Works by Brown, Kristy A.

Results: 64

SREBP1-Dependent Metabolism as a Potential Target for Breast Cancer Risk Reduction.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1664, doi. 10.3390/cancers17101664

By:

Hajirahimkhan, Atieh;
Brown, Kristy A.;
Clare, Susan E.;
Khan, Seema Ahsan

Publication type:

Article

GOTreePlus: an interactive gene ontology browser.

Published in:

Bioinformatics, 2008, v. 24, n. 7, p. 1026, doi. 10.1093/bioinformatics/btn068

By:

Bongshin Lee;
Kristy Brown;
Yetrib Hathout;
Jinwook Seo

Publication type:

Article

No effect of unacylated ghrelin administration on subcutaneous PC3 xenograft growth or metabolic parameters in a Rag1-/- mouse model of metabolic dysfunction.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0198495

By:

Maugham, Michelle L.;
Seim, Inge;
Thomas, Patrick B.;
Crisp, Gabrielle J.;
Shah, Esha T.;
Herington, Adrian C.;
Brown, Kristy A.;
Gregory, Laura S.;
Nelson, Colleen C.;
Jeffery, Penny L.;
Chopin, Lisa K.

Publication type:

Article

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.

Published in:

Nature Medicine, 2007, v. 13, n. 10, p. 1203, doi. 10.1038/nm1636

By:

Palomero, Teresa;
Sulis, Maria Luisa;
Cortina, Maria;
Real, Pedro J.;
Barnes, Kelly;
Ciofani, Maria;
Caparros, Esther;
Buteau, Jean;
Brown, Kristy;
Perkins, Sherrie L.;
Bhagat, Govind;
Agarwal, Archana M.;
Basso, Giuseppe;
Castillo, Mireia;
Nagase, Satoru;
Cordon-Cardo, Carlos;
Parsons, Ramon;
Zúñiga-Pflücker, Juan Carlos;
Dominguez, Maria;
Ferrando, Adolfo A.

Publication type:

Article

Quantitative Proteomics Reveals an Altered Cystic Fibrosis In Vitro Bronchial Epithelial Secretome.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2015, v. 53, n. 1, p. 22, doi. 10.1165/rcmb.2014-0256RC

By:

Peters-Hall, Jennifer R.;
Brown, Kristy J.;
Pillai, Dinesh K.;
Tomney, Amarel;
Garvin, Lindsay M.;
Xiaofang Wu;
Rose, Mary C.

Publication type:

Article

Directional Secretomes Reflect Polarity-Specific Functions in an In Vitro Model of Human Bronchial Epithelium.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2014, v. 50, n. 2, p. 292, doi. 10.1165/rcmb.2013-0188OC

By:

Pillai, Dinesh K.;
Sankoorikal, Binu-John V.;
Johnson, Eric;
Seneviratne, Angelo N.;
Zurko, Jessica;
Brown, Kristy J.;
Hathout, Yetrib;
Rose, Mary C.

Publication type:

Article

Cyclooxygenase-2 and its role in ovulation: a 2004 account.

Published in:

Human Reproduction Update, 2004, v. 10, n. 5, p. 373, doi. 10.1093/humupd/dmh032

By:

Jean Sirois;
Khampoune Sayasith;
Kristy A. Brown;
Angelika E. Stock;
Nadine Bouchard;
Monique Doré

Publication type:

Article

IL-10 suppresses TNF-α-induced expression of human aromatase gene in mammary adipose tissue.

Published in:

FASEB Journal, 2018, v. 32, n. 6, p. 3361, doi. 10.1096/fj.201700938RRR

By:

Martínez-Chacón, Gabriela;
Brown, Kristy A.;
Docanto, Maria M.;
Kumar, Himanshu;
Salminen, Seppo;
Saarinen, Niina;
Mäkelä, Sari

Publication type:

Article

Nontypeable Haemophilus influenzae lysates increase heterogeneous nuclear ribonucleoprotein secretion and exosome release in human middle-ear epithelial cells.

