Works by Buffenstein, Rochelle

Results: 59

From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span.

Published in:

Annals of the New York Academy of Sciences, 2016, v. 1363, n. 1, p. 155, doi. 10.1111/nyas.13032

By:

McIsaac, R. Scott;
Lewis, Kaitlyn N.;
Gibney, Patrick A.;
Buffenstein, Rochelle

Publication type:

Article

Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2008, v. 178, n. 4, p. 439, doi. 10.1007/s00360-007-0237-5

By:

Buffenstein, Rochelle

Publication type:

Article

Establishment of primary and immortalized fibroblasts reveals resistance to cytotoxic agents and loss of necroptosis-inducing ability in long-lived Damaraland mole-rats.

Published in:

GeroScience, 2025, v. 47, n. 1, p. 1381, doi. 10.1007/s11357-024-01420-9

By:

Suzuki, Yusuke;
Yamaguchi, Kanta;
Hardell, Kaitlyn N. Lewis;
Ota, Kurumi;
Kamikado, Taira;
Kawamura, Yoshimi;
Buffenstein, Rochelle;
Oka, Kaori;
Miura, Kyoko

Publication type:

Article

Five years later, with double the demographic data, naked mole-rat mortality rates continue to defy Gompertzian laws by not increasing with age.

Published in:

GeroScience, 2024, v. 46, n. 5, p. 5321, doi. 10.1007/s11357-024-01201-4

By:

Ruby, J. Graham;
Smith, Megan;
Buffenstein, Rochelle

Publication type:

Article

Naked mole-rats maintain cardiac function and body composition well into their fourth decade of life.

Published in:

GeroScience, 2022, v. 44, n. 2, p. 731, doi. 10.1007/s11357-022-00522-6

By:

Can, Emine;
Smith, Megan;
Boukens, Bastiaan J.;
Coronel, Ruben;
Buffenstein, Rochelle;
Riegler, Johannes

Publication type:

Article

Correction to: A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence.

Published in:

GeroScience, 2018, v. 40, n. 3, p. 357, doi. 10.1007/s11357-018-0023-1

By:

Lewis, Kaitlyn N.;
Rubinstein, Nimrod D.;
Buffenstein, Rochelle

Publication type:

Article

A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence.

Published in:

GeroScience, 2018, v. 40, n. 2, p. 105, doi. 10.1007/s11357-018-0014-2

By:

Lewis, Kaitlyn N.;
Rubinstein, Nimrod D.;
Buffenstein, Rochelle

Publication type:

Article

Gene expression defines natural changes in mammalian lifespan.

Published in:

Aging Cell, 2015, v. 14, n. 3, p. 352, doi. 10.1111/acel.12283

By:

Fushan, Alexey A.;
Turanov, Anton A.;
Lee, Sang‐Goo;
Kim, Eun Bae;
Lobanov, Alexei V.;
Yim, Sun Hee;
Buffenstein, Rochelle;
Lee, Sang‐Rae;
Chang, Kyu‐Tae;
Rhee, Hwanseok;
Kim, Jong‐So;
Yang, Kap‐Seok;
Gladyshev, Vadim N.

Publication type:

Article

Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity.

Published in:

Aging Cell, 2012, v. 11, n. 2, p. 213, doi. 10.1111/j.1474-9726.2011.00772.x

By:

Edrey, Yael H.;
Casper, Diana;
Huchon, Dorothee;
Mele, James;
Gelfond, Jonathan A.;
Kristan, Deborah M.;
Nevo, Eviatar;
Buffenstein, Rochelle

Publication type:

Article

Attenuation of liver insoluble protein carbonyls: indicator of a longevity determinant?

Published in:

Aging Cell, 2011, v. 10, n. 4, p. 720, doi. 10.1111/j.1474-9726.2011.00712.x

By:

Bhattacharya, Arunabh;
Leonard, Shanique;
Tardif, Suzette;
Buffenstein, Rochelle;
Fischer, Kathleen E.;
Richardson, Arlan;
Austad, Steven N.;
Chaudhuri, Asish R.

