Works by Brons, Stephan

Results: 47

A Beam Monitor for Ion Beam Therapy Based on HV-CMOS Pixel Detectors.

Published in:

Instruments (2410-390X), 2023, v. 7, n. 1, p. 9, doi. 10.3390/instruments7010009

By:

Dierlamm, Alexander;
Balzer, Matthias;
Ehrler, Felix;
Husemann, Ulrich;
Koppenhöfer, Roland;
Perić, Ivan;
Pittermann, Martin;
Topko, Bogdan;
Weber, Alena;
Brons, Stephan;
Debus, Jürgen;
Grau, Nicole;
Hansmann, Thomas;
Jäkel, Oliver;
Klüter, Sebastian;
Naumann, Jakob

Publication type:

Article

Late normal tissue response in the rat spinal cord after carbon ion irradiation.

Published in:

2018

By:

Saager, Maria;
Peschke, Peter;
Welzel, Thomas;
Huang, Lifi;
Brons, Stephan;
Grün, Rebecca;
Scholz, Michael;
Debus, Jürgen;
Karger, Christian P.

Publication type:

journal article

Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation.

Published in:

2017

By:

Klein, Carmen;
Dokic, Ivana;
Mairani, Andrea;
Mein, Stewart;
Brons, Stephan;
Häring, Peter;
Haberer, Thomas;
Jäkel, Oliver;
Zimmermann, Astrid;
Zenke, Frank;
Blaukat, Andree;
Debus, Jürgen;
Abdollahi, Amir

Publication type:

journal article

Carbon ion radiotherapy: impact of tumor differentiation on local control in experimental prostate carcinomas.

Published in:

2017

By:

Glowa, Christin;
Peschke, Peter;
Brons, Stephan;
Neels, Oliver C.;
Kopka, Klaus;
Debu, Jürgen;
Karger, Christian P.;
Debus, Jürgen

Publication type:

journal article

Dataset for predicting single-spot proton ranges in proton therapy of prostate cancer.

Published in:

Scientific Data, 2021, v. 8, n. 1, p. 1, doi. 10.1038/s41597-021-01028-0

By:

Freitas, Hugo;
Magalhaes Martins, Paulo;
Tessonnier, Thomas;
Ackermann, Benjamin;
Brons, Stephan;
Seco, Joao

Publication type:

Article

Out‐of‐field neutron radiation from clinical proton, helium, carbon, and oxygen ion beams.

Published in:

Medical Physics, 2025, v. 52, n. 6, p. 4924, doi. 10.1002/mp.17797

By:

Bolzonella, Matteo;
Caresana, Marco;
Cirillo, Andrea;
Martí‐Climent, Josep M.;
Martínez‐Francés, Evangelina;
Mooshammer, Christina;
Schmidt, Stefan;
Brons, Stephan;
Silari, Marco;
Stengl, Christina;
Stolarczyk, Liliana;
Vedelago, José

Publication type:

Article

Accuracy of a helium‐beam radiography system based on thin pixel detectors for an anthropomorphic head phantom.

Published in:

Medical Physics, 2025, v. 52, n. 6, p. 4757, doi. 10.1002/mp.17786

By:

Metzner, Margareta;
Longarino, Friderike K.;
Ackermann, Benjamin;
Schlechter, Annika;
Saphörster, Maike;
Xu, Yanting;
Schlecker, Julian;
Wohlfahrt, Patrick;
Richter, Christian;
Brons, Stephan;
Debus, Jürgen;
Jäkel, Oliver;
Martišíková, Mária;
Gehrke, Tim

Publication type:

Article

Oxygen consumption measurements at ultra‐high dose rate over a wide LET range.

Published in:

Medical Physics, 2025, v. 52, n. 2, p. 1323, doi. 10.1002/mp.17496

By:

Karle, Celine;
Liew, Hans;
Tessonnier, Thomas;
Mein, Stewart;
Petersson, Kristoffer;
Schömers, Christian;
Scheloske, Stefan;
Brons, Stephan;
Cee, Rainer;
Major, Gerald;
Haberer, Thomas;
Abdollahi, Amir;
Debus, Jürgen;
Dokic, Ivana;
Mairani, Andrea

Publication type:

Article

An essentially radiation‐transparent body coil integrated with a patient rotation system for MR‐guided particle therapy.

Published in:

Medical Physics, 2024, v. 51, n. 6, p. 4028, doi. 10.1002/mp.17065

By:

Dietrich, Kilian A.;
Klüter, Sebastian;
Dinkel, Fabian;
Echner, Gernot;
Brons, Stephan;
Orzada, Stephan;
Debus, Jürgen;
Ladd, Mark E.;
Platt, Tanja

Publication type:

Article

Proton beam dosimetry in the presence of magnetic fields using Farmer‐type ionization chambers of different radii.

