Works by Brennan, Eoin

Results: 26

Mitochondrial related variants associated with cardiovascular traits.

Published in:

Frontiers in Physiology, 2024, p. 1, doi. 10.3389/fphys.2024.1395371

By:

Cañadas-Garre, Marisa;
Maqueda, Joaquín J.;
Baños-Jaime, Blanca;
Hill, Claire;
Skelly, Ryan;
Cappa, Ruaidhri;
Brennan, Eoin;
Doyle, Ross;
Godson, Catherine;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

Article

Genetic variants affecting mitochondrial function provide further insights for kidney disease.

Published in:

BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10449-1

By:

Cañadas-Garre, Marisa;
Baños-Jaime, Blanca;
Maqueda, Joaquín J.;
Smyth, Laura J.;
Cappa, Ruaidhri;
Skelly, Ryan;
Hill, Claire;
Brennan, Eoin P.;
Doyle, Ross;
Godson, Catherine;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

Article

Decoding microRNA drivers in atherosclerosis.

Published in:

Bioscience Reports, 2022, v. 42, n. 7, p. 1, doi. 10.1042/BSR20212355

By:

Vartak, Tanwi;
Kumaresan, Soundharya;
Brennan, Eoin

Publication type:

Article

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes.

Published in:

PLoS Genetics, 2012, v. 8, n. 9, p. 1, doi. 10.1371/journal.pgen.1002921

By:

Sandholm, Niina;
Salem, Rany M.;
Mcknight, Amy Jayne;
Brennan, Eoin P.;
Forsblom, Carol;
Isakova, Tamara;
McKay, Gareth J.;
Williams, Winfred W.;
Sadlier, Denise M.;
Mäkinen, Ville-Petteri;
Swan, Elizabeth J.;
Palmer, Cameron;
Boright, Andrew P.;
Ahlqvist, Emma;
Deshmukh, Harshal A.;
Keller, Benjamin J.;
Huateng Huang;
Ahola, Aila J.;
Fagerholm, Emma;
Gordin, Daniel

Publication type:

Article

The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology.

Published in:

Life (2075-1729), 2020, v. 10, n. 9, p. 188, doi. 10.3390/life10090188

By:

Wilkinson, Michael;
Sinclair, Piriyah;
Dellatorre-Teixeira, Ludmilla;
Swan, Patrick;
Brennan, Eoin;
Moran, Bruce;
Wedekind, Dirk;
Downey, Paul;
Sheahan, Kieran;
Conroy, Emer;
Gallagher, William M.;
Docherty, Neil;
Roux, Carel le;
Brennan, Donal J.

Publication type:

Article

The Genetics of Diabetic Nephropathy.

Published in:

Genes, 2013, v. 4, n. 4, p. 596, doi. 10.3390/genes4040596

By:

Brennan, Eoin;
McEvoy, Caitríona;
Sadlier, Denise;
Godson, Catherine;
Martin, Finian

Publication type:

Article

Albuminuria-Related Genetic Biomarkers: Replication and Predictive Evaluation in Individuals with and without Diabetes from the UK Biobank.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 11209, doi. 10.3390/ijms241311209

By:

Cañadas-Garre, Marisa;
Kunzmann, Andrew T.;
Anderson, Kerry;
Brennan, Eoin P.;
Doyle, Ross;
Patterson, Christopher C.;
Godson, Catherine;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

Article

Diagnostic utility of genetic testing in patients undergoing renal biopsy.

Published in:

Cold Spring Harbor Molecular Case Studies, 2020, v. 6, n. 5, p. 1, doi. 10.1101/mcs.a005462

By:

Benson, Katherine A.;
Murray, Susan L.;
Doyle, Ross;
Doyle, Brendan;
Dorman, Anthony M.;
Sadlier, Denise;
Brennan, Eoin;
Large, Margaret;
Cavalleri, Gianpiero L.;
Godson, Catherine;
Conlon, Peter J.

Publication type:

Article

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity.

Published in:

Journal of Extracellular Vesicles, 2021, v. 10, n. 6, p. 1, doi. 10.1002/jev2.12084

By:

Oggero, Silvia;
Gaetano, Monica;
Marcone, Simone;
Fitzsimons, Stephen;
Pinto, Andreia L.;
Ikramova, Dinara;
Barry, Mary;
Burke, David;
Montero‐Melendez, Trinidad;
Cooper, Dianne;
Burgoyne, Thomas;
Belton, Orina;
Norling, Lucy V.;
Brennan, Eoin P.;
Godson, Catherine;
Perretti, Mauro

Publication type:

Article

Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35.

Published in:

2022

By:

Qin, Cheng Xue;
Norling, Lucy V.;
Vecchio, Elizabeth A.;
Brennan, Eoin P.;
May, Lauren T.;
Wootten, Denise;
Godson, Catherine;
Perretti, Mauro;
Ritchie, Rebecca H.

