Works matching AU Bretz, Frank

Results: 145

MR imaging of lung parenchyma at 0.2 T: evaluation of imaging techniques, comparative study with chest radiography and interobserver analysis.

Published in:

2004

By:

Abolmaali, Nasreddin D.;
Schmitt, Jan;
Krauss, Sabine;
Bretz, Frank;
Deimling, Michael;
Jacobi, Volkmar;
Vogl, Thomas J.

Publication type:

journal article

Efficient Two-Sample Designs for Microarray Experiments with Biological Replications.

Published in:

In Silico Biology, 2004, v. 4, n. 4, p. 461, doi. 10.3233/isb-00148

By:

Landgrebe, Jobst;
Bretz, Frank;
Brunner, Edgar

Publication type:

Article

Rejoinder to Commentaries on the "Monitoring OS in Pivotal Trials in Indolent Cancers" Article.

Published in:

Statistics in Biopharmaceutical Research, 2025, v. 17, n. 2, p. 179, doi. 10.1080/19466315.2025.2483111

By:

Fleming, Thomas R.;
Hampson, Lisa V.;
Bharani-Dharan, Bharani;
Bretz, Frank;
Chakravartty, Arunava;
Coroller, Thibaud;
Koukouli, Evanthia;
Wittes, Janet;
Yateman, Nigel;
Zuber, Emmanuel

Publication type:

Article

Monitoring Overall Survival in Pivotal Trials in Indolent Cancers.

Published in:

Statistics in Biopharmaceutical Research, 2025, v. 17, n. 2, p. 161, doi. 10.1080/19466315.2024.2365648

By:

Fleming, Thomas R.;
Hampson, Lisa V.;
Bharani-Dharan, Bharani;
Bretz, Frank;
Chakravartty, Arunava;
Coroller, Thibaud;
Koukouli, Evanthia;
Wittes, Janet;
Yateman, Nigel;
Zuber, Emmanuel

Publication type:

Article

Rejoinder.

Published in:

Statistics in Biopharmaceutical Research, 2024, v. 16, n. 4, p. 425, doi. 10.1080/19466315.2024.2394456

By:

Uschner, Diane;
Sverdlov, Oleksandr;
Carter, Kerstine;
Chipman, Jonathan J.;
Kuznetsova, Olga;
Renteria, Jone;
Lane, Adam;
Barker, Chris;
Geller, Nancy L.;
Proschan, Michael;
Posch, Martin;
Tarima, Sergey;
Bretz, Frank;
Rosenberger, William F.

Publication type:

Article

Using Randomization Tests to Address Disruptions in Clinical Trials: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions.

Published in:

Statistics in Biopharmaceutical Research, 2024, v. 16, n. 4, p. 405, doi. 10.1080/19466315.2023.2257894

By:

Uschner, Diane;
Sverdlov, Oleksandr;
Carter, Kerstine;
Chipman, Jonathan;
Kuznetsova, Olga;
Renteria, Jone;
Lane, Adam;
Barker, Chris;
Geller, Nancy;
Proschan, Michael;
Posch, Martin;
Tarima, Sergey;
Bretz, Frank;
Rosenberger, William F.

Publication type:

Article

The Role of Statistical Thinking in Biopharmaceutical Research.

Published in:

Statistics in Biopharmaceutical Research, 2023, v. 15, n. 3, p. 458, doi. 10.1080/19466315.2023.2224259

By:

Bretz, Frank;
Greenhouse, Joel B.

Publication type:

Article

Clinical and Statistical Perspectives on the ICH E9(R1) Estimand Framework Implementation.

Published in:

Statistics in Biopharmaceutical Research, 2023, v. 15, n. 3, p. 554, doi. 10.1080/19466315.2022.2081601

By:

Ionan, Alexei C.;
Paterniti, Miya;
Mehrotra, Devan V.;
Scott, John;
Ratitch, Bohdana;
Collins, Sylva;
Gomatam, Shanti;
Nie, Lei;
Rufibach, Kaspar;
Bretz, Frank

Publication type:

Article

Rejoinder: Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions.

Published in:

Statistics in Biopharmaceutical Research, 2023, v. 15, n. 1, p. 119, doi. 10.1080/19466315.2022.2162958

By:

Van Lancker, Kelly;
Tarima, Sergey;
Bartlett, Jonathan;
Bauer, Madeline;
Bharani-Dharan, Bharani;
Bretz, Frank;
Flournoy, Nancy;
Michiels, Hege;
Parra, Camila Olarte;
Rosenberger, James L;
Cro, Suzie

Publication type:

Article

Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions.

