Works by Brindle, Kevin M.

Results: 106

The role of branched-chain aminotransferase 1 in driving glioblastoma cell proliferation and invasion varies with tumor subtype.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad120

By:

Fala, Maria;
Ros, Susana;
Sawle, Ashley;
Rao, Jyotsna U;
Tsyben, Anastasia;
Tronci, Laura;
Frezza, Christian;
Mair, Richard;
Brindle, Kevin M

Publication type:

Article

18F-C2Am: a targeted imaging agent for detecting tumor cell death in vivo using positron emission tomography.

Published in:

EJNMMI Research, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13550-020-00738-7

By:

Bulat, Flaviu;
Hesse, Friederike;
Hu, De-En;
Ros, Susana;
Willminton-Holmes, Connor;
Xie, Bangwen;
Attili, Bala;
Soloviev, Dmitry;
Aigbirhio, Franklin;
Leeper, Finian. J.;
Brindle, Kevin M.;
Neves, André A.

Publication type:

Article

Preclinical PET Imaging of Tumor Cell Death following Therapy Using Gallium-68-Labeled C2Am.

Published in:

Cancers, 2023, v. 15, n. 5, p. 1564, doi. 10.3390/cancers15051564

By:

Bulat, Flaviu;
Hesse, Friederike;
Attili, Bala;
Solanki, Chandra;
Mendichovszky, Iosif A.;
Aigbirhio, Franklin;
Leeper, Finian J.;
Brindle, Kevin M.;
Neves, André A.

Publication type:

Article

Labile Photo‐Induced Free Radical in α‐Ketoglutaric Acid: a Universal Endogenous Polarizing Agent for In Vivo Hyperpolarized 13C Magnetic Resonance.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 2, p. 1, doi. 10.1002/anie.202112982

By:

Gaunt, Adam P.;
Lewis, Jennifer S.;
Hesse, Friederike;
Cheng, Tian;
Marco‐Rius, Irene;
Brindle, Kevin M.;
Comment, Arnaud

Publication type:

Article

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway.

Published in:

Biological Reviews, 2015, v. 90, n. 3, p. 927, doi. 10.1111/brv.12140

By:

Stincone, Anna;
Prigione, Alessandro;
Cramer, Thorsten;
Wamelink, Mirjam M. C.;
Campbell, Kate;
Cheung, Eric;
Olin‐Sandoval, Viridiana;
Grüning, Nana‐Maria;
Krüger, Antje;
Tauqeer Alam, Mohammad;
Keller, Markus A.;
Breitenbach, Michael;
Brindle, Kevin M.;
Rabinowitz, Joshua D.;
Ralser, Markus

Publication type:

Article

Analysis of metabolic control In Vivo using molecular genetics.

Published in:

Cell Biochemistry & Function, 1996, v. 14, n. 4, p. 269, doi. 10.1002/cbf.701

By:

Brindle, Kevin M.

Publication type:

Article

Glyoxalase activity in human erythrocytes and mouse lymphoma, liver and brain probed with hyperpolarized 13C-methylglyoxal.

Published in:

Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0241-1

By:

Shishmarev, Dmitry;
Kuchel, Philip W.;
Pagès, Guilhem;
Wright, Alan J.;
Hesketh, Richard L.;
Kreis, Felix;
Brindle, Kevin M.

Publication type:

Article

Magnetic resonance fingerprinting of the pancreas at 1.5 T and 3.0 T.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-74462-6

By:

Serrao, Eva M.;
Kessler, Dimitri A.;
Carmo, Bruno;
Beer, Lucian;
Brindle, Kevin M.;
Buonincontri, Guido;
Gallagher, Ferdia A.;
Gilbert, Fiona J.;
Godfrey, Edmund;
Graves, Martin J.;
McLean, Mary A.;
Sala, Evis;
Schulte, Rolf F.;
Kaggie, Joshua D.

Publication type:

Article

Detection of cell‐free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 12, p. N.PAG, doi. 10.15252/emmm.201809323

By:

Mouliere, Florent;
Mair, Richard;
Chandrananda, Dineika;
Marass, Francesco;
Smith, Christopher G;
Su, Jing;
Morris, James;
Watts, Colin;
Brindle, Kevin M;
Rosenfeld, Nitzan

Publication type:

Article

Versatile and enhanced tumour modelling in mice via somatic cell transduction.

