Works by Bremer, Erhard

Results: 54

Bacterial abl-like genes: production of the archaeal osmolyte $$ (N (\varepsilon ))(\text( - acetyl - ))\beta (\text( - lysine)) $$ by homologous overexpression of the yodP-kamA genes in Bacillus subtilis.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 91, n. 3, p. 689, doi. 10.1007/s00253-011-3301-8

By:

Müller, Stefan;
Hoffmann, Tamara;
Santos, Helena;
Saum, Stephan H.;
Bremer, Erhard;
Müller, Volker

Publication type:

Article

Two MarR-Type Repressors Balance Precursor Uptake and Glycine Betaine Synthesis in Bacillus subtilis to Provide Cytoprotection Against Sustained Osmotic Stress.

Published in:

Frontiers in Microbiology, 2020, v. 11, p. 1, doi. 10.3389/fmicb.2020.01700

By:

Warmbold, Bianca;
Ronzheimer, Stefanie;
Freibert, Sven-Andreas;
Seubert, Andreas;
Hoffmann, Tamara;
Bremer, Erhard

Publication type:

Article

Exploiting Substrate Promiscuity of Ectoine Hydroxylase for Regio- and Stereoselective Modification of Homoectoine.

Published in:

Frontiers in Microbiology, 2019, v. 10, p. 1, doi. 10.3389/fmicb.2019.02745

By:

Czech, Laura;
Wilcken, Sarah;
Czech, Oliver;
Linne, Uwe;
Brauner, Jarryd;
Smits, Sander H. J.;
Galinski, Erwin A.;
Bremer, Erhard

Publication type:

Article

Two evolutionary closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.

Published in:

Molecular Microbiology, 1999, v. 32, n. 1, p. 203, doi. 10.1046/j.1365-2958.1999.01354.x

By:

Kappes, Rainer M.;
Kempf, Bettina;
Kneip, Susanne;
Boch, Jens;
Meier-Wagner, Jutta;
Bremer, Erhard

Publication type:

Article

Osmoregulation of the opuE proline transport gene from Bacilus subtilis: contributions of the...

Published in:

Molecular Microbiology, 1998, v. 29, n. 1, p. 285, doi. 10.1046/j.1365-2958.1998.00929.x

By:

Spiegelhalter, Frank;
Bremer, Erhard

Publication type:

Article

Osmostress response in Bacillus subtilis: characterization of a proline uptake system (OpuE) regulated by high osmolarity and the alternative transcription factor sigma B.

Published in:

Molecular Microbiology, 1997, v. 25, n. 1, p. 175, doi. 10.1046/j.1365-2958.1997.4441809.x

By:

Von Blohn, Carsten;
Kempf, Bettina;
Kappes, Rainer M.;
Bremer, Erhard

Publication type:

Article

Structural and functional characterization of the bacterial biofilm activator RemA.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26005-4

By:

Hoffmann, Tamara;
Mrusek, Devid;
Bedrunka, Patricia;
Burchert, Fabiana;
Mais, Christopher-Nils;
Kearns, Daniel B.;
Altegoer, Florian;
Bremer, Erhard;
Bange, Gert

Publication type:

Article

The many faces of the unusual biofilm activator RemA.

Published in:

BioEssays, 2022, v. 44, n. 5, p. 1, doi. 10.1002/bies.202200009

By:

Bremer, Erhard;
Hoffmann, Tamara;
Dempwolff, Felix;
Bedrunka, Patricia;
Bange, Gert

Publication type:

Article

Masters of change.

Published in:

Biological Chemistry, 2020, v. 401, n. 12, p. 1305, doi. 10.1515/hsz-2020-0229

By:

Bremer, Erhard

Publication type:

Article

The ups and downs of ectoine: structural enzymology of a major microbial stress protectant and versatile nutrient.

Published in:

Biological Chemistry, 2020, v. 401, n. 12, p. 1443, doi. 10.1515/hsz-2020-0223

By:

Hermann, Lucas;
Mais, Christopher-Nils;
Czech, Laura;
Smits, Sander H.J.;
Bange, Gert;
Bremer, Erhard

Publication type:

Article

Guardians in a stressful world: the Opu family of compatible solute transporters from Bacillus subtilis.

Published in:

Biological Chemistry, 2017, v. 398, n. 2, p. 193, doi. 10.1515/hsz-2016-0265

By:

Hoffmann, Tamara;
Bremer, Erhard

Publication type:

Article

Structural analysis of the choline-binding protein ChoX in a semi-closed and ligand-free conformation.

