Works by Bucher, Simon

Results: 11

Single-nuclei characterization of pervasive transcriptional signatures across organs in response to COVID-19.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.81090

By:

Granados, Alejandro A.;
Bucher, Simon;
Hanbing Song;
Agrawal, Aditi;
Chen, Ann T.;
Tien Peng;
Neff, Norma;
Oliveira Pisco, Angela;
Huang, Franklin;
Wang, Bruce

Publication type:

Article

Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes.

Published in:

Archives of Toxicology, 2018, v. 92, n. 10, p. 3077, doi. 10.1007/s00204-018-2300-2

By:

Quesnot, Nicolas;
Bucher, Simon;
Gade, Christina;
Vlach, Manuel;
Vene, Elise;
Valença, Samuel;
Gicquel, Thomas;
Holst, Helle;
Robin, Marie-Anne;
Loyer, Pascal

Publication type:

Article

Moderate chronic ethanol consumption exerts beneficial effects on nonalcoholic fatty liver in mice fed a high-fat diet: possible role of higher formation of triglycerides enriched in monounsaturated fatty acids.

Published in:

European Journal of Nutrition, 2020, v. 59, n. 4, p. 1619, doi. 10.1007/s00394-019-02017-1

By:

Bucher, Simon;
Begriche, Karima;
Catheline, Daniel;
Trak-Smayra, Viviane;
Tiaho, François;
Coulouarn, Cédric;
Pinon, Grégory;
Lagadic-Gossmann, Dominique;
Rioux, Vincent;
Fromenty, Bernard

Publication type:

Article

Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure.

Published in:

Environmental Toxicology, 2017, v. 32, n. 3, p. 1024, doi. 10.1002/tox.22301

By:

Bucher, Simon;
Jalili, Pégah;
Le Guillou, Dounia;
Begriche, Karima;
Rondel, Karine;
Martinais, Sophie;
Zalko, Daniel;
Corlu, Anne;
Robin, Marie‐Anne;
Fromenty, Bernard

Publication type:

Article

Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure.

Published in:

Cell Biology & Toxicology, 2023, v. 39, n. 2, p. 371, doi. 10.1007/s10565-022-09706-4

By:

Imran, Muhammad;
Chalmel, Frédéric;
Sergent, Odile;
Evrard, Bertrand;
Le Mentec, Hélène;
Legrand, Antoine;
Dupont, Aurélien;
Bescher, Maëlle;
Bucher, Simon;
Fromenty, Bernard;
Huc, Laurence;
Sparfel, Lydie;
Lagadic-Gossmann, Dominique;
Podechard, Normand

Publication type:

Article

Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity.

Published in:

Cell Biology & Toxicology, 2021, v. 37, n. 2, p. 151, doi. 10.1007/s10565-020-09537-1

By:

Allard, Julien;
Bucher, Simon;
Massart, Julie;
Ferron, Pierre-Jean;
Le Guillou, Dounia;
Loyant, Roxane;
Daniel, Yoann;
Launay, Youenn;
Buron, Nelly;
Begriche, Karima;
Borgne-Sanchez, Annie;
Fromenty, Bernard

Publication type:

Article

Regulation of Hepatic Drug Transporter Activity and Expression by Organochlorine Pesticides.

Published in:

Journal of Biochemical & Molecular Toxicology, 2014, v. 28, n. 3, p. 119, doi. 10.1002/jbt.21543

By:

Bucher, Simon;
Le Vee, Marc;
Jouan, Elodie;
Fardel, Olivier

Publication type:

Article

Busulfan induces steatosis in HepaRG cells but not in primary human hepatocytes: Possible explanations and implication for the prediction of drug‐induced liver injury.

Published in:

Fundamental & Clinical Pharmacology, 2024, v. 38, n. 1, p. 152, doi. 10.1111/fcp.12951

By:

Allard, Julien;
Bucher, Simon;
Ferron, Pierre‐Jean;
Launay, Youenn;
Fromenty, Bernard

Publication type:

Article

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.

Published in:

Oxidative Medicine & Cellular Longevity, 2018, p. 1, doi. 10.1155/2018/4396403

By:

Bucher, Simon;
Le Guillou, Dounia;
Allard, Julien;
Pinon, Grégory;
Begriche, Karima;
Tête, Arnaud;
Sergent, Odile;
Lagadic-Gossmann, Dominique;
Fromenty, Bernard

Publication type:

Article

Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32473-z

By:

Song, Hanbing;
Bucher, Simon;
Rosenberg, Katherine;
Tsui, Margaret;
Burhan, Deviana;
Hoffman, Daniel;
Cho, Soo-Jin;
Rangaswami, Arun;
Breese, Marcus;
Leung, Stanley;
Ventura, María V. Pons;
Sweet-Cordero, E. Alejandro;
Huang, Franklin W.;
Nijagal, Amar;
Wang, Bruce

Publication type:

Article

Polycyclic Aromatic Hydrocarbons Can Trigger Hepatocyte Release of Extracellular Vesicles by Various Mechanisms of Action Depending on Their Affinity for the Aryl Hydrocarbon Receptor.

Published in:

Toxicological Sciences, 2019, v. 171, n. 2, p. 443, doi. 10.1093/toxsci/kfz157

By:

Meteren, Nettie van;
Lagadic-Gossmann, Dominique;
Chevanne, Martine;
Gallais, Isabelle;
Gobart, Dimitri;
Burel, Agnès;
Bucher, Simon;
Grova, Nathalie;
Fromenty, Bernard;
Appenzeller, Brice M R;
Chevance, Soizic;
Gauffre, Fabienne;
Ferrec, Eric Le;
Sergent, Odile

Publication type:

Article