Published in:

FASEB Journal, 2018, v. 32, n. 4, p. 1855, doi. 10.1096/fj.201700248RR

By:

Val, Stéphanie;
Krueger, Anna;
Poley, Marian;
Cohen, Ariella;
Brown, Kristy;
Panigrahi, Aswini;
Preciado, Diego

Publication type:

Article

Asymptomatic African Americans with high‐risk APOL1 genotypes have reduced urinary angiogenesis‐promoting cytokines.

Published in:

FASEB Journal, 2013, v. 27, p. lb474, doi. 10.1096/fasebj.27.1_supplement.lb474

By:

Gutierrez, Jean Lorraine;
Many, Gina;
Panchapakesan, Karuna;
Brown, Kristy J;
Hathout, Yetrib;
Marathi, Ramya;
Devaney, Joseph;
Hoffman, Eric P

Publication type:

Article

Calcium triggers assembly of ESCRT proteins at the cell membrane.

Published in:

FASEB Journal, 2013, v. 27, p. lb130, doi. 10.1096/fasebj.27.1_supplement.lb130

By:

Scheffer, Luana Lea;
Sharma, Nimisha;
Medikayala, Sushma;
Brown, Kristy;
Jaiswal, Jyoti K

Publication type:

Article

Identification of Gene‐Therapy Responsive Blood Biomarkers in mdx Mouse Model.

Published in:

JCSM Rapid Communications, 2024, v. 7, n. 2, p. 187, doi. 10.1002/rco2.112

By:

Johansson, Camilla;
Boehler, Jessica F.;
Brown, Kristy J.;
Koeks, Zaïda;
Schrama, Esther J.;
van de Velde, Nienke;
Verschuuren, Jan J. G. M.;
Niks, Erik H.;
Spitali, Pietro;
Al‐Khalili Szigyarto, Cristina

Publication type:

Article

The benefits of adding metformin to tamoxifen to protect the endometrium—A randomized placebo‐controlled trial.

Published in:

Clinical Endocrinology, 2018, v. 89, n. 5, p. 605, doi. 10.1111/cen.13830

By:

Davis, Susan R.;
Robinson, Penelope J.;
Jane, Fiona;
White, Shane;
Brown, Kristy A.;
Piessens, Sofie;
Edwards, Andrew;
McNeilage, Jane;
Woinarski, Jillian;
Chipman, Mitchell;
Bell, Robin J.

Publication type:

Article

Neurofilament light polypeptide gene N98S mutation in mice leads to neurofilament network abnormalities and a Charcot-Marie-Tooth Type 2E phenotype.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 8, p. 2163, doi. 10.1093/hmg/ddu736

By:

Adebola, Adijat A.;
Di Castri, Theo;
Chui-Zhen He;
Salvatierra, Laura A.;
Jian Zhao;
Brown, Kristy;
Lin, Chyuan-Sheng;
Worman, Howard J.;
Liem, Ronald K. H.

Publication type:

Article

Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 24, p. 6458, doi. 10.1093/hmg/ddu366

By:

Hathout, Yetrib;
Marathi, Ramya L.;
Rayavarapu, Sree;
Zhang, Aiping;
Brown, Kristy J.;
Seol, Haeri;
Gordish-Dressman, Heather;
Cirak, Sebahattin;
Bello, Luca;
Nagaraju, Kanneboyina;
Partridge, Terry;
Hoffman, Eric P.;
Takeda, Shin'ichi;
Mah, Jean K.;
Henricson, Erik;
McDonald, Craig

Publication type:

Article

Pleomorphism of Legionella Pneumophila.

Published in:

Ultrastructural Pathology, 1984, v. 6, n. 2/3, p. 117, doi. 10.3109/01913128409018566

By:

Katz, Sheila Moriber;
Hashemi, Shahab;
Brown, Kristy R.;
Habib, William A.;
Hammel, Jay M.

Publication type:

Article

Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy.