Published in:

Biological Chemistry, 2009, v. 390, n. 11, p. 1163, doi. 10.1515/BC.2009.113

By:

Oswald, Christine;
Smits, Sander H. J.;
Höing, Marina;
Bremer, Erhard;
Schmitt, Lutz

Publication type:

Article

Overproduction, crystallization and X-ray diffraction data analysis of ectoine synthase from the cold-adapted marine bacterium Sphingopyxis alaskensis.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 8, p. 1027, doi. 10.1107/S2053230X15011115

By:

Kobus, Stefanie;
Widderich, Nils;
Hoeppner, Astrid;
Bremer, Erhard;
Smits, Sander H. J.

Publication type:

Article

The MocR/GabR Ectoine and Hydroxyectoine Catabolism Regulator EnuR: Inducer and DNA Binding.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.764731

By:

Hermann, Lucas;
Dempwolff, Felix;
Steinchen, Wieland;
Freibert, Sven-Andreas;
Smits, Sander H. J.;
Seubert, Andreas;
Bremer, Erhard

Publication type:

Article

Enhanced Glutamate Synthesis and Export by the Thermotolerant Emerging Industrial Workhorse Bacillus methanolicus in Response to High Osmolarity.

Published in:

Frontiers in Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fmicb.2021.640980

By:

Frank, Christine;
Hoffmann, Tamara;
Zelder, Oskar;
Felle, Max F.;
Bremer, Erhard

Publication type:

Article

Guilty by association: Importers, exporters and MscS‐type mechanosensitive channels encoded in biosynthetic gene clusters for the stress‐protectant ectoine.

Published in:

Environmental Microbiology, 2022, v. 24, n. 11, p. 5306, doi. 10.1111/1462-2920.16203

By:

Czech, Laura;
Gertzen, Christoph;
Smits, Sander H. J.;
Bremer, Erhard

Publication type:

Article

Cellular adaptation of Clostridioides difficile to high salinity encompasses a compatible solute‐responsive change in cell morphology.

Published in:

Environmental Microbiology, 2022, v. 24, n. 3, p. 1499, doi. 10.1111/1462-2920.15925

By:

Michel, Annika‐Marisa;
Borrero‐de Acuña, José Manuel;
Molinari, Gabriella;
Ünal, Can Murat;
Will, Sabine;
Derksen, Elisabeth;
Barthels, Stefan;
Bartram, Wiebke;
Schrader, Michel;
Rohde, Manfred;
Zhang, Hao;
Hoffmann, Tamara;
Neumann‐Schaal, Meina;
Bremer, Erhard;
Jahn, Dieter

Publication type:

Article

Impact of high salinity and the compatible solute glycine betaine on gene expression of Bacillus subtilis.

Published in:

Environmental Microbiology, 2020, v. 22, n. 8, p. 3266, doi. 10.1111/1462-2920.15087

By:

Rath, Hermann;
Sappa, Praveen K.;
Hoffmann, Tamara;
Gesell Salazar, Manuela;
Reder, Alexander;
Steil, Leif;
Hecker, Michael;
Bremer, Erhard;
Mäder, Ulrike;
Völker, Uwe

Publication type:

Article

Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes.

Published in:

Environmental Microbiology, 2018, v. 20, n. 1, p. 305, doi. 10.1111/1462-2920.13999

By:

Hoffmann, Tamara;
Warmbold, Bianca;
Smits, Sander H. J.;
Tschapek, Britta;
Ronzheimer, Stefanie;
Bashir, Abdallah;
Chen, Chiliang;
Rolbetzki, Anne;
Pittelkow, Marco;
Jebbar, Mohamed;
Seubert, Andreas;
Schmitt, Lutz;
Bremer, Erhard

Publication type:

Article

Transcriptional regulation of ectoine catabolism in response to multiple metabolic and environmental cues.

Published in:

Environmental Microbiology, 2017, v. 19, n. 11, p. 4599, doi. 10.1111/1462-2920.13924

By:

Schulz, Annina;
Hermann, Lucas;
Freibert, SvEN ‐ Andreas;
Bönig, Tobias;
Hoffmann, Tamara;
Riclea, Ramona;
Dickschat, JeroEN S.;
Heider, Johann;
Bremer, Erhard

Publication type:

Article

Synthesis of the compatible solute proline by Bacillus subtilis: point mutations rendering the osmotically controlled proHJ promoter hyperactive.

Published in:

Environmental Microbiology, 2017, v. 19, n. 9, p. 3700, doi. 10.1111/1462-2920.13870

By:

Hoffmann, Tamara;
Bleisteiner, Monika;
Sappa, Praveen Kumar;
Steil, Leif;
Mäder, Ulrike;
Völker, Uwe;
Bremer, Erhard

Publication type:

Article

Clostridium difficile: A bad bug goes into defensive mode.