Published in:

Statistics in Biopharmaceutical Research, 2023, v. 15, n. 1, p. 94, doi. 10.1080/19466315.2022.2094459

By:

Van Lancker, Kelly;
Tarima, Sergey;
Bartlett, Jonathan;
Bauer, Madeline;
Bharani-Dharan, Bharani;
Bretz, Frank;
Flournoy, Nancy;
Michiels, Hege;
Olarte Parra, Camila;
Rosenberger, James L.;
Cro, Suzie

Publication type:

Article

Statistical Issues and Challenges in Clinical Trials for COVID-19 Treatments, Vaccines, Medical Devices and Diagnostics.

Published in:

2022

By:

Cooner, Freda;
Hamasaki, Toshimitsu;
Bretz, Frank;
Pennello, Gene;
Posch, Martin

Publication type:

Editorial

Editorial: Roles of Hypothesis Testing, p-Values and Decision Making in Biopharmaceutical Research.

Published in:

2021

By:

Hamasaki, Toshimitsu;
Bretz, Frank;
LaVange, Lisa M.;
Müller, Peter;
Pennello, Gene;
Pinheiro, José C.

Publication type:

Editorial

Statistics in Biopharmaceutical Research Best Papers Award.

Published in:

2021

By:

Hamasaki, Toshimitsu;
Bretz, Frank

Publication type:

Editorial

Statistical Challenges in the Conduct and Management of Ongoing Clinical Trials During the COVID-19 Pandemic.

Published in:

2020

By:

Hamasaki, Toshimitsu;
Bretz, Frank;
Cooner, Freda;
LaVange, Lisa M.;
Posch, Martin

Publication type:

Editorial

Clinical Trials Impacted by the COVID-19 Pandemic: Adaptive Designs to the Rescue?

Published in:

Statistics in Biopharmaceutical Research, 2020, v. 12, n. 4, p. 461, doi. 10.1080/19466315.2020.1799857

By:

Kunz, Cornelia Ursula;
Jörgens, Silke;
Bretz, Frank;
Stallard, Nigel;
Van Lancker, Kelly;
Xi, Dong;
Zohar, Sarah;
Gerlinger, Christoph;
Friede, Tim

Publication type:

Article

Machine learning for clinical trials in the era of COVID-19.

Published in:

Statistics in Biopharmaceutical Research, 2020, v. 12, n. 4, p. 506, doi. 10.1080/19466315.2020.1797867

By:

Zame, William R.;
Bica, Ioana;
Shen, Cong;
Curth, Alicia;
Lee, Hyun-Suk;
Bailey, Stuart;
Weatherall, James;
Wright, David;
Bretz, Frank;
van der Schaar, Mihaela

Publication type:

Article

Challenges in Assessing the Impact of the COVID-19 Pandemic on the Integrity and Interpretability of Clinical Trials.

Published in:

Statistics in Biopharmaceutical Research, 2020, v. 12, n. 4, p. 419, doi. 10.1080/19466315.2020.1788984

By:

Akacha, Mouna;
Branson, Janice;
Bretz, Frank;
Dharan, Bharani;
Gallo, Paul;
Gathmann, Insa;
Hemmings, Robert;
Jones, Julie;
Xi, Dong;
Zuber, Emmanuel

Publication type:

Article

Commentary on "Statistics at FDA: Reflections on the Past Six Years".

Published in:

Statistics in Biopharmaceutical Research, 2019, v. 11, n. 1, p. 20, doi. 10.1080/19466315.2018.1562369

By:

Bretz, Frank;
Xi, Dong

Publication type:

Article

Estimands and Their Role in Clinical Trials.

Published in:

Statistics in Biopharmaceutical Research, 2017, v. 9, n. 3, p. 268, doi. 10.1080/19466315.2017.1302358

By:

Akacha, Mouna;
Bretz, Frank;
Ohlssen, David;
Rosenkranz, Gerd;
Schmidli, Heinz

Publication type:

Article

Identifying effective and/or safe doses by stepwise confidence intervals for ratios.

Published in:

Statistics in Medicine, 2003, v. 22, n. 6, p. 847, doi. 10.1002/sim.1449

By:

Bretz, Frank;
Hothorn, Ludwig A.;
Hsu, Jason C.

Publication type:

Article

Detecting dose-response using contrasts: asymptotic power and sample size determination for binomial data.