Published in:

Journal of Pathology, 2014, v. 232, n. 4, p. 449, doi. 10.1002/path.4313

By:

Rodriguez, Esther;
Mannion, Liz;
D'Santos, Paula;
Griffiths, Meryl;
Arends, Mark J;
Brindle, Kevin M;
Lyons, Scott K

Publication type:

Article

Superparamagnetic Iron Oxide-Labeled Schwann Cells and Olfactory Ensheathing Cells Can Be Traced In Vivo by Magnetic Resonance Imaging and Retain Functional Properties after Transplantation into the CNS.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 44, p. 9799, doi. 10.1523/JNEUROSCI.3126-04.2004

By:

Dunning, Mark D.;
Lakatos, Andras;
Loizou, Louiza;
Kettunen, Mikko;
Ffrench-Constant, Charles;
Brindle, Kevin M.;
Franklin, Robin J. M.

Publication type:

Article

Imaging sialylated tumor cell glycans in vivo.

Published in:

FASEB Journal, 2011, v. 25, n. 8, p. 2528, doi. 10.1096/fj.10-178590

By:

Neves, André A.;
Stöckmann, Henning;
Harmston, Rebecca R.;
Pryor, Helen J.;
Alam, Israt S.;
Ireland-Zecchini, Heather;
Lewis, David Y.;
Lyons, Scott K.;
Leeper, Finian J.;
Brindle, Kevin M.

Publication type:

Article

Metabolic Glycan Imaging by Isonitrile-Tetrazine Click Chemistry.

Published in:

ChemBioChem, 2013, v. 14, n. 9, p. 1063, doi. 10.1002/cbic.201300130

By:

Stairs, Shaun;
Neves, André A.;
Stöckmann, Henning;
Wainman, Yelena A.;
Ireland‐Zecchini, Heather;
Brindle, Kevin M.;
Leeper, Finian J.

Publication type:

Article

Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1-.

Published in:

Magnetic Resonance in Medicine, 2011, v. 65, n. 2, p. 557, doi. 10.1002/mrm.22698

By:

Day, Sam E.;
Kettunen, Mikko I.;
Cherukuri, Murali Krishna;
Mitchell, James B.;
Lizak, Martin J.;
Morris, H. Douglas;
Matsumoto, Shingo;
Koretsky, Alan P.;
Brindle, Kevin M.

Publication type:

Article

Magnetization transfer measurements of exchange between hyperpolarized [1-13C]pyruvate and [1-13C]lactate in a murine lymphoma.

Published in:

Magnetic Resonance in Medicine, 2010, v. 63, n. 4, p. 872, doi. 10.1002/mrm.22276

By:

Kettunen, Mikko I.;
Hu, De-en;
Witney, Timothy H.;
McLaughlin, Rebekah;
Gallagher, Ferdia A.;
Bohndiek, Sarah E.;
Day, Sam E.;
Brindle, Kevin M.

Publication type:

Article

Characterization of image heterogeneity using 2D Minkowski functionals increases the sensitivity of detection of a targeted MRI contrast agent.

Published in:

Magnetic Resonance in Medicine, 2009, v. 61, n. 5, p. 1218, doi. 10.1002/mrm.21946

By:

Canuto, Holly C.;
McLachlan, Charles;
Kettunen, Mikko I.;
Velic, Marko;
Krishnan, Anant S.;
Neves, Andre' A;
de Backer, Maaike;
Hu, D-E.;
Hobson, Michael P.;
Brindle, Kevin M.

Publication type:

Article

13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C-labeled glutamine.

Published in:

Magnetic Resonance in Medicine, 2008, v. 60, n. 2, p. 253, doi. 10.1002/mrm.21650

By:

Gallagher, Ferdia A.;
Kettunen, Mikko I.;
Day, Sam E.;
Lerche, Mathilde;
Brindle, Kevin M.

Publication type:

Article

Monitoring T-lymphocyte trafficking in tumors undergoing immune rejection.

Published in:

Magnetic Resonance in Medicine, 2005, v. 54, n. 6, p. 1473, doi. 10.1002/mrm.20717

By:

Hu, De-En;
Kettunen, Mikko I.;
Brindle, Kevin M.

Publication type:

Article

1H MRS-visible lipids accumulate during apoptosis of lymphoma cells in vitro and in vivo.

Published in:

Magnetic Resonance in Medicine, 2005, v. 54, n. 1, p. 43, doi. 10.1002/mrm.20529

By:

Schmitz, Jonathan E.;
Kettunen, Mikko I.;
Hu, De-En;
Brindle, Kevin M.

Publication type:

Article

Induction of apoptosis in two mammalian cell lines results in increased levels of fructose-1,6-Bisphosphate and CDP-choline as determined by 31P MRS.

Published in:

Magnetic Resonance in Medicine, 1998, v. 40, n. 3, p. 411, doi. 10.1002/mrm.1910400311

By:

Williams, Shane N. O.;
Anthony, Maria L.;
Brindle, Kevin M.

