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High resistance to X-rays and therapeutic carbon ions in glioblastoma cells bearing dysfunctional ATM associates with intrinsic chromosomal instability.
Published in:
International Journal of Radiation Biology, 2015, v. 91, n. 2, p. 157, doi. 10.3109/09553002.2014.937511
By:
- Dokic, Ivana;
- Mairani, Andrea;
- Brons, Stephan;
- Schoell, Brigitte;
- Jauch, Anna;
- Krunic, Damir;
- Debus, Jürgen;
- Régnier-Vigouroux, Anne;
- Weber, Klaus-Josef
Publication type:
Article
Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation.
Published in:
International Journal of Radiation Biology, 2013, v. 89, n. 10, p. 782, doi. 10.3109/09553002.2013.800247
By:
- Mairani, Andrea;
- Böhlen, Till T.;
- Dokic, Ivana;
- Cabal, Gonzalo;
- Brons, Stephan;
- Haberer, Thomas
Publication type:
Article
Temozolomide in combination with carbon ion or photon irradiation in glioblastoma multiforme cell lines - does scheduling matter?
Published in:
International Journal of Radiation Biology, 2013, v. 89, n. 9, p. 692, doi. 10.3109/09553002.2013.791406
By:
- Harrabi, Semi;
- Combs, Stephanie E.;
- Brons, Stephan;
- Haberer, Thomas;
- Debus, Jürgen;
- Weber, Klaus-Josef
Publication type:
Article
Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.
Published in:
Neuro-Oncology, 2021, v. 23, n. 12, p. 2028, doi. 10.1093/neuonc/noab127
By:
- Simovic, Milena;
- Bolkestein, Michiel;
- Moustafa, Mahmoud;
- Wong, John K L;
- Körber, Verena;
- Benedetto, Sarah;
- Khalid, Umar;
- Schreiber, Hannah Sophia;
- Jugold, Manfred;
- Korshunov, Andrey;
- Hübschmann, Daniel;
- Mack, Norman;
- Brons, Stephan;
- Wei, Pei-Chi;
- Breckwoldt, Michael O;
- Heiland, Sabine;
- Bendszus, Martin;
- Debus, Jürgen;
- Höfer, Thomas;
- Zapatka, Marc
Publication type:
Article
Late normal tissue response in the rat spinal cord after carbon ion irradiation.
Published in:
2018
By:
- Saager, Maria;
- Peschke, Peter;
- Welzel, Thomas;
- Huang, Lifi;
- Brons, Stephan;
- Grün, Rebecca;
- Scholz, Michael;
- Debus, Jürgen;
- Karger, Christian P.
Publication type:
journal article
Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation.
Published in:
2017
By:
- Klein, Carmen;
- Dokic, Ivana;
- Mairani, Andrea;
- Mein, Stewart;
- Brons, Stephan;
- Häring, Peter;
- Haberer, Thomas;
- Jäkel, Oliver;
- Zimmermann, Astrid;
- Zenke, Frank;
- Blaukat, Andree;
- Debus, Jürgen;
- Abdollahi, Amir
Publication type:
journal article
Carbon ion radiotherapy: impact of tumor differentiation on local control in experimental prostate carcinomas.
Published in:
2017
By:
- Glowa, Christin;
- Peschke, Peter;
- Brons, Stephan;
- Neels, Oliver C.;
- Kopka, Klaus;
- Debu, Jürgen;
- Karger, Christian P.;
- Debus, Jürgen
Publication type:
journal article
Phase Space Generation for Proton and Carbon Ion Beams for External Users' Applications at the Heidelberg Ion Therapy Center.
Published in:
Frontiers in Oncology, 2016, v. 5, p. 1, doi. 10.3389/fonc.2015.00297
By:
- Tessonnier, Thomas;
- Marcelos, Tiago;
- Mairani, Andrea;
- Brons, Stephan;
- Parodi, Katia
Publication type:
Article
Ramipril reduces incidence and prolongates latency time of radiation-induced rat myelopathy after photon and carbon ion irradiation.
Published in:
Journal of Radiation Research, 2020, v. 61, n. 5, p. 791, doi. 10.1093/jrr/rraa042
By:
- Saager, Maria;
- Hahn, Eric W;
- Peschke, Peter;
- Brons, Stephan;
- Huber, Peter E;
- Debus, Jürgen;
- Karger, Christian P
Publication type:
Article
Carbon-ion irradiation overcomes HPV-integration/E2 gene-disruption induced radioresistance of cervical keratinocytes.