Published in:

Medical Physics, 2023, v. 50, n. 7, p. 4590, doi. 10.1002/mp.16368

By:

Marot, Mathieu;
Surla, Sonja;
Burke, Elisa;
Brons, Stephan;
Runz, Armin;
Greilich, Steffen;
Karger, Christian P.;
Jäkel, Oliver;
Burigo, Lucas N.

Publication type:

Article

Sensitivity correction of fluorescent nuclear track detectors using alpha particles: Determining LET spectra of light ions with enhanced accuracy.

Published in:

Medical Physics, 2023, v. 50, n. 4, p. 2385, doi. 10.1002/mp.16083

By:

Muñoz, Iván D.;
Burigo, Lucas N.;
Gehrke, Tim;
Brons, Stephan;
Greilich, Steffen;
Jäkel, Oliver

Publication type:

Article

Experimental comparison of photon versus particle computed tomography to predict tissue relative stopping powers.

Published in:

Medical Physics, 2022, v. 49, n. 1, p. 474, doi. 10.1002/mp.15283

By:

Bär, Esther;
Volz, Lennart;
Collins‐Fekete, Charles‐Antoine;
Brons, Stephan;
Runz, Armin;
Schulte, Reinhard Wilhelm;
Seco, Joao

Publication type:

Article

Quality assurance method for monitoring of lateral pencil beam positions in scanned carbon‐ion radiotherapy using tracking of secondary ions.

Published in:

Medical Physics, 2021, v. 48, n. 8, p. 4411, doi. 10.1002/mp.15018

By:

Félix‐Bautista, Renato;
Ghesquière‐Diérickx, Laura;
Marek, Lukáš;
Granja, Carlos;
Soukup, Pavel;
Turecek, Daniel;
Kelleter, Laurent;
Brons, Stephan;
Ellerbrock, Malte;
Jäkel, Oliver;
Gehrke, Tim;
Martišíková, Mária

Publication type:

Article

Does FLASH deplete oxygen? Experimental evaluation for photons, protons, and carbon ions.

Published in:

Medical Physics, 2021, v. 48, n. 7, p. 3982, doi. 10.1002/mp.14917

By:

Jansen, Jeannette;
Knoll, Jan;
Beyreuther, Elke;
Pawelke, Jörg;
Skuza, Raphael;
Hanley, Rachel;
Brons, Stephan;
Pagliari, Francesca;
Seco, Joao

Publication type:

Article

Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams.

Published in:

Medical Physics, 2017, v. 44, n. 11, p. 6061, doi. 10.1002/mp.12568

By:

Patel, Darshana;
Bronk, Lawrence;
Guan, Fada;
Peeler, Christopher R.;
Brons, Stephan;
Dokic, Ivana;
Abdollahi, Amir;
Rittmüller, Claudia;
Jäkel, Oliver;
Grosshans, David;
Mohan, Radhe;
Titt, Uwe

Publication type:

Article

Carbon and oxygen minibeam radiation therapy: An experimental dosimetric evaluation.

Published in:

Medical Physics, 2017, v. 44, n. 8, p. 4223, doi. 10.1002/mp.12383

By:

Martínez-Rovira, Immaculada;
González, Wilfredo;
Brons, Stephan;
Prezado, Yolanda

Publication type:

Article

Optimization of Carbon Ion Treatment Plans by Integrating Tissue Specific α/β-Values for Patients with Non-Resectable Pancreatic Cancer.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164473

By:

Dreher, Constantin;
Scholz, Christian;
Pommer, Mira;
Brons, Stephan;
Prokesch, Hannah;
Ecker, Swantje;
Debus, Jürgen;
Jäkel, Oliver;
Combs, Stephanie E.;
Habermehl, Daniel

Publication type:

Article

Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.

Published in:

Neuro-Oncology, 2021, v. 23, n. 12, p. 2028, doi. 10.1093/neuonc/noab127

By:

Simovic, Milena;
Bolkestein, Michiel;
Moustafa, Mahmoud;
Wong, John K L;
Körber, Verena;
Benedetto, Sarah;
Khalid, Umar;
Schreiber, Hannah Sophia;
Jugold, Manfred;
Korshunov, Andrey;
Hübschmann, Daniel;
Mack, Norman;
Brons, Stephan;
Wei, Pei-Chi;
Breckwoldt, Michael O;
Heiland, Sabine;
Bendszus, Martin;
Debus, Jürgen;
Höfer, Thomas;
Zapatka, Marc

Publication type:

Article

Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids.