Published in:

Science Translational Medicine, 2023, v. 15, n. 677, p. 1, doi. 10.1126/scitranslmed.abo1815

By:

Birch, Sharla M.;
Lawlor, Michael W.;
Conlon, Thomas J.;
Guo, Lee-Jae;
Crudele, Julie M.;
Hawkins, Eleanor C.;
Nghiem, Peter P.;
Ahn, Mihye;
Meng, Hui;
Beatka, Margaret J.;
Fickau, Brittany A.;
Prieto, Juan C.;
Styner, Martin A.;
Struharik, Michael J.;
Shanks, Courtney;
Brown, Kristy J.;
Golebiowski, Diane;
Bettis, Amanda K.;
Balog-Alvarez, Cynthia J.;
Clement, Nathalie

Publication type:

Article

Doublecortin (Dcx) Family Proteins Regulate Filamentous Actin Structure in Developing Neurons.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 2, p. 709, doi. 10.1523/JNEUROSCI.4603-12.2013

By:

Xiaoqin Fu;
Brown, Kristy J.;
Chan Choo Yap;
Winckler, Bettina;
Jaiswal, Jyoti K.;
Liu, Judy S.

Publication type:

Article

Adrenal Steroids and Resistance to Hormonal Blockade of Prostate and Breast Cancer.

Published in:

Endocrinology, 2023, v. 164, n. 3, p. 1, doi. 10.1210/endocr/bqac218

By:

Michael, Patrick;
Roversi, Gustavo;
Brown, Kristy;
Sharifi, Nima

Publication type:

Article

Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children.

Published in:

Scientific Reports, 2016, p. 31727, doi. 10.1038/srep31727

By:

Hathout, Yetrib;
Conklin, Laurie S.;
Seol, Haeri;
Gordish-Dressman, Heather;
Brown, Kristy J.;
Morgenroth, Lauren P.;
Nagaraju, Kanneboyina;
Heier, Christopher R.;
Damsker, Jesse M.;
van den Anker, John N.;
Henricson, Erik;
Clemens, Paula R.;
Mah, Jean K.;
McDonald, Craig;
Hoffman, Eric P.

Publication type:

Article

Facts and Perspectives: Implications of tumor glycolysis on immunotherapy response in triple negative breast cancer.

Published in:

Frontiers in Oncology, 2023, v. 12, p. 1, doi. 10.3389/fonc.2022.1061789

By:

Schreier, Ashley;
Zappasodi, Roberta;
Serganova, Inna;
Brown, Kristy A.;
Demaria, Sandra;
Andreopoulou, Eleni

Publication type:

Article

Effect of endurance exercise on microRNAs in myositis skeletal muscle—A randomized controlled study.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0183292

By:

Boehler, Jessica F.;
Hogarth, Marshall W.;
Barberio, Matthew D.;
Novak, James S.;
Ghimbovschi, Svetlana;
Brown, Kristy J.;
Alemo Munters, Li;
Loell, Ingela;
Chen, Yi-Wen;
Gordish-Dressman, Heather;
Alexanderson, Helene;
Lundberg, Ingrid E.;
Nagaraju, Kanneboyina

Publication type:

Article

Abnormal neurofilament inclusions and segregations in dorsal root ganglia of a Charcot-Marie-Tooth type 2E mouse model.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0180038

By:

Zhao, Jian;
Brown, Kristy;
Liem, Ronald K. H.

Publication type:

Article

Update on Adipose Tissue and Cancer.

Published in:

Endocrine Reviews, 2023, v. 44, n. 6, p. 961, doi. 10.1210/endrev/bnad015

By:

Brown, Kristy A;
Scherer, Philipp E

Publication type:

Article

AMP‐activated protein kinase signaling regulated expression of urea cycle enzymes in response to changes in dietary protein intake.