Published in:
Journal of Radiation Research, 2019, v. 60, n. 5, p. 564, doi. 10.1093/jrr/rrz048
By:
- Arians, Nathalie;
- Nicolay, Nils Henrik;
- Brons, Stephan;
- Koerber, Stefan Alexander;
- Jaschke, Christine;
- Vercruysse, Marco;
- Daffinger, Sigrid;
- Rühle, Alexander;
- Debus, Jürgen;
- Lindel, Katja
Publication type:
Article
Integrin-based meningioma cell migration is promoted by photon but not by carbon-ion irradiation.
Published in:
Strahlentherapie und Onkologie, 2015, v. 191, n. 4, p. 347, doi. 10.1007/s00066-014-0778-y
By:
- Simon, Florian;
- Dittmar, Jan-Oliver;
- Brons, Stephan;
- Orschiedt, Lena;
- Urbschat, Steffi;
- Weber, Klaus-Josef;
- Debus, Jürgen;
- Combs, Stephanie E.;
- Rieken, Stefan
Publication type:
Article
A Beam Monitor for Ion Beam Therapy Based on HV-CMOS Pixel Detectors.
Published in:
Instruments (2410-390X), 2023, v. 7, n. 1, p. 9, doi. 10.3390/instruments7010009
By:
- Dierlamm, Alexander;
- Balzer, Matthias;
- Ehrler, Felix;
- Husemann, Ulrich;
- Koppenhöfer, Roland;
- Perić, Ivan;
- Pittermann, Martin;
- Topko, Bogdan;
- Weber, Alena;
- Brons, Stephan;
- Debus, Jürgen;
- Grau, Nicole;
- Hansmann, Thomas;
- Jäkel, Oliver;
- Klüter, Sebastian;
- Naumann, Jakob
Publication type:
Article
Towards real-time PGS range monitoring in proton therapy of prostate cancer.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-93612-y
By:
- Magalhaes Martins, Paulo;
- Freitas, Hugo;
- Tessonnier, Thomas;
- Ackermann, Benjamin;
- Brons, Stephan;
- Seco, Joao
Publication type:
Article
Evaluation of Helium Ion Radiotherapy in Combination with Gemcitabine in Pancreatic Cancer In Vitro.
Published in:
Cancers, 2024, v. 16, n. 8, p. 1497, doi. 10.3390/cancers16081497
By:
- Cepni, Bahar;
- Tessonnier, Thomas;
- Dokic, Ivana;
- Brons, Stephan;
- Tawk, Bouchra;
- Mairani, Andrea;
- Abdollahi, Amir;
- Debus, Jürgen;
- Herfarth, Klaus;
- Liermann, Jakob
Publication type:
Article
Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids.
Published in:
Cancers, 2020, v. 12, n. 2, p. 469, doi. 10.3390/cancers12020469
By:
- Nowrouzi, Ali;
- Sertorio, Mathieu G.;
- Akbarpour, Mahdi;
- Knoll, Maximillian;
- Krunic, Damir;
- Kuhar, Matthew;
- Schwager, Christian;
- Brons, Stephan;
- Debus, Jürgen;
- Wells, Susanne I.;
- Wells, James M.;
- Abdollahi, Amir
Publication type:
Article
Fractionated carbon ion irradiations of the rat spinal cord: comparison of the relative biological effectiveness with predictions of the local effect model.
Published in:
2020
By:
- Saager, Maria;
- Glowa, Christin;
- Peschke, Peter;
- Brons, Stephan;
- Grün, Rebecca;
- Scholz, Michael;
- Debus, Jürgen;
- Karger, Christian P.
Publication type:
journal article
The Relative Biological Effectiveness for Carbon and Oxygen Ion Beams Using the Raster-Scanning Technique in Hepatocellular Carcinoma Cell Lines.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0113591
By:
- Habermehl, Daniel;
- Ilicic, Katarina;
- Dehne, Sarah;
- Rieken, Stefan;
- Orschiedt, Lena;
- Brons, Stephan;
- Haberer, Thomas;
- Weber, Klaus-Josef;
- Debus, Jürgen;
- Combs, Stephanie E.
Publication type:
Article
Optimization of carbon ion and proton treatment plans using the raster-scanning technique for patients with unresectable pancreatic cancer.
