Works by Brindle, K.

Results: 38

Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways.
Published in:
Cell Cycle, 2011, v. 10, n. 2, p. 212, doi. 10.4161/cc.10.2.14542
By:
- Kasper, Lawryn H.;
- Thomas, Mary C.;
- Zambetti, Gerard P.;
- Brindle, Paul K.
Publication type:
Article
Mammalian Gene Expression Program Resiliency.
Published in:
Cell Cycle, 2006, v. 5, n. 2, p. 142, doi. 10.4161/cc.5.2.2353
By:
- Kasper, Lawryn H.;
- Brindle, Paul K.
Publication type:
Article
Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription.
Published in:
EMBO Journal, 2001, v. 20, n. 23, p. 6836, doi. 10.1093/emboj/20.23.6836
By:
- Nakajima, Hideaki;
- Brindle, Paul K.;
- Handa, Makoto;
- Ihle, James N.
Publication type:
Article
The appearance of neutral lipid signals in the 1H NMR spectra of a myeloma cell line correlates with the induced formation of cytoplasmic lipid droplets.
Published in:
Magnetic Resonance in Medicine, 1993, v. 29, n. 4, p. 546, doi. 10.1002/mrm.1910290418
By:
- Callies, R.;
- Sri-Pathmanathan, R. M.;
- Ferguson, D. Y. P.;
- Brindle, K. M.
Publication type:
Article
Inactivating mutations of acetyltransferase genes in B-cell lymphoma.
Published in:
Nature, 2011, v. 471, n. 7337, p. 189, doi. 10.1038/nature09730
By:
- Pasqualucci, Laura;
- Dominguez-Sola, David;
- Chiarenza, Annalisa;
- Fabbri, Giulia;
- Grunn, Adina;
- Trifonov, Vladimir;
- Kasper, Lawryn H.;
- Lerach, Stephanie;
- Hongyan Tang;
- Jing Ma;
- Rossi, Davide;
- Chadburn, Amy;
- Murty, Vundavalli V.;
- Mullighan, Charles G.;
- Gaidano, Gianluca;
- Rabadan, Raul;
- Brindle, Paul K.;
- Dalla-Favera, Riccardo
Publication type:
Article
CREBBP mutations in relapsed acute lymphoblastic leukaemia.
Published in:
Nature, 2011, v. 471, n. 7337, p. 235, doi. 10.1038/nature09727
By:
- Mullighan, Charles G.;
- Jinghui Zhang;
- Kasper, Lawryn H.;
- Lerach, Stephanie;
- Payne-Turner, Debbie;
- Phillips, Letha A.;
- Heatley, Sue L.;
- Holmfeldt, Linda;
- Collins-Underwood, J. Racquel;
- Jing Ma;
- Buetow, Kenneth H.;
- Ching-Hon Pui;
- Baker, Sharyn D.;
- Brindle, Paul K.;
- Downing, James R.
Publication type:
Article
Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen, Germany.
Published in:
2018
By:
- Bailey, D. L.;
- Pichler, B. J.;
- Gückel, B.;
- Antoch, G.;
- Barthel, H.;
- Bhujwalla, Z. M.;
- Biskup, S.;
- Biswal, S.;
- Bitzer, M.;
- Boellaard, R.;
- Braren, R. F.;
- Brendle, C.;
- Brindle, K.;
- Chiti, A.;
- la Fougère, C.;
- Gillies, R.;
- Goh, V.;
- Goyen, M.;
- Hacker, M.;
- Heukamp, L.
Publication type:
research
Towards a Successful Clinical Implementation of Fluorescence-Guided Surgery.
Published in:
Molecular Imaging & Biology, 2014, v. 16, n. 2, p. 147, doi. 10.1007/s11307-013-0707-y
By:
- Snoeks, T.;
- Driel, P.;
- Keereweer, S.;
- Aime, S.;
- Brindle, K.;
- Dam, G.;
- Löwik, C.;
- Ntziachristos, V.;
- Vahrmeijer, A.
Publication type:
Article
Editorial.
Published in:
NMR in Biomedicine, 2002, v. 15, n. 2, p. 87, doi. 10.1002/nbm.763
By:
- Brindle, K.
Publication type:
Article
Diffusion weighted imaging and magnetic resonance spectroscopy in a low flow ischaemia model due to endothelin induced vasospasm.
Published in:
NMR in Biomedicine, 2000, v. 13, n. 3, p. 154, doi. 10.1002/1099-1492(200005)13:3<154::AID-NBM620>3.0.CO;2-W
