Works by Bruce D. Trapp

Results: 95

Is Axonal Degeneration a Key Early Event in Parkinson's Disease?

Published in:

2016

By:

Kurowska, Zuzanna;
Kordower, Jeffrey H.;
Stoessl, A. Jon;
Burke, Robert E.;
Brundin, Patrik;
Zhenyu Yue;
Brady, Scott T.;
Milbrandt, Jeffrey;
Trapp, Bruce D.;
Sherer, Todd B.;
Medicetty, Satish

Publication type:

Proceeding

Cuprizone does not induce CNS demyelination in nonhuman primates.

Published in:

Annals of Clinical & Translational Neurology, 2015, v. 2, n. 2, p. 208, doi. 10.1002/acn3.159

By:

Chen, Zhihong;
Chen, Jacqueline T.;
Johnson, Matthew;
Gossman, Zachary C.;
Hendrickson, Megan;
Sakaie, Ken;
Martinez‐Rubio, Clarissa;
Gale, John T.;
Trapp, Bruce D.

Publication type:

Article

Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.918041

By:

Kihara, Yasuyuki;
Zhu, Yunjiao;
Jonnalagadda, Deepa;
Romanow, William;
Palmer, Carter;
Siddoway, Benjamin;
Rivera, Richard;
Dutta, Ranjan;
Trapp, Bruce D.;
Chun, Jerold

Publication type:

Article

Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation.

Published in:

Nature Medicine, 2005, v. 11, n. 9, p. 966, doi. 10.1038/nm1279

By:

Back, Stephen A.;
Tuohy, Therese M. F.;
Hanqin Chen;
Wallingford, Nicholas;
Craig, Andrew;
Struve, Jaime;
Ning Ling Luo;
Banine, Fatima;
Ying Liu;
Ansi Chang;
Trapp, Bruce D.;
Bebo Jr., Bruce F.;
Rao, Mahendra S.;
Sherman, Larry S.

Publication type:

Article

Cellular and Subcellular Distribution of 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase and Its mRNA in the Rat Central Nervous System.

Published in:

Journal of Neurochemistry, 1988, v. 51, n. 3, p. 859, doi. 10.1111/j.1471-4159.1988.tb01822.x

By:

Trapp, Bruce D.;
Bernier, Lise;
Andrews, S. Brian;
Colman, David R.

Publication type:

Article

Myelin-Associated Glycoprotein and Related Glycoconjugates in Developing Cat Peripheral Nerve: A Correlative Biochemical and Morphometric Study.

Published in:

Journal of Neurochemistry, 1987, v. 49, n. 6, p. 1853, doi. 10.1111/j.1471-4159.1987.tb02447.x

By:

Willison, Hugh J.;
Ilyas, Amjad I.;
O'Shannessy, Daniel J.;
Pulley, Mike;
D. Trapp,, Bruce;
Quarles, Richard H.

Publication type:

Article

Myelin-Associated Glycoprotein and Other Proteins in Trembler Mice.

Published in:

Journal of Neurochemistry, 1985, v. 44, n. 3, p. 793, doi. 10.1111/j.1471-4159.1985.tb12885.x

By:

Inuzuka, Takashi;
Quarles, Richard H.;
Heath, John;
Trapp, Bruce D.

Publication type:

Article

LOCALIZATION OF MYELIN-ASSOCIATED GLYCOPROTEIN.

Published in:

Journal of Neurochemistry, 1984, v. 43, n. 6, p. 1773, doi. 10.1111/j.1471-4159.1984.tb06110.x

By:

Quarles, Richard H.;
Trapp, Bruce D.

Publication type:

Article

Ultrastructural Localization of P2 Protein in Actively Myelinating Rat Schwann Cells.

Published in:

Journal of Neurochemistry, 1984, v. 43, n. 4, p. 944, doi. 10.1111/j.1471-4159.1984.tb12828.x

By:

Trapp, Bruce D.;
Dubois-Dalcq, Monique;
Quarles, Richard H.

Publication type:

Article

P2 Protein in Oligodendrocytes and Myelin of the Rabbit Central Nervous System.

Published in:

Journal of Neurochemistry, 1983, v. 40, n. 1, p. 47, doi. 10.1111/j.1471-4159.1983.tb12651.x

By:

Trapp, Bruce D.;
Itoyama, Yasuto;
MacIntosh, Tracy D.;
Quarles, Richard H.

Publication type:

Article

Biochemical Characterization of Myelin Isolated from the Central Nervous System of Xenopus Tadpoles.

