Works by Brown, Alistair J P

Results: 84

Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 10, p. 693, doi. 10.1038/nrmicro2875

By:

Leach, Michelle D.;
Klipp, Edda;
Cowen, Leah E.;
Brown, Alistair J. P.

Publication type:

Article

Candida albicans morphogenesis and host defence: discriminating invasion from colonization.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 2, p. 112, doi. 10.1038/nrmicro2711

By:

Gow, Neil A. R.;
van de Veerdonk, Frank L.;
Brown, Alistair J. P.;
Netea, Mihai G.

Publication type:

Article

Impact of the transcriptional regulator, Ace2, on the Candida glabrata secretome.

Published in:

Proteomics, 2010, v. 10, n. 2, p. 212, doi. 10.1002/pmic.200800706

By:

Stead, David A.;
Walker, Janet;
Holcombe, Lucy;
Gibbs, Samuel R. S.;
Yin, Zhikang;
Selway, Laura;
Butler, Geraldine;
Brown, Alistair J. P.;
Haynes, Ken

Publication type:

Article

A proteomic analysis of the salt, cadmium and peroxide stress responses in Candida albicans and the role of the Hog1 stress-activated MAPK in regulating the stress-induced proteome.

Published in:

Proteomics, 2009, v. 9, n. 20, p. 4686, doi. 10.1002/pmic.200800958

By:

Yin, Zhikang;
Stead, David;
Walker, Jan;
Selway, Laura;
Smith, Deborah A.;
Brown, Alistair J. P.;
Quinn, Janet

Publication type:

Article

Proteomic analysis of the pH response in the fungal pathogen Candida glabrata.

Published in:

Proteomics, 2008, v. 8, n. 3, p. 534, doi. 10.1002/pmic.200700845

By:

Schmidt, Pia;
Walker, Janet;
Selway, Laura;
Stead, David;
Yin, Zhikang;
Enjalbert, Brice;
Weig, Michael;
Brown, Alistair J. P.

Publication type:

Article

Proteomic changes associated with inactivation of the Candida glabrata ACE2 virulence-moderating gene.

Published in:

Proteomics, 2005, v. 5, n. 7, p. 1838, doi. 10.1002/pmic.200401064

By:

David Stead;
Helen Findon;
Zhikang Yin;
Janet Walker;
Laura Selway;
Philip Cash;
Bernard A. Dujon;
Christophe Hennequin;
Alistair J. P. Brown;
Ken Haynes

Publication type:

Article

Proteomic response to amino acid starvation inCandida albicans and Saccharomyces cerevisiae.

Published in:

Proteomics, 2004, v. 4, n. 8, p. 2425, doi. 10.1002/pmic.200300760

By:

Zhikang Yin;
David Stead;
Laura Selway;
Janet Walker;
Isabel Riba-Garcia;
Tracey Mclnerney;
Simon Gaskell;
Stephen G. Oliver;
Philip Cash;
Alistair J. P. Brown

Publication type:

Article

The PKC, HOG and Ca<sup>2+</sup> signalling pathways co-ordinately regulate chitin synthesis in Candida albicans.

Published in:

Molecular Microbiology, 2007, v. 63, n. 5, p. 1399, doi. 10.1111/j.1365-2958.2007.05588.x

By:

Munro, Carol A.;
Selvaggini, Serena;
De Bruijn, Irene;
Walker, Louise;
Lenardon, Megan D.;
Gerssen, Bertus;
Milne, Sarah;
Brown, Alistair J. P.;
Gow, Neil A. R.

Publication type:

Article

Glucose triggers different global responses in yeast, depending on the strength of the signal, and transiently stabilizes ribosomal protein mRNAs.

Published in:

Molecular Microbiology, 2003, v. 48, n. 3, p. 713, doi. 10.1046/j.1365-2958.2003.03478.x

By:

Yin, Zhikang;
Wilson, Séan;
Hauser, Nicole C.;
Tournu, Helene;
Hoheisel, Jörg D.;
Brown, Alistair J. P.

Publication type:

Article

Chs1 of Candida albicans is an essential chitin synthase required for synthesis of the septum and for cell integrity.

Published in:

Molecular Microbiology, 2001, v. 39, n. 5, p. 1414, doi. 10.1046/j.1365-2958.2001.02347.x

By:

Munro, Carol A.;
Winter, Ken;
Buchan, Arlene;
Henry, Keith;
Becker, Jeffrey M.;
Brown, Alistair J. P.;
Bulawa, Christine E.;
Gow, Neil A. R.

