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Semisynthetic and Enzyme‐Mediated Conjugate Preparations Illuminate the Ubiquitination‐Dependent Aggregation of Tau Protein.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 16, p. 6669, doi. 10.1002/ange.201916756
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- Publication type:
- Article
COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside.
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- NPJ Parkinson's Disease, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41531-020-00123-0
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- Publication type:
- Article
Sequestosome-1 (SQSTM1/p62) as a target in dopamine catabolite-mediated cellular dyshomeostasis.
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- Cell Death & Disease, 2024, v. 15, n. 6, p. 1, doi. 10.1038/s41419-024-06763-x
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- Publication type:
- Article
Single-Molecule-Level Evidence for the Osmophobic Effect.
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- Angewandte Chemie International Edition, 2011, v. 50, n. 19, p. 4394, doi. 10.1002/anie.201006714
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- Publication type:
- Article
NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells.
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- FASEB Journal, 2015, v. 29, n. 6, p. 2484, doi. 10.1096/fj.14-260281
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- Publication type:
- Article
Dysfunction of dopamine homeostasis: clues in the hunt for novel Parkinson's disease therapies.
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- FASEB Journal, 2013, v. 27, n. 6, p. 2101, doi. 10.1096/fj.12-226852
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- Publication type:
- Article
Structural insights on physiological functions and pathological effects of α-synuclein.
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- FASEB Journal, 2009, v. 23, n. 2, p. 329, doi. 10.1096/fj.08-119784
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- Publication type:
- Article
Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain.
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- Journal of Neurochemistry, 2015, v. 135, n. 6, p. 1242, doi. 10.1111/jnc.13369
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- Article
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease.
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- Journal of Neurochemistry, 2005, v. 93, n. 1, p. 246, doi. 10.1111/j.1471-4159.2005.03019.x
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- Article
Erratum to: Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells.
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- 2016
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- Publication type:
- corrected article
Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells.
- Published in:
- 2015
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- Publication type:
- journal article
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
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- Journal of Neuroinflammation, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1742-2094-11-52
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- Publication type:
- Article
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
- Published in:
- 2014
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- Publication type:
- journal article
Unsymmetrical Binding Modes of the HOPNO Inhibitor of Tyrosinase: From Model Complexes to the Enzyme.
- Published in:
- Chemistry - A European Journal, 2013, v. 19, n. 11, p. 3655, doi. 10.1002/chem.201202643
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- Publication type:
- Article
Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau.
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- Molecules, 2020, v. 25, n. 11, p. 2716, doi. 10.3390/molecules25112716
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- Publication type:
- Article
The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity.
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- Human Molecular Genetics, 2014, v. 23, n. 21, p. 5615, doi. 10.1093/hmg/ddu275
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- Publication type:
- Article
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2.
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- Human Molecular Genetics, 2013, v. 22, n. 6, p. 1140, doi. 10.1093/hmg/dds522
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- Publication type:
- Article
Cross-talk between LRRK2 and PKA: implication for Parkinson's disease?
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- Biochemical Society Transactions, 2017, v. 45, n. 1, p. 261, doi. 10.1042/BST20160396
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- Publication type:
- Article
Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions?
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- Biochemical Society Transactions, 2012, v. 40, n. 5, p. 1095, doi. 10.1042/BST20120123
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- Publication type:
- Article
Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity.
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- Quarterly Reviews of Biophysics, 2014, v. 47, n. 1, p. 1, doi. 10.1017/S0033583513000097
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- Publication type:
- Article
Neuroprotective Effect of Antiapoptotic URG7 Protein on Human Neuroblastoma Cell Line SH-SY5Y.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 481, doi. 10.3390/ijms25010481
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- Article
Metformin Repurposing for Parkinson Disease Therapy: Opportunities and Challenges.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 398, doi. 10.3390/ijms23010398
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- Publication type:
- Article
Inhibition of Ceramide Synthesis Reduces α-Synuclein Proteinopathy in a Cellular Model of Parkinson's Disease.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6469, doi. 10.3390/ijms22126469
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- Publication type:
- Article
Semisynthetic Modification of Tau Protein with Di-Ubiquitin Chains for Aggregation Studies.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4400, doi. 10.3390/ijms21124400
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- Publication type:
- Article
Parkinson's Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance.
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- Molecular Neurobiology, 2021, v. 58, n. 7, p. 3119, doi. 10.1007/s12035-021-02327-8
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- Publication type:
- Article
Diabetes Mellitus as a Risk Factor for Parkinson’s Disease: a Molecular Point of View.
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- Molecular Neurobiology, 2018, v. 55, n. 11, p. 8754, doi. 10.1007/s12035-018-1025-9
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- Publication type:
- Article
Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis.
