Works by Bua, Silvia

Results: 41

Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.

Published in:

Molecules, 2022, v. 27, n. 22, p. 7703, doi. 10.3390/molecules27227703

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ghabbour, Hazem A.;
Bua, Silvia;
Nocentini, Alessio;
Alkahtani, Hamad M.;
Alsaif, Nawaf A.;
Al-Agamy, Mohamed H. M.;
Supuran, Claudiu T.

Publication type:

Article

Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation.

Published in:

Molecules, 2020, v. 25, n. 10, p. 2347, doi. 10.3390/molecules25102347

By:

Anduran, Emilie;
Aspatwar, Ashok;
Parvathaneni, Nanda-Kumar;
Suylen, Dennis;
Bua, Silvia;
Nocentini, Alessio;
Parkkila, Seppo;
Supuran, Claudiu T.;
Dubois, Ludwig;
Lambin, Philippe;
Winum, Jean-Yves;
Carta, Fabrizio;
Angeli, Andrea

Publication type:

Article

Dual P-Glycoprotein and CA XII Inhibitors: A New Strategy to Reverse the P-gp Mediated Multidrug Resistance (MDR) in Cancer Cells †.

Published in:

Molecules, 2020, v. 25, n. 7, p. 1748, doi. 10.3390/molecules25071748

By:

Teodori, Elisabetta;
Braconi, Laura;
Bua, Silvia;
Lapucci, Andrea;
Bartolucci, Gianluca;
Manetti, Dina;
Romanelli, Maria Novella;
Dei, Silvia;
Supuran, Claudiu T.;
Coronnello, Marcella;
Ferreira, Maria José Umbelino

Publication type:

Article

Extending the Inhibition Profiles of Coumarin-Based Compounds Against Human Carbonic Anhydrases: Synthesis, Biological, and In Silico Evaluation.

Published in:

Molecules, 2019, v. 24, n. 19, p. 3580, doi. 10.3390/molecules24193580

By:

Kartsev, Victor;
Geronikaki, Athina;
Bua, Silvia;
Nocentini, Alessio;
Petrou, Anthi;
Lichitsky, Boris;
Frasinyuk, Mykhaylo;
Leitans, Janis;
Kazaks, Andris;
Tars, Kaspars;
Supuran, Claudiu T.

Publication type:

Article

Cloning, Characterization and Anion Inhibition Studies of a β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica.

Published in:

Molecules, 2018, v. 23, n. 12, p. 3112, doi. 10.3390/molecules23123112

By:

Haapanen, Susanna;
Bua, Silvia;
Kuuslahti, Marianne;
Parkkila, Seppo;
Supuran, Claudiu T.

Publication type:

Article

Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX.

Published in:

Molecules, 2018, v. 23, n. 1, p. 153, doi. 10.3390/molecules23010153

By:

Peperidou, Aikaterini;
Bua, Silvia;
Bozdag, Murat;
Hadjipavlou-Litina, Dimitra;
Supuran, Claudiu T.

Publication type:

Article

Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors.

Published in:

Molecules, 2017, v. 22, n. 7, p. 1049, doi. 10.3390/molecules22071049

By:

Berrino, Emanuela;
Bua, Silvia;
Mori, Mattia;
Botta, Maurizio;
Murthy, Vallabhaneni S.;
Vijayakumar, Vijayaparthasarathi;
Tamboli, Yasinalli;
Bartolucci, Gianluca;
Mugelli, Alessandro;
Cerbai, Elisabetta;
Supuran, Claudiu T.;
Carta, Fabrizio

Publication type:

Article

The production and biochemical characterization of α-carbonic anhydrase from Lactobacillus rhamnosus GG.

Published in:

Applied Microbiology & Biotechnology, 2022, v. 106, n. 11, p. 4065, doi. 10.1007/s00253-022-11990-3

By:

Urbański, Linda J.;
Bua, Silvia;
Angeli, Andrea;
Emameh, Reza Zolfaghari;
Barker, Harlan R.;
Kuuslahti, Marianne;
Hytönen, Vesa P.;
Parkkila, Seppo;
Supuran, Claudiu T.

Publication type:

Article

Natural Polyphenols Selectively Inhibit β‐Carbonic Anhydrase from the Dandruff‐Producing Fungus <italic>Malassezia globosa</italic>: Activity and Modeling Studies.

