Works by Brown, Christine E.

Results: 39

Donor-derived CD19-targeted chimeric antigen receptor T cells in adult transplant recipients with relapsed/refractory acute lymphoblastic leukemia.
Published in:
Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00881-z
By:
- Aldoss, Ibrahim;
- Khaled, Samer K.;
- Wang, Yan;
- Wang, Xiuli;
- Palmer, Joycelynne;
- Clark, Mary C.;
- Wagner, Jamie R.;
- Paul, Jinny;
- Vyas, Vibhuti;
- Brown, Christine E.;
- Forman, Stephen J.
Publication type:
Article
Outsmarting trogocytosis to boost CAR NK/T cell therapy.
Published in:
Molecular Cancer, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12943-023-01894-9
By:
- Ramezani, Faezeh;
- Panahi Meymandi, Ahmad Reza;
- Akbari, Behnia;
- Tamtaji, Omid Reza;
- Mirzaei, Hamed;
- Brown, Christine E.;
- Mirzaei, Hamid Reza
Publication type:
Article
Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01850
By:
- Mirzaei, Hamid R.;
- Rodriguez, Analiz;
- Shepphird, Jennifer;
- Brown, Christine E.;
- Badie, Behnam
Publication type:
Article
Evaluation of the Immunomodulatory Effects of Radiation for Chimeric Antigen Receptor T Cell Therapy in Glioblastoma Multiforme.
Published in:
Cells (2073-4409), 2024, v. 13, n. 13, p. 1075, doi. 10.3390/cells13131075
By:
- Akhavan, David;
- Subham, Siddharth;
- Jeppson, John D.;
- Aguilar, Brenda;
- Wong, Robyn A.;
- Hibbard, Jonathan C.;
- Hui, Susanta;
- Wong, Jeffrey Y. C.;
- Forman, Stephen J.;
- Alizadeh, Darya;
- Brown, Christine E.
Publication type:
Article
Vitamin C, From Supplement to Treatment: A Re-Emerging Adjunct for Cancer Immunotherapy?
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.765906
By:
- Kouakanou, Léonce;
- Peters, Christian;
- Brown, Christine E.;
- Kabelitz, Dieter;
- Wang, Leo D.
Publication type:
Article
Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31340-1
By:
- Comba, Andrea;
- Faisal, Syed M.;
- Dunn, Patrick J.;
- Argento, Anna E.;
- Hollon, Todd C.;
- Al-Holou, Wajd N.;
- Varela, Maria Luisa;
- Zamler, Daniel B.;
- Quass, Gunnar L.;
- Apostolides, Pierre F.;
- Abel II, Clifford;
- Brown, Christine E.;
- Kish, Phillip E.;
- Kahana, Alon;
- Kleer, Celina G.;
- Motsch, Sebastien;
- Castro, Maria G.;
- Lowenstein, Pedro R.
Publication type:
Article
PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with <sup>89</sup>Zr-Oxine.
Published in:
Journal of Nuclear Medicine, 2018, v. 59, n. 10, p. 1531, doi. 10.2967/jnumed.117.206714
By:
- Weist, Michael R.;
- Starr, Renate;
- Aguilar, Brenda;
- Chea, Junie;
- Miles, Joshua K.;
- Poku, Erasmus;
- Gerdts, Ethan;
- Xin Yang;
- Priceman, Saul J.;
- Forman, Stephen J.;
- Colcher, David;
- Brown, Christine E.;
- Shively, John E.
Publication type:
Article
Targeting CEA in metastatic triple negative breast cancer with image-guided radiation followed by Fab-mediated chimeric antigen receptor (CAR) T-cell therapy.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1499471
By:
- Aniogo, Eric;
- Kujawski, Maciej;
- Awuah, Dennis;
- Cha, Seung E.;
- Espinosa, Ruby;
- Hui, Susanta;
- Ghimire, Hemendra;
- Yazaki, Paul J.;
- Brown, Christine E.;
- Wang, Xiuli;
- Shively, John E.
