. 1, p. 1, doi. 10.1186/s42466-022-00184-x

By:

Bunse, Lukas;
Rupp, Anne-Kathleen;
Poschke, Isabel;
Bunse, Theresa;
Lindner, Katharina;
Wick, Antje;
Blobner, Jens;
Misch, Martin;
Tabatabai, Ghazaleh;
Glas, Martin;
Schnell, Oliver;
Gempt, Jens;
Denk, Monika;
Reifenberger, Guido;
Bendszus, Martin;
Wuchter, Patrick;
Steinbach, Joachim P;
Wick, Wolfgang;
Platten, Michael

Publication type:

Article

Site-Specific Considerations on Engineered T Cells for Malignant Gliomas.

Published in:

Biomedicines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/biomedicines10071738

By:

Elmadany, Nirmeen;
Alhalabi, Obada T.;
Platten, Michael;
Bunse, Lukas

Publication type:

Article

NLGN4X TCR transgenic T cells to treat gliomas.

Published in:

Neuro-Oncology, 2024, v. 26, n. 2, p. 266, doi. 10.1093/neuonc/noad172

By:

Krämer, Christoper;
Kilian, Michael;
Chih, Yu-Chan;
Kourtesakis, Alexandros;
Hoffmann, Dirk C;
Boschert, Tamara;
Koopmann, Philipp;
Sanghvi, Khwab;
Roia, Alice De;
Jung, Stefanie;
Jähne, Kristine;
Day, Bryan;
Shultz, Lenny D;
Ratliff, Miriam;
Harbottle, Richard;
Green, Edward W;
Will, Rainer;
Wick, Wolfgang;
Platten, Michael;
Bunse, Lukas

Publication type:

Article

Dysfunctional dendritic cells limit antigen-specific T cell response in glioma.

Published in:

Neuro-Oncology, 2023, v. 25, n. 2, p. 263, doi. 10.1093/neuonc/noac138

By:

Friedrich, Mirco;
Hahn, Markus;
Michel, Julius;
Sankowski, Roman;
Kilian, Michael;
Kehl, Niklas;
Günter, Manina;
Bunse, Theresa;
Pusch, Stefan;
Deimling, Andreas von;
Wick, Wolfgang;
Autenrieth, Stella E;
Prinz, Marco;
Platten, Michael;
Bunse, Lukas

Publication type:

Article

How mutant isocitrate dehydrogenase orchestrates immune cells.

Published in:

Neuro-Oncology, 2022, v. 24, n. 2, p. 210, doi. 10.1093/neuonc/noab266

By:

Bunse, Lukas;
Platten, Michael

Publication type:

Article

ATIM-33. NOA-16: A FIRST-IN-MAN MULTICENTER PHASE I CLINICAL TRIAL OF THE GERMAN NEUROONCOLOGY WORKING GROUP EVALUATING A MUTATION-SPECIFIC PEPTIDE VACCINE TARGETING IDH1R132H IN PATIENTS WITH NEWLY DIAGNOSED MALIGNANT ASTROCYTOMAS.

Published in:

Neuro-Oncology, 2018, v. 20, p. vi8, doi. 10.1093/neuonc/noy148.028

By:

Platten, Michael;
Schilling, Daniela;
Bunse, Lukas;
Wick, Antje;
Bunse, Theresa;
Riehl, Dennis;
Green, Edward;
Sanghvi, Khwab;
Karapanagiotou-Schenkel, Irini;
Harting, Inga

Publication type:

Article

IMMU-54. THE ONCOMETABOLITE R-2-HYDROXYGLUTARATE SUPPRESSES THE INNATE IMMUNE MICROENVIRONMENT OF IDH1-MUTATED GLIOMAS VIA ARYL HYDROCARBON RECEPTOR SIGNALING.