Published in:
2015
By:
- Dreher, Constantin;
- Habermehl, Daniel;
- Ecker, Swantje;
- Brons, Stephan;
- El-Shafie, Rami;
- Jäkel, Oliver;
- Debus, Jürgen;
- Combs, Stephanie E.
Publication type:
journal article
Ion therapy of prostate cancer: daily rectal dose reduction by application of spacer gel.
Published in:
Radiation Oncology, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13014-015-0348-1
By:
- Rucinski, Antoni;
- Brons, Stephan;
- Richter, Daniel;
- Habl, Gregor;
- Debus, Jürgen;
- Bert, Christoph;
- Haberer, Thomas;
- Jäkel, Oliver
Publication type:
Article
Comparison of the effects of photon versus carbon ion irradiation when combined with chemotherapy in vitro.
Published in:
Radiation Oncology, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1748-717X-8-260
By:
- Schlaich, Fabian;
- Brons, Stephan;
- Haberer, Thomas;
- Debus, Jürgen;
- Combs, Stephanie E.;
- Weber, Klaus-Josef
Publication type:
Article
Preclinical investigations towards the first spacer gel application in prostate cancer treatment during particle therapy at HIT.
Published in:
Radiation Oncology, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1748-717X-8-134
By:
- Ruciński, Antoni;
- Bauer, Julia;
- Campbell, Patrick;
- Brons, Stephan;
- Unholtz, Daniel;
- Habl, Gregor;
- Herfarth, Klaus;
- Debus, Jürgen;
- Bert, Christoph;
- Parodi, Katia;
- Jäkel, Oliver;
- Haberer, Thomas
Publication type:
Article
Hypofractionated carbon ion therapy delivered with scanned ion beams for patients with hepatocellular carcinoma - feasibility and clinical response.
Published in:
Radiation Oncology, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1748-717X-8-59
By:
- Habermehl, Daniel;
- Debus, Jürgen;
- Ganten, Tom;
- Ganten, Maria-Katharina;
- Bauer, Julia;
- Brecht, Ingo C.;
- Brons, Stephan;
- Haberer, Thomas;
- Haertig, Martin;
- Jäkel, Oliver;
- Parodi, Katia;
- Welzel, Thomas;
- Combs, Stephanie E.
Publication type:
Article
Hypofractionated carbon ion therapy delivered with scanned ion beams for patients with hepatocellular carcinoma - feasibility and clinical response.
Published in:
2013
By:
- Habermehl, Daniel;
- Debus, Jürgen;
- Ganten, Tom;
- Ganten, Maria-Katharina;
- Bauer, Julia;
- Brecht, Ingo C;
- Brons, Stephan;
- Haberer, Thomas;
- Haertig, Martin;
- Jäkel, Oliver;
- Parodi, Katia;
- Welzel, Thomas;
- Combs, Stephanie E
Publication type:
journal article
Comparison of the effects of photon versus carbon ion irradiation when combined with chemotherapy in vitro.
Published in:
2013
By:
- Schlaich, Fabian;
- Brons, Stephan;
- Haberer, Thomas;
- Debus, Jürgen;
- Combs, Stephanie E;
- Weber, Klaus-Josef
Publication type:
journal article
Preclinical investigations towards the first spacer gel application in prostate cancer treatment during particle therapy at HIT.
Published in:
2013
By:
- Rucinski, Antoni;
- Bauer, Julia;
- Campbell, Patrick;
- Brons, Stephan;
- Unholtz, Daniel;
- Habl, Gregor;
- Herfarth, Klaus;
- Debus, Jürgen;
- Bert, Christoph;
- Parodi, Katia;
- Jäkel, Oliver;
- Haberer, Thomas;
- Ruciński, Antoni
Publication type:
journal article
Identification of stable endogenous control genes for transcriptional profiling of photon, proton and carbon-ion irradiated cells.
Published in:
2012
By:
- Sharungbam, Geeta D;
- Schwager, Christian;
- Chiblak, Sara;
- Brons, Stephan;
- Hlatky, Lynn;
- Haberer, Thomas;
- Debus, Jürgen;
- Abdollahi, Amir
Publication type:
journal article
Identification of stable endogenous control genes for transcriptional profiling of photon, proton and carbon-ion irradiated cells.