Publication type:

Article

Differential post-transcriptional regulation of yeast mRNAs in response to high and low glucose concentrations.

Published in:

Molecular Microbiology, 2000, v. 35, n. 3, p. 553, doi. 10.1046/j.1365-2958.2000.01723.x

By:

Yin, Zhikang;
Hatton, Lee;
Brown, Alistair J. P

Publication type:

Article

Transcriptomic and proteomic profiling revealed reprogramming of carbon metabolism in acetate-grown human pathogen Candida glabrata.

Published in:

Journal of Biomedical Science, 2021, v. 28, n. 1, p. 1, doi. 10.1186/s12929-020-00700-8

By:

Chew, Shu Yih;
Brown, Alistair J. P.;
Lau, Benjamin Yii Chung;
Cheah, Yoke Kqueen;
Ho, Kok Lian;
Sandai, Doblin;
Yahaya, Hassan;
Than, Leslie Thian Lung

Publication type:

Article

GFP as a quantitative reporter of gene regulation in Candida albicans.

Published in:

Yeast, 2004, v. 21, n. 4, p. 333, doi. 10.1002/yea.1099

By:

Barelle, Caroline J.;
Manson, Claire L.;
MacCallum, Donna M.;
Odds, Frank C.;
Gow, Neil A. R.;
Brown, Alistair J. P.

Publication type:

Article

Protein A-tagging for purification of native macromolecular complexes from Candida albicans.

Published in:

Yeast, 2003, v. 20, n. 15, p. 1235, doi. 10.1002/yea.1036

By:

Chris Blackwell;
Claire L. Russell;
Silvia Argimon;
Alistair J. P. Brown;
Jeremy D. Brown

Publication type:

Article

CIp10, an efficient and convenient integrating vector for Candida albicans.

Published in:

Yeast, 2000, v. 16, n. 4, p. 325, doi. 10.1002/1097-0061(20000315)16:4<325::AID-YEA538>3.0.CO;2-#

By:

Murad, Abdul Munir Abdul;
Lee, Philip R.;
Broadbent, Ian D.;
Barelle, Caroline J.;
Brown, Alistair J. P.

Publication type:

Article

Transcript analysis of 250 novel yeast genes from chromosome XIV.

Published in:

Yeast, 1999, v. 15, n. 4, p. 329, doi. 10.1002/(SICI)1097-0061(19990315)15:4<329::AID-YEA360>3.0.CO;2-C

By:

Planta, Rudi J.;
Brown, Alistair J. P.;
Cadahia, Jose L.;
Esperanza Cerdan, M.;
De Jonge, Martine;
Gent, Manda E.;
Hayes, Andrew;
Kolen, Carin P. A. M.;
Lombardia, Luis J.;
Sefton, Mark;
Oliver, Stephen G.;
Thevelein, Johan;
Tournu, Helene;
van Delft, Yvon J.;
Verbart, Dennis J.;
Winderickx, Joris

Publication type:

Article

Over-expression of candida albicans mitochondrial ribosomal protein S9 (MrpS9p) disturbs mitochondrial function in Saccharomyces cerevisiae.

Published in:

Yeast, 1999, v. 15, n. 2, p. 139, doi. 10.1002/(SICI)1097-0061(19990130)15:2<139::AID-YEA347>3.0.CO;2-5

By:

Wiltshire, Carolyn;
Black, Sheila;
Brown, Alistair J. P.

Publication type:

Article

Structure and regulation of the Candida albicans ADH1 gene encoding an immunogenic alcohol dehydrogenase.

Published in:

Yeast, 1996, v. 12, n. 2, p. 115, doi. 10.1002/(SICI)1097-0061(199602)12:2<115::AID-YEA889>3.0.CO;2-E

By:

Bertram, Gwyneth;
Swoboda, Rolf K.;
Gooday, Graham W.;
Gow, Neil A. R.;
Brown, Alistair J. P.

Publication type:

Article

A physical comparison of chromosome III in six strains of Saccharomyces cerevisiae.

Published in:

Yeast, 1994, v. 10, n. 1, p. 39, doi. 10.1002/yea.320100105

By:

Wicksteed, Barton L.;
Collins, Irene;
Dershowitz, Ann;
Stateva, Lubomira I.;
Green, Rebecca P.;
Oliver, Stephen G.;
Brown, Alistair J. P.;
Newlon, Carol S.

Publication type:

Article

The complete sequence of a 7·5 kb region of chromosome III from Saccharomyces cerevisiae that lies between CRY1 and MAT.

