Works by Brightling, Christopher E.

Results: 88
    1

    Incidence of diabetes mellitus following hospitalisation for COVID‐19 in the United Kingdom: A prospective observational study.

    Published in:
    Diabetes, Obesity & Metabolism, 2025, v. 27, n. 2, p. 767, doi. 10.1111/dom.16071
    By:
    • Tyrer, Freya;
    • Gharibzadeh, Safoora;
    • Gillies, Clare;
    • Lawson, Claire;
    • Routen, Ash;
    • Islam, Nazrul;
    • Razieh, Cameron;
    • Zaccardi, Francesco;
    • Yates, Tom;
    • Davies, Melanie J.;
    • Brightling, Christopher E.;
    • Chalmers, James D.;
    • Docherty, Annemarie B.;
    • Elneima, Omer;
    • Evans, Rachael A.;
    • Greening, Neil J.;
    • Harris, Victoria C.;
    • Harrison, Ewen M.;
    • Ho, Ling‐Pei;
    • Horsley, Alex
    Publication type:
    Article
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    DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19.

    Published in:
    Experimental Physiology, 2024, v. 109, n. 8, p. 1274, doi. 10.1113/EP091590
    By:
    • Gupta, Ayushman;
    • Nicholas, Rosemary;
    • McGing, Jordan J.;
    • Nixon, Aline V.;
    • Mallinson, Joanne E.;
    • McKeever, Tricia M.;
    • Bradley, Christopher R.;
    • Piasecki, Mathew;
    • Cox, Eleanor F.;
    • Bonnington, James;
    • Lord, Janet M.;
    • Brightling, Christopher E.;
    • Evans, Rachael A.;
    • Hall, Ian P.;
    • Francis, Susan T.;
    • Greenhaff, Paul L.;
    • Bolton, Charlotte E.
    Publication type:
    Article
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    The different phenotypes of COPD.

    Published in:
    British Medical Bulletin, 2021, v. 137, n. 1, p. 82, doi. 10.1093/bmb/ldaa043
    By:
    • Yousuf, Ahmed;
    • McAuley, Hamish;
    • Elneima, Omer;
    • Brightling, Christopher E
    Publication type:
    Article
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    Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes.

    Published in:
    2022
    By:
    • Reddel, Helen K.;
    • Bacharier, Leonard B.;
    • Bateman, Eric D.;
    • Brightling, Christopher E.;
    • Brusselle, Guy G.;
    • Buhl, Roland;
    • Cruz, Alvaro A.;
    • Duijts, Liesbeth;
    • Drazen, Jeffrey M.;
    • FitzGerald, J. Mark;
    • Fleming, Louise J.;
    • Inoue, Hiromasa;
    • Ko, Fanny W.;
    • Krishnan, Jerry A.;
    • Levy, Mark L.;
    • Lin, Jiangtao;
    • Mortimer, Kevin;
    • Pitrez, Paulo M.;
    • Sheikh, Aziz;
    • Yorgancioglu, Arzu A.
    Publication type:
    journal article
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    Global Initiative for Asthma (GINA) Strategy 2021 - Executive Summary and Rationale for Key Changes.

    Published in:
    2022
    By:
    • Reddel, Helen K.;
    • Bacharier, Leonard B.;
    • Bateman, Eric D.;
    • Brightling, Christopher E.;
    • Brusselle, Guy G.;
    • Buhl, Roland;
    • Cruz, Alvaro A.;
    • Duijts, Liesbeth;
    • Drazen, Jeffrey M.;
    • FitzGerald, J. Mark;
    • Fleming, Louise J.;
    • Inoue, Hiromasa;
    • Ko, Fanny W.;
    • Krishnan, Jerry A.;
    • Levy, Mark L.;
    • Lin, Jiangtao;
    • Mortimer, Kevin;
    • Pitrez, Paulo M.;
    • Sheikh, Aziz;
    • Yorgancioglu, Arzu A.
    Publication type:
    Chart/Diagram/Graph
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    Inflammatory Endotype-associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis.

    Published in:
    2021
    By:
    • Zhang Wang;
    • Locantore, Nicholas;
    • Haldar, Koirobi;
    • Ramsheh, Mohammadali Yavari;
    • Beech, Augusta S.;
    • Wei Ma;
    • Brown, James R.;
    • Tal-Singer, Ruth;
    • Barer, Michael R.;
    • Bafadhel, Mona;
    • Donaldson, Gavin C.;
    • Wedzicha, Jadwiga A.;
    • Singh, Dave;
    • Wilkinson, Tom M. A.;
    • Miller, Bruce E.;
    • Brightling, Christopher E.;
    • Wang, Zhang;
    • Ma, Wei
    Publication type:
    journal article
    15

    Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease.

    Published in:
    2020
    By:
    • Singh, Dave;
    • Bafadhel, Mona;
    • Brightling, Christopher E.;
    • Sciurba, Frank C.;
    • Curtis, Jeffrey L.;
    • Martinez, Fernando J.;
    • Pasquale, Cara B.;
    • Merrill, Debora D.;
    • Metzdorf, Norbert;
    • Petruzzelli, Stefano;
    • Tal-Singer, Ruth;
    • Compton, Christopher;
    • Rennard, Stephen;
    • Martin, Ubaldo J.;
    • COPD Foundation Eosinophil Working Group
    Publication type:
    journal article
    16

    Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease Is Enhanced by Nrf2 Agonists.