Published in:

Journal of Neurochemistry, 1980, v. 34, n. 5, p. 1241, doi. 10.1111/j.1471-4159.1980.tb09965.x

By:

Trapp, Bruce D.;
McIntyre, Laurence J.;
Quarles, Richard H.;
Nonaka, Genïchro;
Moser, Ann;
Maser, Hugo W.;
Webster, Henry de F.

Publication type:

Article

Evolution of a neuroprotective function of central nervous system myelin.

Published in:

Journal of Cell Biology, 2006, v. 172, n. 3, p. 469, doi. 10.1083/jcb.200509174

By:

Yin, Xinghua;
Baek, Rena C.;
Kirschner, Daniel A.;
Peterson, Alan;
Fujii, Yasuhisa;
Nave, Klaus-Armin;
Macklin, Wendy B.;
Trapp, Bruce D.

Publication type:

Article

Lessons from Jack Griffin and the 'pathogenesis of peripheral nerve disease'.

Published in:

Journal of the Peripheral Nervous System, 2012, v. 17, p. 20, doi. 10.1111/j.1529-8027.2012.00426.x

By:

Trapp, Bruce D.

Publication type:

Article

Neuronal hibernation following hippocampal demyelination.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01130-9

By:

Baltan, Selva;
Jawaid, Safdar S.;
Chomyk, Anthony M.;
Kidd, Grahame J.;
Chen, Jacqueline;
Battapady, Harsha D.;
Chan, Ricky;
Dutta, Ranjan;
Trapp, Bruce D.

Publication type:

Article

Demyelination induced by intraneural injection of human antimyelin-associated glycoprotein antibodies.

Published in:

Muscle & Nerve, 1988, v. 11, n. 11, p. 1169, doi. 10.1002/mus.880111111

By:

Willison, Hugh J.;
Trapp, Bruce D.;
Bacher, John D.;
Dalakas, Marinos C.;
Griffin, John W.;
Quarles, Richard H.

Publication type:

Article

Dysmyelinated Lower Motor Neurons Retract and Regenerate Dysfunctional Synaptic Terminals.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 15, p. 3890, doi. 10.1523/JNEUROSCI.4617-03.2004

By:

Xinghua Yin;
Kidd, Grahame J.;
Pioro, Erik P.;
McDonough, Jennifer;
Dutta, Ranjan;
Feltri, M. Laura;
Wrabetz, Lawrence;
Messing, Albee;
Wyatt, Ryan M.;
Balice-Gordon, Rita J.;
Trapp, Bruce D.

Publication type:

Article

Dysmyelination in transgenic mice containing JC virus early region.

Published in:

Annals of Neurology, 1988, v. 23, n. 1, p. 38, doi. 10.1002/ana.410230108

By:

Trapp, Bruce D.;
Small, Judy A.;
Pulley, Michael;
Khoury, George;
Scangos, George A.

Publication type:

Article

Thymosin β4 is a shared antigen between lymphoid cells and oligodendrocytes of normal human brain.

Published in:

Annals of Neurology, 1986, v. 19, n. 4, p. 349, doi. 10.1002/ana.410190407

By:

Dalakas, Marinos C.;
Trapp, Bruce D.

Publication type:

Article

A quantitation of myelin-associated glycoprotein and myelin basic protein loss in different demyelinating disease.

Published in:

Annals of Neurology, 1985, v. 18, n. 3, p. 324, doi. 10.1002/ana.410180309

By:

Gendelman, Howard E.;
Pezeshkpour, Gholam H.;
Pressman, Norman J.;
Wolinsky, Jerry S.;
Quarles, Richard H.;
Dobersen, Michael J.;
Trapp, Bruce D.;
Kitt, Cheryl A.;
Aksamit, Allen;
Johnson, Richard T.

Publication type:

Article

Schwann cell remyelination of demyelinated axons in spinal cord multiple sclerosis lesions.

Published in:

Annals of Neurology, 1983, v. 14, n. 3, p. 339, doi. 10.1002/ana.410140313

By:

Itoyama, Yasuto;
Webster, Henry DeF.;
Richardson, Edward P.;
Trapp, Bruce D.

Publication type:

Article

Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves.

