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A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
- Published in:
- Nature, 2004, v. 428, n. 6981, p. 431, doi. 10.1038/nature02371
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- Publication type:
- Article
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-?B.
- Published in:
- Nature, 2003, v. 424, n. 6950, p. 797, doi. 10.1038/nature01811
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- Publication type:
- Article
A generic strategy for CRISPR-Cas9-mediated gene tagging.
- Published in:
- Nature Communications, 2015, v. 6, n. 12, p. 10237, doi. 10.1038/ncomms10237
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- Article
Quantitative genetic screening reveals a Ragulator-FLCN feedback loop that regulates the mTORC1 pathway.
- Published in:
- Science Signaling, 2020, v. 13, n. 649, p. 1, doi. 10.1126/scisignal.aba5665
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- Article
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.
- Published in:
- Nature, 2011, v. 477, n. 7364, p. 340, doi. 10.1038/nature10348
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- Article
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223.
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- Nature, 2008, v. 451, n. 7182, p. 1125, doi. 10.1038/nature06607
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- Publication type:
- Article
E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains.
- Published in:
- Oncogene, 2004, v. 23, n. 30, p. 5138, doi. 10.1038/sj.onc.1207649
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- Article
MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors.
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- Nature Genetics, 2013, v. 45, n. 1, p. 104, doi. 10.1038/ng.2471
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- Article
Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.11785
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- Article
Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.08467
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- Article
BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-07927-y
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- Publication type:
- Article
Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.
- Published in:
- Nature Biotechnology, 2011, v. 29, n. 6, p. 542, doi. 10.1038/nbt.1857
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- Article
MND1 enables homologous recombination in somatic cells primarily outside the context of replication.
- Published in:
- Molecular Oncology, 2023, v. 17, n. 7, p. 1192, doi. 10.1002/1878-0261.13448
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- Publication type:
- Article
Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents.
- Published in:
- Molecular Oncology, 2018, v. 12, n. 6, p. 953, doi. 10.1002/1878-0261.12307
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- Publication type:
- Article
A Reporter Screen in a Human Haploid Cell Line Identifies CYLD as a Constitutive Inhibitor of NF-κB.
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- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0070339
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- Article
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G<sub>2</sub>/M DNA Damage Checkpoint.
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- PLoS Biology, 2010, v. 8, n. 1, p. 1, doi. 10.1371/journal.pbio.1000287
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- Article
New tools for functional mammalian cancer genetics.
- Published in:
- 2003
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- Publication type:
- research
A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.
- Published in:
- Nature Cell Biology, 2013, v. 15, n. 12, p. 1473, doi. 10.1038/ncb2865
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- Publication type:
- Article
A Mediator-cohesin axis controls heterochromatin domain formation.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28377-7
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- Publication type:
- Article
Decoding microtubule detyrosination: enzyme families, structures, and functional implications.
- Published in:
- FEBS Letters, 2024, v. 598, n. 12, p. 1453, doi. 10.1002/1873-3468.14940
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- Publication type:
- Article
Ebola virus entry requires the host-programmed recognition of an intracellular receptor.
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- EMBO Journal, 2012, v. 31, n. 8, p. 1947, doi. 10.1038/emboj.2012.53
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- Article
B3GALNT2 mutations associated with nonsyndromic autosomal recessive intellectual disability reveal a lack of genotype- phenotype associations in the muscular dystrophy-dystroglycanopathies.
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- Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-017-0505-2
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- Publication type:
- Article
SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing.
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- PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0212053
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- Article
shRNA libraries and their use in cancer genetics.
- Published in:
- Nature Methods, 2006, v. 3, n. 9, p. 701, doi. 10.1038/nmeth921
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- Publication type:
- Article
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector.
- Published in:
- EMBO Reports, 2003, v. 4, n. 6, p. 609, doi. 10.1038/sj.embor.embor865
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- Publication type:
- Article
Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.
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- EMBO Journal, 2015, v. 34, n. 24, p. 2993, doi. 10.15252/embj.201592409
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- Publication type:
- Article
The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity.
- Published in:
- Nature Chemical Biology, 2014, v. 10, n. 9, p. 768, doi. 10.1038/nchembio.1590
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- Publication type:
- Article
An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors.
- Published in:
- Nature Chemical Biology, 2006, v. 2, n. 4, p. 202, doi. 10.1038/nchembio774
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- Publication type:
- Article