Published in:

Cancers, 2020, v. 12, n. 2, p. 469, doi. 10.3390/cancers12020469

By:

Nowrouzi, Ali;
Sertorio, Mathieu G.;
Akbarpour, Mahdi;
Knoll, Maximillian;
Krunic, Damir;
Kuhar, Matthew;
Schwager, Christian;
Brons, Stephan;
Debus, Jürgen;
Wells, Susanne I.;
Wells, James M.;
Abdollahi, Amir

Publication type:

Article

Fractionated carbon ion irradiations of the rat spinal cord: comparison of the relative biological effectiveness with predictions of the local effect model.

Published in:

2020

By:

Saager, Maria;
Glowa, Christin;
Peschke, Peter;
Brons, Stephan;
Grün, Rebecca;
Scholz, Michael;
Debus, Jürgen;
Karger, Christian P.

Publication type:

journal article

Experimental Comparison of Fiducial Markers Used in Proton Therapy: Study of Different Imaging Modalities and Proton Fluence Perturbations Measured With CMOS Pixel Sensors.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.830080

By:

Reidel, Claire-Anne;
Horst, Felix;
Schuy, Christoph;
Jäkel, Oliver;
Ecker, Swantje;
Henkner, Katrin;
Brons, Stephan;
Durante, Marco;
Weber, Uli

Publication type:

Article

Integrin-based meningioma cell migration is promoted by photon but not by carbon-ion irradiation.

Published in:

Strahlentherapie und Onkologie, 2015, v. 191, n. 4, p. 347, doi. 10.1007/s00066-014-0778-y

By:

Simon, Florian;
Dittmar, Jan-Oliver;
Brons, Stephan;
Orschiedt, Lena;
Urbschat, Steffi;
Weber, Klaus-Josef;
Debus, Jürgen;
Combs, Stephanie E.;
Rieken, Stefan

Publication type:

Article

Helium ions for radiotherapy? Physical and biological verifications of a novel treatment modality.

Published in:

Medical Physics, 2016, v. 43, n. 4, p. 1995, doi. 10.1118/1.4944593

By:

Krämer, Michael;
Scifoni, Emanuele;
Schuy, Christoph;
Rovituso, Marta;
Tinganelli, Walter;
Maier, Andreas;
Kaderka, Robert;
Kraft‐Weyrather, Wilma;
Brons, Stephan;
Tessonnier, Thomas;
Parodi, Katia;
Durante, Marco

Publication type:

Article

High resistance to X-rays and therapeutic carbon ions in glioblastoma cells bearing dysfunctional ATM associates with intrinsic chromosomal instability.

Published in:

International Journal of Radiation Biology, 2015, v. 91, n. 2, p. 157, doi. 10.3109/09553002.2014.937511

By:

Dokic, Ivana;
Mairani, Andrea;
Brons, Stephan;
Schoell, Brigitte;
Jauch, Anna;
Krunic, Damir;
Debus, Jürgen;
Régnier-Vigouroux, Anne;
Weber, Klaus-Josef

Publication type:

Article

Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation.

Published in:

International Journal of Radiation Biology, 2013, v. 89, n. 10, p. 782, doi. 10.3109/09553002.2013.800247

By:

Mairani, Andrea;
Böhlen, Till T.;
Dokic, Ivana;
Cabal, Gonzalo;
Brons, Stephan;
Haberer, Thomas

Publication type:

Article

Temozolomide in combination with carbon ion or photon irradiation in glioblastoma multiforme cell lines - does scheduling matter?

Published in:

International Journal of Radiation Biology, 2013, v. 89, n. 9, p. 692, doi. 10.3109/09553002.2013.791406

By:

Harrabi, Semi;
Combs, Stephanie E.;
Brons, Stephan;
Haberer, Thomas;
Debus, Jürgen;
Weber, Klaus-Josef

Publication type:

Article

Evaluation of Helium Ion Radiotherapy in Combination with Gemcitabine in Pancreatic Cancer In Vitro.

Published in:

Cancers, 2024, v. 16, n. 8, p. 1497, doi. 10.3390/cancers16081497

By:

Cepni, Bahar;
Tessonnier, Thomas;
Dokic, Ivana;
Brons, Stephan;
Tawk, Bouchra;
Mairani, Andrea;
Abdollahi, Amir;
Debus, Jürgen;
Herfarth, Klaus;
Liermann, Jakob

Publication type:

Article

Absorbed dose in ion beams: comparison of ionisation- and fluence-based measurements.

