Works by Brumell, John H.

Results: 60

Bacteria-autophagy interplay: a battle for survival.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 2, p. 101, doi. 10.1038/nrmicro3160

By:

Huang, Ju;
Brumell, John H.

Publication type:

Article

Erratum.

Published in:

2003

By:

Brumell, John H.;
Kujat-Choy, Sonya;
Brown, Nat F.;
Vallance, Bruce A.;
Knodler, Leigh A.;
Finlay, B. Brett

Publication type:

Erratum

SopD2 is a Novel Type III Secreted Effector of Salmonella typhimurium That Targets Late Endocytic Compartments Upon Delivery Into Host Cells.

Published in:

Traffic, 2003, v. 4, n. 1, p. 36, doi. 10.1034/j.1600-0854.2003.40106.x

By:

Brumell, John H.;
Kujat-Choy, Sonya;
Brown, Nat F.;
Vallance, Bruce A.;
Knodler, Leigh A.;
Finlay, B. Brett

Publication type:

Article

SifA, a Type III Secreted Effector of Salmonella typhimurium , DirectsSalmonella -Induced Filament (Sif) Formation Along Microtubules.

Published in:

Traffic, 2002, v. 3, n. 6, p. 407, doi. 10.1034/j.1600-0854.2002.30604.x

By:

Brumell, John H;
Goosney, Danika L;
Finlay, B. Brett

Publication type:

Article

Characterization of Salmonella-Induced Filaments (Sifs) Reveals a Delayed Interaction Between Salmonella-Containing Vacuoles and Late Endocytic Compartments.

Published in:

Traffic, 2001, v. 2, n. 9, p. 643, doi. 10.1034/j.1600-0854.2001.20907.x

By:

Brumell, John H.;
Tang, Patrick;
Mills, Scott D.;
Finlay, B. Brett

Publication type:

Article

Salmonella exploits LRRK2-dependent plasma membrane dynamics to invade host cells.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57453-x

By:

Zhu, Hongxian;
Sydor, Andrew M.;
Yan, Bing-Ru;
Li, Ren;
Boniecki, Michal T.;
Lyons, Carina;
Cygler, Miroslaw;
Muise, Aleixo M.;
Maxson, Michelle E.;
Grinstein, Sergio;
Raught, Brian;
Brumell, John H.

Publication type:

Article

Citrobacter rodentium Infection Induces MyD88-Dependent Formation of Ubiquitinated Protein Aggregates in the Intestinal Epithelium.

Published in:

Journal of Innate Immunity, 2010, v. 3, n. 1, p. 83, doi. 10.1159/000320644

By:

Kaniuk, Natalia A.;
Lam, Grace Y.;
Ma, Caixia;
Galindo-Mata, Esther;
Jones, Nicola;
Vallance, Bruce A.;
Brumell, John H.

Publication type:

Article

Cell biology: A Listeria escape trick.

Published in:

Nature, 2008, v. 455, n. 7217, p. 1186, doi. 10.1038/4551186a

By:

Lam, Grace Y.;
Brumell, John H.

Publication type:

Article

Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles.

Published in:

Nature, 2008, v. 451, n. 7176, p. 350, doi. 10.1038/nature06479

By:

Birmingham, Cheryl L.;
Canadien, Veronica;
Kaniuk, Natalia A.;
Steinberg, Benjamin E.;
Higgins, Darren E.;
Brumell, John H.

Publication type:

Article

SLIT2/ROBO1 signaling suppresses mTORC1 for organelle control and bacterial killing.

Published in:

Life Science Alliance, 2023, v. 6, n. 8, p. 1, doi. 10.26508/lsa.202301964

By:

Bhosle, Vikrant K.;
Joel MJ Tan;
Taoyingnan Li;
Rong Hua;
Hyunwoo Kwon;
Zhubing Li;
Patel, Sajedabanu;
Tessier-Lavigne, Marc;
Robinson, Lisa A.;
Kim, Peter K.;
Brumell, John H.