Publication type:

Article

31P NMR measurements of the effects of unsaturated fatty acids on cellular phospholipid metabolism.

Published in:

Magnetic Resonance in Medicine, 1996, v. 35, n. 4, p. 481, doi. 10.1002/mrm.1910350406

By:

Gillham, Helen;
Brindle, Kevin M.

Publication type:

Article

Phospholipid bilayer contribution to 31P NMR spectra in vivo.

Published in:

Magnetic Resonance in Medicine, 1989, v. 12, n. 2, p. 282, doi. 10.1002/mrm.1910120218

By:

Murphy, Elizabeth J.;
Rajagopalan, Bheeshma;
Brindle, Kevin M.;
Radda, George K.

Publication type:

Article

Mapping of oxygen tension and cell distribution in a hollow-fiber bioreactor using magnetic resonance imaging.

Published in:

Biotechnology & Bioengineering, 1997, v. 56, n. 1, p. 56, doi. 10.1002/(SICI)1097-0290(19971005)56:1<56::AID-BIT6>3.0.CO;2-U

By:

Williams, Shane N. O.;
Callies, Rainer M.;
Brindle, Kevin M.

Publication type:

Article

1H NMR-based metabolite profiling as a potential selection tool for breeding passive resistance against Fusarium head blight (FHB) in wheat.

Published in:

Molecular Plant Pathology, 2007, v. 8, n. 4, p. 401, doi. 10.1111/j.1364-3703.2007.00400.x

By:

BROWNE, ROY A.;
BRINDLE, KEVIN M.

Publication type:

Article

Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 4, p. 1286, doi. 10.1002/anie.201509858

By:

Neves, André A.;
Wainman, Yéléna A.;
Wright, Alan;
Kettunen, Mikko I.;
Rodrigues, Tiago B.;
McGuire, Sarah;
Hu, De-En;
Bulat, Flaviu;
Geninatti Crich, Simonetta;
Stöckmann, Henning;
Leeper, Finian J.;
Brindle, Kevin M.

Publication type:

Article

Back Cover: Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging (Angew. Chem. Int. Ed. 4/2016).

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 4, p. 1566, doi. 10.1002/anie.201511259

By:

Neves, André A.;
Wainman, Yéléna A.;
Wright, Alan;
Kettunen, Mikko I.;
Rodrigues, Tiago B.;
McGuire, Sarah;
Hu, De-En;
Bulat, Flaviu;
Geninatti Crich, Simonetta;
Stöckmann, Henning;
Leeper, Finian J.;
Brindle, Kevin M.

Publication type:

Article

Translation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-024-03831-z

By:

McAteer, Martina A.;
McGowan, Daniel R.;
Cook, Gary J. R.;
Leung, Hing Y.;
Ng, Tony;
O'Connor, James P. B.;
Aloj, Luigi;
Barnes, Anna;
Blower, Phil J.;
Brindle, Kevin M.;
Braun, John;
Buckley, Craig;
Darian, Daniel;
Evans, Paul;
Goh, Vicky;
Grainger, David;
Green, Carol;
Hall, Matt G.;
Harding, Thomas A.;
Hines, Catherine D. G.

Publication type:

Article

Optimisation of Animal Handing and Timing of 2-deoxy-2-[18F]fluoro-D-glucose PET Tumour Imaging in Mice.

Published in:

Molecular Imaging & Biology, 2024, v. 26, n. 6, p. 965, doi. 10.1007/s11307-024-01956-4

By:

Hesketh, Richard L.;
Lewis, David Y.;
Brindle, Kevin M.

Publication type:

Article

New Horizons in Hyperpolarized 13C MRI.

Published in:

Molecular Imaging & Biology, 2024, v. 26, n. 2, p. 222, doi. 10.1007/s11307-023-01888-5

By:

Chaumeil, Myriam M.;
Bankson, James A.;
Brindle, Kevin M.;
Epstein, Shdema;
Gallagher, Ferdia A.;
Grashei, Martin;
Guglielmetti, Caroline;
Kaggie, Joshua D.;
Keshari, Kayvan R.;
Knecht, Stephan;
Laustsen, Christoffer;
Schmidt, Andreas B.;
Vigneron, Daniel;
Yen, Yi-Fen;
Schilling, Franz

Publication type:

Article

CARS based label-free assay for assessment of drugs by monitoring lipid droplets in tumour cells.

