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A collagen extraction and deuterium oxide stable isotope tracer method for the quantification of bone collagen synthesis rates in vivo.
Published in:
Physiological Reports, 2021, v. 9, n. 10, p. 1, doi. 10.14814/phy2.14799
By:
- Civil, Rita;
- Brook, Matthew S.;
- Elliott‐Sale, Kirsty J.;
- Santos, Lívia;
- Varley, Ian;
- Lensu, Sanna;
- Kainulainen, Heikki;
- Koch, Lauren G.;
- Britton, Steven L.;
- Wilkinson, Daniel J.;
- Smith, Kenneth;
- Sale, Craig;
- Atherton, Philip J.
Publication type:
Article
Neither myonuclear accretion nor a myonuclear domain size ceiling is a feature of the attenuated hypertrophic potential of aged human skeletal muscle.
Published in:
GeroScience, 2023, v. 45, n. 1, p. 451, doi. 10.1007/s11357-022-00651-y
By:
- Brook, Matthew S.;
- Wilkinson, Daniel J.;
- Tarum, Janelle;
- Mitchell, Kyle W.;
- Lund, Jonathan L.;
- Phillips, Bethan E.;
- Szewczyk, Nathaniel J.;
- Kadi, Fawzi;
- Greenhaff, Paul L.;
- Smith, Ken;
- Atherton, Philip J.
Publication type:
Article
Metabolic and molecular responses of human patellar tendon to concentric- and eccentric-type exercise in youth and older age.
Published in:
GeroScience, 2023, v. 45, n. 1, p. 331, doi. 10.1007/s11357-022-00636-x
By:
- Crossland, Hannah;
- Brook, Matthew S.;
- Quinlan, Jonathan I.;
- Franchi, Martino V.;
- Phillips, Bethan E.;
- Wilkinson, Daniel J.;
- Maganaris, Constantinos N.;
- Greenhaff, Paul L.;
- Szewczyk, Nathaniel J.;
- Smith, Kenneth;
- Narici, Marco V.;
- Atherton, Philip J.
Publication type:
Article
The Combined Oral Stable Isotope Assessment of Muscle (COSIAM) reveals D-3 creatine derived muscle mass as a standout cross-sectional biomarker of muscle physiology vitality in older age.
Published in:
GeroScience, 2022, v. 44, n. 4, p. 2129, doi. 10.1007/s11357-022-00541-3
By:
- Cegielski, Jessica;
- Brook, Matthew S.;
- Phillips, Bethan E.;
- Boereboom, Catherine;
- Gates, Amanda;
- Gladman, John F. R.;
- Smith, Kenneth;
- Wilkinson, Daniel J.;
- Atherton, Philip J.
Publication type:
Article
Combined in vivo muscle mass, muscle protein synthesis and muscle protein breakdown measurement: a 'Combined Oral Stable Isotope Assessment of Muscle (COSIAM)' approach.
Published in:
GeroScience, 2021, v. 43, n. 6, p. 2653, doi. 10.1007/s11357-021-00386-2
By:
- Cegielski, Jessica;
- Wilkinson, Daniel J.;
- Brook, Matthew S.;
- Boereboom, Catherine;
- Phillips, Bethan E.;
- Gladman, John F. R.;
- Smith, Kenneth;
- Atherton, Philip J.
Publication type:
Article
Transcriptomic links to muscle mass loss and declines in cumulative muscle protein synthesis during short-term disuse in healthy younger humans.
Published in:
FASEB Journal, 2021, v. 35, n. 9, p. 1, doi. 10.1096/fj.202100276RR
By:
- Willis, Craig R. G.;
- Gallagher, Iain J.;
- Wilkinson, Daniel J.;
- Brook, Matthew S.;
- Bass, Joseph J.;
- Phillips, Bethan E.;
- Smith, Kenneth;
- Etheridge, Timothy;
- Stokes, Tanner;
- McGlory, Chris;
- Gorissen, Stefan H. M.;
- Szewczyk, Nathaniel J.;
- Phillips, Stuart M.;
- Atherton, Philip J.
Publication type:
Article
Higher strength gain after hypoxic vs normoxic resistance training despite no changes in muscle thickness and fractional protein synthetic rate.
Published in:
FASEB Journal, 2021, v. 35, n. 8, p. 1, doi. 10.1096/fj.202100654RR
By:
- van Doorslaer de ten Ryen, Sophie;
- Warnier, Geoffrey;
- Gnimassou, Olouyomi;
- Belhaj, Mehdi R.;
- Benoit, Nicolas;
- Naslain, Damien;
- Brook, Matthew S.;
- Smith, Kenneth;
- Wilkinson, Daniel J.;
- Nielens, Henri;
- Atherton, Philip J.;
- Francaux, Marc;
- Deldicque, Louise
Publication type:
Article
Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling.