Publication type:

Article

Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat ( Heterocephalus glaber).

Published in:

Aging Cell, 2010, v. 9, n. 4, p. 626, doi. 10.1111/j.1474-9726.2010.00588.x

By:

Liang, Sitai;
Mele, James;
Wu, Yuehong;
Buffenstein, Rochelle;
Hornsby, Peter J.

Publication type:

Article

Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms.

Published in:

Aging Cell, 2007, v. 6, n. 5, p. 607, doi. 10.1111/j.1474-9726.2007.00312.x

By:

Lambert, Adrian J.;
Boysen, Helen M.;
Buckingham, Julie A.;
Ting Yang;
Podlutsky, Andrej;
Austad, Steven N.;
Kunz, Thomas H.;
Buffenstein, Rochelle;
Brand, Martin D.

Publication type:

Article

High oxidative damage levels in the longest-living rodent, the naked mole-rat.

Published in:

Aging Cell, 2006, v. 5, n. 6, p. 463, doi. 10.1111/j.1474-9726.2006.00237.x

By:

Andziak, Blazej;
O'Connor, Timothy P.;
Qi, Wenbo;
DeWaal, Eric M.;
Pierce, Anson;
Chaudhuri, Asish R.;
Van Remmen, Holly;
Buffenstein, Rochelle

Publication type:

Article

Disparate patterns of age-related changes in lipid peroxidation in long-lived naked mole-rats and shorter-lived mice.

Published in:

Aging Cell, 2006, v. 5, n. 6, p. 525, doi. 10.1111/j.1474-9726.2006.00246.x

By:

Andziak, Blazej;
Buffenstein, Rochelle

Publication type:

Article

Evolution of T cells in the cancer-resistant naked mole-rat.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47264-x

By:

Lin, Tzuhua D.;
Rubinstein, Nimrod D.;
Fong, Nicole L.;
Smith, Megan;
Craft, Wendy;
Martin-McNulty, Baby;
Perry, Rebecca;
Delaney, Martha A.;
Roy, Margaret A.;
Buffenstein, Rochelle

Publication type:

Article

Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.

Published in:

Neurochemical Research, 2016, v. 41, n. 7, p. 1625, doi. 10.1007/s11064-016-1877-1

By:

Triplett, Judy;
Swomley, Aaron;
Kirk, Jessime;
Grimes, Kelly;
Lewis, Kaitilyn;
Orr, Miranda;
Rodriguez, Karl;
Cai, Jian;
Klein, Jon;
Buffenstein, Rochelle;
Butterfield, D.

Publication type:

Article

The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms.

Published in:

Age (0161-9152), 2008, v. 30, n. 2/3, p. 99, doi. 10.1007/s11357-008-9058-z

By:

Buffenstein, Rochelle;
Edrey, YaeI H.;
Ting Yang;
Mele, James

Publication type:

Article

The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole‐rat biology.

Published in:

2022

By:

Buffenstein, Rochelle;
Amoroso, Vincent;
Andziak, Blazej;
Avdieiev, Stanislav;
Azpurua, Jorge;
Barker, Alison J.;
Bennett, Nigel C.;
Brieño‐Enríquez, Miguel A.;
Bronner, Gary N.;
Coen, Clive;
Delaney, Martha A.;
Dengler‐Crish, Christine M.;
Edrey, Yael H.;
Faulkes, Chris G.;
Frankel, Daniel;
Friedlander, Gerard;
Gibney, Patrick A.;
Gorbunova, Vera;
Hine, Christopher;
Holmes, Melissa M.

Publication type:

Literature Review

Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity.