Publication type:
Article
Targeting Wnt signaling for improved glioma immunotherapy.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1342625
By:
- Gutova, Margarita;
- Hibbard, Jonathan C.;
- Ma, Eric;
- Natri, Heini M.;
- Adhikarla, Vikram;
- Chimge, Nyam-Osor;
- Runxiang Qiu;
- Cu Nguyen;
- Melendez, Elizabeth;
- Aguilar, Brenda;
- Starr, Renate;
- Yin, Holly;
- Rockne, Russel C.;
- Masaya Ono;
- Banovich, Nicholas E.;
- Yate-Ching Yuan;
- Brown, Christine E.;
- Kahn, Michael
Publication type:
Article
L1 Cell Adhesion Molecule-Specific Chimeric Antigen Receptor-Redirected Human T Cells Exhibit Specific and Efficient Antitumor Activity against Human Ovarian Cancer in Mice.
Published in:
PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146885
By:
- Hong, Hao;
- Brown, Christine E.;
- Ostberg, Julie R.;
- Priceman, Saul J.;
- Chang, Wen-Chung;
- Weng, Lihong;
- Lin, Paul;
- Wakabayashi, Mark T.;
- Jensen, Michael C.;
- Forman, Stephen J.
Publication type:
Article
Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma.
Published in:
Neuro-Oncology, 2022, v. 24, n. 8, p. 1318, doi. 10.1093/neuonc/noac024
By:
- Brown, Christine E;
- Rodriguez, Analiz;
- Palmer, Joycelynne;
- Ostberg, Julie R;
- Naranjo, Araceli;
- Wagner, Jamie R;
- Aguilar, Brenda;
- Starr, Renate;
- Weng, Lihong;
- Synold, Timothy W;
- Tran, Vivi;
- Wang, Shelley;
- Reik, Andreas;
- D'Apuzzo, Massimo;
- Ressler, Julie A;
- Zhou, Yuanyue;
- Mendel, Matthew;
- Gregory, Philip D;
- Holmes, Michael C;
- Tang, Winson W
Publication type:
Article
Significance of interleukin-13 receptor alpha 2–targeted glioblastoma therapy.
Published in:
Neuro-Oncology, 2014, v. 16, n. 10, p. 1304, doi. 10.1093/neuonc/nou045
By:
- Thaci, Bart;
- Brown, Christine E.;
- Binello, Emanuela;
- Werbaneth, Katherine;
- Sampath, Prakash;
- Sengupta, Sadhak
Publication type:
Article
Health inequity focus in pandemic preparedness and response plans.
Published in:
2022
By:
- Mujica, Oscar J.;
- Brown, Christine E.;
- Victora, Cesar G.;
- Goldblatt, Peter O.;
- Barbosa da Silva Jr., Jarbas
Publication type:
Editorial
Neural Stem Cell-Mediated Enzyme/Prodrug Therapy for Glioma: Preclinical Studies.
Published in:
Science Translational Medicine, 2013, v. 5, n. 184, p. 1, doi. 10.1126/scitranslmed.3005365
By:
- Aboody, Karen S.;
- Najbauer, Joseph;
- Metz, Marianne Z.;
- D'Apuzzo, Massimo;
- Gutova, Margarita;
- Annala, Alexander J.;
- Synold, Timothy W.;
- Couture, Larry A.;
- Blanchard, Suzette;
- Moats, Rex A.;
- Garcia, Elizabeth;
- Aramburo, Soraya;
- Valenzuela, Valerie V.;
- Frank, Richard T.;
- Barish, Michael E.;
- Brown, Christine E.;
- Kim, Seung U.;
- Badie, Behnam;
- Portnow, Jana
Publication type:
Article
Structural and practical identifiability of contrast transport models for DCE-MRI.