Publication type:

Article

The related effector proteins SopD and SopD2 fromSalmonella entericaserovar Typhimurium contribute to virulence during systemic infection of mice.

Published in:

Molecular Microbiology, 2004, v. 54, n. 5, p. 1186, doi. 10.1111/j.1365-2958.2004.04344.x

By:

Xiuju Jiang;
Rossanese, Olivia W.;
Brown, Nat F.;
Kujat-Choy, Sonya;
Galán, Jorge E.;
Finlay, B. Brett;
Brumell, John H.

Publication type:

Article

Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24982-0

By:

Tan, Joel M. J.;
Garner, Monica E.;
Regeimbal, James M.;
Greene, Catherine J.;
Márquez, Jorge D. Rojas;
Ammendolia, Dustin A.;
McCluggage, Adam R. R.;
Li, Taoyingnan;
Wu, Katherine J.;
Cemma, Marija;
Ostrowski, Philip P.;
Raught, Brian;
Diamond, Michael S.;
Grinstein, Sergio;
Yates, Robin M.;
Higgins, Darren E.;
Brumell, John H.

Publication type:

Article

Salmonella effector SopD promotes plasma membrane scission by inhibiting Rab10.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24983-z

By:

Boddy, Kirsten C.;
Zhu, Hongxian;
D'Costa, Vanessa M.;
Xu, Caishuang;
Beyrakhova, Ksenia;
Cygler, Miroslaw;
Grinstein, Sergio;
Coyaud, Etienne;
Laurent, Estelle M. N.;
St-Germain, Jonathan;
Raught, Brian;
Brumell, John H.

Publication type:

Article

SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34.

Published in:

Journal of Cell Biology, 2008, v. 182, n. 4, p. 741, doi. 10.1083/jcb.200804131

By:

Mallo, Gustavo V.;
Espina, Marianela;
Smith, Adam C.;
Terebiznik, Mauricio R.;
Alemán, Ainel;
Finlay, B. Brett;
Rameh, Lucia E.;
Grinstein, Sergio;
Brumell, John H.

Publication type:

Article

A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium.

Published in:

Journal of Cell Biology, 2007, v. 176, n. 3, p. 263, doi. 10.1083/jcb.200611056

By:

Smith, Adam C.;
Do Heo, Won;
Braun, Virginie;
Jiang, Xiuju;
Macrae, Chloe;
Casanova, James E.;
Scidmore, Marci A.;
Grinstein, Sergio;
Meyer, Tobias;
Brumell, John H.

Publication type:

Article

Rab7 and Arl8 GTPases are Necessary for Lysosome Tubulation in Macrophages.

Published in:

Traffic, 2012, v. 13, n. 12, p. 1667, doi. 10.1111/tra.12003

By:

Mrakovic, Amra;
Kay, Jason G.;
Furuya, Wendy;
Brumell, John H.;
Botelho, Roberto J.

Publication type:

Article

Salmonella-Containing Vacuoles: Directing Traffic and Nesting to Grow.

Published in:

Traffic, 2008, v. 9, n. 12, p. 2022, doi. 10.1111/j.1600-0854.2008.00827.x

By:

Bakowski, Malina A.;
Braun, Virginie;
Brumell, John H.

Publication type:

Article

Association Between a Multi-Locus Genetic Risk Score and Inflammatory Bowel Disease.

Published in:

Bioinformatics & Biology Insights, 2013, n. 7, p. 143, doi. 10.4137/BBI.S11601

By:

Pingzhao Hu;
Muise, Aleixo M.;
Xiang Xing;
Brumell, John H.;
Silverberg, Mark S.;
Wei Xu

Publication type:

Article

Global Proximity Interactome of the Human Macroautophagy Pathway.