Published in:

FASEB Journal, 2008, v. 22, n. 8, p. 2970, doi. 10.1096/fj.08-106666

By:

Xiangyou Hu;
Wanxia He;
Diaconu, Claudiu;
Xiaoying Tang;
Kidd, Grahame J.;
Macklin, Wendy B.;
Trapp, Bruce D.;
Riqiang Yan

Publication type:

Article

Neurogenesis in the chronic lesions of multiple sclerosis.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A65

By:

Chang, Ansi;
Smith, Maria C.;
Xinghua Yin;
Staugaitis, Susan M.;
Trapp, Bruce D.

Publication type:

Article

A stem cell source for myelination in the adult brain.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A65

By:

Staugaitis, Susan M.;
Chang, Ansi;
Smith, Maria C.;
Chuanshen Wu;
Agamanolis, Dimitri;
Trapp, Bruce D.

Publication type:

Article

Sensitivity of T1/T2-weighted ratio in detection of cortical demyelination is similar to magnetization transfer ratio using post-mortem MRI.

Published in:

Multiple Sclerosis Journal, 2022, v. 28, n. 2, p. 198, doi. 10.1177/13524585211014760

By:

Zheng, Yufan;
Dudman, Jessica;
Chen, Jacqueline T;
Mahajan, Kedar R;
Herman, Danielle;
Fox, Robert J;
Ontaneda, Daniel;
Trapp, Bruce D;
Nakamura, Kunio

Publication type:

Article

Juxtacortical susceptibility changes in progressive multifocal leukoencephalopathy at the gray–white matter junction correlates with iron-enriched macrophages.

Published in:

Multiple Sclerosis Journal, 2021, v. 27, n. 14, p. 2159, doi. 10.1177/1352458521999651

By:

Mahajan, Kedar R;
Amin, Moein;
Poturalski, Matthew;
Lee, Jonathan;
Herman, Danielle;
Zheng, Yufan;
Androjna, Caroline;
Howell, Mark;
Fox, Robert J;
Trapp, Bruce D;
Jones, Stephen E;
Nakamura, Kunio;
Ontaneda, Daniel

Publication type:

Article

Brain fibrinogen deposition plays a key role in MS pathophysiology – Yes.

Published in:

Multiple Sclerosis Journal, 2019, v. 25, n. 11, p. 1434, doi. 10.1177/1352458519852723

By:

Davalos, Dimitrios;
Mahajan, Kedar R;
Trapp, Bruce D

Publication type:

Article

The role of the thalamus and hippocampus in episodic memory performance in patients with multiple sclerosis.

Published in:

Multiple Sclerosis Journal, 2019, v. 25, n. 4, p. 574, doi. 10.1177/1352458518760716

By:

Koenig, Katherine A.;
Rao, Stephen M.;
Lowe, Mark J.;
Lin, Jian;
Sakaie, Ken E.;
Stone, Lael;
Bermel, Robert A.;
Trapp, Bruce D.;
Phillips, Micheal D.

Publication type:

Article

Much, if not all, of the cortical damage in MS can be attributed to the microglial cell – No.

Published in:

Multiple Sclerosis Journal, 2018, v. 24, n. 7, p. 897, doi. 10.1177/1352458517743094

By:

Dutta, Ranjan;
Trapp, Bruce D.

Publication type:

Article

The relationship between cognitive function and high-resolution diffusion tensor MRI of the cingulum bundle in multiple sclerosis.

Published in:

Multiple Sclerosis Journal, 2015, v. 21, n. 14, p. 1794, doi. 10.1177/1352458515576983

By:

Koenig, Katherine A.;
Sakaie, Ken E.;
Lowe, Mark J.;
Jian Lin;
Stone, Lael;
Bermel, Robert A.;
Beall, Erik B.;
Rao, Stephen M.;
Trapp, Bruce D.;
Phillips, Micheal D.

Publication type:

Article

Demyelination in the central nervous system mediated by an anti-oligodendrocyte antibody.

Published in:

Journal of Neuroscience Research, 1998, v. 54, n. 2, p. 158, doi. 10.1002/(SICI)1097-4547(19981015)54:2<158::AID-JNR4>3.0.CO;2-D

By:

Zhou, Lixin;
Trapp, Bruce D.;
Miller, Robert H.

Publication type:

Article

Reversible Loss of Hippocampal Function in a Mouse Model of Demyelination/Remyelination.

Published in:

Frontiers in Cellular Neuroscience, 2020, v. 13, p. 1, doi. 10.3389/fncel.2019.00588

By:

Das, Aniruddha;
Bastian, Chinthasagar;
Trestan, Lexie;
Suh, Jason;
Dey, Tanujit;
Trapp, Bruce D.;
Baltan, Selva;
Dana, Hod

Publication type:

Article

p38γ MAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions.

