Works matching AU Brinkmann, Ulrich

Results: 61

Digoxin pharmacokinetics and MDR1 genetic polymorphisms.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 58, n. 12, p. 809, doi. 10.1007/s00228-003-0567-5

By:

Verstuyft, Céline;
Schwab, Mathias;
Schaeffeler, Elke;
Kerb, Reinhold;
Brinkmann, Ulrich;
Jaillon, Patrice;
Funck-Brentano, Christian;
Becquemont, Laurent

Publication type:

Article

Cloning and expression of the recombinant FAb fragment of monoclonal antibody K1 that reacts with mesothelin present on mesotheliomas and ovarian cancers.

Published in:

International Journal of Cancer, 1997, v. 71, n. 4, p. 638, doi. 10.1002/(SICI)1097-0215(19970516)71:4<638::AID-IJC21>3.0.CO;2-6

By:

Brinkmann, Ulrich;
Webber, Keith;
Di Carlo, Angelina;
Beers, Richard;
Chowdhury, Partha;
Chang, Kai;
Chaudhary, Vijay;
Gallo, Maria;
Pastan, Ira

Publication type:

Article

Cytotoxic and antitumor activity of a recombinant immunotoxin composed of disulfide-stabilized anti-TAC Fv fragment and truncated pseudomonas exotoxin.

Published in:

International Journal of Cancer, 1994, v. 58, n. 1, p. 142, doi. 10.1002/ijc.2910580123

By:

Reiter, Yoram;
Kreitman, Robert J.;
Brinkmann, Ulrich;
Pastan, Ira

Publication type:

Article

CORONA-KRISE IM BETRIEB.

Published in:

Wirtschafts- und Sozialwissenschaftliches Institut Mitteilungen, 2022, v. 75, n. 3, p. 257, doi. 10.5771/0342-300X-2022-3-257

By:

Brinkmann, Ulrich

Publication type:

Article

Corona-Krise - Stresstest für die Mitbestimmung.

Published in:

Wirtschafts- und Sozialwissenschaftliches Institut Mitteilungen, 2021, v. 74, n. 4, p. 296, doi. 10.5771/0342-300X-2021-4-296

By:

BEHRUZI, DANIEL;
BRINKMANN, ULRICH;
PAULITZ, TANJA

Publication type:

Article

Solidarität und Skepsis: Flucht, Migration und soziale Frage aus der Sicht gewerkschaftlich Engagierter.

Published in:

Wirtschafts- und Sozialwissenschaftliches Institut Mitteilungen, 2019, v. 72, n. 3, p. 202, doi. 10.5771/0342-300X-2019-3-202

By:

BRINKMANN, ULRICH;
HASSAN-BEIK, MAREN;
ZAPPINO, LUKAS

Publication type:

Article

Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast.

Published in:

PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0205870

By:

Hawer, Harmen;
Ütkür, Koray;
Arend, Meike;
Mayer, Klaus;
Adrian, Lorenz;
Brinkmann, Ulrich;
Schaffrath, Raffael

Publication type:

Article

Polymorphisms of the apoptosis-associated gene DP1L1 (deleted in polyposis 1-like 1) in colon cancer and inflammatory bowel disease.

Published in:

Journal of Cancer Research & Clinical Oncology, 2010, v. 136, n. 6, p. 795, doi. 10.1007/s00432-009-0719-9

By:

Wellmann, Axel;
Fogt, Franz;
Hollerbach, Stephan;
Hahne, Jens;
Koenig-Hoffmann, Kerstin;
Smeets, Daniela;
Brinkmann, Ulrich

Publication type:

Article

Common denominator procedure: a novel approach to gene-expression data mining for identification of phenotype-specific genes.

Published in:

Bioinformatics, 2005, v. 21, n. 11, p. 2766, doi. 10.1093/bioinformatics/bti416

By:

René Korn;
Sascha Röhrig;
Steffen Schulze-Kremer;
Ulrich Brinkmann

Publication type:

Article

Zirconium-89 labeled antibodies: a new tool for molecular imaging in cancer patients.

Published in:

2014

By:

van de Watering, Floor C J;
Rijpkema, Mark;
Perk, Lars;
Brinkmann, Ulrich;
Oyen, Wim J G;
Boerman, Otto C

Publication type:

Journal Article

Zirconium-89 Labeled Antibodies: A New Tool for Molecular Imaging in Cancer Patients.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/203601

By:

van de Watering, Floor C. J.;
Rijpkema, Mark;
Perk, Lars;
Brinkmann, Ulrich;
Oyen, Wim J. G.;
Boerman, Otto C.