Published in:

Neuro-Oncology, 2018, v. 20, p. vi133, doi. 10.1093/neuonc/noy148.557

By:

Friedrich, Mirco;
Bunse, Lukas;
Bunse, Theresa;
Green, Edward;
Kessler, Tobias;
Pusch, Stefan;
Carretero, Rafael;
Deimling, Andreas von;
Quintana, Francisco J;
Wick, Wolfgang

Publication type:

Article

A vaccine targeting mutant IDH1 induces antitumour immunity.

Published in:

Nature, 2014, v. 512, n. 7514, p. 324, doi. 10.1038/nature13387

By:

Schumacher, Theresa;
Bunse, Lukas;
Pusch, Stefan;
Sahm, Felix;
Wiestler, Benedikt;
Quandt, Jasmin;
Menn, Oliver;
Osswald, Matthias;
Oezen, Iris;
Ott, Martina;
Keil, Melanie;
Balß, Jörg;
Rauschenbach, Katharina;
Grabowska, Agnieszka K.;
Vogler, Isabel;
Diekmann, Jan;
Trautwein, Nico;
Eichmüller, Stefan B.;
Okun, Jürgen;
Stevanović, Stefan

Publication type:

Article

AMPLIFY-NEOVAC: a randomized, 3-arm multicenter phase I trial to assess safety, tolerability and immunogenicity of IDH1-vac combined with an immune checkpoint inhibitor targeting programmed death-ligand 1 in isocitrate dehydrogenase 1 mutant gliomas.

Published in:

Neurological Research & Practice, 2022, p. 1, doi. 10.1186/s42466-022-00184-x

By:

Bunse, Lukas;
Rupp, Anne-Kathleen;
Poschke, Isabel;
Bunse, Theresa;
Lindner, Katharina;
Wick, Antje;
Blobner, Jens;
Misch, Martin;
Tabatabai, Ghazaleh;
Glas, Martin;
Schnell, Oliver;
Gempt, Jens;
Denk, Monika;
Reifenberger, Guido;
Bendszus, Martin;
Wuchter, Patrick;
Steinbach, Joachim P;
Wick, Wolfgang;
Platten, Michael

Publication type:

Article

Can health impact assessment help tackle commercial determinants of health and support a wellbeing economy?

Published in:

Health Promotion International, 2024, v. 39, n. 6, p. 1, doi. 10.1093/heapro/daae135

By:

Douglas, Margaret J;
Foster, Catherine;
McDermott, Rosalind;
Bunse, Lukas;
Clemens, Timo;
Walker, Jodie;
Green, Liz

Publication type:

Article

In vivo nanoparticle-based T cell imaging can predict therapy response towards adoptive T cell therapy in experimental glioma.

Published in:

Theranostics, 2023, v. 13, n. 15, p. 5170, doi. 10.7150/thno.87248

By:

Hunger, Jessica;
Schregel, Katharina;
Boztepe, Berin;
Agardy, Dennis Alexander;
Turco, Verena;
Karimian-Jazi, Kianush;
Weidenfeld, Ina;
Streibel, Yannik;
Fischer, Manuel;
Sturm, Volker;
Santarella-Mellwig, Rachel;
Kilian, Michael;
Jähne, Kristine;
Sahm, Katharina;
Wick, Wolfgang;
Bunse, Lukas;
Heiland, Sabine;
Bunse, Theresa;
Bendszus, Martin;
Platten, Michael

Publication type:

Article

Patient-Derived Tumor Organoids for Guidance of Personalized Drug Therapies in Recurrent Glioblastoma.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 12, p. 6572, doi. 10.3390/ijms23126572

By:

Ratliff, Miriam;
Kim, Hichul;
Qi, Hao;
Kim, Minsung;
Ku, Bosung;
Azorin, Daniel Dominguez;
Hausmann, David;
Khajuria, Rajiv K.;
Patel, Areeba;
Maier, Elena;
Cousin, Loic;
Ogier, Arnaud;
Sahm, Felix;
Etminan, Nima;
Bunse, Lukas;
Winkler, Frank;
El-Khoury, Victoria;
Platten, Michael;
Kwon, Yong-Jun