Published in:

Autophagy, 2022, v. 18, n. 5, p. 1174, doi. 10.1080/15548627.2021.1965711

By:

Tu, Yi Xin;
Sydor, Andrew M.;
Coyaud, Etienne;
Laurent, Estelle M. N.;
Dyer, Diana;
Mellouk, Nora;
St-Germain, Jonathan;
Vernon, Robert M.;
Forman-Kay, Julie D.;
Li, Taoyingnan;
Hua, Rong;
Zhao, Kexin;
Ridgway, Neale D.;
Kim, Peter K.;
Raught, Brian;
Brumell, John H.

Publication type:

Article

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

Published in:

Autophagy, 2022, v. 18, n. 4, p. 829, doi. 10.1080/15548627.2021.1960116

By:

Yan, Bing-Ru;
Li, Taoyingnan;
Coyaud, Etienne;
Laurent, Estelle M. N.;
St-Germain, Jonathan;
Zhou, Yuhuan;
Kim, Peter K.;
Raught, Brian;
Brumell, John H.

Publication type:

Article

An autophagy-independent role for ATG16L1: promoting lysosome-mediated plasma membrane repair.

Published in:

Autophagy, 2019, v. 15, n. 5, p. 932, doi. 10.1080/15548627.2019.1586261

By:

Tan, Joel M. J.;
Mellouk, Nora;
Brumell, John H.

Publication type:

Article

Systematic profiling of the chicken gut microbiome reveals dietary supplementation with antibiotics alters expression of multiple microbial pathways with minimal impact on community structure.

Published in:

Microbiome, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40168-022-01319-7

By:

Zou, Angela;
Nadeau, Kerry;
Xiong, Xuejian;
Wang, Pauline W.;
Copeland, Julia K.;
Lee, Jee Yeon;
Pierre, James St.;
Ty, Maxine;
Taj, Billy;
Brumell, John H.;
Guttman, David S.;
Sharif, Shayan;
Korver, Doug;
Parkinson, John

Publication type:

Article

SopD acts cooperatively with SopB during Salmonella enterica serovar Typhimurium invasion.

Published in:

Cellular Microbiology, 2007, v. 9, n. 12, p. 2839, doi. 10.1111/j.1462-5822.2007.01000.x

By:

Bakowski, Malina A.;
Cirulis, Judith T.;
Brown, Nat F.;
Finlay, B. Brett;
Brumell, John H.

Publication type:

Article

Arrested maturation of Neisseria-containing phagosomes in the absence of the lysosome-associated membrane proteins, LAMP-1 and LAMP-2.

Published in:

Cellular Microbiology, 2007, v. 9, n. 9, p. 2153, doi. 10.1111/j.1462-5822.2007.00946.x

By:

Binker, Marcelo G.;
Cosen-Binker, Laura I.;
Terebiznik, Mauricio R.;
Mallo, Gustavo V.;
McCaw, Shannon E.;
Eskelinen, Eeva-Liisa;
Willenborg, Marion;
Brumell, John H.;
Saftig, Paul;
Grinstein, Sergio;
Gray-Owen, Scott D.

Publication type:

Article

Role of lipid-mediated signal transduction in bacterial internalization.

Published in:

Cellular Microbiology, 2003, v. 5, n. 5, p. 287, doi. 10.1046/j.1462-5822.2003.00273.x

By:

Brumell, John H.;
Grinstein, Sergio

Publication type:

Article

The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells.

Published in:

Cellular Microbiology, 2002, v. 4, n. 1, p. 43, doi. 10.1046/j.1462-5822.2002.00170.x

By:

Steele-Mortimer, Olivia;
Brumell, John H;
Knodler, Leigh A;
Méresse, Stephane;
Lopez, Ana;
Finlay, B. Brett

Publication type:

Article

SifA permits survival and replication of Salmonella typhimurium in murine macrophages.