Publication type:

Article

Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31712-7

By:

Zhang, Hongliang;
Quintana, Julia;
Ütkür, Koray;
Adrian, Lorenz;
Hawer, Harmen;
Mayer, Klaus;
Gong, Xiaodi;
Castanedo, Leonardo;
Schulten, Anna;
Janina, Nadežda;
Peters, Marcus;
Wirtz, Markus;
Brinkmann, Ulrich;
Schaffrath, Raffael;
Krämer, Ute

Publication type:

Article

Influence of DPH1 and DPH5 Protein Variants on the Synthesis of Diphthamide, the Target of ADP-Ribosylating Toxins.

Published in:

Toxins, 2017, v. 9, n. 3, p. 78, doi. 10.3390/toxins9030078

By:

Mayer, Klaus;
Schröder, Anna;
Schnitger, Jerome;
Stahl, Sebastian;
Brinkmann, Ulrich

Publication type:

Article

MicroRNAs Involved in Metastasis of Hepatocellular Carcinoma: Target Candidates, Functionality and Efficacy in Animal Models and Prognostic Relevance.

Published in:

Cancer Genomics & Proteomics (1109-6535), 2020, v. 17, n. 1, p. 1, doi. 10.21873/cgp.20163

By:

WEIDLE, ULRICH H.;
SCHMID, DANIELA;
BIRZELE, FABIAN;
BRINKMANN, ULRICH

Publication type:

Article

The Functional Role of Prostate Cancer Metastasis-related Micro-RNAs.

Published in:

Cancer Genomics & Proteomics (1109-6535), 2019, v. 16, n. 1, p. 1, doi. 10.21873/cgp.20108

By:

WEIDLE, ULRICH H.;
EPP, ALEXANDRA;
BIRZELE, FABIAN;
BRINKMANN, ULRICH

Publication type:

Article

A Novel Angiopoietin-2 Selective Fully Human Antibody with Potent Anti-Tumoral and Anti-Angiogenic Efficacy and Superior Side Effect Profile Compared to Pan-Angiopoietin-1/-2 Inhibitors.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0054923

By:

Thomas, Markus;
Kienast, Yvonne;
Scheuer, Werner;
Bähner, Monika;
Kaluza, Klaus;
Gassner, Christian;
Herting, Frank;
Brinkmann, Ulrich;
Seeber, Stefan;
Kavlie, Anita;
Welschof, Martin;
Ries, Stefan;
Weidner, K. Michael;
Regula, Jörg T.;
Klein, Christian

Publication type:

Article

Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.

Published in:

FASEB Journal, 2015, v. 29, n. 5, p. 1763, doi. 10.1096/fj.14-263665

By:

Dengl, Stefan;
Hoffmann, Eike;
Grote, Michael;
Wagner, Cornelia;
Mundigl, Olaf;
Georges, Guy;
Thorey, Irmgard;
Stubenrauch, Kay-Gunnar;
Bujotzek, Alexander;
Josel, Hans-Peter;
Dziadek, Sebastian;
Benz, Joerg;
Brinkmann, Ulrich

Publication type:

Article

Back-to-Germline (B2G) Procedure for Antibody Devolution.

Published in:

Antibodies (2073-4468), 2019, v. 8, n. 3, p. 45, doi. 10.3390/antib8030045

By:

Schrade, Anja;
Bujotzek, Alexander;
Spick, Christian;
Wagner, Martina;
Goerl, Johannes;
Wezler, Xenia;
Georges, Guy;
Kontermann, Roland E.;
Brinkmann, Ulrich

Publication type:

Article

Targeted chain-exchange-mediated reconstitution of a split type-I cytokine for conditional immunotherapy.

Published in:

2023

By:

Vasic, Vedran;
Buldun, Can;
Ritz, Manfred;
Dickopf, Steffen;
Georges, Guy J.;
Spick, Christian;
Peuker, Alessa;
Meier, Thomas;
Mayer, Klaus;
Brinkmann, Ulrich

Publication type:

Report

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity.