Published in:

Yeast, 1991, v. 7, n. 7, p. 761, doi. 10.1002/yea.320070711

By:

Wicksteed, Barton L.;
Roberts, A. Brett;
Sagliocco, Francis A.;
Brown, Alistair J. P.

Publication type:

Article

Messenger RNA stability in yeast.

Published in:

Yeast, 1989, v. 5, n. 4, p. 239, doi. 10.1002/yea.320050405

By:

Brown, Alistair J. P.

Publication type:

Article

5′-Secondary structure formation, in constrast to a short string of non-preferred codons, inhibits the translation of the pyruvate kinase mRNA in yeast.

Published in:

Yeast, 1989, v. 5, n. 3, p. 187, doi. 10.1002/yea.320050308

By:

Bettany, Andrew J. E.;
Moore, Paul A.;
Cafferkey, Robert;
Bell, Les D.;
Goodey, Andrew R.;
Carter, Bruce L. A.;
Brown, Alistair J. P.

Publication type:

Article

Candida albicans N-Linked Mannans Potentiate the Induction of Trained Immunity via Dectin-2.

Published in:

Journal of Infectious Diseases, 2024, v. 230, n. 3, p. 768, doi. 10.1093/infdis/jiae112

By:

Rosati, Diletta;
Pradhan, Arnab;
Heck, Julia I P van;
Helder, Leonie;
Jaeger, Martin;
Gow, Neil A R;
Joosten, Leo A B;
Williams, David L;
Brown, Alistair J P;
Bruno, Mariolina;
Netea, Mihai G

Publication type:

Article

Metabolic modelling as a powerful tool to identify critical components of Pneumocystis growth medium.

Published in:

PLoS Computational Biology, 2024, v. 20, n. 10, p. 1, doi. 10.1371/journal.pcbi.1012545

By:

Nev, Olga A.;
Zamaraeva, Elena;
De Oliveira, Romain;
Ryzhkov, Ilia;
Duvenage, Lucian;
Abou-Jaoudé, Wassim;
Ouattara, Djomangan Adama;
Hoving, Jennifer Claire;
Gudelj, Ivana;
Brown, Alistair J. P.

Publication type:

Article

Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors.

Published in:

2006

By:

Netea, Mihai G.;
Gow, Neil A. R.;
Munro, Carol A.;
Bates, Steven;
Collins, Claire;
Ferwerda, Gerben;
Hobson, Richard P.;
Bertram, Gwyneth;
Hughes, H. Bleddyn;
Jansen, Trees;
Jacobs, Liesbeth;
Buurman, Ed T.;
Gijzen, Karlijn;
Williams, David L.;
Torensma, Ruurd;
McKinnon, Alistair;
MacCallum, Donna M.;
Odds, Frank C.;
Van der Meer, Jos W. M.;
Brown, Alistair J. P.

Publication type:

journal article

Azole antifungals induce up-regulation of SAP4, SAP5 and SAP6 secreted proteinase genes in filamentous Candida albicans cells in vitro and in vivo.

Published in:

2008

By:

Barelle, Caroline J;
Duncan, Vanessa M S;
Brown, Alistair J P;
Gow, Neil A R;
Odds, Frank C

Publication type:

journal article

Azole antifungals induce up-regulation of SAP4, SAP5 and SAP6 secreted proteinase genes in filamentous Candida albicans cells in vitro and in vivo.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2008, v. 61, n. 2, p. 315

By:

Caroline J. Barelle;
Vanessa M. S. Duncan;
Alistair J. P. Brown;
Neil A. R. Gow;
Frank C. Odds

Publication type:

Article

Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 55, n. 5, p. 645, doi. 10.1093/jac/dki088

By:

Vanessa M. S. Copping;
Caroline J. Barelle;
Bernhard Hube;
Neil A. R. Gow;
Alistair J. P. Brown;
Frank C. Odds

Publication type:

Article

Understanding the Role of Nitronate Monooxygenases in Virulence of the Human Fungal Pathogen Aspergillus fumigatus.

Published in:

Journal of Fungi, 2022, v. 8, n. 7, p. 736, doi. 10.3390/jof8070736

By:

Nguyen, Phuong Tuyen;
Wacker, Theresa;
Brown, Alistair J. P.;
da Silva Dantas, Alessandra;
Shekhova, Elena

Publication type:

Article

Antifungal Activity of Antimicrobial Peptides and Proteins against Aspergillus fumigatus.

Published in:

Journal of Fungi, 2020, v. 6, n. 2, p. 1, doi. 10.3390/jof6020065

By:

Ballard, Eloise;
Yucel, Raif;
Melchers, Willem J. G.;
Brown, Alistair J. P.;
Verweij, Paul E.;
Warris, Adilia

Publication type:

Article

Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections.