Published in:

PLoS Biology, 2019, v. 17, n. 11, p. 1, doi. 10.1371/journal.pbio.3000528

By:

Hilton, Hugo G.;
Rubinstein, Nimrod D.;
Janki, Peter;
Ireland, Andrea T.;
Bernstein, Nicholas;
Fong, Nicole L.;
Wright, Kevin M.;
Smith, Megan;
Finkle, David;
Martin-McNulty, Baby;
Roy, Margaret;
Imai, Denise M.;
Jojic, Vladimir;
Buffenstein, Rochelle

Publication type:

Article

Getting to the Heart of the Matter: Age-related Changes in Diastolic Heart Function in the Longest-lived Rodent, the Naked Mole Rat.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67A, n. 4, p. 384, doi. 10.1093/gerona/glr222

By:

Grimes, Kelly M.;
Lindsey, Merry L.;
Gelfond, Jonathan A. L.;
Buffenstein, Rochelle

Publication type:

Article

Fibroblasts From Naked Mole-Rats Are Resistant to Multiple Forms of Cell Injury, But Sensitive to Peroxide, Ultraviolet Light, and Endoplasmic Reticulum Stress.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2008, v. 63, n. 3, p. 232, doi. 10.1093/gerona/63.3.232

By:

Salmon, Adam B.;
Sadighi Akha, Amir A.;
Buffenstein, Rochelle;
Miller, Richard A.

Publication type:

Article

Oxidation-Resistant Membrane Phospholipids Can Explain Longevity Differences Among the Longest-Living Rodents and Similarly-Sized Mice.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2006, v. 61, n. 10, p. 1009, doi. 10.1093/gerona/61.10.1009

By:

Hulbert, A. J.;
Faulks, Sally C.;
Buffenstein, Rochelle

Publication type:

Article

The naked mole-rat: a new long-living model for human aging research.

Published in:

2005

By:

Buffenstein, Rochelle

Publication type:

journal article

Stress Resistance in the Naked Mole-Rat: The Bare Essentials - A Mini-Review.

Published in:

Gerontology, 2012, v. 58, n. 5, p. 453, doi. 10.1159/000335966

By:

Lewis, Kaitlyn N.;
Mele, James;
Hornsby, Peter J.;
Buffenstein, Rochelle

Publication type:

Article

Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00083

By:

Rodriguez, Karl A.;
Dodds, Sherry G.;
Strong, Randy;
Galvan, Veronica;
Sharp, Z. D.;
Buffenstein, Rochelle

Publication type:

Article

Glucose tolerance and insulin sensitivity in an extremely long-living rodent, the naked mole-rat.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1423, doi. 10.1096/fasebj.21.6.a1423-c

By:

Buffenstein, Rochelle;
Kang, Joy;
Biney, Adriana

Publication type:

Article

Expression of Heregulin may be associated with rodent longevity: a comparative approach.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1401, doi. 10.1096/fasebj.21.6.a1401-d

By:

Edrey, Yael H.;
Buffenstein, Rochelle;
Pidel, Ann;
Casper, Diana

Publication type:

Article

Comparison of endothelial function, O2.- and H2O2 production and vascular oxidative stress resistance between the longest-living rodent, the naked mole-rat and mice.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1237, doi. 10.1096/fasebj.21.6.a1237-b

By:

Labinskyy, Nazar;
Csiszar, Anna;
Orosz, Zsuzsanna;
Rivera, Aracelie;
Smith, Kira;
Buffenstein, Rochelle;
Ungvari, Zoltan

Publication type:

Article

Vascular aging in the longest-living rodent, the naked mole-rat.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A851, doi. 10.1096/fasebj.21.6.a851-c

By:

Csiszar, Anna;
Labinskyy, Nazar;
Orosz, Zsuzsanna;
Buffenstein, Rochelle;
Ungvari, Zoltan

Publication type:

Article

Rodent Longevity is not Directly Associated with Glutathione Cycle.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A821

By:

Ting Yang;
Andziak, Blazej;
Buffenstein, Rochelle

Publication type:

Article

The Fourth Annual Symposium of the Midwest Aging Consortium.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 11, p. 1, doi. 10.1093/gerona/glae236

By:

Kim, Jinoh;
Buffenstein, Rochelle;
Bronikowski, Anne M;
Vanegas, Natalia-Del Pilar;
Rosas, Lorena;
Agudelo-Garcia, Paula;
Mora, Ana L;
Rojas, Mauricio;
Englund, Davis A;
LeBrasseur, Nathan K;
Nunes, Allancer;
Robbins, Paul D;
Kohut, Marian L;
Kothadiya, Siddhant;
Bardhan, Rizia;
Camell, Christina D;
Sturmlechner, Ines;
Goronzy, Jörg J;
Yeh, Chung-Yang;
Lamming, Dudley W

Publication type:

Article

The Untapped Potential of Comparative Biology in Aging Research: Insights From the Extraordinary-Long-Lived Naked Mole-Rat.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 8, p. 1, doi. 10.1093/gerona/glae110

By:

Buffenstein, Rochelle;
Amoroso, Vince G

Publication type:

Article

The First International Mini-Symposium on Methionine Restriction and Lifespan.

Published in:

Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00122

By:

Abies, Gene P.;
Brown-Borg, Holly M.;
Buffenstein, Rochelle;
Church, Christopher D.;
Elshorbagy, Amany K.;
Gladyshev, Vadim N.;
Tsang-hai Huang;
Miller, Richard A.;
Mitchell, James R.;
Richie, John P.;
Rogina, Blanka;
Stipanuk, Martha H.;
Orentreich, David S.;
Orentreich, Norman

Publication type:

Article

Comparative Studies of Oxidative Stress and Mitochondrial Function in Aging.

Published in:

Integrative & Comparative Biology, 2010, v. 50, n. 5, p. 869, doi. 10.1093/icb/icq079

By:

Yun Shi;
Buffenstein, Rochelle;
Pulliam, Daniel A.;
Van Remmen, Holly

Publication type:

Article

Nrf2, a Guardian of Healthspan and Gatekeeper of Species Longevity.

Published in:

Integrative & Comparative Biology, 2010, v. 50, n. 5, p. 829, doi. 10.1093/icb/icq034

By:

Lewis, Kaitlyn N.;
Mele, James;
Hayes, John D.;
Buffenstein, Rochelle

Publication type:

Article

Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents.

Published in:

Journal of Neuroscience Research, 2014, v. 92, n. 2, p. 195, doi. 10.1002/jnr.23320

By:

Edrey, Yael H.;
Oddo, Salvatore;
Cornelius, Carolin;
Caccamo, Antonella;
Calabrese, Vittorio;
Buffenstein, Rochelle

Publication type:

Article

Homology cluster differential expression analysis for interspecies mRNA-Seq experiments.

Published in:

Statistical Applications in Genetics & Molecular Biology, 2015, v. 14, n. 6, p. 507, doi. 10.1515/sagmb-2014-0056

By:

Gelfond, Jonathan A.;
Ibrahim, Joseph G.;
Chen, Ming-Hui;
Sun, Wei;
Lewis, Kaitlyn;
Kinahan, Sean;
Hibbs, Matthew;
Buffenstein, Rochelle

Publication type:

Article

Seasonal and daily variation in blood and urine concentrations of free-ranging Angolan free-tailed bats (Mops condylurus) in hot roosts in southern Africa.

Published in:

South African Journal of Zoology, 1999, v. 34, n. 1, p. 11, doi. 10.1080/02541858.1999.11448482

By:

Buffenstein, Rochelle;
Maloney, Shane K.;
Brenner, Gary N.

Publication type:

Article

Survival tactics within thermally-challenging roosts: heat tolerance and cold sensitivity in the Angolan free-tailed bat, Mops condylurus.

Published in:

South African Journal of Zoology, 1999, v. 34, n. 1, p. 1, doi. 10.1080/02541858.1999.11448481

By:

Bronner, Gary N.;
Maloney, Shane K.;
Buffenstein, Rochelle

Publication type:

Article

The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent.