Published in:

Journal of Inherited Metabolic Disease, 2019, v. 42, n. 6, p. 1088, doi. 10.1002/jimd.12133

By:

Heibel, Sandra K.;
McGuire, Peter J.;
Haskins, Nantaporn;
Majumdar, Himani D.;
Rayavarapu, Sree;
Nagaraju, Kanneboyina;
Hathout, Yetrib;
Brown, Kristy;
Tuchman, Mendel;
Caldovic, Ljubica

Publication type:

Article

Impact of Obesity on Mammary Gland Inflammation and Local Estrogen Production.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2014, v. 19, n. 2, p. 183, doi. 10.1007/s10911-014-9321-0

By:

Brown, Kristy

Publication type:

Article

4485 Silicone Implant Shells Increase the Rate of Proliferation of Patient-Derived BIA-ALCL Cells but Not Primary T Cells in an Engineered Biomimetic Breast Platform.

Published in:

2020

By:

Premaratne, Ishani;
Wright, Matthew;
Gadjiko, Mariam;
Lara, Daniel;
Samadi, Arash;
Ginter, Paula;
Inghirami, Giorgio;
Brown, Kristy;
Spector, Jason

Publication type:

Abstract

Mutations in the neurofilament light gene linked to Charcot-Marie-Tooth disease cause defects in transport.

Published in:

Journal of Neurochemistry, 2005, v. 93, n. 4, p. 861, doi. 10.1111/j.1471-4159.2005.03095.x

By:

Raü Pérez-Ollé;
López-Toledano, Miguel A.;
Goryunov, Dmitry;
Cabrera-Poch, Noemi;
Stefanis, Leonidas;
Brown, Kristy;
Liem, Ronald K. H.

Publication type:

Article

τ Regulation of Microtubule-Microtubule Spacing and Bundling.

Published in:

Journal of Neurochemistry, 1994, v. 63, n. 6, p. 2288, doi. 10.1046/j.1471-4159.1994.63062288.x

By:

Frappier, Thierry F.;
Georgieff, Irene S.;
Brown, Kristy;
Shelanski, Michael L.

Publication type:

Article

Propranolol-Mediated Attenuation of MMP-9 Excretion in Infants With Hemangiomas.

Published in:

JAMA Otolaryngology-Head & Neck Surgery, 2013, v. 139, n. 10, p. 1026, doi. 10.1001/jamaoto.2013.4773

By:

Thaivalappil, Silpa;
Bauman, Nancy;
Saieg, Amarel;
Movius, Elizabeth;
Brown, Kristy J.;
Preciado, Diego

Publication type:

Article

Menopause Is a Determinant of Breast Aromatase Expression and Its Associations With BMI, Inflammation, and Systemic Markers.

Published in:

2017

By:

Brown, Kristy A;
Iyengar, Neil M;
Zhou, Xi Kathy;
Gucalp, Ayca;
Subbaramaiah, Kotha;
Wang, Hanhan;
Giri, Dilip D;
Morrow, Monica;
Falcone, Domenick J;
Wendel, Nils K;
Winston, Lisle A;
Pollak, Michael;
Dierickx, Anneloor;
Hudis, Clifford A;
Dannenberg, Andrew J

Publication type:

journal article

Genomic basis of aromatase excess syndrome: recombination- and replication-mediated rearrangements leading to CYP19A1 overexpression.

Published in:

2013

By:

Fukami, Maki;
Tsuchiya, Takayoshi;
Vollbach, Heike;
Brown, Kristy A;
Abe, Shuji;
Ohtsu, Shigeyuki;
Wabitsch, Martin;
Burger, Henry;
Simpson, Evan R;
Umezawa, Akihiro;
Shihara, Daizou;
Nakabayashi, Kazuhiko;
Bulun, Serdar E;
Shozu, Makio;
Ogata, Tsutomu

Publication type:

journal article

Overexpression of Aromatase Associated With Loss of Heterozygosity of the STK11 Gene Accounts for Prepubertal Gynecomastia in Boys with Peutz-Jeghers Syndrome.

