Works by Broekhuizen, Roel

Results: 21

Protein-bound uremic toxin clearance as biomarker of kidney tubular function in diabetic kidney disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07248-3

By:

Ahmed, Sabbir;
Sparidans, Rolf W.;
Vernooij, Robin W. M.;
Mihaila, Silvia M.;
Broekhuizen, Roel;
Goldschmeding, Roel;
Nguyen, Tri Q.;
Masereeuw, Rosalinde;
Gerritsen, Karin G. F.

Publication type:

Article

Correction to: FoxD1-driven CCN2 deletion causes axial skeletal deformities, pulmonary hypoplasia, and neonatal asphyctic death.

Published in:

2020

By:

Falke, Lucas L.;
He, Nannan;
Chuva de Sousa Lopes, Susana M.;
Broekhuizen, Roel;
Lyons, Karen;
Nguyen, Tri Q.;
Goldschmeding, Roel

Publication type:

Correction Notice

Tamoxifen for induction of Cre-recombination may confound fibrosis studies in female mice.

Published in:

2017

By:

Falke, Lucas;
Broekhuizen, Roel;
Huitema, Alwin;
Maarseveen, Erik;
Nguyen, Tri;
Goldschmeding, Roel

Publication type:

Report

Connective tissue growth factor and the cicatrization of cellular crescents in ANCA-associated glomerulonephritis.

Published in:

Nephrology Dialysis Transplantation, 2015, v. 30, n. 8, p. 1291, doi. 10.1093/ndt/gfv088

By:

Hilhorst, Marc;
Kok, Helena M.;
Broekhuizen, Roel;
van Paassen, Pieter;
van Breda Vriesman, Peter;
Goldschmeding, Roel;
Nguyen, Tri Q.;
Cohen Tervaert, Jan Willem

Publication type:

Article

Extracellular Granzyme K Modulates Angiogenesis by Regulating Soluble VEGFR1 Release From Endothelial Cells.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.681967

By:

Li, Shuang;
van Dijk, Christian G. M.;
Meeldijk, Jan;
Kok, Helena M.;
Blommestein, Isabelle;
Verbakel, Annick L. F.;
Kotte, Marit;
Broekhuizen, Roel;
Laclé, Miangela M.;
Goldschmeding, Roel;
Cheng, Caroline;
Bovenschen, Niels

Publication type:

Article

CCN2/CTGF expression does not correlate with fibrosis in myeloproliferative neoplasms, consistent with noncanonical TGF-β signaling driving myelofibrosis.

Published in:

Virchows Archiv: European Journal of Pathology, 2024, v. 484, n. 5, p. 837, doi. 10.1007/s00428-024-03799-4

By:

Leguit, Roos J.;
Broekhuizen, Roel;
de Witte, Moniek;
Raymakers, Reinier A. P.;
Goldschmeding, Roel

Publication type:

Article

Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151465

By:

Vermeulen, Jeroen F.;
van Hecke, Wim;
Spliet, Wim G. M.;
Villacorta Hidalgo, José;
Fisch, Paul;
Broekhuizen, Roel;
Bovenschen, Niels

Publication type:

Article

Proteomic profiling of the spinal cord in ALS: decreased ATP5D levels suggest synaptic dysfunction in ALS pathogenesis.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2017, v. 18, n. 3/4, p. 210, doi. 10.1080/21678421.2016.1245757

By:

Engelen-Lee, Jooyeon;
Blokhuis, Anna M.;
Spliet, Wim G. M.;
Pasterkamp, R. Jeroen;
Aronica, Eleonora;
Demmers, Jeroen A. A.;
Broekhuizen, Roel;
Nardo, Giovanni;
Bovenschen, Niels;
Van Den Berg, Leonard H.

Publication type:

Article

Prognostic relevance of tumor-infiltrating lymphocytes and immune checkpoints in pediatric medulloblastoma.