Published in:
PLoS Computational Biology, 2024, v. 20, n. 5, p. 1, doi. 10.1371/journal.pcbi.1012106
By:
- Conte, Martina;
- Woodall, Ryan T.;
- Gutova, Margarita;
- Chen, Bihong T.;
- Shiroishi, Mark S.;
- Brown, Christine E.;
- Munson, Jennifer M.;
- Rockne, Russell C.
Publication type:
Article
Chimeric Antigen Receptors With Mutated IgG4 Fc Spacer Avoid Fc Receptor Binding and Improve T Cell Persistence and Antitumor Efficacy.
Published in:
Molecular Therapy, 2015, v. 23, n. 4, p. 757, doi. 10.1038/mt.2014.208
By:
- Jonnalagadda, Mahesh;
- Mardiros, Armen;
- Urak, Ryan;
- Wang, Xiuli;
- Hoffman, Lauren J;
- Bernanke, Alyssa;
- Chang, Wen-Chung;
- Bretzlaff, William;
- Starr, Renate;
- Priceman, Saul;
- Ostberg, Julie R;
- Forman, Stephen J;
- Brown, Christine E
Publication type:
Article
CAR T cells for brain tumors: Lessons learned and road ahead.
Published in:
Immunological Reviews, 2019, v. 290, n. 1, p. 60, doi. 10.1111/imr.12773
By:
- Akhavan, David;
- Alizadeh, Darya;
- Wang, Dongrui;
- Weist, Michael R.;
- Shepphird, Jennifer K.;
- Brown, Christine E.
Publication type:
Article
Corrigendum: Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications.
Published in:
2019
By:
- Mirzaei, Hamid R.;
- Rodriguez, Analiz;
- Shepphird, Jennifer;
- Brown, Christine E.;
- Badie, Behnam
Publication type:
Correction Notice
Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma.
Published in:
Science Translational Medicine, 2020, v. 12, n. 533, p. 1, doi. 10.1126/scitranslmed.aaw2672
By:
- Wang, Dongrui;
- Starr, Renate;
- Chang, Wen-Chung;
- Aguilar, Brenda;
- Alizadeh, Darya;
- Wright, Sarah L.;
- Yang, Xin;
- Brito, Alfonso;
- Sarkissian, Aniee;
- Ostberg, Julie R.;
- Li, Li;
- Shi, Yanhong;
- Gutova, Margarita;
- Aboody, Karen;
- Badie, Behnam;
- Forman, Stephen J.;
- Barish, Michael E.;
- Brown, Christine E.
Publication type:
Article
Preclinical Evaluation of CAR T Cell Function: In Vitro and In Vivo Models.
Published in:
2022
By:
- Si, Xiaohui;
- Xiao, Lu;
- Brown, Christine E.;
- Wang, Dongrui
Publication type:
Literature Review
1045. Targeted Elimination of the Brain Tumor Initiating Cell Population with Adoptively Transferred T Cells.
Published in:
Molecular Therapy, 2006, v. 13, p. S401, doi. 10.1016/j.ymthe.2006.08.1141
By:
- Brown, Christine E.;
- Starr, Renate;
- Korta, Dorota;
- Aguilar, Brenda;
- Jensen, Michael C.
Publication type:
Article
272. Conversion of a Tumor-Binding Peptide Identified by Phage Display to a Functional Chimeric T-Cell Antigen Receptor.
Published in:
Molecular Therapy, 2006, v. 13, p. S104, doi. 10.1016/j.ymthe.2006.08.326
By:
- Pameijer, Colette R. J.;
- Hamlett, Araceli;
- Meechovet, Bessie;
- Buckmaster, Jamie;
- Aguilar, Brenda;
- Wright, Christine;
- Chung Chang, Wen-;
- Brown, Christine E.;
- Jensen, Michael C.