Published in:

2019

By:

Sustmann, Claudio;
Dickopf, Steffen;
Regula, Jörg T.;
Kettenberger, Hubert;
Mølhøj, Michael;
Gassner, Christian;
Weininger, Diana;
Fenn, Sebastian;
Manigold, Tobias;
Kling, Lothar;
Künkele, Klaus-Peter;
Schwaiger, Manfred;
Bossenmaier, Birgit;
Griese, Julia J.;
Hopfner, Karl-Peter;
Graff-Meyer, Alexandra;
Stahlberg, Henning;
Ringler, Philippe;
Lauer, Matthias E.;
Brinkmann, Ulrich

Publication type:

Report

The making of bispecific antibodies.

Published in:

mAbs (1942-0862), 2017, v. 9, n. 2, p. 182, doi. 10.1080/19420862.2016.1268307

By:

Brinkmann, Ulrich;
Kontermann, Roland E.

Publication type:

Article

Anti-tumoral, anti-angiogenic and anti-metastatic efficacy of a tetravalent bispecific antibody (TAvi6) targeting VEGF-A and angiopoietin-2.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 3, p. 562, doi. 10.1080/19420862.2016.1147640

By:

Scheuer, Werner;
Thomas, Markus;
Hanke, Petra;
Sam, Johannes;
Osl, Franz;
Weininger, Diana;
Baehner, Monika;
Seeber, Stefan;
Kettenberger, Hubert;
Schanzer, Jürgen;
Brinkmann, Ulrich;
Weidner, K. Michael;
Regula, Jörg;
Klein, Christian

Publication type:

Article

Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies.

Published in:

mAbs (1942-0862), 2012, v. 4, n. 6, p. 653, doi. 10.4161/mabs.21379

By:

Klein, Christian;
Sustmann, Claudio;
Thomas, Markus;
Stubenrauch, Kay;
Croasdale, Rebecca;
Schanzer, Jürgen;
Brinkmann, Ulrich;
Kettenberger, Hubert;
Regula, Jörg T.;
Schaefer, Wolfgang

Publication type:

Article

Effects of Ultrasonic Dispersion Energy on the Preparation of Amorphous SiO2 Nanomaterials for In Vitro Toxicity Testing.

Published in:

Nanomaterials (2079-4991), 2019, v. 9, n. 1, p. 11, doi. 10.3390/nano9010011

By:

Wiemann, Martin;
Vennemann, Antje;
Stintz, Michael;
Retamal Marín, Rodrigo R.;
Babick, Frank;
Lindner, Gottlieb-Georg;
Schuster, Tobias B.;
Brinkmann, Ulrich;
Krueger, Nils

Publication type:

Article

Handlungsmacht gegen rechts.

Published in:

Blätter für Deutsche und Internationale Politik, 2024, v. 69, n. 9, p. 125

By:

Brinkmann, Ulrich

Publication type:

Article

Internalisation of Markets and Internal Entrepreneurship: Competition or Co-operation?

Published in:

International Journal of Action Research, 2011, v. 7, n. 2, p. 196, doi. 10.1688/1861-9916&lowbar;IJAR&lowbar;2011&lowbar;02&lowbar;Brinkmann

By:

Brinkmann, Ulrich

Publication type:

Article

Functional Integrity of Radical SAM Enzyme Dph1•Dph2 Requires Non-Canonical Cofactor Motifs with Tandem Cysteines.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 4, p. 470, doi. 10.3390/biom14040470

By:

Ütkür, Koray;
Mayer, Klaus;
Liu, Shihui;
Brinkmann, Ulrich;
Schaffrath, Raffael

Publication type:

Article

DPH1 Gene Mutations Identify a Candidate SAM Pocket in Radical Enzyme Dph1•Dph2 for Diphthamide Synthesis on EF2.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 11, p. 1655, doi. 10.3390/biom13111655

By:

Ütkür, Koray;
Schmidt, Sarina;
Mayer, Klaus;
Klassen, Roland;
Brinkmann, Ulrich;
Schaffrath, Raffael

Publication type:

Article

Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18477-7

By:

Dengl, Stefan;
Mayer, Klaus;
Bormann, Felix;
Duerr, Harald;
Hoffmann, Eike;
Nussbaum, Bianca;
Tischler, Michael;
Wagner, Martina;
Kuglstatter, Andreas;
Leibrock, Lea;
Buldun, Can;
Georges, Guy;
Brinkmann, Ulrich

Publication type:

Article

How to Manage Individualized Drug Therapy: Application of Pharmacogenetic Knowledge of Drug Metabolism and Transport.