    Published in:
    2018
    By:
    • Bewley, Martin A;
    • Budd, Richard C;
    • Ryan, Eilise;
    • Cole, Joby;
    • Collini, Paul;
    • Marshall, Jennifer;
    • Kolsum, Umme;
    • Beech, Gussie;
    • Emes, Richard D;
    • Tcherniaeva, Irina;
    • Berbers, Guy A M;
    • Walmsley, Sarah R;
    • Donaldson, Gavin;
    • Wedzicha, Jadwiga A;
    • Kilty, Iain;
    • Rumsey, William;
    • Sanchez, Yolanda;
    • Brightling, Christopher E;
    • Donnelly, Louise E;
    • Barnes, Peter J
    Publication type:
    journal article
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    The sputum microbiome is distinct between COPD and health, independent of smoking history.

    Published in:
    2020
    By:
    • Haldar, Koirobi;
    • George, Leena;
    • Wang, Zhang;
    • Mistry, Vijay;
    • Ramsheh, Mohammadali Yavari;
    • Free, Robert C.;
    • John, Catherine;
    • Reeve, Nicola F.;
    • Miller, Bruce E.;
    • Tal-Singer, Ruth;
    • Webb, Adam J.;
    • Brookes, Anthony J.;
    • Tobin, Martin D.;
    • Singh, Dave;
    • Donaldson, Gavin C.;
    • Wedzicha, Jadwiga A.;
    • Brown, James R.;
    • Barer, Michael R.;
    • Brightling, Christopher E.
    Publication type:
    journal article
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    Nociceptin/orphanin FQ (N/OFQ) modulates immunopathology and airway hyperresponsiveness representing a novel target for the treatment of asthma.

    Published in:
    2016
    By:
    • Singh, Shailendra R;
    • Sullo, Nikol;
    • Matteis, Maria;
    • Spaziano, Giuseppe;
    • McDonald, John;
    • Saunders, Ruth;
    • Woodman, Lucy;
    • Urbanek, Konrad;
    • De Angelis, Antonella;
    • De Palma, Raffaele;
    • Berair, Rachid;
    • Pancholi, Mitesh;
    • Mistry, Vijay;
    • Rossi, Francesco;
    • Guerrini, Remo;
    • Calò, Girolamo;
    • D'Agostino, Bruno;
    • Brightling, Christopher E;
    • Lambert, David G;
    • Calò, Girolamo
    Publication type:
    journal article
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    A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial.

    Published in:
    2018
    By:
    • Hanratty, Catherine E.;
    • Matthews, John G.;
    • Arron, Joseph R.;
    • Choy, David F.;
    • Pavord, Ian D.;
    • Bradding, P.;
    • Brightling, Christopher E.;
    • Chaudhuri, Rekha;
    • Cowan, Douglas C.;
    • Djukanovic, Ratko;
    • Gallagher, Nicola;
    • Fowler, Stephen J.;
    • Hardman, Tim C.;
    • Harrison, Tim;
    • Holweg, Cécile T.;
    • Howarth, Peter H.;
    • Lordan, James;
    • Mansur, Adel H.;
    • Menzies-Gow, Andrew;
    • Mosesova, Sofia
    Publication type:
    journal article
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    Temporal Assessment of Airway Remodeling in Severe Asthma Using Quantitative Computed Tomography.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2015, v. 191, n. 1, p. 107, doi. 10.1164/rccm.201406-1128le
    By:
    • Gupta, Sumit;
    • Hartley, Ruth;
    • Singapuri, Amisha;
    • Hargadon, Beverly;
    • Monteiro, William;
    • Pavord, Ian D.;
    • Sousa, Ana R.;
    • Marshall, Richard P.;
    • Subramanian, Deepak;
    • Parr, David;
    • Entwisle, James J.;
    • Siddiqui, Salman;
    • Raj, Vimal;
    • Brightling, Christopher E.
    Publication type:
    Article
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    IgE Sensitization to Aspergillus fumigatus Is Associate with Reduced Lung Function in Asthma.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2010, v. 182, n. 11, p. 1362, doi. 10.1164/rccm.201001-0087OC
    By:
    • Fairs, Abbie;
    • Agbetile, Joshua;
    • Hargadon, Beverley;
    • Bourne, Michelle;
    • Monteiro, William R.;
    • Brightling, Christopher E.;
    • Bradding, Peter;
    • Green, Ruth H.;
    • Mutalithas, Kugathasan;
    • Desai, Dhananjay;
    • Pavord, Ian D.;
    • Wardlaw, Andrew J.;
    • Pashley, Catherine H.
    Publication type:
    Article
    36

    Cluster analysis and clinical asthma phenotypes.