Publication type:
Article
619. Tumor-Derived Chemokine MCP-1/CCL2 Is Sufficient for Mediating Tumor Tropism of Adoptively Transferred T-Cells.
Published in:
Molecular Therapy, 2006, v. 13, p. S239, doi. 10.1016/j.ymthe.2006.08.694
By:
- Brown, Christine E.;
- Vishwanath, Reena;
- Aguilar, Brenda;
- WenChung Chang;
- Jensen, Michael C.
Publication type:
Article
IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma.
Published in:
Neuro-Oncology, 2024, v. 26, n. 10, p. 1850, doi. 10.1093/neuonc/noae126
By:
- Hou, Andrew J;
- Shih, Ryan M;
- Uy, Benjamin R;
- Shafer, Amanda;
- Chang, ZeNan L;
- Comin-Anduix, Begonya;
- Guemes, Miriam;
- Galic, Zoran;
- Phyu, Su;
- Okada, Hideho;
- Grausam, Katie B;
- Breunig, Joshua J;
- Brown, Christine E;
- Nathanson, David A;
- Prins, Robert M;
- Chen, Yvonne Y
Publication type:
Article
Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16160-5
By:
- Zah, Eugenia;
- Nam, Eunwoo;
- Bhuvan, Vinya;
- Tran, Uyen;
- Ji, Brenda Y.;
- Gosliner, Stanley B.;
- Wang, Xiuli;
- Brown, Christine E.;
- Chen, Yvonne Y.
Publication type:
Article
Human Neural Stem Cell Biodistribution and Predicted Tumor Coverage by a Diffusible Therapeutic in a Mouse Glioma Model.
Published in:
Stem Cells Translational Medicine, 2017, v. 6, n. 6, p. 1522, doi. 10.1002/sctm.16-0397
By:
- Barish, Michael E.;
- Herrmann, Kelsey;
- Tang, Yang;
- Argalian Herculian, Siranush;
- Metz, Marianne;
- Aramburo, Soraya;
- Tirughana, Revathiswari;
- Gutova, Margarita;
- Annala, Alexander;
- Moats, Rex A.;
- Goldstein, Leanne;
- Rockne, Russell C.;
- Gutierrez, Jennifer;
- Brown, Christine E.;
- Ghoda, Lucy;
- Aboody, Karen S.
Publication type:
Article
Neural Stem Cell-Mediated Delivery of Irinotecan-Activating Carboxylesterases to Glioma: Implications for Clinical Use.
Published in:
Stem Cells Translational Medicine, 2013, v. 2, n. 12, p. 983, doi. 10.5966/sctm.2012-0177
By:
- METZ, MARIANNE Z.;
- GUTOVA, MARGARITA;
- LACEY, SIMON F.;
- ABRAMYANTS, YELENA;
- TIEN VO;
- GILCHRIST, MEGAN;
- TIRUGHANA, REVATHISWARI;
- GHODA, LUCY Y.;
- BARISH, MICHAEL E.;
- BROWN, CHRISTINE E.;
- NAJBAUER, JOSEPH;
- POTTER, PHILIP M.;
- PORTNOW, JANA;
- SYNOLD, TIMOTHY W.;
- ABOODY, KAREN S.
Publication type:
Article
PGE2-EP2/EP4 signaling elicits mesoCAR T cell immunosuppression in pancreatic cancer.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1209572
By:
- Akbari, Behnia;
- Soltantoyeh, Tahereh;
- Shahosseini, Zahra;
- Jadidi-Niaragh, Farhad;
- Hadjati, Jamshid;
- Brown, Christine E.;
- Mirzaei, Hamid Reza
Publication type:
Article
Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1115536
By:
- Brummer, Alexander B.;
- Xella, Agata;
- Woodall, Ryan;
- Adhikarla, Vikram;
- Cho, Heyrim;
- Gutova, Margarita;
- Brown, Christine E.;
- Rockne, Russell C.