Published in:

Statistics in Medicine, 2002, v. 21, n. 22, p. 3325, doi. 10.1002/sim.1324

By:

Bretz, Frank;
Hothorn, Ludwig A.

Publication type:

Article

Adaptivity in drug discovery and development.

Published in:

Drug Development Research, 2009, v. 70, n. 3, p. 169, doi. 10.1002/ddr.20285

By:

Bretz, Frank;
Branson, Michael;
Burman, Carl-Fredrik;
Chuang-Stein, Christy;
Coffey, Christopher S.

Publication type:

Article

Peter Krusches and Frank Bretz's contribution to the Discussion of 'Gaussian Differential Privacy' by Dong et al.

Published in:

Journal of the Royal Statistical Society: Series B (Statistical Methodology), 2022, v. 84, n. 1, p. 42, doi. 10.1111/rssb.12457

By:

Krusche, Peter;
Bretz, Frank

Publication type:

Article

Optimal designs for dose finding studies with an active control.

Published in:

Journal of the Royal Statistical Society: Series B (Statistical Methodology), 2014, v. 76, n. 1, p. 265, doi. 10.1111/rssb.12030

By:

Dette, Holger;
Kiss, Christine;
Benda, Norbert;
Bretz, Frank

Publication type:

Article

Equivalence of Regression Curves.

Published in:

Journal of the American Statistical Association, 2018, v. 113, n. 522, p. 711, doi. 10.1080/01621459.2017.1281813

By:

Dette, Holger;
Möllenhoff, Kathrin;
Volgushev, Stanislav;
Bretz, Frank

Publication type:

Article

Shortcuts for Locally Consonant Closed Test Procedures.

Published in:

Journal of the American Statistical Association, 2010, v. 105, n. 490, p. 660, doi. 10.1198/jasa.2010.tm08127

By:

Brannath, Werner;
Bretz, Frank

Publication type:

Article

Optimal Designs for Dose-Finding Studies.

Published in:

Journal of the American Statistical Association, 2008, v. 103, n. 483, p. 1225, doi. 10.1198/016214508000000427

By:

DETTE, Holger;
BRETZ, Frank;
PEPELYSHEV, Andrey;
PINHEIRO, José

Publication type:

Article

Distribution–free hyperrectangular tolerance regions for setting multivariate reference regions in laboratory medicine.

Published in:

Statistics in Medicine, 2024, v. 43, n. 8, p. 1604, doi. 10.1002/sim.10019

By:

Liu, Wei;
Bretz, Frank;
Cortina–Borja, Mario

Publication type:

Article

Confidence sets for a level set in linear regression.

Published in:

Statistics in Medicine, 2024, v. 43, n. 6, p. 1103, doi. 10.1002/sim.9996

By:

Wan, Fang;
Liu, Wei;
Bretz, Frank

Publication type:

Article

Choosing clinically interpretable summary measures and robust analytic procedures for quantifying the treatment difference in comparative clinical studies.

Published in:

2021

By:

McCaw, Zachary R.;
Lu Tian;
Jiawei Wei;
Lee Claggett, Brian;
Bretz, Frank;
Fitzmaurice, Garrett;
Lee-Jen Wei;
Tian, Lu;
Wei, Jiawei;
Claggett, Brian Lee;
Wei, Lee-Jen

Publication type:

journal article

Connecting Instrumental Variable methods for causal inference to the Estimand Framework.

Published in:

Statistics in Medicine, 2021, v. 40, n. 25, p. 5605, doi. 10.1002/sim.9143

By:

Bowden, Jack;
Bornkamp, Björn;
Glimm, Ekkehard;
Bretz, Frank

Publication type:

Article

Graphical approaches for the control of generalized error rates.

Published in:

2020

By:

Robertson, David S.;
Wason, James M. S.;
Bretz, Frank

Publication type:

journal article

Symmetric graphs for equally weighted tests, with application to the Hochberg procedure.

Published in:

2019

By:

Xi, Dong;
Bretz, Frank

Publication type:

journal article

Correction.

Published in:

2019

By:

Bretz, Frank

Publication type:

corrected article

Flexible alpha allocation strategies for confirmatory adaptive enrichment clinical trials with a prespecified subgroup.

Published in:

2018

By:

Sugitani, Toshifumi;
Posch, Martin;
Bretz, Frank;
Koenig, Franz

Publication type:

journal article

Assessing the similarity of dose response and target doses in two non-overlapping subgroups.

Published in:

2018

By:

Bretz, Frank;
Möllenhoff, Kathrin;
Dette, Holger;
Liu, Wei;
Trampisch, Matthias

Publication type:

journal article

Tutorial on statistical considerations on subgroup analysis in confirmatory clinical trials.