Published in:
Radiation Oncology, 2012, v. 7, n. 1, p. 70, doi. 10.1186/1748-717X-7-70
By:
- Sharungbam, Geeta D.;
- Schwager, Christian;
- Chiblak, Sara;
- Brons, Stephan;
- Hlatky, Lynn;
- Haberer, Thomas;
- Debus, J�rgen;
- Abdollahi, Amir
Publication type:
Article
Dataset for predicting single-spot proton ranges in proton therapy of prostate cancer.
Published in:
Scientific Data, 2021, v. 8, n. 1, p. 1, doi. 10.1038/s41597-021-01028-0
By:
- Freitas, Hugo;
- Magalhaes Martins, Paulo;
- Tessonnier, Thomas;
- Ackermann, Benjamin;
- Brons, Stephan;
- Seco, Joao
Publication type:
Article
Combination of Photon and Carbon lon Irradiation with Targeted Therapy Substance Temsirolimus and Gemctabine in Hepatocelluar Carcinoma Cell Lines.
Published in:
Frontiers in Oncology, 2017, v. 7, p. 1, doi. 10.3389/fonc.2017.00035
By:
- Dehne, Sarah;
- Fritz, Clarissa;
- Rieken, Stefan;
- Baris, Daniela;
- Brons, Stephan;
- Haberer, Thomas;
- Debus, Jürgen;
- Weber, Klaus-Josef;
- Schmid, Thomas E.;
- Combs, Stephanie E.;
- Habermehl, Daniel
Publication type:
Article
Optimization of Carbon Ion Treatment Plans by Integrating Tissue Specific α/β-Values for Patients with Non-Resectable Pancreatic Cancer.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164473
By:
- Dreher, Constantin;
- Scholz, Christian;
- Pommer, Mira;
- Brons, Stephan;
- Prokesch, Hannah;
- Ecker, Swantje;
- Debus, Jürgen;
- Jäkel, Oliver;
- Combs, Stephanie E.;
- Habermehl, Daniel
Publication type:
Article
Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-78577-8
By:
- Hartmann, Laura;
- Schröter, Philipp;
- Osen, Wolfram;
- Baumann, Daniel;
- Offringa, Rienk;
- Moustafa, Mahmoud;
- Will, Rainer;
- Debus, Jürgen;
- Brons, Stephan;
- Rieken, Stefan;
- Eichmüller, Stefan B.
Publication type:
Article
PIBS: Proton and ion beam spectroscopy for in vivo measurements of oxygen, carbon, and calcium concentrations in the human body.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63215-0
By:
- Magalhaes Martins, Paulo;
- Dal Bello, Riccardo;
- Ackermann, Benjamin;
- Brons, Stephan;
- Hermann, German;
- Kihm, Thomas;
- Seco, Joao
Publication type:
Article
Experimental Comparison of Fiducial Markers Used in Proton Therapy: Study of Different Imaging Modalities and Proton Fluence Perturbations Measured With CMOS Pixel Sensors.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.830080
By:
- Reidel, Claire-Anne;
- Horst, Felix;
- Schuy, Christoph;
- Jäkel, Oliver;
- Ecker, Swantje;
- Henkner, Katrin;
- Brons, Stephan;
- Durante, Marco;
- Weber, Uli
Publication type:
Article
The relative biological effectiveness of carbon ion irradiations of the rat spinal cord increases linearly with LET up to 99 keV/μm.
Published in:
Acta Oncologica, 2016, v. 55, n. 12, p. 1512, doi. 10.1080/0284186X.2016.1250947
By:
- Saager, Maria;
- Glowa, Christin;
- Peschke, Peter;
- Brons, Stephan;
- Grün, Rebecca;
- Scholz, Michael;
- Huber, Peter E.;
- Debus, Jürgen;
- Karger, Christian P.
Publication type:
Article
Absorbed dose in ion beams: comparison of ionisation- and fluence-based measurements.
Published in:
Radiation Protection Dosimetry, 2014, v. 161, n. 1-4, p. 387, doi. 10.1093/rpd/ncu004
By:
- Osinga, Julia-Maria;
- Brons, Stephan;
- Bartz, James A.;
- Akselrod, Mark S.;
- Jäkel, Oliver;
- Greilich, Steffen
Publication type:
Article
An essentially radiation‐transparent body coil integrated with a patient rotation system for MR‐guided particle therapy.