Published in:

ChemMedChem, 2018, v. 13, n. 8, p. 816, doi. 10.1002/cmdc.201800015

By:

Nocentini, Alessio;
Bua, Silvia;
Del Prete, Sonia;
Heravi, Yeganeh Entezari;
Saboury, Ali A.;
Karioti, Anastasia;
Bilia, Anna Rita;
Capasso, Clemente;
Gratteri, Paola;
Supuran, Claudiu T.

Publication type:

Article

Comparison of the Sulfonamide Inhibition Profiles of the α-Carbonic Anhydrase Isoforms (SpiCA1, SpiCA2 and SpiCA3) Encoded by the Genome of the Scleractinian Coral Stylophora pistillata.

Published in:

Marine Drugs, 2019, v. 17, n. 3, p. 146, doi. 10.3390/md17030146

By:

Del Prete, Sonia;
Bua, Silvia;
Alasmary, Fatmah A. S.;
AlOthman, Zeid;
Tambutté, Sylvie;
Zoccola, Didier;
Supuran, Claudiu T.;
Capasso, Clemente

Publication type:

Article

Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2584, doi. 10.3390/ijms25052584

By:

Bua, Silvia;
Bonardi, Alessandro;
Mük, Georgiana Ramona;
Nocentini, Alessio;
Gratteri, Paola;
Supuran, Claudiu T.

Publication type:

Article

The Effect of Substituted Benzene-Sulfonamides and Clinically Licensed Drugs on the Catalytic Activity of CynT2, a Carbonic Anhydrase Crucial for Escherichia coli Life Cycle.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 4175, doi. 10.3390/ijms21114175

By:

Del Prete, Sonia;
De Luca, Viviana;
Bua, Silvia;
Nocentini, Alessio;
Carginale, Vincenzo;
Supuran, Claudiu T.;
Capasso, Clemente

Publication type:

Article

Novel Diamide-Based Benzenesulfonamides as Selective Carbonic Anhydrase IX Inhibitors Endowed with Antitumor Activity: Synthesis, Biological Evaluation and In Silico Insights.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 10, p. 2484, doi. 10.3390/ijms20102484

By:

Abdelrahman, Mohamed A.;
Eldehna, Wagdy M.;
Nocentini, Alessio;
Bua, Silvia;
Al-Rashood, Sara T.;
Hassan, Ghada S.;
Bonardi, Alessandro;
Almehizia, Abdulrahman A.;
Alkahtani, Hamad M.;
Alharbi, Amal;
Gratteri, Paola;
Supuran, Claudiu T.

Publication type:

Article

Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2354, doi. 10.3390/ijms20092354

By:

Demir-Yazıcı, Kübra;
Bua, Silvia;
Akgüneş, Nurgül Mutlu;
Akdemir, Atilla;
Supuran, Claudiu T.;
Güzel-Akdemir, Özlen

Publication type:

Article

Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 5, p. 1208, doi. 10.3390/ijms20051208

By:

Buran, Kerem;
Bua, Silvia;
Poli, Giulio;
Önen Bayram, F. Esra;
Tuccinardi, Tiziano;
T. Supuran, Claudiu

Publication type:

Article

Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3946, doi. 10.3390/ijms19123946

By:

Bua, Silvia;
Haapanen, Susanna;
Kuuslahti, Marianne;
Parkkila, Seppo;
Supuran, Claudiu T.

Publication type:

Article

Comparison of the Anion Inhibition Profiles of the α-CA Isoforms (SpiCA1, SpiCA2 and SpiCA3) from the Scleractinian Coral Stylophora pistillata.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 7, p. 2128, doi. 10.3390/ijms19072128

By:

Del Prete, Sonia;
Capasso, Clemente;
Bua, Silvia;
Supuran, Claudiu T.;
Zoccola, Didier;
Techer, Nathalie;
Tambutté, Sylvie;
Alasmary, Fatmah A.S.;
AlOthman, Zeid;
Alqahtani, Linah S.

Publication type:

Article

Activation Studies of the β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica with Amino Acids and Amines.

Published in:

Metabolites (2218-1989), 2019, v. 9, n. 2, p. 26, doi. 10.3390/metabo9020026

By:

Bua, Silvia;
Haapanen, Susanna;
Kuuslahti, Marianne;
Parkkila, Seppo;
Supuran, Claudiu T.