Published in:

2013

By:

Ham, Seungmin;
Meachem, Sarah J;
Choong, Catherine S;
Charles, Adrian K;
Baynam, Gareth S;
Jones, Timothy W;
Samarajeewa, Nirukshi U;
Simpson, Evan R;
Brown, Kristy A

Publication type:

Journal Article

The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer.

Published in:

Breast Cancer Research & Treatment, 2017, v. 161, n. 2, p. 213, doi. 10.1007/s10549-016-4050-2

By:

McNamara, Keely;
Oguro, Saki;
Omata, Fumiya;
Kikuchi, Kyoko;
Guestini, Fouzia;
Suzuki, Koyu;
Yang, Yang;
Abe, Eriko;
Hirakawa, Hisashi;
Brown, Kristy;
Takanori, Ishida;
Ohuchi, Noriaki;
Sasano, Hironobu

Publication type:

Article

Ghrelin and des-acyl ghrelin inhibit aromatase expression and activity in human adipose stromal cells: suppression of cAMP as a possible mechanism.

Published in:

2014

By:

Docanto, Maria;
Yang, Fangyuan;
Callaghan, Brid;
Au, CheukMan;
Ragavan, Rahini;
Wang, Xuyi;
Furness, John;
Andrews, Zane;
Brown, Kristy

Publication type:

Report

Androgenic pathways in the progression of triple-negative breast carcinoma: a comparison between aggressive and non-aggressive subtypes.

Published in:

Breast Cancer Research & Treatment, 2014, v. 145, n. 2, p. 281, doi. 10.1007/s10549-014-2942-6

By:

McNamara, Keely;
Yoda, Tomomi;
Nurani, Alif;
Shibahara, Yukiko;
Miki, Yasuhiro;
Wang, Lin;
Nakamura, Yasuhiro;
Suzuki, Koyu;
Yang, Yang;
Abe, Eriko;
Hirakawa, Hisashi;
Suzuki, Takashi;
Nemoto, Noriko;
Miyashita, Minoru;
Tamaki, Kentaro;
Ishida, Takanori;
Brown, Kristy;
Ohuchi, Noriaki;
Sasano, Hironobu

Publication type:

Article

Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase.

Published in:

2010

By:

Brown, Kristy;
Hunger, Nicole;
Docanto, Maria;
Simpson, Evan

Publication type:

Report

Characterisation of aromatase expression in the human adipocyte cell line SGBS.

Published in:

Breast Cancer Research & Treatment, 2008, v. 112, n. 3, p. 429, doi. 10.1007/s10549-007-9883-2

By:

McInnes, Kerry;
Brown, Kristy;
Knower, Kevin;
Chand, Ashwini;
Clyne, Colin;
Simpson, Evan

Publication type:

Article

Creation and characterization of an immortalized canine myoblast cell line: Myok9.

Published in:

Mammalian Genome, 2020, v. 31, n. 3/4, p. 95, doi. 10.1007/s00335-020-09833-5

By:

López, Sara Mata;
Balog-Alvarez, Cynthia;
Canessa, Emily H.;
Hathout, Yetrib;
Brown, Kristy J.;
Vitha, Stanislav;
Bettis, Amanda K.;
Boehler, Jessica;
Kornegay, Joe N.;
Nghiem, Peter P.

Publication type:

Article

Ghrelin and Breast Cancer: emerging Roles in Obesity, estrogen Regulation, and Cancer.

Published in:

Frontiers in Oncology, 2017, v. 6, p. 1, doi. 10.3389/fonc.2016.00265

By:

Au, CheukMan Cherie;
Furness, John B.;
Brown, Kristy A.

Publication type:

Article

Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes.

Published in:

Nature Communications, 2016, v. 7, n. 1, p. 10312, doi. 10.1038/ncomms10312

By:

Eng, George;
Lee, Benjamin W.;
Protas, Lev;
Gagliardi, Mark;
Brown, Kristy;
Kass, Robert S.;
Keller, Gordon;
Robinson, Richard B.;
Vunjak-Novakovic, Gordana

Publication type:

Article

Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair.