By:
- Domingo, Z.;
- Bradley, J. K.;
- Blamire, A. M.;
- Brindle, K.;
- Styles, P.;
- Rajagopalan, B.
Publication type:
Article
Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation.
Published in:
EMBO Journal, 2011, v. 30, n. 2, p. 249, doi. 10.1038/emboj.2010.318
By:
- Jin, Qihuang;
- Yu, Li-Rong;
- Wang, Lifeng;
- Zhang, Zhijing;
- Kasper, Lawryn H;
- Lee, Ji-Eun;
- Wang, Chaochen;
- Brindle, Paul K;
- Dent, Sharon Y R;
- Ge, Kai
Publication type:
Article
CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation.
Published in:
EMBO Journal, 2010, v. 29, n. 21, p. 3660, doi. 10.1038/emboj.2010.235
By:
- Kasper, Lawryn H.;
- Lerach, Stephanie;
- Jianmin Wang;
- Song Wu;
- Jeevan, Trushar;
- Brindle, Paul K.
Publication type:
Article
Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms.
Published in:
EMBO Journal, 2007, v. 26, n. 12, p. 2890, doi. 10.1038/sj.emboj.7601734
By:
- Xu, Wu;
- Kasper, Lawryn H;
- Lerach, Stephanie;
- Jeevan, Trushar;
- Brindle, Paul K
Publication type:
Article
Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.
Published in:
EMBO Journal, 2005, v. 24, n. 22, p. 3846, doi. 10.1038/sj.emboj.7600846
By:
- Kasper, Lawryn H.;
- Boussouar, Fayçal;
- Boyd, Kelli;
- Wu Xu;
- Biesen, Michelle;
- Rehg, Jerold;
- Baudino, Troy A.;
- Cleveland, John L.;
- Brindle, Paul K.
Publication type:
Article
Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation.
Published in:
Cell Death & Differentiation, 2012, v. 19, n. 9, p. 1561, doi. 10.1038/cdd.2012.34
By:
- Boren, J;
- Brindle, K M
Publication type:
Article
Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.
Published in:
PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146366
By:
- Zheng, Fei;
- Kasper, Lawryn H.;
- Bedford, David C.;
- Lerach, Stephanie;
- Teubner, Brett J. W.;
- Brindle, Paul K.
Publication type:
Article
The significance and mechanism of mitochondrial proton conductance.
Published in:
International Journal of Obesity & Related Metabolic Disorders, 1999, v. 23, p. s4, doi. 10.1038/sj.ijo.0800936
By:
- Brand, M D;
- Brindle, K M;
- Buckingham, J A;
- Harper, J A;
- Rolfe, D F S;
- Stuart, J A
Publication type:
Article
Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-Regulatory Cell Development and Function.
Published in:
Molecular & Cellular Biology, 2014, v. 34, n. 21, p. 3993, doi. 10.1128/MCB.00919-14
By:
- Yujie Liu;
- Liqing Wang;
- Rongxiang Han;
- Beier, Ulf H.;
- Akimova, Tatiana;
- Bhatti, Tricia;
- Haiyan Xiao;
- Cole, Philip A.;
- Brindle, Paul K.;
- Hancock, Wayne W.
Publication type:
Article
Analysis of 13C and 14C labeling in pyruvate and lactate in tumor and blood of lymphoma‐bearing mice injected with 13C‐ and 14C‐labeled pyruvate.
Published in:
NMR in Biomedicine, 2018, v. 31, n. 5, p. 1, doi. 10.1002/nbm.3901
By:
- Serrao, E. M.;
- Kettunen, M. I.;
- Rodrigues, T. B.;
- Lewis, D. Y.;
- Gallagher, F. A.;
- Hu, D. E.;
- Brindle, K. M.
Publication type:
Article
Watching tumours gasp and die with MRI: the promise of hyperpolarised 13C MR spectroscopic imaging.
Published in:
British Journal of Radiology, 2012, v. 85, n. 1014, p. 697, doi. 10.1259/bjr/81120511
By:
- Brindle, K.
Publication type:
Article
