Works by Bruhn, David F.

Results: 13

Goondicones A–H: Spiro-Isoindolinone Heartworm Anthelmintics from an Australian Pasture-Soil-Derived Streptomyces sp.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 12, p. 1222, doi. 10.3390/antibiotics13121222

By:

Han, Jianying;
Bruhn, David F.;
Childs, Cynthia T.;
Moreno, Yovany;
Salim, Angela A.;
Wu, Taizong;
Capon, Robert J.

Publication type:

Article

Goondapyrones A–J: Polyketide α and γ Pyrone Anthelmintics from an Australian Soil-Derived Streptomyces sp.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 10, p. 989, doi. 10.3390/antibiotics13100989

By:

Jin, Shengbin;
Bruhn, David F.;
Childs, Cynthia T.;
Burkman, Erica;
Moreno, Yovany;
Salim, Angela A.;
Khalil, Zeinab G.;
Capon, Robert J.

Publication type:

Article

Design, synthesis and microbiological evaluation of ampicillin-tetramic acid hybrid antibiotics.

Published in:

Journal of Antibiotics, 2017, v. 70, n. 1, p. 65, doi. 10.1038/ja.2016.52

By:

Cherian, Philip T;
Deshpande, Aditi;
Cheramie, Martin N;
Bruhn, David F;
Hurdle, Julian G;
Lee, Richard E

Publication type:

Article

Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agents.

Published in:

Journal of Antibiotics, 2013, v. 66, n. 6, p. 319, doi. 10.1038/ja.2013.21

By:

Shen, Li;
M Maddox, Marcus;
Adhikari, Sudip;
Bruhn, David F;
Kumar, Manish;
Lee, Robin E;
Hurdle, Julian G;
Lee, Richard E;
Sun, Dianqing

Publication type:

Article

Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections.

Published in:

Science Translational Medicine, 2015, v. 7, n. 288, p. 1, doi. 10.1126/scitranslmed.3010572

By:

Bruhn, David F.;
Waidyarachchi, Samanthi L.;
Madhura, Dora B.;
Shcherbakov, Dimitri;
Zhong Zheng;
Jiuyu Liu;
Abdelrahman, Yasser M.;
Singh, Aman P.;
Duscha, Stefan;
Rathi, Chetan;
Lee, Robin B.;
Belland, Robert J.;
Meibohm, Bernd;
Rosch, Jason W.;
Böttger, Erik C.;
Lee, Richard E.

Publication type:

Article

Mitochondrial DNA polymerase POLIB is essential for minicircle DNA replication in African trypanosomes.

Published in:

Molecular Microbiology, 2010, v. 75, n. 6, p. 1414, doi. 10.1111/j.1365-2958.2010.07061.x

By:

Bruhn, David F.;
Mozeleski, Brian;
Falkin, Laurie;
Klingbeil, Michele M.

Publication type:

Article

Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux.

Published in:

Nature Medicine, 2014, v. 20, n. 2, p. 152, doi. 10.1038/nm.3458

By:

Lee, Richard E;
Hurdle, Julian G;
Liu, Jiuyu;
Bruhn, David F;
Matt, Tanja;
Scherman, Michael S;
Vaddady, Pavan K;
Zheng, Zhong;
Qi, Jianjun;
Akbergenov, Rashid;
Das, Sourav;
Madhura, Dora B;
Rathi, Chetan;
Trivedi, Ashit;
Villellas, Cristina;
Lee, Robin B;
Rakesh;
Waidyarachchi, Samanthi L;
Sun, Dianqing;
McNeil, Michael R

Publication type:

Article

Pentacyclic Nitrofurans with <i>In Vivo</i> Efficacy and Activity against Nonreplicating <i>Mycobacterium tuberculosis</i>.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0087909

By:

Rakesh;
Bruhn, David F.;
Scherman, Michael S.;
Woolhiser, Lisa K.;
Madhura, Dora B.;
Maddox, Marcus M.;
Singh, Aman P.;
Lee, Robin B.;
Hurdle, Julian G.;
McNeil, Michael R.;
Lenaerts, Anne J.;
Meibohm, Bernd;
Lee, Richard E.

Publication type:

Article

Effectiveness of the Thermal Stimulation for Deep Geothermal Reservoirs.

Published in:

Geophysical Research Abstracts, 2018, v. 20, p. 7128

By:

Doonechaly, Nima Gholizadeh;
Bruhn, David F.

Publication type:

Article

Australian Marine and Terrestrial Streptomyces -Derived Surugamides, and Synthetic Analogs, and Their Ability to Inhibit Dirofilaria immitis (Heartworm) Motility.

Published in:

Marine Drugs, 2024, v. 22, n. 7, p. 312, doi. 10.3390/md22070312

By:

Wu, Taizong;
Hussein, Waleed M.;
Samarasekera, Kaumadi;
Zhu, Yuxuan;
Khalil, Zeinab G.;
Jin, Shengbin;
Bruhn, David F.;
Moreno, Yovany;
Salim, Angela A.;
Capon, Robert J.

Publication type:

Article

Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models.

Published in:

2017

By:

Robertson, Gregory T.;
Scherman, Michael S.;
Bruhn, David F.;
Liu, Jiuyu;
Hastings, Courtney;
McNeil, Michael R.;
Butler, Michelle M.;
Bowlin, Terry L.;
Lee, Robin B.;
Lee, Richard E.;
Lenaerts, Anne J.

Publication type:

journal article

Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes.

Published in:

2016

By:

Bruhn, David F.;
Wyllie, Susan;
Rodríguez-Cortés, Adaris;
Carrillo, Angela K.;
Rakesh;
Kiplin Guy, R.;
Fairlamb, Alan H.;
Lee, Richard E.;
Guy, R Kiplin

Publication type:

journal article

In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis Antibiotics.

Published in:

Scientific Reports, 2015, p. 13985, doi. 10.1038/srep13985

By:

Bruhn, David F.;
Scherman, Michael S.;
Liu, Jiuyu;
Scherbakov, Dimitri;
Meibohm, Bernd;
Böttger, Erik C.;
Lenaerts, Anne J.;
Lee, Richard E.

Publication type:

Article