Publication type:

Article

Common T-Cell-Receptor Motifs and Features in Patients with Cytomegalovirus (CMV)-Seronegative End-Stage Renal Disease Receiving a Peptide Vaccination against CMV.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1029, doi. 10.3390/ijms23031029

By:

Bunse, Lukas;
Sommerer, Claudia;
Tan, Chin Leng;
Korell, Felix;
Schmitt, Anita;
Hückelhoven-Krauss, Angela;
Neuber, Brigitte;
Mertens, Thomas;
Platten, Michael;
Green, Edward W.;
Zeier, Martin;
Schmitt, Michael

Publication type:

Article

Genetically Modified Cellular Therapies for Malignant Gliomas.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 12810, doi. 10.3390/ijms222312810

By:

Kilian, Michael;
Bunse, Theresa;
Wick, Wolfgang;
Platten, Michael;
Bunse, Lukas

Publication type:

Article

Concepts in glioma immunotherapy.

Published in:

Cancer Immunology, Immunotherapy, 2016, v. 65, n. 10, p. 1269, doi. 10.1007/s00262-016-1874-x

By:

Platten, Michael;
Bunse, Lukas;
Wick, Wolfgang;
Bunse, Theresa

Publication type:

Article

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14642-0

By:

Aslan, Katrin;
Turco, Verena;
Blobner, Jens;
Sonner, Jana K.;
Liuzzi, Anna Rita;
Núñez, Nicolás Gonzalo;
De Feo, Donatella;
Kickingereder, Philipp;
Fischer, Manuel;
Green, Ed;
Sadik, Ahmed;
Friedrich, Mirco;
Sanghvi, Khwab;
Kilian, Michael;
Cichon, Frederik;
Wolf, Lara;
Jähne, Kristine;
von Landenberg, Anna;
Bunse, Lukas;
Sahm, Felix

Publication type:

Article

Intrathecal activation of CD8<sup>+</sup> memory T cells in IgG4‐related disease of the brain parenchyma.

Published in:

EMBO Molecular Medicine, 2021, v. 13, n. 8, p. 1, doi. 10.15252/emmm.202113953

By:

Friedrich, Mirco;
Kehl, Niklas;
Engelke, Niko;
Kraus, Josephine;
Lindner, Katharina;
Münch, Philipp;
Mildenberger, Iris;
Groden, Christoph;
Gass, Achim;
Etminan, Nima;
Fatar, Marc;
von Deimling, Andreas;
Reuss, David;
Platten, Michael;
Bunse, Lukas

Publication type:

Article

Proximity ligation assay evaluates IDH1R132H presentation in gliomas.

Published in:

2015

By:

Bunse, Lukas;
Schumacher, Theresa;
Sahm, Felix;
Pusch, Stefan;
Oezen, Iris;
Rauschenbach, Katharina;
Gonzalez, Marina;
Solecki, Gergely;
Osswald, Matthias;
Capper, David;
Wiestler, Benedikt;
Winkler, Frank;
Herold-Mende, Christel;
von Deimling, Andreas;
Wick, Wolfgang;
Platten, Michael

Publication type:

journal article

Proximity ligation assay evaluates IDH1<sup>R132H</sup> presentation in gliomas.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 593, doi. 10.1172/JCI77780

By:

Bunse, Lukas;
Schumacher, Theresa;
Sahm, Felix;
Pusch, Stefan;
Oezen, Iris;
Rauschenbach, Katharina;
Gonzalez, Marina;
Solecki, Gergely;
Osswald, Matthias;
Capper, David;
Wiestler, Benedikt;
Winkler, Frank;
Herold-Mende, Christel;
von Deimling, Andreas;
Wick, Wolfgang;
Platten, Michael

Publication type:

Article