Abstracts of the 26th international isotope society (UK group) symposium: Synthesis & applications of labelled compounds 2017.
Published in:
Journal of Labelled Compounds & Radiopharmaceuticals, 2018, v. 61, n. 14, p. 1115, doi. 10.1002/jlcr.3641
By:
- Aboagye, E.;
- Aigbirhio, F.;
- Allott, L.;
- Anderson, E.A.;
- Artelsmair, M.;
- Audisio, D.;
- Audisio, J.;
- Bragg, R.;
- Brindle, K.;
- Bulat, F.;
- Bürli, R.;
- Carroll, L.;
- Chapdelaine, M.;
- Collins, S.;
- Cortezon‐Tamarit, F.;
- Da Pieve, C.;
- Davies, J.R.;
- Decuypere, E.;
- Defay, T.;
- DeFrees, S.
Publication type:
Article
Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015.
Published in:
Journal of Labelled Compounds & Radiopharmaceuticals, 2016, v. 59, n. 4, p. 175, doi. 10.1002/jlcr.3377
By:
- Aigbirhio, F. I.;
- Allwein, S.;
- Anwar, A.;
- Atzrodt, J.;
- Audisio, D.;
- Badman, G;
- Bakale, R.;
- Berthon, F.;
- Bragg, R.;
- Brindle, K. M.;
- Bushby, N.;
- Campos, S.;
- Cant, A. A.;
- Chan, M. Y. T.;
- Colbon, P.;
- Cornelissen, B.;
- Czarny, B.;
- Derdau, V.;
- Dive, V.;
- Dunscombe, M.
Publication type:
Article
Transcriptional regulation by an upstream repression sequence from the yeast enolase gene ENO1.
Published in:
Yeast, 1995, v. 11, n. 11, p. 1031, doi. 10.1002/yea.320111105
By:
- Carmen, Andrew A.;
- Brindle, Paul K.;
- Park, Chang Seo;
- Holland, Michael J.
Publication type:
Article
Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity.
Published in:
Nature Medicine, 2013, v. 19, n. 9, p. 1173, doi. 10.1038/nm.3286
By:
- Liu, Yujie;
- Wang, Liqing;
- Predina, Jarrod;
- Han, Rongxiang;
- Beier, Ulf H;
- Wang, Liang-Chuan S;
- Kapoor, Veena;
- Bhatti, Tricia R;
- Akimova, Tatiana;
- Singhal, Sunil;
- Brindle, Paul K;
- Cole, Philip A;
- Albelda, Steven M;
- Hancock, Wayne W
Publication type:
Article
Erratum: Proton NMR analysis of plasma is a weak predictor of coronary artery disease.
Published in:
2006
By:
- Kirschenlohr, H L;
- Griffin, J L;
- Clarke, S C;
- Rhydwen, R;
- Grace, A A;
- Schofield, P M;
- Brindle, K M;
- Metcalfe, J C
Publication type:
Correction Notice
Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate.
Published in:
2010
By:
- Witney, T. H.;
- Kettunen, M. I.;
- Hu, D.-e.;
- Gallagher, F. A.;
- Bohndiek, S. E.;
- Napolitano, R.;
- Brindle, K. M.
Publication type:
journal article
The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.
Published in:
British Journal of Cancer, 2005, v. 92, n. 9, p. 1599, doi. 10.1038/sj.bjc.6602550
By:
- Leach, M. O.;
- Brindle, K. M.;
- Evelhoch, J. L.;
- Griffiths, J. R.;
- Horsman, M. R.;
- Jackson, A.;
- Jayson, G. C.;
- Judson, I. R.;
- Knopp, M. V.;
- Maxwell, R. J.;
- McIntyre, D.;
- Padhani, A. R.;
- Price, P.;
- Rathbone, R.;
- Rustin, G. J.;
- Tofts, P. S.;
- Tozer, G. M.;
- Vennart, W.;
- Waterton, J. C.;
- Williams, S. R.
Publication type:
Article
A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.
Published in:
Nature, 2002, v. 419, n. 6908, p. 738, doi. 10.1038/nature01062
By:
- Kasper, Lawryn H.;
- Boussouar, Fayçal;
- Ney, Paul A.;
- Jackson, Carl W.;
- Rehg, Jerold;
- van Deursen, Jan M.;
- Brindle, Paul K.
Publication type:
Article
Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.
Published in:
Nucleic Acids Research, 2014, v. 42, n. 18, p. 11363, doi. 10.1093/nar/gku827
By:
- Kasper, Lawryn H.;
- Qu, Chunxu;
- Obenauer, John C.;
- McGoldrick, Daniel J.;
- Brindle, Paul K.
Publication type:
Article
Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.
Published in:
Nucleic Acids Research, 2013, v. 41, n. 22, p. 10199, doi. 10.1093/nar/gkt824
By:
- Wolf, Louise;
- Harrison, Wilbur;
- Huang, Jie;
- Xie, Qing;
- Xiao, Ningna;
- Sun, Jian;
- Kong, Lingkun;
- Lachke, Salil A.;
- Kuracha, Murali R.;
- Govindarajan, Venkatesh;
- Brindle, Paul K.;
- Ashery-Padan, Ruth;
- Beebe, David C.;
- Overbeek, Paul A.;
- Cvekl, Ales
Publication type:
Article
Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 23, p. 6128, doi. 10.1523/JNEUROSCI.0296-07.2007
By:
- Vecsey, Christopher G.;
- Hawk, Joshua D.;
- Lattal, K. Matthew;
- Stein, Joel M.;
- Fabian, Sara A.;
- Attner, Michelle A.;
- Cabrera, Sara M.;
- McDonough, Conor B.;
- Brindle, Paul K.;
- Abel, Ted;
- Wood, Marcelo A.
Publication type:
Article
T-Cells Null for the MED23 Subunit of Mediator Express Decreased Levels of KLF2 and Inefficiently Populate the Peripheral Lymphoid Organs.
Published in:
PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102076
By:
- Kasper, Lawryn H.;
- Fukuyama, Tomofusa;
- Brindle, Paul K.
Publication type:
Article
Genetic Interaction between Mutations in c-Myb and the KIX Domains of CBP and p300 Affects Multiple Blood Cell Lineages and Influences Both Gene Activation and Repression.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082684
By:
- Kasper, Lawryn H.;
- Fukuyama, Tomofusa;
- Lerach, Stephanie;
- Chang, Yunchao;
- Xu, Wu;
- Wu, Song;
- Boyd, Kelli L.;
- Brindle, Paul K.
Publication type:
Article
Early detection of tumour immune-rejection using magnetic resonance imaging.
Published in:
2003
By:
- Hu, D-E;
- Beauregard, D A;
- Bearchell, M C;
- Thomsen, L L;
- Brindle, K M
Publication type:
journal article
Combretastatin-A4 disrupts neovascular development in non-neoplastic tissue.
Published in:
British Journal of Cancer, 2001, v. 84, n. 6, p. 832, doi. 10.1054/bjoc.2000.1653
By:
- Griggs, J;
- Hesketh, R;
- Smith, G A;
- Brindle, K M;
- Metcalfe, J C;
- Thomas, G A;
- Williams, E D
Publication type:
Article
The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.
Published in:
Diabetes, 2018, v. 67, n. 3, p. 412, doi. 10.2337/db17-0237
By:
- Chi Kin Wong;
- Wade-Vallance, Adam K.;
- Luciani, Dan S.;
- Brindle, Paul K.;
- Lynn, Francis C.;
- Gibson, William T.
Publication type:
Article
Histone Acetyltransferase CBP Is Vital To Demarcate Conventional and Innate CD8+ T-Cell Development.
Published in:
Molecular & Cellular Biology, 2009, v. 29, n. 14, p. 7, doi. 10.1128/MCB.01598-08
By:
- Fukuyama, Tomofusa;
- Kasper, Lawryn H.;
- Boussouar, Fayçal;
- Jeevan, Trushar;
- van Deursen, Jan;
- Brindle, Paul K.
Publication type:
Article
Conditional Knockout Mice Reveal Distinct Functions for the Global Transcriptional Coactivators CBP and p300 in T-Cell Development.
Published in:
Molecular & Cellular Biology, 2006, v. 26, n. 3, p. 6, doi. 10.1128/MCB.26.3.789-809.2006
By:
- Kasper, Lawryn H.;
- Fukuyama, Tomofusa;
- Biesen, Michelle A.;
- Boussouar, Fayçal;
- Tong, Caili;
- De Pauw, Antoine;
- Murray, Peter J.;
- Van Deursen, Jan M. A.;
- Brindle, Paul K.
Publication type:
Article