Published in:

Nature Communications, 2014, v. 5, n. 12, p. 5646, doi. 10.1038/ncomms6646

By:

Scheffer, Luana L.;
Sreetama, Sen Chandra;
Sharma, Nimisha;
Medikayala, Sushma;
Brown, Kristy J.;
Defour, Aurelia;
Jaiswal, Jyoti K.

Publication type:

Article

N-terminal titin fragment: a non-invasive, pharmacodynamic biomarker for microdystrophin efficacy.

Published in:

Skeletal Muscle, 2024, v. 14, n. 1, p. 1, doi. 10.1186/s13395-023-00334-y

By:

Boehler, Jessica F.;
Brown, Kristy J.;
Ricotti, Valeria;
Morris, Carl A.

Publication type:

Article

High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium.

Published in:

Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0592-1

By:

Huo, Cecilia W.;
Grace Chew;
Hill, Prue;
Dexing Huang;
Ingman, Wendy;
Hodson, Leigh;
Brown, Kristy A.;
Magenau, Astrid;
Allam, Amr H.;
McGhee, Ewan;
Timpson, Paul;
Henderson, Michael A.;
Thompson, Erik W.;
Britt, Kara

Publication type:

Article

High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium.

Published in:

2015

By:

Huo, Cecilia W;
Chew, Grace;
Hill, Prue;
Huang, Dexing;
Ingman, Wendy;
Hodson, Leigh;
Brown, Kristy A;
Magenau, Astrid;
Allam, Amr H;
McGhee, Ewan;
Timpson, Paul;
Henderson, Michael A;
Thompson, Erik W;
Britt, Kara

Publication type:

journal article

HIF-1α stimulates aromatase expression driven by prostaglandin E2 in breast adipose stroma.

Published in:

Breast Cancer Research, 2013, v. 15, n. 2, p. 1, doi. 10.1186/bcr3410

By:

Samarajeewa, Nirukshi U.;
Yang, Fangyuan;
Docanto, Maria M.;
Sakurai, Minako;
McNamara, Keely M.;
Sasano, Hironobu;
Fox, Stephen B.;
Simpson, Evan R.;
Brown, Kristy A.

Publication type:

Article

HIF-1α stimulates aromatase expression driven by prostaglandin E2 in breast adipose stroma.

Published in:

2013

By:

Samarajeewa, Nirukshi U;
Yang, Fangyuan;
Docanto, Maria M;
Sakurai, Minako;
McNamara, Keely M;
Sasano, Hironobu;
Fox, Stephen B;
Simpson, Evan R;
Brown, Kristy A

Publication type:

journal article

Cell cycle inhibition and retinoblastoma protein overexpression prevent Purkinje cell death in organotypic slice cultures.

Published in:

Developmental Neurobiology (19328451), 2007, v. 67, n. 6, p. 818, doi. 10.1002/dneu.20394

By:

Padmanabhan, Jaya;
Brown, Kristy;
Shelanski, Michael L.

Publication type:

Article

Dysregulated metabolism and the regulation of aromatase in breast adipose stromal cells in obesity and cancer.

Published in:

2012

By:

Samarajeewa, Nirukshi U.;
Fangyuan Yang;
Docanto, Maria;
Sakurai, Minako;
Sasano, Hironobu;
Simpson, Evan R.;
Brown, Kristy A.

Publication type:

Abstract

Proteomic Characterization of Middle Ear Fluid Confirms Neutrophil Extracellular Traps as a Predominant Innate Immune Response in Chronic Otitis Media.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0152865

By:

Val, Stephanie;
Poley, Marian;
Brown, Kristy;
Choi, Rachel;
Jeong, Stephanie;
Colberg-Poley, Annie;
Rose, Mary C.;
Panchapakesan, Karuna C.;
Devaney, Joe C.;
Perez-Losada, Marcos;
Preciado, Diego

Publication type:

Article