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Hitting the bull's eye: Novel directed cancer therapy through helicase-targeted synthetic lethality.
- Published in:
- Journal of Cellular Biochemistry, 2009, v. 106, n. 5, p. 758, doi. 10.1002/jcb.22048
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- Publication type:
- Article
Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product.
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- Oncogene, 2002, v. 21, n. 22, p. 3571, doi. 10.1038/sj.onc.1205443
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- Article
Role of the ATPase domain of the Cockayne syndrome group B protein in UV induced apoptosis.
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- Oncogene, 2000, v. 19, n. 4, p. 477, doi. 10.1038/sj.onc.1203372
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- Article
Replication stress as a driver of cellular senescence and aging.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06263-w
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- Publication type:
- Article
In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication.
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- Human Molecular Genetics, 2004, v. 13, n. 19, p. 2247, doi. 10.1093/hmg/ddh234
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- Article
CDK1 phosphorylates WRN at collapsed replication forks.
- Published in:
- Nature Communications, 2016, v. 7, n. 9, p. 12880, doi. 10.1038/ncomms12880
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- Article
RecQ and Fe-S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions.
- Published in:
- Biochemical Society Transactions, 2018, v. 46, n. 1, p. 77, doi. 10.1042/BST20170044
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- Article
Special Issue on DNA Replication Stress: Summary of Topics Covered.
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- 2019
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- Publication type:
- Editorial
Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism.
- Published in:
- International Journal of Molecular Sciences, 2017, v. 18, n. 6, p. 1233, doi. 10.3390/ijms18061233
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- Article
Molecular biology: The Bloom's complex mousetrap.
- Published in:
- Nature, 2008, v. 456, n. 7221, p. 453, doi. 10.1038/456453a
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- Article
Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia.
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- Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00372
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- Publication type:
- Article
The transcriptional response after oxidative stress is defective in Cockayne syndrome group B cells.
- Published in:
- Oncogene, 2003, v. 22, n. 8, p. 1135, doi. 10.1038/sj.onc.1206187
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- Publication type:
- Article
Special Issue: DNA Helicases: Mechanisms, Biological Pathways, and Disease Relevance.
- Published in:
- 2021
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- Publication type:
- Editorial
History of DNA Helicases.
- Published in:
- Genes, 2020, v. 11, n. 3, p. 255, doi. 10.3390/genes11030255
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- Publication type:
- Article
FANCJ/BACH1 Acetylation at Lysine 1249 Regulates the DNA Damage Response.
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- PLoS Genetics, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.pgen.1002786
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- Publication type:
- Article
Holding All the Cards—How Fanconi Anemia Proteins Deal with Replication Stress and Preserve Genomic Stability.
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- Genes, 2019, v. 10, n. 2, p. 170, doi. 10.3390/genes10020170
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- Publication type:
- Article
Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles.
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- Genes, 2016, v. 7, n. 7, p. 31, doi. 10.3390/genes7070031
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- Publication type:
- Article
DNA repair and mutagenesis in Werner syndrome.
- Published in:
- Environmental & Molecular Mutagenesis, 2001, v. 38, n. 2/3, p. 227, doi. 10.1002/em.1076
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- Publication type:
- Article
Human RECQ1 Interacts with Ku70/80 and Modulates DNA End-Joining of Double-Strand Breaks
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062481
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- Publication type:
- Article
DNA helicases involved in DNA repair and their roles in cancer.
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- Nature Reviews Cancer, 2013, v. 13, n. 8, p. 542, doi. 10.1038/nrc3560
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- Publication type:
- Article
Protein Degradation Pathways Regulate the Functions of Helicases in the DNA Damage Response and Maintenance of Genomic Stability.
- Published in:
- Biomolecules (2218-273X), 2015, v. 5, n. 2, p. 590, doi. 10.3390/biom5020590
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- Publication type:
- Article
WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26811-w
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- Publication type:
- Article
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome.
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- EMBO Journal, 2011, v. 30, n. 4, p. 692, doi. 10.1038/emboj.2010.362
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- Article
The FANCJ/MutLα interaction is required for correction of the cross-link response in FA-J cells.
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- EMBO Journal, 2007, v. 26, n. 13, p. 3238, doi. 10.1038/sj.emboj.7601754
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- Publication type:
- Article
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.
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- EMBO Journal, 2001, v. 20, n. 20, p. 5791, doi. 10.1093/emboj/20.20.5791
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- Publication type:
- Article
Pathways defective in the human premature aging disease Werner syndrome.
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- Biogerontology, 2002, v. 3, n. 1/2, p. 89, doi. 10.1023/A:1015223917491
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- Publication type:
- Article
An emerging picture of FANCJ's role in G4 resolution to facilitate DNA replication.
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- NAR Cancer, 2021, v. 3, n. 3, p. 1, doi. 10.1093/narcan/zcab034
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- Publication type:
- Article
FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links.
