Works matching AU Brindle, K.

Results: 38

Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate.

Published in:

2010

By:

Witney, T. H.;
Kettunen, M. I.;
Hu, D.-e.;
Gallagher, F. A.;
Bohndiek, S. E.;
Napolitano, R.;
Brindle, K. M.

Publication type:

journal article

Analysis of 13C and 14C labeling in pyruvate and lactate in tumor and blood of lymphoma‐bearing mice injected with 13C‐ and 14C‐labeled pyruvate.

Published in:

NMR in Biomedicine, 2018, v. 31, n. 5, p. 1, doi. 10.1002/nbm.3901

By:

Serrao, E. M.;
Kettunen, M. I.;
Rodrigues, T. B.;
Lewis, D. Y.;
Gallagher, F. A.;
Hu, D. E.;
Brindle, K. M.

Publication type:

Article

Editorial.

Published in:

NMR in Biomedicine, 2002, v. 15, n. 2, p. 87, doi. 10.1002/nbm.763

By:

Brindle, K.

Publication type:

Article

Diffusion weighted imaging and magnetic resonance spectroscopy in a low flow ischaemia model due to endothelin induced vasospasm.

Published in:

NMR in Biomedicine, 2000, v. 13, n. 3, p. 154, doi. 10.1002/1099-1492(200005)13:3<154::AID-NBM620>3.0.CO;2-W

By:

Domingo, Z.;
Bradley, J. K.;
Blamire, A. M.;
Brindle, K.;
Styles, P.;
Rajagopalan, B.

Publication type:

Article

The appearance of neutral lipid signals in the 1H NMR spectra of a myeloma cell line correlates with the induced formation of cytoplasmic lipid droplets.

Published in:

Magnetic Resonance in Medicine, 1993, v. 29, n. 4, p. 546, doi. 10.1002/mrm.1910290418

By:

Callies, R.;
Sri-Pathmanathan, R. M.;
Ferguson, D. Y. P.;
Brindle, K. M.

Publication type:

Article

The significance and mechanism of mitochondrial proton conductance.

Published in:

International Journal of Obesity & Related Metabolic Disorders, 1999, v. 23, p. s4, doi. 10.1038/sj.ijo.0800936

By:

Brand, M D;
Brindle, K M;
Buckingham, J A;
Harper, J A;
Rolfe, D F S;
Stuart, J A

Publication type:

Article

Transcriptional regulation by an upstream repression sequence from the yeast enolase gene ENO1.

Published in:

Yeast, 1995, v. 11, n. 11, p. 1031, doi. 10.1002/yea.320111105

By:

Carmen, Andrew A.;
Brindle, Paul K.;
Park, Chang Seo;
Holland, Michael J.

Publication type:

Article

Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 23, p. 6128, doi. 10.1523/JNEUROSCI.0296-07.2007

By:

Vecsey, Christopher G.;
Hawk, Joshua D.;
Lattal, K. Matthew;
Stein, Joel M.;
Fabian, Sara A.;
Attner, Michelle A.;
Cabrera, Sara M.;
McDonough, Conor B.;
Brindle, Paul K.;
Abel, Ted;
Wood, Marcelo A.

Publication type:

Article

The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.

Published in:

British Journal of Cancer, 2005, v. 92, n. 9, p. 1599, doi. 10.1038/sj.bjc.6602550

By:

Leach, M. O.;
Brindle, K. M.;
Evelhoch, J. L.;
Griffiths, J. R.;
Horsman, M. R.;
Jackson, A.;
Jayson, G. C.;
Judson, I. R.;
Knopp, M. V.;
Maxwell, R. J.;
McIntyre, D.;
Padhani, A. R.;
Price, P.;
Rathbone, R.;
Rustin, G. J.;
Tofts, P. S.;
Tozer, G. M.;
Vennart, W.;
Waterton, J. C.;
Williams, S. R.

Publication type:

Article

Early detection of tumour immune-rejection using magnetic resonance imaging.

Published in:

2003

By:

Hu, D-E;
Beauregard, D A;
Bearchell, M C;
Thomsen, L L;
Brindle, K M

Publication type:

journal article

Combretastatin-A4 disrupts neovascular development in non-neoplastic tissue.