Published in:

PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0158683

By:

Mackie, Joanna;
Szabo, Edina K.;
Urgast, Dagmar S.;
Ballou, Elizabeth R.;
Childers, Delma S.;
MacCallum, Donna M.;
Feldmann, Joerg;
Brown, Alistair J. P.

Publication type:

Article

Plasmids for in vivo construction of integrative Candida albicans vectors in Saccharomyces cerevisiae.

Published in:

Yeast, 2010, v. 27, n. 11, p. 933, doi. 10.1002/yea.1800

By:

Vieira, Neide;
Pereira, Filipa;
Casal, Margarida;
Brown, Alistair J. P.;
Paiva, Sandra;
Johansson, Björn

Publication type:

Article

A quantitative model for mRNA translation in Saccharomyces cerevisiae.

Published in:

Yeast, 2010, v. 27, n. 10, p. 785, doi. 10.1002/yea.1770

By:

You, Tao;
Coghill, George M;
Brown, Alistair J. P.

Publication type:

Article

Elevated catalase expression in a fungal pathogen is a double-edged sword of iron.

Published in:

PLoS Pathogens, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.ppat.1006405

By:

Pradhan, Arnab;
Herrero-de-Dios, Carmen;
Belmonte, Rodrigo;
Budge, Susan;
Lopez Garcia, Angela;
Kolmogorova, Aljona;
Lee, Keunsook K.;
Martin, Brennan D.;
Ribeiro, Antonio;
Bebes, Attila;
Yuecel, Raif;
Gow, Neil A. R.;
Munro, Carol A.;
MacCallum, Donna M.;
Quinn, Janet;
Brown, Alistair J. P.

Publication type:

Article

The environmental stress sensitivities of pathogenic Candida species, including Candida auris, and implications for their spread in the hospital setting.

Published in:

Medical Mycology, 2020, v. 58, n. 6, p. 744, doi. 10.1093/mmy/myz127

By:

Heaney, Helen;
Laing, Juliette;
Paterson, Linda;
Walker, Alan W;
Gow, Neil A R;
Johnson, Elizabeth M;
MacCallum, Donna M;
Brown, Alistair J P

Publication type:

Article

Glycosylation status of the C. albicans cell wall affects the efficiency of neutrophil phagocytosis and killing but not cytokine signaling.

Published in:

Medical Mycology, 2011, v. 49, n. 5, p. 513, doi. 10.3109/13693786.2010.551425

By:

Sheth, Chirag C.;
Hall, Rebecca;
Lewis, Leanne;
Brown, Alistair J. P.;
Odds, Frank C.;
Erwig, Lars P.;
Gow, Neil A. R.

Publication type:

Article

Carbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen C andida albicans.

Published in:

Proteomics, 2012, v. 12, n. 21, p. 3164, doi. 10.1002/pmic.201200228

By:

Ene, Iuliana V.;
Heilmann, Clemens J.;
Sorgo, Alice G.;
Walker, Louise A.;
de Koster, Chris G.;
Munro, Carol A.;
Klis, Frans M.;
Brown, Alistair J. P.

Publication type:

Article

Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source.

Published in:

NPJ Biofilms & Microbiomes, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41522-020-0114-5

By:

Alves, Rosana;
Kastora, Stavroula L.;
Gomes-Gonçalves, Alexandra;
Azevedo, Nuno;
Rodrigues, Célia F.;
Silva, Sónia;
Demuyser, Liesbeth;
Van Dijck, Patrick;
Casal, Margarida;
Brown, Alistair J. P.;
Henriques, Mariana;
Paiva, Sandra

Publication type:

Article

Information quality in proteomics.

Published in:

Briefings in Bioinformatics, 2008, v. 9, n. 2, p. 174, doi. 10.1093/bib/bbn004

By:

Stead, David A.;
Paton, Norman W.;
Missir, Paolo;
Embury, Suzanne M.;
Hedeler, Cornelia;
Jin, Binling;
Brown, Alistair J. P.;
Preece, Alun

Publication type:

Article

Phylogenetic diversity of stress signalling pathways in fungi.

Published in:

BMC Evolutionary Biology, 2009, v. 9, p. 1, doi. 10.1186/1471-2148-9-44

By:

Nikolaou, Elissavet;
Agrafioti, Ino;
Stumpf, Michael;
Quinn, Janet;
Stansfield, Ian;
Brown, Alistair J. P.