Published in:

Journal of Biophotonics, 2014, v. 7, n. 11/12, p. 906, doi. 10.1002/jbio.201300110

By:

Steuwe, Christian;
Patel, Imran I.;
Ul-Hasan, Mahmud;
Schreiner, Alexander;
Boren, Joan;
Brindle, Kevin M.;
Reichelt, Stefanie;
Mahajan, Sumeet

Publication type:

Article

Magnetic resonance imaging of tumor glycolysis using hyperpolarized 13C-labeled glucose.

Published in:

Nature Medicine, 2014, v. 20, n. 1, p. 93, doi. 10.1038/nm.3416

By:

Rodrigues, Tiago B;
Serrao, Eva M;
Kennedy, Brett W C;
Hu, De-En;
Kettunen, Mikko I;
Brindle, Kevin M

Publication type:

Article

Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus.

Published in:

Nature Medicine, 2012, v. 18, n. 2, p. 315, doi. 10.1038/nm.2616

By:

Bird-Lieberman, Elizabeth L;
Neves, André A;
Lao-Sirieix, Pierre;
O'Donovan, Maria;
Novelli, Marco;
Lovat, Laurence B;
Eng, William S;
Mahal, Lara K;
Brindle, Kevin M;
Fitzgerald, Rebecca C

Publication type:

Article

Erratum: Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy.

Published in:

2007

By:

Day, Sam E;
Kettunen, Mikko I;
Gallagher, Ferdia A;
Hu, De-En;
Lerche, Mathilde;
Wolber, Jan;
Golman, Klaes;
Ardenkjaer-Larsen, Jan Henrik;
Brindle, Kevin M

Publication type:

Correction Notice

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy.

Published in:

Nature Medicine, 2007, v. 13, n. 11, p. 1382, doi. 10.1038/nm1650

By:

Day, Sam E.;
Kettunen, Mikko I.;
Gallagher, Ferdia A.;
De-En Hu;
Lerche, Mathilde;
Wolber, Jan;
Golman, Klaes;
Ardenkjaer-Larsen, Jan Henrik;
Brindle, Kevin M.

Publication type:

Article

Proton NMR analysis of plasma is a weak predictor of coronary artery disease.

Published in:

Nature Medicine, 2006, v. 12, n. 6, p. 705, doi. 10.1038/nm1432

By:

Kirschenlohr, Heide L.;
Griffin, Julian L.;
Clarke, Sarah C.;
Rhydwen, Ranyl;
Grace, Andrew A.;
Schofield, Peter M.;
Brindle, Kevin M.;
Metcalfe, James C.

Publication type:

Article

Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent.

Published in:

Nature Medicine, 2001, v. 7, n. 11, p. 1241, doi. 10.1038/nm1101-1241

By:

Zhao, Ming;
Beauregard, Daniel A.;
Loizou, Louiza;
Davletov, Basbek;
Brindle, Kevin M.

Publication type:

Article

Rücktitelbild: Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging (Angew. Chem. 4/2016).

Published in:

Angewandte Chemie, 2016, v. 128, n. 4, p. 1592, doi. 10.1002/ange.201511259

By:

Neves, André A.;
Wainman, Yéléna A.;
Wright, Alan;
Kettunen, Mikko I.;
Rodrigues, Tiago B.;
McGuire, Sarah;
Hu, De‐En;
Bulat, Flaviu;
Geninatti Crich, Simonetta;
Stöckmann, Henning;
Leeper, Finian J.;
Brindle, Kevin M.

Publication type:

Article

Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging.

Published in:

Angewandte Chemie, 2016, v. 128, n. 4, p. 1308, doi. 10.1002/ange.201509858

By:

Neves, André A.;
Wainman, Yéléna A.;
Wright, Alan;
Kettunen, Mikko I.;
Rodrigues, Tiago B.;
McGuire, Sarah;
Hu, De‐En;
Bulat, Flaviu;
Geninatti Crich, Simonetta;
Stöckmann, Henning;
Leeper, Finian J.;
Brindle, Kevin M.

Publication type:

Article

Hyperpolarized 13C spectroscopic imaging using single‐shot 3D sequences with unpaired adiabatic refocusing pulses.

Published in:

NMR in Biomedicine, 2018, v. 31, n. 11, p. N.PAG, doi. 10.1002/nbm.4004

By:

Wang, Jiazheng;
Hesketh, Richard L.;
Wright, Alan J.;
Brindle, Kevin M.

Publication type:

Article

Increased hyperpolarized [1‐13C] lactate production in a model of joint inflammation is not accompanied by tissue acidosis as assessed using hyperpolarized 13C‐labelled bicarbonate.