Published in:

Environmental Microbiology, 2017, v. 19, n. 7, p. 2523, doi. 10.1111/1462-2920.13776

By:

Bremer, Erhard

Publication type:

Article

Feeding on compatible solutes: A substrate-induced pathway for uptake and catabolism of ectoines and its genetic control by EnuR.

Published in:

Environmental Microbiology, 2017, v. 19, n. 3, p. 926, doi. 10.1111/1462-2920.13414

By:

Schulz, Annina;
Stöveken, Nadine;
Binzen, Ina M.;
Hoffmann, Tamara;
Heider, Johann;
Bremer, Erhard

Publication type:

Article

Strangers in the archaeal world: osmostress-responsive biosynthesis of ectoine and hydroxyectoine by the marine thaumarchaeon Nitrosopumilus maritimus.

Published in:

Environmental Microbiology, 2016, v. 18, n. 4, p. 1227, doi. 10.1111/1462-2920.13156

By:

Widderich, Nils;
Czech, Laura;
Elling, Felix J.;
Könneke, Martin;
Stöveken, Nadine;
Pittelkow, Marco;
Riclea, Ramona;
Dickschat, Jeroen S.;
Heider, Johann;
Bremer, Erhard

Publication type:

Article

Abiotic stress protection by ecologically abundant dimethylsulfoniopropionate and its natural and synthetic derivatives: insights from B acillus subtilis.

Published in:

Environmental Microbiology, 2015, v. 17, n. 7, p. 2362, doi. 10.1111/1462-2920.12698

By:

Broy, Sebastian;
Chen, Chiliang;
Hoffmann, Tamara;
Brock, Nelson L.;
Nau ‐ Wagner, Gabriele;
Jebbar, Mohamed;
Smits, Sander H. J.;
Dickschat, Jeroen S.;
Bremer, Erhard

Publication type:

Article

Adaptation of B acillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi-omics perspective.

Published in:

Environmental Microbiology, 2014, v. 16, n. 6, p. 1898, doi. 10.1111/1462-2920.12438

By:

Kohlstedt, Michael;
Sappa, Praveen K.;
Meyer, Hanna;
Maaß, Sandra;
Zaprasis, Adrienne;
Hoffmann, Tamara;
Becker, Judith;
Steil, Leif;
Hecker, Michael;
Dijl, Jan Maarten;
Lalk, Michael;
Mäder, Ulrike;
Stülke, Jörg;
Bremer, Erhard;
Völker, Uwe;
Wittmann, Christoph

Publication type:

Article

Mutational activation of the RocR activator and of a cryptic rocDEF promoter bypass loss of the initial steps of proline biosynthesis in Bacillus subtilis.

Published in:

Environmental Microbiology, 2014, v. 16, n. 3, p. 701, doi. 10.1111/1462-2920.12193

By:

Zaprasis, Adrienne;
Hoffmann, Tamara;
Wünsche, Guido;
Flórez, Lope A.;
Stülke, Jörg;
Bremer, Erhard

Publication type:

Article

Role of the Extremolytes Ectoine and Hydroxyectoine as Stress Protectants and Nutrients: Genetics, Phylogenomics, Biochemistry, and Structural Analysis.

Published in:

Genes, 2018, v. 9, n. 4, p. 177, doi. 10.3390/genes9040177

By:

Czech, Laura;
Hermann, Lucas;
Stöveken, Nadine;
Richter, Alexandra A.;
Höppner, Astrid;
Smits, Sander H. J.;
Heider, Johann;
Bremer, Erhard

Publication type:

Article

Catabolism of the extremolytes ectoine and hydroxyectoine - Regulation and mechanisms.

Published in:

Studia Universitatis Babeş-Bolyai, Biologia, 2019, v. 64, n. 1, p. 113

By:

Hermann, Lucas;
Bremer, Erhard

Publication type:

Article

Making the stress-protectant ectoine: Structural and biochemical insights into the acetyltransferase EctA.

Published in:

Studia Universitatis Babeş-Bolyai, Biologia, 2019, v. 64, n. 1, p. 110

By:

Richter, Alexandra A.;
Kobus, Stefanie;
Czech, Laura;
Höppner, Astrid;
Zarzycki, Jan;
Erb, Tobias;
Lauterbach, Lukas;
Dickschat, Jeroen S.;
Bremer, Erhard;
Smits, Sander H. J.

Publication type:

Article

Synthesis, uptake and excretion of ectoines in the alpha-proteobacteria Hyphomonas neptunium and Novosphingobium sp. LH128.

Published in:

Studia Universitatis Babeş-Bolyai, Biologia, 2019, v. 64, n. 1, p. 60

By:

Czech, Laura;
Smits, Sander;
Bremer, Erhard

Publication type:

Article

The extremolytes ectoine and hydroxyectoine: import, synthesis and genetic regulation in response to osmotic stress.