Published in:

Radiation Protection Dosimetry, 2014, v. 161, n. 1-4, p. 387, doi. 10.1093/rpd/ncu004

By:

Osinga, Julia-Maria;
Brons, Stephan;
Bartz, James A.;
Akselrod, Mark S.;
Jäkel, Oliver;
Greilich, Steffen

Publication type:

Article

Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-78577-8

By:

Hartmann, Laura;
Schröter, Philipp;
Osen, Wolfram;
Baumann, Daniel;
Offringa, Rienk;
Moustafa, Mahmoud;
Will, Rainer;
Debus, Jürgen;
Brons, Stephan;
Rieken, Stefan;
Eichmüller, Stefan B.

Publication type:

Article

PIBS: Proton and ion beam spectroscopy for in vivo measurements of oxygen, carbon, and calcium concentrations in the human body.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63215-0

By:

Magalhaes Martins, Paulo;
Dal Bello, Riccardo;
Ackermann, Benjamin;
Brons, Stephan;
Hermann, German;
Kihm, Thomas;
Seco, Joao

Publication type:

Article

Combination of Photon and Carbon lon Irradiation with Targeted Therapy Substance Temsirolimus and Gemctabine in Hepatocelluar Carcinoma Cell Lines.

Published in:

Frontiers in Oncology, 2017, v. 7, p. 1, doi. 10.3389/fonc.2017.00035

By:

Dehne, Sarah;
Fritz, Clarissa;
Rieken, Stefan;
Baris, Daniela;
Brons, Stephan;
Haberer, Thomas;
Debus, Jürgen;
Weber, Klaus-Josef;
Schmid, Thomas E.;
Combs, Stephanie E.;
Habermehl, Daniel

Publication type:

Article

Phase Space Generation for Proton and Carbon Ion Beams for External Users' Applications at the Heidelberg Ion Therapy Center.

Published in:

Frontiers in Oncology, 2016, v. 5, p. 1, doi. 10.3389/fonc.2015.00297

By:

Tessonnier, Thomas;
Marcelos, Tiago;
Mairani, Andrea;
Brons, Stephan;
Parodi, Katia

Publication type:

Article

The Relative Biological Effectiveness for Carbon and Oxygen Ion Beams Using the Raster-Scanning Technique in Hepatocellular Carcinoma Cell Lines.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0113591

By:

Habermehl, Daniel;
Ilicic, Katarina;
Dehne, Sarah;
Rieken, Stefan;
Orschiedt, Lena;
Brons, Stephan;
Haberer, Thomas;
Weber, Klaus-Josef;
Debus, Jürgen;
Combs, Stephanie E.

Publication type:

Article

Towards real-time PGS range monitoring in proton therapy of prostate cancer.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-93612-y

By:

Magalhaes Martins, Paulo;
Freitas, Hugo;
Tessonnier, Thomas;
Ackermann, Benjamin;
Brons, Stephan;
Seco, Joao

Publication type:

Article

Optimization of carbon ion and proton treatment plans using the raster-scanning technique for patients with unresectable pancreatic cancer.

Published in:

2015

By:

Dreher, Constantin;
Habermehl, Daniel;
Ecker, Swantje;
Brons, Stephan;
El-Shafie, Rami;
Jäkel, Oliver;
Debus, Jürgen;
Combs, Stephanie E.

Publication type:

journal article

Ion therapy of prostate cancer: daily rectal dose reduction by application of spacer gel.

Published in:

Radiation Oncology, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13014-015-0348-1

By:

Rucinski, Antoni;
Brons, Stephan;
Richter, Daniel;
Habl, Gregor;
Debus, Jürgen;
Bert, Christoph;
Haberer, Thomas;
Jäkel, Oliver

Publication type:

Article

Comparison of the effects of photon versus carbon ion irradiation when combined with chemotherapy in vitro.

Published in:

Radiation Oncology, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1748-717X-8-260

By:

Schlaich, Fabian;
Brons, Stephan;
Haberer, Thomas;
Debus, Jürgen;
Combs, Stephanie E.;
Weber, Klaus-Josef

Publication type:

Article

Preclinical investigations towards the first spacer gel application in prostate cancer treatment during particle therapy at HIT.

Published in:

Radiation Oncology, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1748-717X-8-134

By:

Ruciński, Antoni;
Bauer, Julia;
Campbell, Patrick;
Brons, Stephan;
Unholtz, Daniel;
Habl, Gregor;
Herfarth, Klaus;
Debus, Jürgen;
Bert, Christoph;
Parodi, Katia;
Jäkel, Oliver;
Haberer, Thomas

Publication type:

Article

Hypofractionated carbon ion therapy delivered with scanned ion beams for patients with hepatocellular carcinoma - feasibility and clinical response.