Published in:

Cellular Microbiology, 2001, v. 3, n. 2, p. 75, doi. 10.1046/j.1462-5822.2001.00087.x

By:

Brumell, John H.;
Rosenberger, Carrie M.;
Gotto, Geoffrey T.;
Marcus, Sandra L.;
Finlay, B. Brett

Publication type:

Article

Salmonella exploits membrane reservoirs for invasion of host cells.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47183-x

By:

Zhu, Hongxian;
Sydor, Andrew M.;
Boddy, Kirsten C.;
Coyaud, Etienne;
Laurent, Estelle M. N.;
Au, Aaron;
Tan, Joel M. J.;
Yan, Bing-Ru;
Moffat, Jason;
Muise, Aleixo M.;
Yip, Christopher M.;
Grinstein, Sergio;
Raught, Brian;
Brumell, John H.

Publication type:

Article

Bacterial subversion of host cytoskeletal machinery: Hijacking formins and the Arp2/3 complex.

Published in:

BioEssays, 2014, v. 36, n. 7, p. 687, doi. 10.1002/bies.201400038

By:

Truong, Dorothy;
Copeland, John W.;
Brumell, John H.

Publication type:

Article

Plasma membrane integrity: implications for health and disease.

Published in:

BMC Biology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12915-021-00972-y

By:

Ammendolia, Dustin A.;
Bement, William M.;
Brumell, John H.

Publication type:

Article

Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.

Published in:

PLoS Pathogens, 2015, v. 11, n. 8, p. 1, doi. 10.1371/journal.ppat.1005107

By:

Sit, Brandon;
Crowley, Shauna M.;
Bhullar, Kirandeep;
Lai, Christine Chieh-Lin;
Tang, Calvin;
Hooda, Yogesh;
Calmettes, Charles;
Khambati, Husain;
Ma, Caixia;
Brumell, John H.;
Schryvers, Anthony B.;
Vallance, Bruce A.;
Moraes, Trevor F.

Publication type:

Article

Structural and Biochemical Characterization of SrcA, a Multi-Cargo Type III Secretion Chaperone in Salmonella Required for Pathogenic Association with a Host.

Published in:

PLoS Pathogens, 2010, v. 6, n. 2, p. 1, doi. 10.1371/journal.ppat.1000751

By:

Cooper, Colin A.;
Kun Zhang;
Andres, Sara N.;
Yuan Fang;
Kaniuk, Natalia A.;
Hannemann, Mandy;
Brumell, John H.;
Foster, Leonard J.;
Junop, Murray S.;
Coombes, Brian K.

Publication type:

Article

Lysosomal pH Plays a Key Role in Regulation of mTOR Activity in Osteoclasts.

Published in:

Journal of Cellular Biochemistry, 2016, v. 117, n. 2, p. 413, doi. 10.1002/jcb.25287

By:

Hu, Yingwei;
Carraro‐Lacroix, Luciene R.;
Wang, Andrew;
Owen, Celeste;
Bajenova, Elena;
Corey, Paul N.;
Brumell, John H.;
Voronov, Irina

Publication type:

Article

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 2, p. 367, doi. 10.1083/jcb.201608128

By:

Rong Hua;
Cheng, Derrick;
Coyaud, Étienne;
Freeman, Spencer;
Di Pietro, Erminia;
Yuqing Wang;
Vissa, Adriano;
Yip, Christopher M.;
Fairn, Gregory D.;
Braverman, Nancy;
Brumell, John H.;
Trimble, William S.;
Raught, Brian;
Kim, Peter K.

Publication type:

Article

HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.

Published in:

Nature Communications, 2014, v. 5, n. 3, p. 3430, doi. 10.1038/ncomms4430

By:

Zhang, Liyong;
Chen, Xin;
Sharma, Parveen;
Moon, Mark;
Sheftel, Alex D.;
Dawood, Fayez;
Nghiem, Mai P.;
Wu, Jun;
Li, Ren-Ke;
Gramolini, Anthony O.;
Sorensen, Poul H.;
Penninger, Josef M.;
Brumell, John H.;
Liu, Peter P.