Published in:

NMR in Biomedicine, 2018, v. 31, n. 4, p. 1, doi. 10.1002/nbm.3892

By:

Wright, Alan J.;
Husson, Zoé M. A.;
Hu, De‐En;
Callejo, Gerard;
Brindle, Kevin M.;
Smith, Ewan St. John

Publication type:

Article

Sub‐minute kinetics of human red cell fumarase: 1H spin‐echo NMR spectroscopy and 13C rapid‐dissolution dynamic nuclear polarization.

Published in:

NMR in Biomedicine, 2018, v. 31, n. 3, p. 1, doi. 10.1002/nbm.3870

By:

Shishmarev, Dmitry;
Wright, Alan J.;
Rodrigues, Tiago B.;
Pileio, Giuseppe;
Stevanato, Gabriele;
Brindle, Kevin M.;
Kuchel, Philip W.

Publication type:

Article

A referenceless Nyquist ghost correction workflow for echo planar imaging of hyperpolarized [1‐13C]pyruvate and [1‐13C]lactate.

Published in:

NMR in Biomedicine, 2018, v. 31, n. 2, p. 1, doi. 10.1002/nbm.3866

By:

Wang, Jiazheng;
Wright, Alan J.;
Hesketh, Richard L.;
Hu, De‐en;
Brindle, Kevin M.

Publication type:

Article

Effects of fasting on serial measurements of hyperpolarized [1-13C]pyruvate metabolism in tumors.

Published in:

NMR in Biomedicine, 2016, v. 29, n. 8, p. 1048, doi. 10.1002/nbm.3568

By:

Serrao, Eva M.;
Rodrigues, Tiago B.;
Gallagher, Ferdia A.;
Kettunen, Mikko I.;
Kennedy, Brett W. C.;
Vowler, Sarah L.;
Burling, Keith A.;
Brindle, Kevin M.

Publication type:

Article

A comparison of quantitative methods for clinical imaging with hyperpolarized 13C-pyruvate.

Published in:

NMR in Biomedicine, 2016, v. 29, n. 4, p. 387, doi. 10.1002/nbm.3468

By:

Daniels, Charlie J.;
McLean, Mary A.;
Schulte, Rolf F.;
Robb, Fraser J.;
Gill, Andrew B.;
McGlashan, Nicholas;
Graves, Martin J.;
Schwaiger, Markus;
Lomas, David J.;
Brindle, Kevin M.;
Gallagher, Ferdia A.

Publication type:

Article

Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse.

Published in:

NMR in Biomedicine, 2013, v. 26, n. 12, p. 1696, doi. 10.1002/nbm.3005

By:

Marco‐Rius, Irene;
Tayler, Michael C. D.;
Kettunen, Mikko I.;
Larkin, Timothy J.;
Timm, Kerstin N.;
Serrao, Eva M.;
Rodrigues, Tiago B.;
Pileio, Giuseppe;
Ardenkjaer‐Larsen, Jan Henrik;
Levitt, Malcolm H.;
Brindle, Kevin M.

Publication type:

Article

Imaging pH with hyperpolarized 13C.

Published in:

NMR in Biomedicine, 2011, v. 24, n. 8, p. 1006, doi. 10.1002/nbm.1742

By:

Gallagher, Ferdia A.;
Kettunen, Mikko I.;
Brindle, Kevin M.

Publication type:

Article

Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4-acetic acid, assessed using MRI and MRS.

Published in:

NMR in Biomedicine, 2002, v. 15, n. 2, p. 99, doi. 10.1002/nbm.723

By:

Beauregard, Daniel A.;
Pedley, R. Barbara;
Hill, Sally A.;
Brindle, Kevin M.

Publication type:

Article

Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-13C]Pyruvate.

Published in:

Frontiers in Oncology, 2016, p. 1, doi. 10.3389/fonc.2016.00059

By:

Serrao, Eva M.;
Brindle, Kevin M.;
Serkova, Natalie Julie;
Nelson, Sarah

Publication type:

Article

Studies of metabolic control using NMR and molecular genetics.

Published in:

Journal of Molecular Recognition, 1997, v. 10, n. 4, p. 182, doi. 10.1002/(SICI)1099-1352(199707/08)10:4<182::AID-JMR363>3.0.CO;2-9

By:

Brindle, Kevin M.;
Fulton, Sandra M.;
Gillham, Helen;
Williams, Simon-Peter

Publication type:

Article

Enzymology in vivo using NMR and molecular genetics.

Published in:

Journal of Molecular Recognition, 1993, v. 6, n. 4, p. 159, doi. 10.1002/jmr.300060404

By:

Brindle, Kevin M.;
Fulton, Alexandra M.;
Williams, Simon-Peter

Publication type:

Article