Published in:

OncoImmunology, 2018, v. 7, n. 3, p. 1, doi. 10.1080/2162402X.2017.1398877

By:

Vermeulen, Jeroen F.;
Hecke, Wim Van;
Adriaansen, Elisabeth J. M.;
Jansen, Mieke K.;
Boum, Rianne G.;
Hidalgo, José Villacorta;
Fisch, Paul;
Broekhuizen, Roel;
Spliet, Wim G. M.;
Kool, Marcel;
Bovenschen, Niels

Publication type:

Article

Plasma CTGF is independently related to an increased risk of cardiovascular events and mortality in patients with atherosclerotic disease: the SMART study.

Published in:

Growth Factors, 2016, v. 34, n. 3/4, p. 149, doi. 10.1080/08977194.2016.1210142

By:

Gerritsen, Karin G.;
Falke, Lucas L.;
van Vuuren, Stefan H.;
Leeuwis, Jan W.;
Broekhuizen, Roel;
Nguyen, Tri Q.;
de Borst, Gert Jan;
Nathoe, Hendrik M.;
Verhaar, Marianne C.;
Kok, Robbert J.;
Goldschmeding, Roel;
Visseren, Frank L.

Publication type:

Article

An improved, sensitive, non-radioactive in situ hybridization method for the detection of cytokine mRNAs.

Published in:

APMIS, 1995, v. 103, n. 1-6, p. 345, doi. 10.1111/j.1699-0463.1995.tb01118.x

By:

Klein, SIGRID C.;
Wichen, DICK F.;
Golverdingen, JOKE G.;
Jacobse, KAREN C.;
Broekhuizen, ROEL;
Weger, ROEL A.

Publication type:

Article

Downregulation of SERPINB13 expression in head and neck squamous cell carcinomas associates with poor clinical outcome.

Published in:

International Journal of Cancer, 2009, v. 125, n. 7, p. 1542, doi. 10.1002/ijc.24507

By:

de Koning, Pieter J.A.;
Bovenschen, Niels;
Leusink, Frank K.J.;
Broekhuizen, Roel;
Quadir, Razi;
van Gemert, Jan T.M.;
Hordijk, Gerrit J.;
Chang, Wun-Shaing W.;
van der Tweel, Ingeborg;
Tilanus, Marcel G.J.;
Kummer, J. Alain

Publication type:

Article

CCN2 Aggravates the Immediate Oxidative Stress–DNA Damage Response following Renal Ischemia–Reperfusion Injury.

Published in:

Antioxidants, 2021, v. 10, n. 12, p. 2020, doi. 10.3390/antiox10122020

By:

Valentijn, Floris A.;
Knoppert, Sebastiaan N.;
Pissas, Georgios;
Rodrigues-Diez, Raúl R.;
Marquez-Exposito, Laura;
Broekhuizen, Roel;
Mokry, Michal;
Kester, Lennart A.;
Falke, Lucas L.;
Goldschmeding, Roel;
Ruiz-Ortega, Marta;
Eleftheriadis, Theodoros;
Nguyen, Tri Q.

Publication type:

Article

Connective Tissue Growth Factor Is Overexpressed in Explant Lung Tissue and Broncho-Alveolar Lavage in Transplant-Related Pulmonary Fibrosis.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.661761

By:

Vanstapel, Arno;
Goldschmeding, Roel;
Broekhuizen, Roel;
Nguyen, Tri;
Sacreas, Annelore;
Kaes, Janne;
Heigl, Tobias;
Verleden, Stijn E.;
De Zutter, Alexandra;
Verleden, Geert;
Weynand, Birgit;
Verbeken, Erik;
Ceulemans, Laurens J.;
Van Raemdonck, Dirk E.;
Neyrinck, Arne P.;
Schoemans, Helene M.;
Vanaudenaerde, Bart M.;
Vos, Robin

Publication type:

Article

Compensatory Growth of Congenital Solitary Kidneys in Pigs Reflects Increased Nephron Numbers Rather Than Hypertrophy.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049735

By:

van Vuuren, Stefan H.;
Sol, Chalana M.;
Broekhuizen, Roel;
Lilien, Marc R.;
Oosterveld, Michiel J. S.;
Nguyen, Tri Q.;
Goldschmeding, Roel;
de Jong, Tom P. V. M.