Published in:

2017

By:

Alosh, Mohamed;
Huque, Mohammad F.;
Bretz, Frank;
D'Agostino, Ralph B.;
D'Agostino, Ralph B Sr

Publication type:

journal article

Estimands in clinical trials - broadening the perspective.

Published in:

2017

By:

Akacha, Mouna;
Bretz, Frank;
Ruberg, Stephen

Publication type:

journal article

Comparing a stratified treatment strategy with the standard treatment in randomized clinical trials.

Published in:

2016

By:

Sun, Hong;
Bretz, Frank;
Gerke, Oke;
Vach, Werner

Publication type:

journal article

Model selection versus model averaging in dose finding studies.

Published in:

2016

By:

Schorning, Kirsten;
Bornkamp, Björn;
Bretz, Frank;
Dette, Holger

Publication type:

journal article

Multiple-Use Calibration for All Future Values and Exact Two-Sided Simultaneous Tolerance Intervals in Linear Regression.

Published in:

Journal of Computational & Graphical Statistics, 2025, v. 34, n. 1, p. 155, doi. 10.1080/10618600.2024.2359507

By:

Han, Yang;
Wang, Lingjiao;
Liu, Wei;
Bretz, Frank

Publication type:

Article

Statistical calibration for infinite many future values in linear regression: simultaneous or pointwise tolerance intervals or what else?

Published in:

Journal of the Royal Statistical Society: Series C (Applied Statistics), 2023, v. 72, n. 1, p. 37, doi. 10.1093/jrsssc/qlac004

By:

Han, Yang;
Sun, Yujia;
Wang, Lingjiao;
Liu, Wei;
Bretz, Frank

Publication type:

Article

Bayesian two-stage dose finding for cytostatic agents via model adaptation.

Published in:

Journal of the Royal Statistical Society: Series C (Applied Statistics), 2016, v. 65, n. 3, p. 465, doi. 10.1111/rssc.12129

By:

Xu, Jiajing;
Yin, Guosheng;
Ohlssen, David;
Bretz, Frank

Publication type:

Article

CRITICAL POINT AND POWER CALCULATIONS FOR THE STUDENTIZED RANGE TEST FOR GENERALLY CORRELATED MEANS.

Published in:

Journal of Statistical Computation & Simulation, 2001, v. 71, n. 2, p. 85, doi. 10.1080/00949650108812136

By:

Bretz, Frank;
Hayter, Anthony J.;
Genz, Alan

Publication type:

Article

NUMERICAL COMPUTATION OF MULTIVARIATE t-PROBABILITIES WITH APPLICATION TO POWER CALCULATION OF...

Published in:

Journal of Statistical Computation & Simulation, 1999, v. 63, n. 4, p. 361, doi. 10.1080/00949659908811962

By:

Genz, Alan;
Bretz, Frank

Publication type:

Article

Adaptive designs based on the truncated product method.

Published in:

BMC Medical Research Methodology, 2005, v. 5, p. 30, doi. 10.1186/1471-2288-5-30

By:

Neuhäuser, Markus;
Bretz, Frank

Publication type:

Article

Comparison of Exact and Resampling Based Multiple Testing Procedures.

Published in:

Communications in Statistics: Simulation & Computation, 2003, v. 32, n. 2, p. 461, doi. 10.1081/SAC-120017501

By:

Bretz, Frank;
Hothorn, Ludwig A.

Publication type:

Article

Testing for similarity of multivariate mixed outcomes using generalized joint regression models with application to efficacy-toxicity responses.

Published in:

Biometrics, 2024, v. 80, n. 3, p. 1, doi. 10.1093/biomtc/ujae077

By:

Hagemann, Niklas;
Marra, Giampiero;
Bretz, Frank;
Möllenhoff, Kathrin

Publication type:

Article

Optimal test procedures for multiple hypotheses controlling the familywise expected loss.

Published in:

Biometrics, 2023, v. 79, n. 4, p. 2781, doi. 10.1111/biom.13907

By:

Maurer, Willi;
Bretz, Frank;
Xun, Xiaolei

Publication type:

Article

Rejoinder to discussions on "Optimal test procedures for multiple hypotheses controlling the familywise expected loss".

Published in:

Biometrics, 2023, v. 79, n. 4, p. 2811, doi. 10.1111/biom.13905

By:

Maurer, Willi;
Bretz, Frank;
Xun, Xiaolei

Publication type:

Article