Published in:

Brain: A Journal of Neurology, 2024, v. 147, n. 5, p. 1871, doi. 10.1093/brain/awad421

By:

Marziali, Leandro N;
Hwang, Yoonchan;
Palmisano, Marilena;
Cuenda, Ana;
Sim, Fraser J;
Gonzalez, Alberto;
Volsko, Christina;
Dutta, Ranjan;
Trapp, Bruce D;
Wrabetz, Lawrence;
Feltri, Maria L

Publication type:

Article

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis.

Published in:

Brain: A Journal of Neurology, 2011, v. 134, n. 7, p. 1901, doi. 10.1093/brain/awr110

By:

Zambonin, Jessica L.;
Zhao, Chao;
Ohno, Nobuhiko;
Campbell, Graham R.;
Engeham, Sarah;
Ziabreva, Iryna;
Schwarz, Nadine;
Lee, Sok Ee;
Frischer, Josa M.;
Turnbull, Doug M.;
Trapp, Bruce D.;
Lassmann, Hans;
Franklin, Robin J. M.;
Mahad, Don J.

Publication type:

Article

Neurogenesis in the chronic lesions of multiple sclerosis.

Published in:

Brain: A Journal of Neurology, 2008, v. 131, n. 9, p. 2366, doi. 10.1093/brain/awn157

By:

Ansi Chang;
Maria C. Smith;
Xinghua Yin;
Robert J. Fox;
Susan M. Staugaitis;
Bruce D. Trapp

Publication type:

Article

Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 34, p. 11706, doi. 10.1523/JNEUROSCI.0730-12.2012

By:

Zhihong Chen;
Jalabi, Walid;
Shpargel, Karl B.;
Farabaugh, Kenneth T.;
Dutta, Ranjan;
Xinghua Yin;
Kidd, Grahame J.;
Bergmann, Cornelia C.;
Stohlman, Stephen A.;
Trapp, Bruce D.

Publication type:

Article

NEURODEGENERATION: THE PATHOLOGIC EVIDENCE.

Published in:

Johns Hopkins Advanced Studies in Medicine, 2009, v. 9, n. 2, p. 37

By:

Trapp, Bruce D.

Publication type:

Article

Intrinsic and Extrinsic Mechanisms of Thalamic Pathology in Multiple Sclerosis.

Published in:

2020

By:

Mahajan, Kedar R.;
Nakamura, Kunio;
Cohen, Jeffrey A.;
Trapp, Bruce D.;
Ontaneda, Daniel

Publication type:

journal article

T1-/T2-weighted ratio differs in demyelinated cortex in multiple sclerosis.

Published in:

2017

By:

Nakamura, Kunio;
Chen, Jacqueline T.;
Ontaneda, Daniel;
Fox, Robert J.;
Trapp, Bruce D.

Publication type:

journal article

GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system.

Published in:

Scientific Reports, 2017, p. 42257, doi. 10.1038/srep42257

By:

Yoshimura, Takeshi;
Hayashi, Akiko;
Handa-Narumi, Mai;
Yagi, Hirokazu;
Ohno, Nobuhiko;
Koike, Takako;
Yamaguchi, Yoshihide;
Uchimura, Kenji;
Kadomatsu, Kenji;
Sedzik, Jan;
Kitamura, Kunio;
Kato, Koichi;
Trapp, Bruce D.;
Baba, Hiroko;
Ikenaka, Kazuhiro

Publication type:

Article

Epigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains.

Published in:

Nature Neuroscience, 2014, v. 17, n. 1, p. 121, doi. 10.1038/nn.3588

By:

Huynh, Jimmy L;
Garg, Paras;
Thin, Tin Htwe;
Yoo, Seungyeul;
Dutta, Ranjan;
Trapp, Bruce D;
Haroutunian, Vahram;
Zhu, Jun;
Donovan, Michael J;
Sharp, Andrew J;
Casaccia, Patrizia

Publication type:

Article

Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells.

Published in:

Nature Neuroscience, 2013, v. 16, n. 10, p. 1401, doi. 10.1038/nn.3505

By:

Kang, Zizhen;
Wang, Chenhui;
Zepp, Jarod;
Wu, Ling;
Sun, Kevin;
Zhao, Junjie;
Chandrasekharan, Unni;
DiCorleto, Paul E;
Trapp, Bruce D;
Ransohoff, Richard M;
Li, Xiaoxia

Publication type:

Article

The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination.