Publication type:

Article

Structural and biochemical characterization of novel carbonic anhydrases from Phaeodactylum tricornutum.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2020, v. 76, n. 7, p. 676, doi. 10.1107/S2059798320007202

By:

Jin, Shengyang;
Vullo, Daniela;
Bua, Silvia;
Nocentini, Alessio;
Supuran, Claudiu T.;
Gao, Yong-gui

Publication type:

Article

Calixarenes Incorporating Sulfonamide Moieties: Versatile Ligands for Carbonic Anhydrases Inhibition.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 6, p. 1, doi. 10.1002/chem.202103527

By:

Sbravati, Davide;
Bonardi, Alessandro;
Bua, Silvia;
Angeli, Andrea;
Ferraroni, Marta;
Nocentini, Alessio;
Casnati, Alessandro;
Gratteri, Paola;
Sansone, Francesco;
Supuran, Claudiu T.

Publication type:

Article

Carbonic anhydrase inhibitory activity of phthalimide-capped benzene sulphonamide derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2235089

By:

Shilkar, Deepak;
Mohd Siddique, Mohd Usman;
Bua, Silvia;
Yasmin, Sabina;
Patil, Mrunali;
Timiri, Ajay Kumar;
Supuran, Claudiu T.;
Jayaprakash, Venkatesan

Publication type:

Article

The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 930, doi. 10.1080/14756366.2022.2053526

By:

Bonardi, Alessandro;
Bua, Silvia;
Combs, Jacob;
Lomelino, Carrie;
Andring, Jacob;
Osman, Sameh Mohamed;
Toti, Alessandra;
Di Cesare Mannelli, Lorenzo;
Gratteri, Paola;
Ghelardini, Carla;
McKenna, Robert;
Nocentini, Alessio;
Supuran, Claudiu T.

Publication type:

Article

Vanillin enones as selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. The out of the active site pocket for the design of selective inhibitors?

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 2118, doi. 10.1080/14756366.2021.1982933

By:

Riafrecha, Leonardo E.;
Le Pors, Macarena S.;
Lavecchia, Martín J.;
Bua, Silvia;
Supuran, Claudiu T.;
Colinas, Pedro A.

Publication type:

Article

Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1834, doi. 10.1080/14756366.2020.1826942

By:

Urbanski, Linda J.;
Bua, Silvia;
Angeli, Andrea;
Kuuslahti, Marianne;
Hytönen, Vesa. P.;
Supuran, Claudiu T.;
Parkkila, Seppo

Publication type:

Article

Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1765, doi. 10.1080/14756366.2020.1822829

By:

Aspatwar, Ashok;
Berrino, Emanuela;
Bua, Silvia;
Carta, Fabrizio;
Capasso, Clemente;
Parkkila, Seppo;
Supuran, Claudiu T.

Publication type:

Article

Escherichia coliγ-carbonic anhydrase: characterisation and effects of simple aromatic/heterocyclic sulphonamide inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1545, doi. 10.1080/14756366.2020.1800670

By:

Del Prete, Sonia;
Bua, Silvia;
Supuran, Claudiu T.;
Capasso, Clemente

Publication type:

Article

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 733, doi. 10.1080/14756366.2020.1742117

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Bua, Silvia;
Nocentini, Alessio;
AlSaif, Nawaf A.;
Alanazi, Mohammed M.;
El-Gendy, Manal A.;
Ahmed, Hany E. A.;
Supuran, Claudiu T.

Publication type:

Article

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1697, doi. 10.1080/14756366.2019.1666836

By:

Milite, Ciro;
Amendola, Giorgio;
Nocentini, Alessio;
Bua, Silvia;
Cipriano, Alessandra;
Barresi, Elisabetta;
Feoli, Alessandra;
Novellino, Ettore;
Da Settimo, Federico;
Supuran, Claudiu T.;
Castellano, Sabrina;
Cosconati, Sandro;
Taliani, Sabrina

Publication type:

Article

Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1457, doi. 10.1080/14756366.2019.1652282

By:

Al-Sanea, Mohammad M.;
Elkamhawy, Ahmed;
Paik, Sora;
Bua, Silvia;
Ha Lee, So;
Abdelgawad, Mohamed A.;
Roh, Eun Joo;
Eldehna, Wagdy M.;
Supuran, Claudiu T.