Published in:
Medical Physics, 2024, v. 51, n. 6, p. 4028, doi. 10.1002/mp.17065
By:
- Dietrich, Kilian A.;
- Klüter, Sebastian;
- Dinkel, Fabian;
- Echner, Gernot;
- Brons, Stephan;
- Orzada, Stephan;
- Debus, Jürgen;
- Ladd, Mark E.;
- Platt, Tanja
Publication type:
Article
Proton beam dosimetry in the presence of magnetic fields using Farmer‐type ionization chambers of different radii.
Published in:
Medical Physics, 2023, v. 50, n. 7, p. 4590, doi. 10.1002/mp.16368
By:
- Marot, Mathieu;
- Surla, Sonja;
- Burke, Elisa;
- Brons, Stephan;
- Runz, Armin;
- Greilich, Steffen;
- Karger, Christian P.;
- Jäkel, Oliver;
- Burigo, Lucas N.
Publication type:
Article
Sensitivity correction of fluorescent nuclear track detectors using alpha particles: Determining LET spectra of light ions with enhanced accuracy.
Published in:
Medical Physics, 2023, v. 50, n. 4, p. 2385, doi. 10.1002/mp.16083
By:
- Muñoz, Iván D.;
- Burigo, Lucas N.;
- Gehrke, Tim;
- Brons, Stephan;
- Greilich, Steffen;
- Jäkel, Oliver
Publication type:
Article
Experimental comparison of photon versus particle computed tomography to predict tissue relative stopping powers.
Published in:
Medical Physics, 2022, v. 49, n. 1, p. 474, doi. 10.1002/mp.15283
By:
- Bär, Esther;
- Volz, Lennart;
- Collins‐Fekete, Charles‐Antoine;
- Brons, Stephan;
- Runz, Armin;
- Schulte, Reinhard Wilhelm;
- Seco, Joao
Publication type:
Article
Quality assurance method for monitoring of lateral pencil beam positions in scanned carbon‐ion radiotherapy using tracking of secondary ions.
Published in:
Medical Physics, 2021, v. 48, n. 8, p. 4411, doi. 10.1002/mp.15018
By:
- Félix‐Bautista, Renato;
- Ghesquière‐Diérickx, Laura;
- Marek, Lukáš;
- Granja, Carlos;
- Soukup, Pavel;
- Turecek, Daniel;
- Kelleter, Laurent;
- Brons, Stephan;
- Ellerbrock, Malte;
- Jäkel, Oliver;
- Gehrke, Tim;
- Martišíková, Mária
Publication type:
Article
Does FLASH deplete oxygen? Experimental evaluation for photons, protons, and carbon ions.
Published in:
Medical Physics, 2021, v. 48, n. 7, p. 3982, doi. 10.1002/mp.14917
By:
- Jansen, Jeannette;
- Knoll, Jan;
- Beyreuther, Elke;
- Pawelke, Jörg;
- Skuza, Raphael;
- Hanley, Rachel;
- Brons, Stephan;
- Pagliari, Francesca;
- Seco, Joao
Publication type:
Article
Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams.
Published in:
Medical Physics, 2017, v. 44, n. 11, p. 6061, doi. 10.1002/mp.12568
By:
- Patel, Darshana;
- Bronk, Lawrence;
- Guan, Fada;
- Peeler, Christopher R.;
- Brons, Stephan;
- Dokic, Ivana;
- Abdollahi, Amir;
- Rittmüller, Claudia;
- Jäkel, Oliver;
- Grosshans, David;
- Mohan, Radhe;
- Titt, Uwe
Publication type:
Article
Carbon and oxygen minibeam radiation therapy: An experimental dosimetric evaluation.
Published in:
Medical Physics, 2017, v. 44, n. 8, p. 4223, doi. 10.1002/mp.12383
By:
- Martínez-Rovira, Immaculada;
- González, Wilfredo;
- Brons, Stephan;
- Prezado, Yolanda
Publication type:
Article
Helium ions for radiotherapy? Physical and biological verifications of a novel treatment modality.
Published in:
Medical Physics, 2016, v. 43, n. 4, p. 1995, doi. 10.1118/1.4944593
By:
- Krämer, Michael;
- Scifoni, Emanuele;
- Schuy, Christoph;
- Rovituso, Marta;
- Tinganelli, Walter;
- Maier, Andreas;
- Kaderka, Robert;
- Kraft‐Weyrather, Wilma;
- Brons, Stephan;
- Tessonnier, Thomas;
- Parodi, Katia;
- Durante, Marco
Publication type:
Article

Found: 44