Publication type:

journal article

Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34963-6

By:

Smyth, Laura J.;
Dahlström, Emma H.;
Syreeni, Anna;
Kerr, Katie;
Kilner, Jill;
Doyle, Ross;
Brennan, Eoin;
Nair, Viji;
Fermin, Damian;
Nelson, Robert G.;
Looker, Helen C.;
Wooster, Christopher;
Andrews, Darrell;
Anderson, Kerry;
McKay, Gareth J.;
Cole, Joanne B.;
Salem, Rany M.;
Conlon, Peter J.;
Kretzler, Matthias;
Hirschhorn, Joel N.

Publication type:

Article

Dietary restriction and medical therapy drive PPARα-regulated improvements in early diabetic kidney disease in male rats.

Published in:

Clinical Science, 2022, v. 136, n. 21, p. 1485, doi. 10.1042/CS20220205

By:

Martin, William P.;
Nair, Meera;
Chuah, Yeong H. D.;
Malmodin, Daniel;
Pedersen, Anders;
Abrahamsson, Sanna;
Hutter, Michaela;
Abdelaal, Mahmoud;
Elliott, Jessie A.;
Fearon, Naomi;
Eckhardt, Hans;
Godson, Catherine;
Brennan, Eoin P.;
Fändriks, Lars;
le Roux, Carel W.;
Docherty, Neil G.

Publication type:

Article

Specialized pro-resolving mediators in diabetes: novel therapeutic strategies.

Published in:

Clinical Science, 2019, v. 133, n. 21, p. 2121, doi. 10.1042/CS20190067

By:

Brennan, Eoin P.;
Mohan, Muthukumar;
Andrews, Darrell;
Bose, Madhura;
Kantharidis, Phillip

Publication type:

Article

Medications Activating Tubular Fatty Acid Oxidation Enhance the Protective Effects of Roux-en-Y Gastric Bypass Surgery in a Rat Model of Early Diabetic Kidney Disease.

Published in:

Frontiers in Endocrinology, 2022, v. 12, p. 1, doi. 10.3389/fendo.2021.757228

By:

Martin, William P.;
Chuah, Yeong H. D.;
Abdelaal, Mahmoud;
Pedersen, Anders;
Malmodin, Daniel;
Abrahamsson, Sanna;
Hutter, Michaela;
Godson, Catherine;
Brennan, Eoin P.;
Fändriks, Lars;
le Roux, Carel W.;
Docherty, Neil G.

Publication type:

Article

Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease.

Published in:

Diabetologia, 2022, v. 65, n. 9, p. 1495, doi. 10.1007/s00125-022-05735-0

By:

Sandholm, Niina;
Cole, Joanne B.;
Nair, Viji;
Sheng, Xin;
Liu, Hongbo;
Ahlqvist, Emma;
van Zuydam, Natalie;
Dahlström, Emma H.;
Fermin, Damian;
Smyth, Laura J.;
Salem, Rany M.;
Forsblom, Carol;
Valo, Erkka;
Harjutsalo, Valma;
Brennan, Eoin P.;
McKay, Gareth J.;
Andrews, Darrell;
Doyle, Ross;
Looker, Helen C.;
Nelson, Robert G.

Publication type:

Article

Lipoxin A<sub>4</sub> improves cardiac remodeling and function in diabetes-associated cardiac dysfunction.

Published in:

Cardiovascular Diabetology, 2024, v. 23, p. 1, doi. 10.1186/s12933-024-02501-x

By:

Fu, Ting;
Mohan, Muthukumar;
Bose, Madhura;
Brennan, Eoin P.;
Kiriazis, Helen;
Deo, Minh;
Nowell, Cameron J.;
Godson, Catherine;
Cooper, Mark E.;
Zhao, Peishen;
Kemp-Harper, Barbara K.;
Woodman, Owen L.;
Ritchie, Rebecca H.;
Kantharidis, Phillip;
Qin, Cheng Xue

Publication type:

Article

microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.576516

By:

Fitzsimons, Stephen;
Oggero, Silvia;
Bruen, Robyn;
McCarthy, Cathal;
Strowitzki, Moritz J.;
Mahon, Niall G.;
Ryan, Nicola;
Brennan, Eoin P.;
Barry, Mary;
Perretti, Mauro;
Belton, Orina

Publication type:

Article

RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis.

Published in:

2018

By:

Shinji Hagiwara;
Sourris, Karly;
Ziemann, Mark;
Wu Tieqiao;
Mohan, Muthukumar;
McClelland, Aaron D.;
Brennan, Eoin;
Forbes, Josephine;
Coughlan, Melinda;
Harcourt, Brooke;
Penfold, Sally;
Bo Wang;
Higgins, Gavin;
Pickering, Raelene;
El-Osta, Assam;
Thomas, Merlin C.;
Cooper, Mark E.;
Kantharidis, Phillip;
Hagiwara, Shinji;
Tieqiao, Wu

Publication type:

journal article

Protective Effect of let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis.