Published in:

Pflügers Archiv: European Journal of Physiology, 2017, v. 469, n. 12, p. 1603, doi. 10.1007/s00424-017-2046-3

By:

Grimes, Kelly;
Barefield, David;
Kumar, Mohit;
McNamara, James;
Weintraub, Susan;
Tombe, Pieter;
Sadayappan, Sakthivel;
Buffenstein, Rochelle

Publication type:

Article

Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64009-0

By:

Deuker, Marian M.;
Lewis, Kaitlyn N.;
Ingaramo, Maria;
Kimmel, Jacob;
Buffenstein, Rochelle;
Settleman, Jeff

Publication type:

Article

Skin morphology and its role in thermoregulation in mole-rats, Heterocephalus glaber and Cryptomys hottentotus.

Published in:

Journal of Anatomy, 1998, v. 193, n. 4, p. 495, doi. 10.1046/j.1469-7580.1998.19340495.x

By:

DALY, T. JOSEPH M.;
BUFFENSTEIN, ROCHELLE

Publication type:

Article

Catecholaminergic innervation of interscapular brown adipose tissue in the naked mole-rat ( Heterocephalus glaber).

Published in:

Journal of Anatomy, 1997, v. 190, n. 3, p. 321, doi. 10.1046/j.1469-7580.1997.19030321.x

By:

DALY, T. JOSEPH M.;
WILLIAMS, LAURA A.;
BUFFENSTEIN, ROCHELLE

Publication type:

Article

Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.

Published in:

Journal of Neurochemistry, 2015, v. 134, n. 3, p. 538, doi. 10.1111/jnc.13149

By:

Triplett, Judy C.;
Swomley, Aaron;
Kirk, Jessime;
Lewis, Katilyn;
Orr, Miranda;
Rodriguez, Karl;
Cai, Jian;
Klein, Jon B.;
Buffenstein, Rochelle;
Butterfield, D. Allan

Publication type:

Article

Elevated Protein Carbonylation, and Misfolding in Sciatic Nerve from db/db and Sod1−/− Mice: Plausible Link between Oxidative Stress and Demyelination.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065725

By:

Hamilton, Ryan T.;
Bhattacharya, Arunabh;
Walsh, Michael E.;
Shi, Yun;
Wei, Rochelle;
Zhang, Yiqiang;
Rodriguez, Karl A.;
Buffenstein, Rochelle;
Chaudhuri, Asish R.;
Van Remmen, Holly

Publication type:

Article

Altered Composition of Liver Proteasome Assemblies Contributes to Enhanced Proteasome Activity in the Exceptionally Long-Lived Naked Mole-Rat.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0035890

By:

Rodriguez, Karl A.;
Edrey, Yael H.;
Osmulski, Pawel;
Gaczynska, Maria;
Buffenstein, Rochelle

Publication type:

Article

Blunted Neuronal Calcium Response to Hypoxia in Naked Mole-Rat Hippocampus.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031568

By:

Peterson, Bethany L.;
Larson, John;
Buffenstein, Rochelle;
Park, Thomas J.;
Fall, Christopher P.

Publication type:

Article

RNA Sequencing Reveals Differential Expression of Mitochondrial and Oxidation Reduction Genes in the Long-Lived Naked Mole-Rat When Compared to Mice.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0026729

By:

Chuanfei Yu;
Yang Li;
Holmes, Andrew;
Szafranski, Karol;
Faulkes, Chris G.;
Coen, Clive W.;
Buffenstein, Rochelle;
Platzer, Matthias;
Magalhães, João Pedro de;
Church, George M.

Publication type:

Article

Extended Postnatal Brain Development in the Longest-Lived Rodent: Prolonged Maintenance of Neotenous Traits in the Naked Mole-Rat Brain.

Published in:

Frontiers in Neuroscience, 2016, v. 10, p. 1, doi. 10.3389/fnins.2016.00504

By:

Orr, Miranda E.;
Garbarino, Valentina R.;
Salinas, Angelica;
Buffenstein, Rochelle;
Sallet, Jérôme;
Cozzi, Bruno

Publication type:

Article

Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.31157

By:

Ruby, J. Graham;
Smith, Megan;
Buffenstein, Rochelle

Publication type:

Article