Publication type:

Article

Glyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrata.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39117-1

By:

Chew, Shu Yih;
Ho, Kok Lian;
Cheah, Yoke Kqueen;
Ng, Tzu Shan;
Sandai, Doblin;
Brown, Alistair J. P.;
Than, Leslie Thian Lung

Publication type:

Article

Niche-specific regulation of central metabolic pathways in a fungal pathogen.

Published in:

Cellular Microbiology, 2006, v. 8, n. 6, p. 961, doi. 10.1111/j.1462-5822.2005.00676.x

By:

Barelle, Caroline J.;
Priest, Claire L.;
MacCallum, Donna M.;
Gow, Neil A. R.;
Odds, Frank C.;
Brown, Alistair J. P.

Publication type:

Article

A quantitative model for the GCN4 translational control in Saccharomyces cerevisiae.

Published in:

2007

By:

Tao You;
Brown, Alistair J. P.;
Coghill, George M.

Publication type:

Abstract

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation.

Published in:

PLoS Pathogens, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.ppat.1004050

By:

Wagener, Jeanette;
Malireddi, R. K. Subbarao;
Lenardon, Megan D.;
Köberle, Martin;
Vautier, Simon;
MacCallum, Donna M.;
Biedermann, Tilo;
Schaller, Martin;
Netea, Mihai G.;
Kanneganti, Thirumala-Devi;
Brown, Gordon D.;
Brown, Alistair J. P.;
Gow, Neil A. R.

Publication type:

Article

Conflicting Interests in the Pathogen–Host Tug of War: Fungal Micronutrient Scavenging Versus Mammalian Nutritional Immunity.

Published in:

PLoS Pathogens, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.ppat.1003910

By:

Potrykus, Joanna;
Ballou, Elizabeth R.;
Childers, Delma S.;
Brown, Alistair J. P.

Publication type:

Article

Fungal Iron Availability during Deep Seated Candidiasis Is Defined by a Complex Interplay Involving Systemic and Local Events.

Published in:

PLoS Pathogens, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.ppat.1003676

By:

Potrykus, Joanna;
Stead, David;
MacCallum, Donna M.;
Urgast, Dagmar S.;
Raab, Andrea;
van Rooijen, Nico;
Feldmann, Jörg;
Brown, Alistair J. P.

Publication type:

Article

Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1.

Published in:

PLoS Pathogens, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.ppat.1003315

By:

Marakalala, Mohlopheni J.;
Vautier, Simon;
Potrykus, Joanna;
Walker, Louise A.;
Shepardson, Kelly M.;
Hopke, Alex;
Mora-Montes, Hector M.;
Kerrigan, Ann;
Netea, Mihai G.;
Murray, Graeme I.;
MacCallum, Donna M.;
Wheeler, Robert;
Munro, Carol A.;
Gow, Neil A. R.;
Cramer, Robert A.;
Brown, Alistair J. P.;
Brown, Gordon D.

Publication type:

Article

The Mnn2 Mannosyltransferase Family Modulates Mannoprotein Fibril Length, Immune Recognition and Virulence of Candida albicans.

Published in:

PLoS Pathogens, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.ppat.1003276

By:

Hall, Rebecca A.;
Bates, Steven;
Lenardon, Megan D.;
MacCallum, Donna M.;
Wagener, Jeanette;
Lowman, Douglas W.;
Kruppa, Michael D.;
Williams, David L.;
Odds, Frank C.;
Brown, Alistair J. P.;
Gow, Neil A. R.

Publication type:

Article

Hsp90 Orchestrates Transcriptional Regulation by Hsf1 and Cell Wall Remodelling by MAPK Signalling during Thermal Adaptation in a Pathogenic Yeast.

Published in:

PLoS Pathogens, 2012, v. 8, n. 12, p. 1, doi. 10.1371/journal.ppat.1003069

By:

Leach, Michelle D.;
Budge, Susan;
Walker, Louise;
Munro, Carol;
Cowen, Leah E.;
Brown, Alistair J. P.

Publication type:

Article

Oma1 Links Mitochondrial Protein Quality Control and TOR Signaling To Modulate Physiological Plasticity and Cellular Stress Responses.

Published in:

Molecular & Cellular Biology, 2016, v. 36, n. 17, p. 2300, doi. 10.1128/MCB.00156-16

By:

Bohovych, Iryna;
Kastora, Stavroula;
Christianson, Sara;
Topil, Danelle;
Heejeong Kim;
Fangman, Teresa;
Zhou, You J.;
Barrientos, Antoni;
Jaekwon Lee;
Brown, Alistair J. P.;
Khalimonchuk, Oleh

Publication type:

Article