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- Nucleic Acids Research, 2020, v. 48, n. 16, p. 9161, doi. 10.1093/nar/gkaa660
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- Publication type:
- Article
Expression of Concern: Detection of G-quadruplex DNA in mammalian cells.
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- Nucleic Acids Research, 2017, v. 45, n. 10, p. 6252, doi. 10.1093/nar/gkx300
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- Publication type:
- Article
G-quadruplexes and helicases.
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- Nucleic Acids Research, 2016, v. 44, n. 5, p. 1989, doi. 10.1093/nar/gkw079
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- Publication type:
- Article
Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway.
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- Nucleic Acids Research, 2016, v. 44, n. 2, p. 705, doi. 10.1093/nar/gkv1112
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- Publication type:
- Article
Detection of G-quadruplex DNA in mammalian cells.
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- Nucleic Acids Research, 2014, v. 42, n. 2, p. 860, doi. 10.1093/nar/gkt957
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- Publication type:
- Article
DNA helicase and helicase–nuclease enzymes with a conserved iron–sulfur cluster.
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- Nucleic Acids Research, 2012, v. 40, n. 10, p. 4247
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- Publication type:
- Article
Identification of phage antibodies toward the Werner protein by selection on Western blots.
- Published in:
- Electrophoresis, 2000, v. 21, n. 3, p. 509, doi. 10.1002/(SICI)1522-2683(20000201)21:3<509::AID-ELPS509>3.0.CO;2-5
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- Publication type:
- Article
Human premature aging, DNA repair and RecQ helicases.
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- Nucleic Acids Research, 2007, v. 35, n. 22, p. 7527, doi. 10.1093/nar/gkm1008
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- Publication type:
- Article
Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand.
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- Nucleic Acids Research, 2006, v. 34, n. 22, p. 6673, doi. 10.1093/nar/gkl964
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- Publication type:
- Article
Cockayne syndrome group B protein has novel strand annealing and exchange activities.
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- Nucleic Acids Research, 2006, v. 34, n. 1, p. 295, doi. 10.1093/nar/gkj410
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- Publication type:
- Article
The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA.
- Published in:
- Nucleic Acids Research, 2005, v. 33, n. 21, p. 6769, doi. 10.1093/nar/gki1002
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- Article
Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A.
- Published in:
- Nucleic Acids Research, 2004, v. 32, n. 7, p. 2158, doi. 10.1093/nar/gkh540
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- Article
Functional consequences of mutations in the conserved SF2 motifs and post‐translational phosphorylation of the CSB protein.
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- Nucleic Acids Research, 2003, v. 31, n. 3, p. 963, doi. 10.1093/nar/gkg164
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- Publication type:
- Article
Differential requirement for the ATPase domain of the Cockayne syndrome group B gene in the processing of UV-induced DNA damage and 8-oxoguanine lesions in human cells.
- Published in:
- Nucleic Acids Research, 2002, v. 30, n. 3, p. 782, doi. 10.1093/nar/30.3.782
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- Publication type:
- Article
The Bloom’s and Werner’s syndrome proteins are DNA structure-specific helicases.
- Published in:
- Nucleic Acids Research, 2001, v. 29, n. 13, p. 2843, doi. 10.1093/nar/29.13.2843
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- Publication type:
- Article
Molecular characterization of an acidic region deletion mutant of Cockayne syndrome group B protein.
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- Nucleic Acids Research, 2000, v. 28, n. 16, p. 3151, doi. 10.1093/nar/28.16.3151
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- Publication type:
- Article
Potent inhibition of Werner and Bloom helicases by DNA minor groove binding drugs.
- Published in:
- Nucleic Acids Research, 2000, v. 28, n. 12, p. 2420, doi. 10.1093/nar/28.12.2420
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- Publication type:
- Article
Identification and Biochemical Characterization of a Novel Mutation in DDX11 Causing Warsaw Breakage Syndrome.
- Published in:
- Human Mutation, 2013, v. 34, n. 1, p. 103, doi. 10.1002/humu.22226
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- Article
Editorial: DNA repair and interventions in aging.
- Published in:
- Frontiers in Aging, 2023, p. 1, doi. 10.3389/fragi.2023.1306463
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- Publication type:
- Article
Frontiers in aging special issue: DNA repair and interventions in aging perspective on "loss of epigenetic information as a cause of mammalian aging".
- Published in:
- Frontiers in Aging, 2023, p. 1, doi. 10.3389/fragi.2023.1199596
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- Publication type:
- Article
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest.
- Published in:
- EMBO Reports, 2000, v. 1, n. 1, p. 80, doi. 10.1093/embo-reports/kvd004
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- Publication type:
- Article
Editorial: DNA repair and interventions in aging.
- Published in:
- Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fragi.2023.1306463
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- Publication type:
- Article
Warsaw breakage syndrome: Further clinical and genetic delineation.
- Published in:
- American Journal of Medical Genetics. Part A, 2018, v. 176, n. 11, p. 2404, doi. 10.1002/ajmg.a.40482
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- Publication type:
- Article