Published in:
FASEB Journal, 2015, v. 29, n. 11, p. 4485, doi. 10.1096/fj.15-273755
By:
- Brook, Matthew S.;
- Wilkinson, Daniel J.;
- Mitchell, William K.;
- Lund, Jonathan N.;
- Szewczyk, Nathaniel J.;
- Greenhaff, Paul L.;
- Smith, Ken;
- Atherton, Philip J.
Publication type:
Article
The metabolic and temporal basis of muscle hypertrophy in response to resistance exercise.
Published in:
European Journal of Sport Science, 2016, v. 16, n. 6, p. 633, doi. 10.1080/17461391.2015.1073362
By:
- Brook, Matthew S.;
- Wilkinson, Daniel J.;
- Smith, Kenneth;
- Atherton, Philip J.
Publication type:
Article
Contemporary stable isotope tracer approaches: Insights into skeletal muscle metabolism in health and disease.
Published in:
Experimental Physiology, 2020, v. 105, n. 7, p. 1081, doi. 10.1113/EP087492
By:
- Brook, Matthew S.;
- Wilkinson, Daniel J.
Publication type:
Article
Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training.
Published in:
Experimental Physiology, 2018, v. 103, n. 11, p. 1513, doi. 10.1113/EP087144
By:
- Ahtiainen, Juha P.;
- Lensu, Sanna;
- Ruotsalainen, Ilona;
- Schumann, Moritz;
- Ihalainen, Johanna K.;
- Fachada, Vasco;
- Mendias, Christopher L.;
- Brook, Matthew S.;
- Smith, Kenneth;
- Atherton, Philip J.;
- Koch, Lauren G.;
- Britton, Steven L.;
- Kainulainen, Heikki
Publication type:
Article
The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo.
Published in:
Journal of Physiology, 2021, v. 599, n. 3, p. 963, doi. 10.1113/JP280652
By:
- Bass, Joseph J.;
- Kazi, Abid A.;
- Deane, Colleen S.;
- Nakhuda, Asif;
- Ashcroft, Stephen P.;
- Brook, Matthew S.;
- Wilkinson, Daniel J.;
- Phillips, Bethan E.;
- Philp, Andrew;
- Tarum, Janelle;
- Kadi, Fawzi;
- Andersen, Ditte;
- Garcia, Amadeo Muñoz;
- Smith, Ken;
- Gallagher, Iain J.;
- Szewczyk, Nathaniel J.;
- Cleasby, Mark E.;
- Atherton, Philip J
Publication type:
Article
Stable isotope tracers and exercise physiology: past, present and future.
Published in:
Journal of Physiology, 2017, v. 595, n. 9, p. 2873, doi. 10.1113/JP272277
By:
- Wilkinson, Daniel J.;
- Brook, Matthew S.;
- Smith, Kenneth;
- Atherton, Philip J.
Publication type:
Article
Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans.
Published in:
Journal of Physiology, 2016, v. 594, n. 24, p. 7399, doi. 10.1113/JP272857
By:
- Brook, Matthew S.;
- Wilkinson, Daniel J.;
- Mitchell, William K.;
- Lund, Jonathan N.;
- Phillips, Bethan E.;
- Szewczyk, Nathaniel J.;
- Greenhaff, Paul L.;
- Smith, Kenneth;
- Atherton, Philip J.
Publication type:
Article
Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2024, v. 15, n. 2, p. 603, doi. 10.1002/jcsm.13431
By:
- Shur, Natalie F.;
- Simpson, Elizabeth J.;
- Crossland, Hannah;
- Constantin, Despina;
- Cordon, Sally M.;
- Constantin‐Teodosiu, Dumitru;
- Stephens, Francis B.;
- Brook, Matthew S.;
- Atherton, Philip J.;
- Smith, Kenneth;
- Wilkinson, Daniel J.;
- Mougin, Olivier E.;
- Bradley, Christopher;
- Macdonald, Ian A.;
- Greenhaff, Paul L.
Publication type:
Article
Declines in muscle protein synthesis account for short‐term muscle disuse atrophy in humans in the absence of increased muscle protein breakdown.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2022, v. 13, n. 4, p. 2005, doi. 10.1002/jcsm.13005
By:
- Brook, Matthew S.;
- Stokes, Tanner;
- Gorissen, Stefan H.M.;
- Bass, Joseph J.;
- McGlory, Chris;
- Cegielski, Jessica;
- Wilkinson, Daniel J.;
- Phillips, Bethan E.;
- Smith, Ken;
- Phillips, Stuart M.;
- Atherton, Philip J.