Published in:

Radiation Oncology, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1748-717X-8-59

By:

Habermehl, Daniel;
Debus, Jürgen;
Ganten, Tom;
Ganten, Maria-Katharina;
Bauer, Julia;
Brecht, Ingo C.;
Brons, Stephan;
Haberer, Thomas;
Haertig, Martin;
Jäkel, Oliver;
Parodi, Katia;
Welzel, Thomas;
Combs, Stephanie E.

Publication type:

Article

Hypofractionated carbon ion therapy delivered with scanned ion beams for patients with hepatocellular carcinoma - feasibility and clinical response.

Published in:

2013

By:

Habermehl, Daniel;
Debus, Jürgen;
Ganten, Tom;
Ganten, Maria-Katharina;
Bauer, Julia;
Brecht, Ingo C;
Brons, Stephan;
Haberer, Thomas;
Haertig, Martin;
Jäkel, Oliver;
Parodi, Katia;
Welzel, Thomas;
Combs, Stephanie E

Publication type:

journal article

Comparison of the effects of photon versus carbon ion irradiation when combined with chemotherapy in vitro.

Published in:

2013

By:

Schlaich, Fabian;
Brons, Stephan;
Haberer, Thomas;
Debus, Jürgen;
Combs, Stephanie E;
Weber, Klaus-Josef

Publication type:

journal article

Preclinical investigations towards the first spacer gel application in prostate cancer treatment during particle therapy at HIT.

Published in:

2013

By:

Rucinski, Antoni;
Bauer, Julia;
Campbell, Patrick;
Brons, Stephan;
Unholtz, Daniel;
Habl, Gregor;
Herfarth, Klaus;
Debus, Jürgen;
Bert, Christoph;
Parodi, Katia;
Jäkel, Oliver;
Haberer, Thomas;
Ruciński, Antoni

Publication type:

journal article

Identification of stable endogenous control genes for transcriptional profiling of photon, proton and carbon-ion irradiated cells.

Published in:

2012

By:

Sharungbam, Geeta D;
Schwager, Christian;
Chiblak, Sara;
Brons, Stephan;
Hlatky, Lynn;
Haberer, Thomas;
Debus, Jürgen;
Abdollahi, Amir

Publication type:

journal article

Identification of stable endogenous control genes for transcriptional profiling of photon, proton and carbon-ion irradiated cells.

Published in:

Radiation Oncology, 2012, v. 7, n. 1, p. 70, doi. 10.1186/1748-717X-7-70

By:

Sharungbam, Geeta D.;
Schwager, Christian;
Chiblak, Sara;
Brons, Stephan;
Hlatky, Lynn;
Haberer, Thomas;
Debus, J�rgen;
Abdollahi, Amir

Publication type:

Article

The relative biological effectiveness of carbon ion irradiations of the rat spinal cord increases linearly with LET up to 99 keV/μm.

Published in:

Acta Oncologica, 2016, v. 55, n. 12, p. 1512, doi. 10.1080/0284186X.2016.1250947

By:

Saager, Maria;
Glowa, Christin;
Peschke, Peter;
Brons, Stephan;
Grün, Rebecca;
Scholz, Michael;
Huber, Peter E.;
Debus, Jürgen;
Karger, Christian P.

Publication type:

Article

Ramipril reduces incidence and prolongates latency time of radiation-induced rat myelopathy after photon and carbon ion irradiation.

Published in:

Journal of Radiation Research, 2020, v. 61, n. 5, p. 791, doi. 10.1093/jrr/rraa042

By:

Saager, Maria;
Hahn, Eric W;
Peschke, Peter;
Brons, Stephan;
Huber, Peter E;
Debus, Jürgen;
Karger, Christian P

Publication type:

Article

Carbon-ion irradiation overcomes HPV-integration/E2 gene-disruption induced radioresistance of cervical keratinocytes.

Published in:

Journal of Radiation Research, 2019, v. 60, n. 5, p. 564, doi. 10.1093/jrr/rrz048

By:

Arians, Nathalie;
Nicolay, Nils Henrik;
Brons, Stephan;
Koerber, Stefan Alexander;
Jaschke, Christine;
Vercruysse, Marco;
Daffinger, Sigrid;
Rühle, Alexander;
Debus, Jürgen;
Lindel, Katja

Publication type:

Article