Published in:

British Journal of Cancer, 2001, v. 84, n. 6, p. 832, doi. 10.1054/bjoc.2000.1653

By:

Griggs, J;
Hesketh, R;
Smith, G A;
Brindle, K M;
Metcalfe, J C;
Thomas, G A;
Williams, E D

Publication type:

Article

Abstracts of the 26th international isotope society (UK group) symposium: Synthesis & applications of labelled compounds 2017.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2018, v. 61, n. 14, p. 1115, doi. 10.1002/jlcr.3641

By:

Aboagye, E.;
Aigbirhio, F.;
Allott, L.;
Anderson, E.A.;
Artelsmair, M.;
Audisio, D.;
Audisio, J.;
Bragg, R.;
Brindle, K.;
Bulat, F.;
Bürli, R.;
Carroll, L.;
Chapdelaine, M.;
Collins, S.;
Cortezon‐Tamarit, F.;
Da Pieve, C.;
Davies, J.R.;
Decuypere, E.;
Defay, T.;
DeFrees, S.

Publication type:

Article

Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2016, v. 59, n. 4, p. 175, doi. 10.1002/jlcr.3377

By:

Aigbirhio, F. I.;
Allwein, S.;
Anwar, A.;
Atzrodt, J.;
Audisio, D.;
Badman, G;
Bakale, R.;
Berthon, F.;
Bragg, R.;
Brindle, K. M.;
Bushby, N.;
Campos, S.;
Cant, A. A.;
Chan, M. Y. T.;
Colbon, P.;
Cornelissen, B.;
Czarny, B.;
Derdau, V.;
Dive, V.;
Dunscombe, M.

Publication type:

Article

Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146366

By:

Zheng, Fei;
Kasper, Lawryn H.;
Bedford, David C.;
Lerach, Stephanie;
Teubner, Brett J. W.;
Brindle, Paul K.

Publication type:

Article

Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen, Germany.

Published in:

2018

By:

Bailey, D. L.;
Pichler, B. J.;
Gückel, B.;
Antoch, G.;
Barthel, H.;
Bhujwalla, Z. M.;
Biskup, S.;
Biswal, S.;
Bitzer, M.;
Boellaard, R.;
Braren, R. F.;
Brendle, C.;
Brindle, K.;
Chiti, A.;
la Fougère, C.;
Gillies, R.;
Goh, V.;
Goyen, M.;
Hacker, M.;
Heukamp, L.

Publication type:

research

Towards a Successful Clinical Implementation of Fluorescence-Guided Surgery.

Published in:

Molecular Imaging & Biology, 2014, v. 16, n. 2, p. 147, doi. 10.1007/s11307-013-0707-y

By:

Snoeks, T.;
Driel, P.;
Keereweer, S.;
Aime, S.;
Brindle, K.;
Dam, G.;
Löwik, C.;
Ntziachristos, V.;
Vahrmeijer, A.

Publication type:

Article

Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways.

Published in:

Cell Cycle, 2011, v. 10, n. 2, p. 212, doi. 10.4161/cc.10.2.14542

By:

Kasper, Lawryn H.;
Thomas, Mary C.;
Zambetti, Gerard P.;
Brindle, Paul K.

Publication type:

Article

Mammalian Gene Expression Program Resiliency.

Published in:

Cell Cycle, 2006, v. 5, n. 2, p. 142, doi. 10.4161/cc.5.2.2353

By:

Kasper, Lawryn H.;
Brindle, Paul K.

Publication type:

Article

Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-Regulatory Cell Development and Function.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 21, p. 3993, doi. 10.1128/MCB.00919-14

By:

Yujie Liu;
Liqing Wang;
Rongxiang Han;
Beier, Ulf H.;
Akimova, Tatiana;
Bhatti, Tricia;
Haiyan Xiao;
Cole, Philip A.;
Brindle, Paul K.;
Hancock, Wayne W.

Publication type:

Article

Histone Acetyltransferase CBP Is Vital To Demarcate Conventional and Innate CD8+ T-Cell Development.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 14, p. 7, doi. 10.1128/MCB.01598-08

By:

Fukuyama, Tomofusa;
Kasper, Lawryn H.;
Boussouar, Fayçal;
Jeevan, Trushar;
van Deursen, Jan;
Brindle, Paul K.

Publication type:

Article

Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation.

Published in:

Cell Death & Differentiation, 2012, v. 19, n. 9, p. 1561, doi. 10.1038/cdd.2012.34

By:

Boren, J;
Brindle, K M

Publication type:

Article

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 18, p. 11363, doi. 10.1093/nar/gku827

By:

Kasper, Lawryn H.;
Qu, Chunxu;
Obenauer, John C.;
McGoldrick, Daniel J.;
Brindle, Paul K.