Publication type:
Article
Pharmacological hypogonadism impairs molecular transducers of exercise‐induced muscle growth in humans.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2022, v. 13, n. 2, p. 1134, doi. 10.1002/jcsm.12843
By:
- Gharahdaghi, Nima;
- Rudrappa, Supreeth;
- Brook, Matthew S.;
- Farrash, Wesam;
- Idris, Iskandar;
- Aziz, Muhammad Hariz Abdul;
- Kadi, Fawzi;
- Papaioannou, Konstantinos;
- Phillips, Bethan E.;
- Sian, Tanvir;
- Herrod, Philip J.;
- Wilkinson, Daniel J.;
- Szewczyk, Nathaniel J.;
- Smith, Kenneth;
- Atherton, Philip J.
Publication type:
Article
The physiological impact of high‐intensity interval training in octogenarians with comorbidities.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2021, v. 12, n. 4, p. 866, doi. 10.1002/jcsm.12724
By:
- Blackwell, James E.M.;
- Gharahdaghi, Nima;
- Brook, Matthew S.;
- Watanabe, Shinya;
- Boereboom, Catherine L.;
- Doleman, Brett;
- Lund, Jonathan N.;
- Wilkinson, Daniel J.;
- Smith, Kenneth;
- Atherton, Philip J.;
- Williams, John P.;
- Phillips, Bethan E.
Publication type:
Article
The effect of short‐term exercise prehabilitation on skeletal muscle protein synthesis and atrophy during bed rest in older men.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2021, v. 12, n. 1, p. 52, doi. 10.1002/jcsm.12661
By:
- Smeuninx, Benoit;
- Elhassan, Yasir S.;
- Manolopoulos, Konstantinos N.;
- Sapey, Elizabeth;
- Rushton, Alison B.;
- Edwards, Sophie J.;
- Morgan, Paul T.;
- Philp, Andrew;
- Brook, Matthew S.;
- Gharahdaghi, Nima;
- Smith, Kenneth;
- Atherton, Philip J.;
- Breen, Leigh
Publication type:
Article
Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2019, v. 10, n. 6, p. 1276, doi. 10.1002/jcsm.12472
By:
- Gharahdaghi, Nima;
- Rudrappa, Supreeth;
- Brook, Matthew S.;
- Idris, Iskandar;
- Crossland, Hannah;
- Hamrock, Claire;
- Abdul Aziz, Muhammad Hariz;
- Kadi, Fawzi;
- Tarum, Janelle;
- Greenhaff, Paul L.;
- Constantin‐Teodosiu, Dumitru;
- Cegielski, Jessica;
- Phillips, Bethan E.;
- Wilkinson, Daniel J.;
- Szewczyk, Nathaniel J.;
- Smith, Kenneth;
- Atherton, Philip J.
Publication type:
Article
Effects of High-Volume Versus High-Load Resistance Training on Skeletal Muscle Growth and Molecular Adaptations.
Published in:
Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.857555
By:
- Vann, Christopher G.;
- Sexton, Casey L.;
- Osburn, Shelby C.;
- Smith, Morgan A.;
- Haun, Cody T.;
- Rumbley, Melissa N.;
- Mumford, Petey W.;
- Montgomery, Nathan T.;
- Ruple, Bradley A.;
- McKendry, James;
- Mcleod, Jonathan;
- Bashir, Adil;
- Beyers, Ronald J.;
- Brook, Matthew S.;
- Smith, Kenneth;
- Atherton, Philip J.;
- Beck, Darren T.;
- McDonald, James R.;
- Young, Kaelin C.;
- Phillips, Stuart M.
Publication type:
Article
The Effect of Whey Protein Supplementation on Myofibrillar Protein Synthesis and Performance Recovery in Resistance-Trained Men.
Published in:
Nutrients, 2020, v. 12, n. 3, p. 845, doi. 10.3390/nu12030845
By:
- Davies, Robert W.;
- Bass, Joseph J.;
- Carson, Brian P.;
- Norton, Catherine;
- Kozior, Marta;
- Wilkinson, Daniel J.;
- Brook, Matthew S.;
- Atherton, Philip J.;
- Smith, Ken;
- Jakeman, Philip M.
Publication type:
Article
Differential Stimulation of Post-Exercise Myofibrillar Protein Synthesis in Humans Following Isonitrogenous, Isocaloric Pre-Exercise Feeding.
Published in:
Nutrients, 2019, v. 11, n. 7, p. 1657, doi. 10.3390/nu11071657
By:
- Davies, Robert W.;
- Bass, Joseph J.;
- Carson, Brian P.;
- Norton, Catherine;
- Kozior, Marta;
- Amigo-Benavent, Miryam;
- Wilkinson, Daniel J.;
- Brook, Matthew S.;
- Atherton, Philip J.;
- Smith, Kenneth;
- Jakeman, Philip M.
Publication type:
Article

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