Works by Brindle, K.

Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways.

Mammalian Gene Expression Program Resiliency.

Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription.

The appearance of neutral lipid signals in the <sup>1</sup>H NMR spectra of a myeloma cell line correlates with the induced formation of cytoplasmic lipid droplets.

Inactivating mutations of acetyltransferase genes in B-cell lymphoma.

CREBBP mutations in relapsed acute lymphoblastic leukaemia.

Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen, Germany.

Towards a Successful Clinical Implementation of Fluorescence-Guided Surgery.

Editorial.

Diffusion weighted imaging and magnetic resonance spectroscopy in a low flow ischaemia model due to endothelin induced vasospasm.

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation.

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation.

Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms.

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation.

Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.

The significance and mechanism of mitochondrial proton conductance.

Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3<sup>+</sup> T-Regulatory Cell Development and Function.

Analysis of <sup>13</sup>C and <sup>14</sup>C labeling in pyruvate and lactate in tumor and blood of lymphoma‐bearing mice injected with <sup>13</sup>C‐ and <sup>14</sup>C‐labeled pyruvate.

Watching tumours gasp and die with MRI: the promise of hyperpolarised <sup>13</sup>C MR spectroscopic imaging.

Abstracts of the 26th international isotope society (UK group) symposium: Synthesis & applications of labelled compounds 2017.

Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015.

Transcriptional regulation by an upstream repression sequence from the yeast enolase gene ENO1.

Inhibition of p300 impairs Foxp3<sup>+</sup> T regulatory cell function and promotes antitumor immunity.

Erratum: Proton NMR analysis of plasma is a weak predictor of coronary artery disease.

Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate.

The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.

Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation.

T-Cells Null for the MED23 Subunit of Mediator Express Decreased Levels of KLF2 and Inefficiently Populate the Peripheral Lymphoid Organs.

Genetic Interaction between Mutations in c-Myb and the KIX Domains of CBP and p300 Affects Multiple Blood Cell Lineages and Influences Both Gene Activation and Repression.

Early detection of tumour immune-rejection using magnetic resonance imaging.

Combretastatin-A4 disrupts neovascular development in non-neoplastic tissue.

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

Histone Acetyltransferase CBP Is Vital To Demarcate Conventional and Innate CD8<sup>+</sup> T-Cell Development.

Conditional Knockout Mice Reveal Distinct Functions for the Global Transcriptional Coactivators CBP and p300 in T-Cell Development.