    Published in:
    2008
    By:
    • Haldar P;
    • Pavord ID;
    • Shaw DE;
    • Berry MA;
    • Thomas M;
    • Brightling CE;
    • Wardlaw AJ;
    • Green RH;
    • Haldar, Pranab;
    • Pavord, Ian D;
    • Shaw, Dominic E;
    • Berry, Michael A;
    • Thomas, Michael;
    • Brightling, Christopher E;
    • Wardlaw, Andrew J;
    • Green, Ruth H
    Publication type:
    journal article
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    Antiinflammatory Effects of the Phosphodiesterase-4 Inhibitor Cilomilast (Ariflo) in Chronic Obstructive Pulmonary Disease.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2003, v. 168, n. 8, p. 976, doi. 10.1164/rccm.200212-1490OC
    By:
    • Gamble, Elizabeth;
    • Grootendorst, Diana C.;
    • Brightling, Christopher E.;
    • Troy, Susannah;
    • Yusheng Qiu;
    • Jie Zhu;
    • Parker, Debbie;
    • Matin, Dean;
    • Majumdar, Swati;
    • Vignola, Antonio M.;
    • Kroegel, Claus;
    • Morell, Ferran;
    • Hansel, Trevor T.;
    • Rennard, Stephen I.;
    • Compton, Christopher;
    • Amit, Ohad;
    • Tat, Tri;
    • Edelson, Jeffrey;
    • Pavord, Ian D.;
    • Rabe, Klaus F.
    Publication type:
    Article
    42

    Anti-inflammatory effects of the phosphodiesterase 4 inhibitor cilomilast (Ariflo) in COPD.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2003, v. 168, n. 8, p. 1, doi. 10.1164/rccm.200212-1490oc
    By:
    • Gamble, Elizabeth;
    • Grootendorst, Diana C.;
    • Brightling, Christopher E.;
    • Troy, Susannah;
    • Yusheng Qiu;
    • Jie Zhu;
    • Parker, Debbie;
    • Matin, Dean;
    • Majumdar, Swati;
    • Vignola, Antonio M.;
    • Kroegel, Claus;
    • Morell, Ferran;
    • Hansel, Trevor T.;
    • Rennard, Stephen I.;
    • Compton, Christopher;
    • Amit, Ohad;
    • Tat, Tri;
    • Edelson, Jeffrey;
    • Pavord, Ian D.;
    • Rabe, Klaus F.
    Publication type:
    Article
    43

    Biologic Drugs: A New Target Therapy in COPD?

    Published in:
    COPD: Journal of Chronic Obstructive Pulmonary Disease, 2018, v. 15, n. 2, p. 99, doi. 10.1080/15412555.2018.1437897
    By:
    • Yousuf, Ahmed;
    • Brightling, Christopher E
    Publication type:
    Article
    44

    High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls.

    Published in:
    Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-56618-1
    By:
    • Thun, Gian-Andri;
    • Derdak, Sophia;
    • Castro-Giner, Francesc;
    • Apunte-Ramos, Katherine;
    • Águeda, Lidia;
    • Wjst, Matthias;
    • Boland, Anne;
    • Deleuze, Jean-François;
    • Kolsum, Umme;
    • Heiss-Neumann, Marion S.;
    • Nowinski, Adam;
    • Gorecka, Dorota;
    • Hohlfeld, Jens M.;
    • Welte, Tobias;
    • Brightling, Christopher E.;
    • Parr, David G.;
    • Prasse, Antje;
    • Müller-Quernheim, Joachim;
    • Greulich, Timm;
    • Stendardo, Mariarita
    Publication type:
    Article
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    Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42284-5
    By:
    • Williams, Alexander T.;
    • Chen, Jing;
    • Coley, Kayesha;
    • Batini, Chiara;
    • Izquierdo, Abril;
    • Packer, Richard;
    • Abner, Erik;
    • Kanoni, Stavroula;
    • Shepherd, David J.;
    • Free, Robert C.;
    • Hollox, Edward J.;
    • Brunskill, Nigel J.;
    • Ntalla, Ioanna;
    • Reeve, Nicola;
    • Brightling, Christopher E.;
    • Venn, Laura;
    • Adams, Emma;
    • Bee, Catherine;
    • Wallace, Susan E.;
    • Pareek, Manish
    Publication type:
    Article
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    Multi-omic meta-analysis identifies functional signatures of airway microbiome in chronic obstructive pulmonary disease.

    Published in:
    ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2020, v. 14, n. 11, p. 2748, doi. 10.1038/s41396-020-0727-y
    By:
    • Wang, Zhang;
    • Yang, Yuqiong;
    • Yan, Zhengzheng;
    • Liu, Haiyue;
    • Chen, Boxuan;
    • Liang, Zhenyu;
    • Wang, Fengyan;
    • Miller, Bruce E.;
    • Tal-Singer, Ruth;
    • Yi, Xinzhu;
    • Li, Jintian;
    • Stampfli, Martin R.;
    • Zhou, Hongwei;
    • Brightling, Christopher E.;
    • Brown, James R.;
    • Wu, Martin;
    • Chen, Rongchang;
    • Shu, Wensheng
    Publication type:
    Article
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