Publication type:

Article

The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders.

Published in:

Autophagy, 2017, v. 13, n. 5, p. 868, doi. 10.1080/15548627.2017.1291470

By:

Law, Kelsey B.;
Bronte-Tinkew, Dana;
Di Pietro, Erminia;
Snowden, Ann;
Jones, Richard O.;
Moser, Ann;
Brumell, John H.;
Braverman, Nancy;
Kim, Peter K.

Publication type:

Article

Autophagy proteins are not universally required for phagosome maturation.

Published in:

Autophagy, 2016, v. 12, n. 9, p. 1440, doi. 10.1080/15548627.2016.1191724

By:

Cemma, Marija;
Grinstein, Sergio;
Brumell, John H.

Publication type:

Article

Host and bacterial factors that regulate LC3 recruitment to Listeria monocytogenes during the early stages of macrophage infection.

Published in:

Autophagy, 2013, v. 9, n. 7, p. 985, doi. 10.4161/auto.24406

By:

Lam, Grace Y.;
Cemma, Marija;
Muise, Aleixo M.;
Higgins, Darren E.;
Brumell, John H.

Publication type:

Article

Receptor protein complexes are in control of autophagy.

Published in:

Autophagy, 2012, v. 8, n. 11, p. 1701, doi. 10.4161/auto.21332

By:

Mijaljica, Dalibor;
Nazarko, Taras Y.;
Brumell, John H.;
Wei-Pang Huang;
Komatsu, Masaaki;
Prescott, Mark;
Simonsen, Anne;
Yamamoto, Ai;
Hong Zhang;
Klionsky, Daniel J.;
Devenish, Rodney J.

Publication type:

Article

A comprehensive glossary of autophagy-related molecules and processes (2nd edition).

Published in:

Autophagy, 2011, v. 7, n. 11, p. 1273, doi. 10.4161/auto.7.11.17661

By:

Klionsky, Daniel J.;
Baehrecke, Eric H.;
Brumell, John H.;
Chu, Charleen T.;
Codogno, Patrice;
Cuervo, Ana Maria;
Debnath, Jayanta;
Deretic, Vojo;
Elazar, Zvulun;
Eskelinen, Eeva-Liisa;
Finkbeiner, Steven;
Fueyo-Margareto, Juan;
Gewirtz, David;
Jäättelä, Marja;
Kroemer, Guido;
Levine, Beth;
Melia, Thomas J.;
Mizushima, Noboru;
Rubinsztein, David C.;
Simonsen, Anne

Publication type:

Article

Bacterial toxins can inhibit host cell autophagy through cAMP generation.

Published in:

Autophagy, 2011, v. 7, n. 9, p. 957, doi. 10.4161/auto.7.9.16435

By:

Shahnazari, Shahab;
Namolovan, Anton;
Mogridge, Jeremy;
Kim, Peter K.;
Brumell, John H.

Publication type:

Article

A role for diacylglycerol in antibacterial autophagy.

Published in:

Autophagy, 2011, v. 7, n. 3, p. 331, doi. 10.4161/auto.7.3.14045

By:

Shahnazari, Shahab;
Namolovan, Anton;
Klionsky, Daniel J.;
Brumell, John H.

Publication type:

Article

Antibacterial autophagy occurs at PtdIns(3)Penriched domains of the endoplasmic reticulum and requires Rab1 GTPase.

Published in:

Autophagy, 2011, v. 7, n. 1, p. 17, doi. 10.4161/auto.7.1.13840

By:

Ju Huang;
Birmingham, Cheryl L.;
Shahnazari, Shahab;
Shiu, Jessica;
Zheng, Yiyu T.;
Smith, Adam C.;
Campellone, Kenneth G.;
Heo, Won Do;
Gruenheid, Samantha;
Meyer, Tobias;
Welch, Matthew D.;
Ktistakis, Nicholas T.;
Kim, Peter K.;
Klionsky, Daniel J.;
Brumell, John H.