Published in:

2017

By:

Brennan, Eoin;
Bo Wang;
McClelland, Aaron;
Mohan, Muthukumar;
Marai, Mariam;
Beuscart, Ophelie;
Derouiche, Sinda;
Gray, Stephen;
Pickering, Raelene;
Tikellis, Chris;
de Gaetano, Monica;
Barry, Mary;
Belton, Orina;
Tasadaque Ali-Shah, Syed;
Guiry, Patrick;
Jandeleit-Dahm, Karin A. M.;
Cooper, Mark E.;
Godson, Catherine;
Kantharidis, Phillip;
Wang, Bo

Publication type:

journal article

Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease.

Published in:

2015

By:

Todd, Jennifer N.;
Dahlström, Emma H.;
Salem, Rany M.;
Sandholm, Niina;
Forsblom, Carol;
McKnight, Amy J.;
Maxwell, Alexander P.;
Brennan, Eoin;
Sadlier, Denise;
Godson, Catherine;
Groop, Per-Henrik;
Hirschhorn, Joel N.;
Florez, Jose C.;
FinnDiane Study Group

Publication type:

journal article

Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy.

Published in:

Diabetes, 2012, v. 61, n. 8, p. 2187, doi. 10.2337/db11-0751

By:

Williams, Winfred W.;
Salem, Rany M.;
Mcknight, Amy Jayne;
Sandholm, Niina;
Forsblom, Carol;
Taylor, Andrew;
Guiducci, Candace;
McAteer, Jarred B.;
McKay, Gareth J.;
Isakova, Tamara;
Brennan, Eoin P.;
Sadlier, Denise M.;
Palmer, Cameron;
Söderlund, Jenny;
Fagerholm, Emma;
Harjutsalo, Valma;
Lithovius, Raija;
Gordin, Daniel;
Hietala, Kustaa;
Kytö, Janne

Publication type:

Article

Treatment with lipoxin A<sub>4</sub> improves influenza A infection outcome, induces macrophage reprogramming, anti-inflammatory and pro-resolutive responses.

Published in:

Inflammation Research, 2024, v. 73, n. 11, p. 1903, doi. 10.1007/s00011-024-01939-9

By:

Rago, Flavia;
Melo, Eliza Mathias;
Miller, Leigh M.;
Duray, Alexis M.;
Batista Felix, Franciel;
Vago, Juliana Priscila;
de Faria Gonçalves, Ana Paula;
Angelo, Ana Luiza Pessoa Mendonça;
Cassali, Geovanni D.;
de Gaetano, Monica;
Brennan, Eoin;
Owen, Benjamin;
Guiry, Patrick;
Godson, Catherine;
Alcorn, John F.;
Teixeira, Mauro Martins

Publication type:

Article

NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells.

Published in:

Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00007

By:

McEvoy, Caitriona;
de Gaetano, Monica;
Giffney, Hugh E.;
Bahar, Bojlul;
Cummins, Eoin P.;
Brennan, Eoin P.;
Barry, Mary;
Belton, Orina;
Godson, Catherine G.;
Murphy, Evelyn P.;
Crean, Daniel

Publication type:

Article

Targeting cellular drivers and counter-regulators of hyperglycaemia- and transforming growth factor- β1-associated profibrotic responses in diabetic kidney disease.

Published in:

Experimental Physiology, 2014, v. 99, n. 9, p. 1154, doi. 10.1113/expphysiol.2014.078774

By:

Docherty, Neil G.;
Murphy, Madeline;
Martin, Finian;
Brennan, Eoin P.;
Godson, Catherine

Publication type:

Article

Study of micro RNA in diabetic nephropathy: Isolation, quantification and biological function.

Published in:

Nephrology, 2015, v. 20, n. 3, p. 132, doi. 10.1111/nep.12374

By:

Kantharidis, Phillip;
Hagiwara, Shinji;
Brennan, Eoin;
McClelland, Aaron D.

Publication type:

Article

Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis.

Published in:

2018

By:

Brennan, Eoin P.;
Mohan, Muthukumar;
McClelland, Aaron;
de Gaetano, Monica;
Tikellis, Christos;
Marai, Mariam;
Crean, Daniel;
Dai, Aozhi;
Beuscart, Ophelie;
Derouiche, Sinda;
Gray, Stephen P.;
Pickering, Raelene;
Tan, Sih Min;
Godson-Treacy, Molly;
Sheehan, Stephen;
Dowdall, Joseph F.;
Barry, Mary;
Belton, Orina;
Ali-Shah, Syed Tasadaque;
Guiry, Patrick J.

Publication type:

journal article