Publication type:
Article
Harnessing and Enhancing Macrophage Phagocytosis for Cancer Therapy.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.635173
By:
- Chen, Siqi;
- Lai, Seigmund W. T.;
- Brown, Christine E.;
- Feng, Mingye
Publication type:
Article
Cytokine Induction of VCAM-1 but Not IL13Rα2 on Glioma Cells: A Tale of Two Antibodies.
Published in:
PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0095123
By:
- Mahadev, Vaidehi;
- Starr, Renate;
- Wright, Sarah L.;
- Martinez, Catalina;
- Jensen, Michael C.;
- Barish, Michael E.;
- Forman, Stephen J.;
- Brown, Christine E.
Publication type:
Article
A Novel Berbamine Derivative Inhibits Cell Viability and Induces Apoptosis in Cancer Stem-Like Cells of Human Glioblastoma, via Up-Regulation of miRNA-4284 and JNK/AP-1 Signaling.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094443
By:
- Yang, Fan;
- Nam, Sangkil;
- Brown, Christine E.;
- Zhao, Robin;
- Starr, Renate;
- Horne, David A.;
- Malkas, Linda H.;
- Jove, Richard;
- Hickey, Robert J.
Publication type:
Article
Glioma IL13Rα2 Is Associated with Mesenchymal Signature Gene Expression and Poor Patient Prognosis.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077769
By:
- Brown, Christine E.;
- Warden, Charles D.;
- Starr, Renate;
- Deng, Xutao;
- Badie, Behnam;
- Yuan, Yate-Ching;
- Forman, Stephen J.;
- Barish, Michael E.
Publication type:
Article
Engineering Human T Cells for Resistance to Methotrexate and Mycophenolate Mofetil as an <i>In Vivo</i> Cell Selection Strategy.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065519
By:
- Jonnalagadda, Mahesh;
- Brown, Christine E.;
- Chang, Wen-Chung;
- Ostberg, Julie R.;
- Forman, Stephen J.;
- Jensen, Michael C.
Publication type:
Article
Contact and Encirclement of Glioma Cells In Vitro Is an Intrinsic Behavior of a Clonal Human Neural Stem Cell Line.
Published in:
PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051859
By:
- Khosh, Nousha;
- Brown, Christine E.;
- Aboody, Karen S.;
- Barish, Michael E.
Publication type:
Article
Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0036248
By:
- Ming-Fei Lang;
- Su Yang;
- Chunnian Zhao;
- Guoqiang Sun;
- Kiyohito Murai;
- Xiwei Wu;
- Jinhui Wang;
- Hanlin Gao;
- Christine E. Brown;
- Xiaoxuan Liu;
- Jiehua Zhou;
- Ling Peng;
- JohnJ Rossi;
- Yanhong Shi
Publication type:
Article
Cytotoxic T Lymphocyte Trafficking and Survival in an Augmented Fibrin Matrix Carrier.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034652
By:
- Zhaoxia Zou;
- Denny, Erin;
- Brown, Christine E.;
- Jensen, Michael C.;
- Gang Li;
- Fujii, Tatsuhiro;
- Neman, Josh;
- Jandial, Rahul;
- Chen, Mike
Publication type:
Article
The future of cancer immunotherapy for brain tumors: a collaborative workshop.
Published in:
2022
By:
- Brown, Christine E.;
- Bucktrout, Samantha;
- Butterfield, Lisa H.;
- Futer, Olga;
- Galanis, Evanthia;
- Hormigo, Adilia;
- Lim, Michael;
- Okada, Hideho;
- Prins, Robert;
- Marr, Sara Siebel;
- Tanner, Kirk
Publication type:
journal article
Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy.
Published in:
PLoS Computational Biology, 2022, v. 18, n. 1, p. 1, doi. 10.1371/journal.pcbi.1009504
By:
- Brummer, Alexander B.;
- Yang, Xin;
- Ma, Eric;
- Gutova, Margarita;
- Brown, Christine E.;
- Rockne, Russell C.
Publication type:
Article