Publication type:

Article

Salmonella exploits host Rho GTPase signalling pathways through the phosphatase activity of SopB.

Published in:

Cellular Microbiology, 2018, v. 20, n. 10, p. 1, doi. 10.1111/cmi.12938

By:

Truong, Dorothy;
Boddy, Kirsten C.;
Canadien, Veronica;
Brabant, Danielle;
Fairn, Gregory D.;
D'Costa, Vanessa M.;
Coyaud, Etienne;
Raught, Brian;
Pérez‐Sala, Dolores;
Park, Wei Sun;
Heo, Won Do;
Grinstein, Sergio;
Brumell, John H.

Publication type:

Article

Septin‐regulated actin dynamics promote Salmonella invasion of host cells.

Published in:

Cellular Microbiology, 2018, v. 20, n. 10, p. 1, doi. 10.1111/cmi.12866

By:

Boddy, Kirsten C.;
Gao, Aggie Duan;
Truong, Dorothy;
Kim, Moshe S.;
Froese, Carol D.;
Trimble, William S.;
Brumell, John H.

Publication type:

Article

Type I interferon promotes cell-to-cell spread of Listeria monocytogenes.

Published in:

Cellular Microbiology, 2017, v. 19, n. 3, p. n/a, doi. 10.1111/cmi.12660

By:

Osborne, Suzanne E.;
Sit, Brandon;
Shaker, Andrew;
Currie, Elissa;
Tan, Joël M.J.;
Rijn, Jorik;
Higgins, Darren E.;
Brumell, John H.

Publication type:

Article

Formin-mediated actin polymerization promotes Salmonella invasion.

Published in:

Cellular Microbiology, 2013, v. 15, n. 12, p. 2051, doi. 10.1111/cmi.12173

By:

Truong, Dorothy;
Brabant, Danielle;
Bashkurov, Mikhail;
Wan, Leo C. K.;
Braun, Virginie;
Heo, Won Do;
Meyer, Tobias;
Pelletier, Laurence;
Copeland, John;
Brumell, John H.

Publication type:

Article

Salmonella exploits Arl8B-directed kinesin activity to promote endosome tubulation and cell-to-cell transfer.

Published in:

Cellular Microbiology, 2011, v. 13, n. 11, p. 1812, doi. 10.1111/j.1462-5822.2011.01663.x

By:

Kaniuk, Natalia A.;
Canadien, Veronica;
Bagshaw, Richard D.;
Bakowski, Malina;
Braun, Virginie;
Landekic, Marija;
Mitra, Shuvadeep;
Huang, Ju;
Heo, Won Do;
Meyer, Tobias;
Pelletier, Laurence;
Andrews-Polymenis, Helene;
McClelland, Michael;
Pawson, Tony;
Grinstein, Sergio;
Brumell, John H.

Publication type:

Article

Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole.

Published in:

Cellular Microbiology, 2010, v. 12, n. 9, p. 1352, doi. 10.1111/j.1462-5822.2010.01476.x

By:

Braun, Virginie;
Wong, Anthony;
Landekic, Marija;
Wan Jin Hong;
Grinstein, Sergio;
Brumell, John H.

Publication type:

Article

The Diaphanous-Related Formins Promote Protrusion Formation and Cell-to-Cell Spread of Listeria monocytogenes.

Published in:

Journal of Infectious Diseases, 2015, v. 211, n. 7, p. 1185, doi. 10.1093/infdis/jiu546

By:

Fattouh, Ramzi;
Hyunwoo Kwon;
Czuczman, Mark A.;
Copeland, John W.;
Pelletier, Laurence;
Quinlan, Margot E.;
Muise, Aleixo M.;
Higgins, Darren E.;
Brumell, John H.

Publication type:

Article