Published in:

Clinical Chemistry & Laboratory Medicine, 2000, v. 38, n. 9, p. 869

By:

Meisel, Christian;
Roots, Ivar;
Cascorbi, Ingolf;
Brinkmann, Ulrich;
Brockmöller, Jürgen

Publication type:

Article

Functional characterization of the 5′-regulatory region of human CYP2C19.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 2, p. P60, doi. 10.1016/S0009-9236(03)90579-0

By:

Arefayene, Million;
Zhao, Xiaojiong;
Tanus-Santos, Jose E.;
Brinkmann, Ulrich;
Brehm, Ilka;
Nguyen, Anne;
Flockhart, David A.;
Skaar, Todd

Publication type:

Article

Dipyridamole enhances digoxin bioavailability via P-glycoprotein inhibition*.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 1, p. 51, doi. 10.1067/mcp.2003.8

By:

Verstuyft, Céline;
Strabach, Soraya;
El Morabet, Hakima;
Kerb, Reinhold;
Brinkmann, Ulrich;
Dubert, Liliane;
Jaillon, Patrice;
Funck-Brentano, Christian;
Trugnan, Germain;
Becquemont, Laurent

Publication type:

Article

Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene*.

Published in:

Clinical Pharmacology & Therapeutics, 2002, v. 72, n. 5, p. 584, doi. 10.1067/mcp.2002.129196

By:

Johne, Andreas;
Köpke, Karla;
Gerloff, Thomas;
Mai, Ingrid;
Rietbrock, Stephan;
Meisel, Christian;
Hoffmeyer, Sven;
Kerb, Reinhold;
Fromm, Martin F.;
Brinkmann, Ulrich;
Eichelbaum, Michel;
Brockmöller, Jürgen;
Cascorbi, Ingolf;
Roots, Ivar

Publication type:

Article

Effect of grapefruit juice on digoxin pharmacokinetics in humans*.

Published in:

Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 4, p. 311, doi. 10.1016/S0009-9236(01)17221-8

By:

Becquemont, Laurent;
Verstuyft, Céline;
Kerb, Reinhold;
Brinkmann, Ulrich;
Lebot, Martine;
Jaillon, Patrice;
Funck-Brentano, Christian

Publication type:

Article

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects*.

Published in:

Clinical Pharmacology & Therapeutics, 2001, v. 69, n. 3, p. 169, doi. 10.1067/mcp.2001.114164

By:

Cascorbi, Ingolf;
Gerloff, Thomas;
Johne, Andreas;
Meisel, Christian;
Hoffmeyer, Sven;
Schwab, Matthias;
Schaeffeler, Elke;
Eichelbaum, Michel;
Brinkmann, Ulrich;
Roots, Ivar

Publication type:

Article

Attenuating the growth of tumors by intratumoral administration of DNA encoding Pseudomonas exotoxin via cationic liposomes.

Published in:

Cancer Gene Therapy, 2000, v. 7, n. 1, p. 91, doi. 10.1038/sj.cgt.7700115

By:

Yerushalmi, Noga;
Brinkmann, Ulrich;
Brinkmann, Elisabeth;
Pai, Lee;
Pastan, Ira

Publication type:

Article

Engineered hapten-binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload delivery.

Published in:

Immunological Reviews, 2016, v. 270, n. 1, p. 165, doi. 10.1111/imr.12386

By:

Dengl, Stefan;
Sustmann, Claudio;
Brinkmann, Ulrich

Publication type:

Article

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

Published in:

British Journal of Clinical Pharmacology, 2002, v. 53, n. 5, p. 526, doi. 10.1046/j.1365-2125.2002.01591.x

By:

Drescher, Siegfried;
Schaeffeler, Elke;
Hitzl, Monika;
Hofmann, Ute;
Schwab, Matthias;
Brinkmann, Ulrich;
Eichelbaum, Michel;
Fromm, Martin F

Publication type:

Article

Generation of binder-format-payload conjugate-matrices by antibody chain-exchange.

Published in:

Nature Communications, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41467-024-53730-3

By:

Vasic, Vedran;
Dickopf, Steffen;
Spranger, Nadine;
Rosenberger, Rose-Sophie;
Fischer, Michaela;
Mayer, Klaus;
Larraillet, Vincent;
Bates, Jack A.;
Maier, Verena;
Sela, Tatjana;
Nussbaum, Bianca;
Duerr, Harald;
Dengl, Stefan;
Brinkmann, Ulrich

Publication type:

Article

Induction of heat shock protein HSPA6 (HSP70B′) upon HSP90 inhibition in cancer cell lines.