Publication type:

Article

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 22, p. 10199, doi. 10.1093/nar/gkt824

By:

Wolf, Louise;
Harrison, Wilbur;
Huang, Jie;
Xie, Qing;
Xiao, Ningna;
Sun, Jian;
Kong, Lingkun;
Lachke, Salil A.;
Kuracha, Murali R.;
Govindarajan, Venkatesh;
Brindle, Paul K.;
Ashery-Padan, Ruth;
Beebe, David C.;
Overbeek, Paul A.;
Cvekl, Ales

Publication type:

Article

Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity.

Published in:

Nature Medicine, 2013, v. 19, n. 9, p. 1173, doi. 10.1038/nm.3286

By:

Liu, Yujie;
Wang, Liqing;
Predina, Jarrod;
Han, Rongxiang;
Beier, Ulf H;
Wang, Liang-Chuan S;
Kapoor, Veena;
Bhatti, Tricia R;
Akimova, Tatiana;
Singhal, Sunil;
Brindle, Paul K;
Cole, Philip A;
Albelda, Steven M;
Hancock, Wayne W

Publication type:

Article

Erratum: Proton NMR analysis of plasma is a weak predictor of coronary artery disease.

Published in:

2006

By:

Kirschenlohr, H L;
Griffin, J L;
Clarke, S C;
Rhydwen, R;
Grace, A A;
Schofield, P M;
Brindle, K M;
Metcalfe, J C

Publication type:

Correction Notice

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation.

Published in:

EMBO Journal, 2011, v. 30, n. 2, p. 249, doi. 10.1038/emboj.2010.318

By:

Jin, Qihuang;
Yu, Li-Rong;
Wang, Lifeng;
Zhang, Zhijing;
Kasper, Lawryn H;
Lee, Ji-Eun;
Wang, Chaochen;
Brindle, Paul K;
Dent, Sharon Y R;
Ge, Kai

Publication type:

Article

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation.

Published in:

EMBO Journal, 2010, v. 29, n. 21, p. 3660, doi. 10.1038/emboj.2010.235

By:

Kasper, Lawryn H.;
Lerach, Stephanie;
Jianmin Wang;
Song Wu;
Jeevan, Trushar;
Brindle, Paul K.

Publication type:

Article

Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms.

Published in:

EMBO Journal, 2007, v. 26, n. 12, p. 2890, doi. 10.1038/sj.emboj.7601734

By:

Xu, Wu;
Kasper, Lawryn H;
Lerach, Stephanie;
Jeevan, Trushar;
Brindle, Paul K

Publication type:

Article

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

Published in:

EMBO Journal, 2005, v. 24, n. 22, p. 3846, doi. 10.1038/sj.emboj.7600846

By:

Kasper, Lawryn H.;
Boussouar, Fayçal;
Boyd, Kelli;
Wu Xu;
Biesen, Michelle;
Rehg, Jerold;
Baudino, Troy A.;
Cleveland, John L.;
Brindle, Paul K.

Publication type:

Article

Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription.

Published in:

EMBO Journal, 2001, v. 20, n. 23, p. 6836, doi. 10.1093/emboj/20.23.6836

By:

Nakajima, Hideaki;
Brindle, Paul K.;
Handa, Makoto;
Ihle, James N.

Publication type:

Article

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

Published in:

Diabetes, 2018, v. 67, n. 3, p. 412, doi. 10.2337/db17-0237

By:

Chi Kin Wong;
Wade-Vallance, Adam K.;
Luciani, Dan S.;
Brindle, Paul K.;
Lynn, Francis C.;
Gibson, William T.

Publication type:

Article

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

Published in:

Nature, 2002, v. 419, n. 6908, p. 738, doi. 10.1038/nature01062

By:

Kasper, Lawryn H.;
Boussouar, Fayçal;
Ney, Paul A.;
Jackson, Carl W.;
Rehg, Jerold;
van Deursen, Jan M.;
Brindle, Paul K.

Publication type:

Article

T-Cells Null for the MED23 Subunit of Mediator Express Decreased Levels of KLF2 and Inefficiently Populate the Peripheral Lymphoid Organs.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102076

By:

Kasper, Lawryn H.;
Fukuyama, Tomofusa;
Brindle, Paul K.

Publication type:

Article

Genetic Interaction between Mutations in c-Myb and the KIX Domains of CBP and p300 Affects Multiple Blood Cell Lineages and Influences Both Gene Activation and Repression.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082684

By:

Kasper, Lawryn H.;
Fukuyama, Tomofusa;
Lerach, Stephanie;
Chang, Yunchao;
Xu, Wu;
Wu, Song;
Boyd, Kelli L.;
Brindle, Paul K.

Publication type:

Article

Inactivating mutations of acetyltransferase genes in B-cell lymphoma.