Published in:

Nature Neuroscience, 2009, v. 12, n. 11, p. 1398, doi. 10.1038/nn.2410

By:

Ying Chen;
Heng Wu;
Shuzong Wang;
Koito, Hisami;
Jianrong Li;
Feng Ye;
Hoang, Jenny;
Escobar, Sabine S.;
Gow, Alexander;
Arnett, Heather A.;
Trapp, Bruce D.;
Karandikar, Nitin J.;
Hsieh, Jenny;
Lu, Q. Richard

Publication type:

Article

Bace1 modulates myelination in the central and peripheral nervous system.

Published in:

Nature Neuroscience, 2006, v. 9, n. 12, p. 1520, doi. 10.1038/nn1797

By:

Xiangyou Hu;
Hicks, Caitlin W.;
Wanxia He;
Wong, Philip;
Macklin, Wendy B.;
Trapp, Bruce D.;
Riqiang Yan

Publication type:

Article

Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors.

Published in:

Annals of Neurology, 2013, v. 73, n. 5, p. 637, doi. 10.1002/ana.23860

By:

Dutta, Ranjan;
Chomyk, Anthony M.;
Chang, Ansi;
Ribaudo, Michael V.;
Deckard, Sadie A.;
Doud, Mary K.;
Edberg, Dale D.;
Bai, Brian;
Li, Michael;
Baranzini, Sergio E.;
Fox, Robert J.;
Staugaitis, Susan M.;
Macklin, Wendy B.;
Trapp, Bruce D.

Publication type:

Article

Cortical remyelination: A new target for repair therapies in multiple sclerosis.

Published in:

Annals of Neurology, 2012, v. 72, n. 6, p. 918, doi. 10.1002/ana.23693

By:

Chang, Ansi;
Staugaitis, Susan M.;
Dutta, Ranjan;
Batt, Courtney E.;
Easley, Kathryn E.;
Chomyk, Anthony M.;
Yong, V. Wee;
Fox, Robert J.;
Kidd, Grahame J.;
Trapp, Bruce D.

Publication type:

Article

Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients.

Published in:

Annals of Neurology, 2011, v. 69, n. 3, p. 445, doi. 10.1002/ana.22337

By:

Dutta, Ranjan;
Chang, Ansi;
Doud, Mary K.;
Kidd, Grahame J.;
Ribaudo, Michael V.;
Young, Elizabeth A.;
Fox, Robert J.;
Staugaitis, Susan M.;
Trapp, Bruce D.

Publication type:

Article

Glutamate receptors on myelinated spinal cord axons: II. AMPA and GluR5 receptors.

Published in:

Annals of Neurology, 2009, v. 65, n. 2, p. 160, doi. 10.1002/ana.21539

By:

Ouardouz, Mohamed;
Coderre, Elaine;
Zamponi, Gerald W.;
Hameed, Shameed;
Yin, Xinghua;
Trapp, Bruce D.;
Stys, Peter K.

Publication type:

Article

Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors.

Published in:

Annals of Neurology, 2009, v. 65, n. 2, p. 151, doi. 10.1002/ana.21533

By:

Ouardouz, Mohamed;
Coderre, Elaine;
Basak, Ajoy;
Chen, Andrew;
Zamponi, Gerald W.;
Hameed, Shameed;
Rehak, Renata;
Yin, Xinghua;
Trapp, Bruce D.;
Stys, Peter K.

Publication type:

Article

Imaging correlates of decreased axonal Na+/K+ ATPase in chronic multiple sclerosis lesions.

Published in:

2008

By:

Young EA;
Fowler CD;
Kidd GJ;
Chang A;
Rudick R;
Fisher E;
Trapp BD;
Young, Elizabeth A;
Fowler, Christie D;
Kidd, Grahame J;
Chang, Ansi;
Rudick, Richard;
Fisher, Elizabeth;
Trapp, Bruce D

Publication type:

journal article

Imaging correlates of decreased axonal Na+/K+ ATPase in chronic multiple sclerosis lesions.

Published in:

Annals of Neurology, 2008, v. 63, n. 4, p. 428, doi. 10.1002/ana.21381

By:

Young, Elizabeth A.;
Fowler, Christie D.;
Kidd, Grahame J.;
Chang, Ansi;
Rudick, Richard;
Fisher, Elizabeth;
Trapp, Bruce D.

Publication type:

Article