Published in:

FEBS Letters, 2015, v. 589, n. 13, p. 1450, doi. 10.1016/j.febslet.2015.04.053

By:

Kuballa, Petric;
Baumann, Anna-Lena;
Mayer, Klaus;
Bär, Ute;
Burtscher, Helmut;
Brinkmann, Ulrich

Publication type:

Article

Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 10, p. e55, doi. 10.1093/nar/gkz137

By:

Killian, Tobias;
Buntz, Annette;
Herlet, Teresa;
Seul, Heike;
Mundigl, Olaf;
Längst, Gernot;
Brinkmann, Ulrich

Publication type:

Article

Quantitative fluorescence imaging determines the absolute number of locked nucleic acid oligonucleotides needed for suppression of target gene expression.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 2, p. 953, doi. 10.1093/nar/gky1158

By:

Buntz, Annette;
Killian, Tobias;
Schmid, Daniela;
Seul, Heike;
Brinkmann, Ulrich;
Ravn, Jacob;
Lindholm, Marie;
Knoetgen, Hendrik;
Haucke, Volker;
Mundigl, Olaf

Publication type:

Article

Bispecific antibody derivatives with restricted binding functionalities that are activated by proteolytic processing.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 571, doi. 10.1093/protein/gzs064

By:

Metz, Silke;
Panke, Christian;
Haas, Alexander K.;
Schanzer, Jürgen;
Lau, Wilma;
Croasdale, Rebecca;
Hoffmann, Eike;
Schneider, Britta;
Auer, Johannes;
Gassner, Christian;
Bossenmaier, Birgit;
Umana, Pablo;
Sustmann, Claudio;
Brinkmann, Ulrich

Publication type:

Article

Recombinant Toxins: New Therapeutic Agents for Cancer.

Published in:

Annals of the New York Academy of Sciences, 1995, v. 758, n. 1, p. 345, doi. 10.1111/j.1749-6632.1995.tb24840.x

By:

PASTAN, IRA H.;
PAI, LEE H.;
BRINKMANN, ULRICH;
FITZGERALD, DAVID J.

Publication type:

Article

TriFabs--Trivalent IgG-Shaped Bispecific Antibody Derivatives: Design, Generation, Characterization and Application for Targeted Payload Delivery.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 11, p. 27497, doi. 10.3390/ijms161126037

By:

Mayer, Klaus;
Baumann, Anna-Lena;
Grote, Michael;
Seeber, Stefan;
Kettenberger, Hubert;
Breuer, Sebastian;
Killian, Tobias;
Schäfer, Wolfgang;
Brinkmann, Ulrich

Publication type:

Article

Liefern am Limit Wie die Plattformökonomie die Arbeitsbeziehungen verändert.

Published in:

Industrielle Beziehungen, 2020, v. 27, n. 2, p. 120, doi. 10.3224/indbez.v27i2.02

By:

Heiland, Heiner;
Brinkmann, Ulrich

Publication type:

Article

Prekäre Demokratie? Zu den Auswirkungen atypischer Beschäftigung auf die betriebliche Mitbestimmung.

Published in:

Industrielle Beziehungen, 2014, v. 21, n. 1, p. 78, doi. 10.1688/IndB-2014-01-Brinkmann

By:

Brinkmann, Ulrich;
Nachtwey, Oliver

Publication type:

Article

Loss of the TOL meta-cleavage pathway functions of Pseudomonas putida strain PaW1 (pWW0) during growth on toluene.

Published in:

Journal of Basic Microbiology, 1994, v. 34, n. 5, p. 303, doi. 10.1002/jobm.3620340503

By:

Brinkmann, Ulrich;
Ramos, Juan L.;
Reineke, Walter

Publication type:

Article

High throughput functional genomics: Identification of novel genes with tumor suppressor phenotypes.

Published in:

International Journal of Cancer, 2005, v. 113, n. 3, p. 434, doi. 10.1002/ijc.20601

By:

Koenig-Hoffmann, Kerstin;
Bonin-Debs, Angelika L.;
Boche, Irene;
Gawin, Beate;
Gnirke, Andrea;
Hergersberg, Christoph;
Madeo, Frank;
Kazinski, Michael;
Klein, Matthias;
Korherr, Christian;
Link, Dieter;
Röhrig, Sascha;
Schäfer, Rolf;
Brinkmann, Ulrich

Publication type:

Article

Drawing out the Reader: Tourism, Literature, Individuality.

Published in:

Postmodern Studies, 2011, v. 45, p. 229

By:

Brinkmann, Ulrich

Publication type:

Article