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A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35126-3
By:
- Hackstein, Carl-Philipp;
- Costigan, Dana;
- Drexhage, Linnea;
- Pearson, Claire;
- Bullers, Samuel;
- Ilott, Nicholas;
- Akther, Hossain Delowar;
- Gu, Yisu;
- FitzPatrick, Michael E. B.;
- Harrison, Oliver J.;
- Garner, Lucy C.;
- Mann, Elizabeth H.;
- Pandey, Sumeet;
- Friedrich, Matthias;
- Provine, Nicholas M.;
- Uhlig, Holm H.;
- Marchi, Emanuele;
- Powrie, Fiona;
- Klenerman, Paul;
- Thornton, Emily E.
Publication type:
Article
Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27038-5
By:
- Ryzhakov, Grigory;
- Almuttaqi, Hannah;
- Corbin, Alastair L.;
- Berthold, Dorothée L.;
- Khoyratty, Tariq;
- Eames, Hayley L.;
- Bullers, Samuel;
- Pearson, Claire;
- Ai, Zhichao;
- Zec, Kristina;
- Bonham, Sarah;
- Fischer, Roman;
- Jostins-Dean, Luke;
- Travis, Simon P. L.;
- Kessler, Benedikt M.;
- Udalova, Irina A.
Publication type:
Article
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06085-5
By:
- Ryzhakov, Grigory;
- West, Nathaniel R.;
- Franchini, Fanny;
- Clare, Simon;
- Ilott, Nicholas E.;
- Sansom, Stephen N.;
- Bullers, Samuel J.;
- Pearson, Claire;
- Costain, Alice;
- Vaughan-Jackson, Alun;
- Goettel, Jeremy A.;
- Ermann, Joerg;
- Horwitz, Bruce H.;
- Buti, Ludovico;
- Lu, Xin;
- Mukhopadhyay, Subhankar;
- Snapper, Scott B.;
- Powrie, Fiona
Publication type:
Article
Tumour-associated changes in intestinal epithelial cells cause local accumulation of KLRG1<sup>+</sup> GATA3<sup>+</sup> regulatory T cells in mice.
Published in:
Immunology, 2017, v. 152, n. 1, p. 74, doi. 10.1111/imm.12750
By:
- Meinicke, Holger;
- Bremser, Anna;
- Brack, Maria;
- Akeus, Paulina;
- Pearson, Claire;
- Bullers, Samuel;
- Hoffmeyer, Katrin;
- Stemmler, Marc P.;
- Quiding‐Järbrink, Marianne;
- Izcue, Ana
Publication type:
Article
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.
Published in:
Science Translational Medicine, 2023, v. 15, n. 706, p. 1, doi. 10.1126/scitranslmed.abn4722
By:
- Thompson, Kelsey N.;
- Bonham, Kevin S.;
- Ilott, Nicholas E.;
- Britton, Graham J.;
- Colmenero, Paula;
- Bullers, Samuel J.;
- McIver, Lauren J.;
- Ma, Siyuan;
- Nguyen, Long H.;
- Filer, Andrew;
- Brough, India;
- Pearson, Claire;
- Moussa, Caroline;
- Kumar, Vinod;
- Lam, Lilian H.;
- Jackson, Matthew A.;
- Pawluk, April;
- Kiriakidis, Serafim;
- Taylor, Peter C.;
- Wedderburn, Lucy R.
Publication type:
Article

Found: 5

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.

Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.

Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.

Tumour-associated changes in intestinal epithelial cells cause local accumulation of KLRG1<sup>+</sup> GATA3<sup>+</sup> regulatory T cells in mice.

Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.