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- Journal of Biological Inorganic Chemistry (JBIC), 2013, v. 18, n. 1, p. 81, doi. 10.1007/s00775-012-0951-7
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- Publication type:
- Article
Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease.
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- Acta Neuropathologica, 2022, v. 144, n. 1, p. 81, doi. 10.1007/s00401-022-02437-0
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- Publication type:
- Article
Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease.
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- Acta Neuropathologica, 2018, v. 136, n. 4, p. 621, doi. 10.1007/s00401-018-1892-1
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- Publication type:
- Article
USP14 inhibition corrects an in vivo model of impaired mitophagy.
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- EMBO Molecular Medicine, 2018, v. 10, n. 11, p. N.PAG, doi. 10.15252/emmm.201809014
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- Publication type:
- Article
Synthesis, Biodistribution and In vitro Evaluation of Brain Permeable High Affinity Type 2 Cannabinoid Receptor Agonists [<sup>11</sup>C]MA2 and [<sup>18</sup>F]MA3.
- Published in:
- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00431
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- Publication type:
- Article
LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-015-0066-z
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- Publication type:
- Article
Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease?
- Published in:
- Molecular Neurodegeneration, 2011, v. 6, n. 1, p. 6, doi. 10.1186/1750-1326-6-6
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- Publication type:
- Article
The struggle by Caenorhabditis elegans to maintain proteostasis during aging and disease.
- Published in:
- Biology Direct, 2016, v. 11, p. 1, doi. 10.1186/s13062-016-0161-2
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- Publication type:
- Article
Structure and topology of the non-amyloid-β component fragment of human α-synuclein bound to micelles: Implications for the aggregation process.
- Published in:
- Protein Science: A Publication of the Protein Society, 2006, v. 15, n. 6, p. 1408, doi. 10.1110/ps.052048706
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- Publication type:
- Article
Ditopic Chelators of Dicopper Centers for Enhanced Tyrosinases Inhibition.
- Published in:
- Chemistry - A European Journal, 2021, v. 27, n. 13, p. 4384, doi. 10.1002/chem.202004695
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- Publication type:
- Article
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex.
- Published in:
- Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00049
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- Publication type:
- Article
Site‐Specific Ubiquitination of Tau Amyloids Promoted by the E3 Ligase CHIP.
- Published in:
- Angewandte Chemie International Edition, 2023, v. 62, n. 50, p. 1, doi. 10.1002/anie.202310230
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- Publication type:
- Article
Water‐Soluble Melanin–Protein–Fe/Cu Conjugates Derived from Norepinephrine as Reliable Models for Neuromelanin of Human Brain Locus Coeruleus.
- Published in:
- Angewandte Chemie International Edition, 2022, v. 61, n. 32, p. 1, doi. 10.1002/anie.202204787
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- Publication type:
- Article
Photoresponsive Prion‐Mimic Foldamer to Induce Controlled Protein Aggregation.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 10, p. 5173, doi. 10.1002/anie.202012995
- By:
- Publication type:
- Article
Semisynthetic and Enzyme‐Mediated Conjugate Preparations Illuminate the Ubiquitination‐Dependent Aggregation of Tau Protein.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 16, p. 6607, doi. 10.1002/anie.201916756
- By:
- Publication type:
- Article
Single-Molecule-Level Evidence for the Osmophobic Effect.
- Published in:
- Angewandte Chemie, 2011, v. 123, n. 19, p. 4486, doi. 10.1002/ange.201006714
- By:
- Publication type:
- Article
DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease.
- Published in:
- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00485-1
- By:
- Publication type:
- Article
The potential convergence of NLRP3 inflammasome, potassium, and dopamine mechanisms in Parkinson's disease.
- Published in:
- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00293-z
- By:
- Publication type:
- Article
Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson's Disease.
- Published in:
- Aging & Disease, 2018, v. 9, n. 4, p. 716, doi. 10.14336/AD.2017.1018
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- Publication type:
- Article
α-Synuclein Oligomers Induced by Docosahexaenoic Acid Affect Membrane Integrity.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0082732
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- Publication type:
- Article
Triggering of Inflammasome by Aggregated α-Synuclein, an Inflammatory Response in Synucleinopathies.
- Published in:
- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0055375
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- Publication type:
- Article
Covalent α-Synuclein Dimers: Chemico-Physical and Aggregation Properties.
- Published in:
- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050027
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- Publication type:
- Article
Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043472
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- Publication type:
- Article
Human SOD2 Modification by Dopamine Quinones Affects Enzymatic Activity by Promoting Its Aggregation: Possible Implications for Parkinson’s Disease.
- Published in:
- PLoS ONE, 2012, v. 7, n. 6, p. e38026, doi. 10.1371/journal.pone.0038026
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- Publication type:
- Article