Publication type:

Article

Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1193, doi. 10.1080/14756366.2019.1630616

By:

Akocak, Suleyman;
Lolak, Nabih;
Bua, Silvia;
Nocentini, Alessio;
Supuran, Claudiu T.

Publication type:

Article

Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 1575, doi. 10.1080/14756366.2018.1515933

By:

Akocak, Suleyman;
Lolak, Nabih;
Bua, Silvia;
Supuran, Claudiu T.

Publication type:

Article

Synthesis, X-ray structure, in silico calculation, and carbonic anhydrase inhibitory properties of benzylimidazole metal complexes.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 1150, doi. 10.1080/14756366.2018.1481404

By:

Bouchouit, Mehdi;
Bouacida, Sofiane;
Zouchoune, Bachir;
Merazig, Hocine;
Bua, Silvia;
Bouaziz, Zouhair;
Le Borgne, Marc;
Supuran, Claudiu T.;
Bouraiou, Abdelmalek

Publication type:

Article

Evaluation of sulphonamide derivatives acting as inhibitors of human carbonic anhydrase isoforms I, II and Mycobacterium tuberculosis β-class enzyme Rv3273.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 962, doi. 10.1080/14756366.2018.1471475

By:

Wani, Tanvi V.;
Bua, Silvia;
Khude, Pravin S.;
Chowdhary, Abdul H.;
Supuran, Claudiu T.;
Toraskar, Mrunmayee P.

Publication type:

Article

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 1125, doi. 10.1080/14756366.2018.1467901

By:

Bua, Silvia;
Berrino, Emanuela;
Del Prete, Sonia;
Murthy, Vallabhaneni S.;
Vijayakumar, Vijayaparthasarathi;
Tamboli, Yasinalli;
Capasso, Clemente;
Cerbai, Elisabetta;
Mugelli, Alessandro;
Carta, Fabrizio;
Supuran, Claudiu T.

Publication type:

Article

Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 707, doi. 10.1080/14756366.2018.1450400

By:

Bua, Silvia;
Bozdag, Murat;
Del Prete, Sonia;
Carta, Fabrizio;
Donald, William A.;
Capasso, Clemente;
Supuran, Claudiu T.

Publication type:

Article

Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 629, doi. 10.1080/14756366.2018.1446432

By:

Awadallah, Fadi M.;
Bua, Silvia;
Mahmoud, Walaa R.;
Nada, Hossam H.;
Nocentini, Alessio;
Supuran, Claudiu T.

Publication type:

Article

Resolution of co-eluting isomers of anti-inflammatory drugs conjugated to carbonic anhydrase inhibitors from plasma in liquid chromatography by energy-resolved tandem mass spectrometry.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 671, doi. 10.1080/14756366.2018.1445737

By:

Menicatti, Marta;
Pallecchi, Marco;
Bua, Silvia;
Vullo, Daniela;
Di Cesare Mannelli, Lorenzo;
Ghelardini, Carla;
Carta, Fabrizio;
Supuran, Claudiu T.;
Bartolucci, Gianluca

Publication type:

Article

Synthesis and biological evaluation of benzenesulphonamide-bearing 1,4,5-trisubstituted-1,2,3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 1187, doi. 10.1080/14756366.2017.1367775

By:

Kumar, Rajiv;
Sharma, Vikas;
Bua, Silvia;
Supuran, Claudiu T.;
Sharma, Pawan K.

Publication type:

Article

Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 885, doi. 10.1080/14756366.2017.1337759

By:

Bozdag, Murat;
Bua, Silvia;
Osman, Sameh M.;
AlOthman, Zeid;
Supuran, Claudiu T.

Publication type:

Article

Advances in new psychoactive substances identification: the U.R.I.To.N. Consortium.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 841, doi. 10.1080/14756366.2017.1333987

By:

Bertol, Elisabetta;
Vaiano, Fabio;
Mari, Francesco;
Di Milia, Maria Grazia;
Bua, Silvia;
Supuran, Claudiu T.;
Carta, Fabrizio

Publication type:

Article

Diagnostic markers for glaucoma: a patent and literature review (2013-2019).

Published in:

Expert Opinion on Therapeutic Patents, 2019, v. 29, n. 10, p. 829, doi. 10.1080/13543776.2019.1667336

By:

Bua, Silvia;
Supuran, Claudiu T

Publication type:

Article