Publication type:

Article

Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0022645

By:

de Koning, Pieter J. A.;
Kummer, J. Alain;
de Poot, Stefanie A. H.;
Quadir, Razi;
Broekhuizen, Roel;
McGettrick, Anne F.;
Higgins, Wayne J.;
Devreese, Bart;
Worrall, D. Margaret;
Bovenschen, Niels

Publication type:

Article

CCN2 Activates Cellular Senescence Leading to Kidney Fibrosis in Folic Acid-Induced Experimental Nephropathy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4401, doi. 10.3390/ijms26094401

By:

Tejedor-Santamaria, Lucia;
Marquez-Exposito, Laura;
Villacampa, Alicia;
Marchant, Vanessa;
Battaglia-Vieni, Antonio;
Rayego-Mateos, Sandra;
Rodrigues-Diez, Raul R.;
Santos, Fatima Milhano;
Valentijn, Floris A.;
Knoppert, Sebastian N.;
Broekhuizen, Roel;
Ruiz-Torres, María Piedad;
Goldschmeding, Roel;
Ortiz, Alberto;
Peiró, Concepción;
Nguyen, Tri Q.;
Ramos, Adrián M.;
Ruiz-Ortega, Marta

Publication type:

Article

Biological responses of human solid tumor cells to X-ray irradiation within a 1.5-Tesla magnetic field generated by a magnetic resonance imaging-linear accelerator.

Published in:

Bioelectromagnetics, 2016, v. 37, n. 7, p. 471, doi. 10.1002/bem.21991

By:

Wang, Li;
Hoogcarspel, Stan Jelle;
Wen, Zhifei;
van Vulpen, Marco;
Molkentine, David P.;
Kok, Jan;
Lin, Steven H.;
Broekhuizen, Roel;
Ang, Kie‐Kian;
Bovenschen, Niels;
Raaymakers, Bas W.;
Frank, Steven J.

Publication type:

Article

No evidence for human cytomegalovirus infection in pediatric medulloblastomas.

Published in:

Neuro-Oncology, 2016, v. 18, n. 10, p. 1461, doi. 10.1093/neuonc/now151

By:

Vermeulen, Jeroen F.;
van Hecke, Wim;
Jansen, Mieke K.;
Spliet, Wim G. M.;
Broekhuizen, Roel;
Bovenschen, Niels

Publication type:

Article

The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells.

Published in:

European Journal of Immunology, 2005, v. 35, n. 4, p. 1175, doi. 10.1002/eji.200425949

By:

Bladergroen, Bellinda A.;
Strik, Merel C. M.;
Wolbink, Angela M.;
Wouters, Dorine;
Broekhuizen, Roel;
Kummer, J. Alain;
Hack, C. Erik

Publication type:

Article

Cellular senescence in kidney biopsies is associated with tubular dysfunction and predicts CKD progression in childhood cancer patients with karyomegalic interstitial nephropathy.

Published in:

Journal of Pathology, 2023, v. 261, n. 4, p. 455, doi. 10.1002/path.6202

By:

Knoppert, Sebastiaan N;
Keijzer‐Veen, Mandy G;
Valentijn, Floris A;
van den Heuvel‐Eibrink, Marry M;
Lilien, Marc R;
van den Berg, Gerrit;
Haveman, Lianne M;
Stokman, Marijn F;
Janssens, Geert O;
van Kempen, Sven;
Broekhuizen, Roel;
Goldschmeding, Roel;
Nguyen, Tri Q

Publication type:

Article