Published in:

Nature, 2011, v. 471, n. 7337, p. 189, doi. 10.1038/nature09730

By:

Pasqualucci, Laura;
Dominguez-Sola, David;
Chiarenza, Annalisa;
Fabbri, Giulia;
Grunn, Adina;
Trifonov, Vladimir;
Kasper, Lawryn H.;
Lerach, Stephanie;
Hongyan Tang;
Jing Ma;
Rossi, Davide;
Chadburn, Amy;
Murty, Vundavalli V.;
Mullighan, Charles G.;
Gaidano, Gianluca;
Rabadan, Raul;
Brindle, Paul K.;
Dalla-Favera, Riccardo

Publication type:

Article

CREBBP mutations in relapsed acute lymphoblastic leukaemia.

Published in:

Nature, 2011, v. 471, n. 7337, p. 235, doi. 10.1038/nature09727

By:

Mullighan, Charles G.;
Jinghui Zhang;
Kasper, Lawryn H.;
Lerach, Stephanie;
Payne-Turner, Debbie;
Phillips, Letha A.;
Heatley, Sue L.;
Holmfeldt, Linda;
Collins-Underwood, J. Racquel;
Jing Ma;
Buetow, Kenneth H.;
Ching-Hon Pui;
Baker, Sharyn D.;
Brindle, Paul K.;
Downing, James R.

Publication type:

Article

Watching tumours gasp and die with MRI: the promise of hyperpolarised 13C MR spectroscopic imaging.

Published in:

British Journal of Radiology, 2012, v. 85, n. 1014, p. 697, doi. 10.1259/bjr/81120511

By:

Brindle, K.

Publication type:

Article

Conditional Knockout Mice Reveal Distinct Functions for the Global Transcriptional Coactivators CBP and p300 in T-Cell Development.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 3, p. 6, doi. 10.1128/MCB.26.3.789-809.2006

By:

Kasper, Lawryn H.;
Fukuyama, Tomofusa;
Biesen, Michelle A.;
Boussouar, Fayçal;
Tong, Caili;
De Pauw, Antoine;
Murray, Peter J.;
Van Deursen, Jan M. A.;
Brindle, Paul K.

Publication type:

Article

Works matching AU Brindle, K.

Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate.

Analysis of <sup>13</sup>C and <sup>14</sup>C labeling in pyruvate and lactate in tumor and blood of lymphoma‐bearing mice injected with <sup>13</sup>C‐ and <sup>14</sup>C‐labeled pyruvate.

Editorial.

Diffusion weighted imaging and magnetic resonance spectroscopy in a low flow ischaemia model due to endothelin induced vasospasm.

The appearance of neutral lipid signals in the <sup>1</sup>H NMR spectra of a myeloma cell line correlates with the induced formation of cytoplasmic lipid droplets.

The significance and mechanism of mitochondrial proton conductance.

Transcriptional regulation by an upstream repression sequence from the yeast enolase gene ENO1.

Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation.

The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.

Early detection of tumour immune-rejection using magnetic resonance imaging.

Combretastatin-A4 disrupts neovascular development in non-neoplastic tissue.

Abstracts of the 26th international isotope society (UK group) symposium: Synthesis & applications of labelled compounds 2017.

Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015.

Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.

Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen, Germany.

Towards a Successful Clinical Implementation of Fluorescence-Guided Surgery.

Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways.

Mammalian Gene Expression Program Resiliency.

Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3<sup>+</sup> T-Regulatory Cell Development and Function.

Histone Acetyltransferase CBP Is Vital To Demarcate Conventional and Innate CD8<sup>+</sup> T-Cell Development.

Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation.

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.

Inhibition of p300 impairs Foxp3<sup>+</sup> T regulatory cell function and promotes antitumor immunity.

Erratum: Proton NMR analysis of plasma is a weak predictor of coronary artery disease.

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation.

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation.

Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms.

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription.

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

T-Cells Null for the MED23 Subunit of Mediator Express Decreased Levels of KLF2 and Inefficiently Populate the Peripheral Lymphoid Organs.

Genetic Interaction between Mutations in c-Myb and the KIX Domains of CBP and p300 Affects Multiple Blood Cell Lineages and Influences Both Gene Activation and Repression.

Inactivating mutations of acetyltransferase genes in B-cell lymphoma.

CREBBP mutations in relapsed acute lymphoblastic leukaemia.

Watching tumours gasp and die with MRI: the promise of hyperpolarised <sup>13</sup>C MR spectroscopic imaging.

Conditional Knockout Mice Reveal Distinct Functions for the Global Transcriptional Coactivators CBP and p300 in T-Cell Development.