Published in:

Studia Universitatis Babeş-Bolyai, Biologia, 2019, v. 64, n. 1, p. 57

By:

Bremer, Erhard

Publication type:

Article

Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151285

By:

Widderich, Nils;
Kobus, Stefanie;
Höppner, Astrid;
Riclea, Ramona;
Seubert, Andreas;
Dickschat, Jeroen S.;
Heider, Johann;
Smits, Sander H. J.;
Bremer, Erhard

Publication type:

Article

A model industrial workhorse: Bacillus subtilis strain 168 and its genome after a quarter of a century.

Published in:

Microbial Biotechnology, 2023, v. 16, n. 6, p. 1203, doi. 10.1111/1751-7915.14257

By:

Bremer, Erhard;
Calteau, Alexandra;
Danchin, Antoine;
Harwood, Colin;
Helmann, John D.;
Médigue, Claudine;
Palsson, Bernhard O.;
Sekowska, Agnieszka;
Vallenet, David;
Zuniga, Abril;
Zuniga, Cristal

Publication type:

Article

Stress‐induced activation of the proline biosynthetic pathway in Bacillus subtilis: a population‐wide and single‐cell study of the osmotically controlled proHJ promoter.

Published in:

Microbial Biotechnology, 2022, v. 15, n. 9, p. 2411, doi. 10.1111/1751-7915.14073

By:

Morawska, Luiza P.;
Detert Oude Weme, Ruud G. J.;
Frenzel, Elrike;
Dirkzwager, Maarten;
Hoffmann, Tamara;
Bremer, Erhard;
Kuipers, Oscar P.

Publication type:

Article

Compatible Solute Synthesis and Import by the Moderate Halophile Spiribacter salinus: Physiology and Genomics.

Published in:

Frontiers in Microbiology, 2018, p. 1, doi. 10.3389/fmicb.2018.00108

By:

León, María J.;
Hoffmann, Tamara;
Sánchez-Porro, Cristina;
Heider, Johann;
Ventosa, Antonio;
Bremer, Erhard

Publication type:

Article

Identification of Differentially Expressed Genes during Bacillus subtilis Spore Outgrowth in High-Salinity Environments Using RNA Sequencing.

Published in:

Frontiers in Microbiology, 2016, v. 7, p. 1, doi. 10.3389/fmicb.2016.01564

By:

Nagler, Katja;
Krawczyk, Antonina O.;
De Jong, Anne;
Madela, Kazimierz;
Hoffmann, Tamara;
Laue, Michael;
Kuipers, Oscar P.;
Bremer, Erhard;
Moeller, Ralf

Publication type:

Article

Functional overexpression and in vitro re-association of OpuA, an osmotically regulated ABC-transport complex from Bacillus subtilis

Published in:

FEBS Letters, 2005, v. 579, n. 25, p. 5765, doi. 10.1016/j.febslet.2005.09.063

By:

Horn, Carsten;
Bremer, Erhard;
Schmitt, Lutz

Publication type:

Article

Systems metabolic engineering of Corynebacterium glutamicum for production of the chemical chaperone ectoine.

Published in:

Microbial Cell Factories, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2859-12-110

By:

Becker, Judith;
Schäfer, Rudolf;
Kohlstedt, Michael;
Harder, Björn J.;
Borchert, Nicole S.;
Stöveken, Nadine;
Bremer, Erhard;
Wittmann, Christoph

Publication type:

Article

Overexpression, crystallization and preliminary X-ray crystallographic analysis of the ectoine hydroxylase from Sphingopyxis alaskensis.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 4, p. 493, doi. 10.1107/S2053230X14004798

By:

Hoeppner, Astrid;
Widderich, Nils;
Bremer, Erhard;
Smits, Sander H. J.

Publication type:

Article

Illuminating the catalytic core of ectoine synthase through structural and biochemical analysis.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-36247-w

By:

Czech, Laura;
Höppner, Astrid;
Kobus, Stefanie;
Seubert, Andreas;
Riclea, Ramona;
Dickschat, Jeroen S.;
Heider, Johann;
Smits, Sander H. J.;
Bremer, Erhard

Publication type:

Article

From substrate specificity to promiscuity: hybrid ABC transporters for osmoprotectants.

Published in:

Molecular Microbiology, 2017, v. 104, n. 5, p. 761, doi. 10.1111/mmi.13660

By:

Teichmann, Laura;
Chen, Chiliang;
Hoffmann, Tamara;
Smits, Sander H.J.;
Schmitt, Lutz;
Bremer, Erhard

Publication type:

Article

Salt-sensitivity of σ<sup>H</sup> and Spo0A prevents sporulation of B acillus subtilis at high osmolarity avoiding death during cellular differentiation.

Published in:

Molecular Microbiology, 2016, v. 100, n. 1, p. 108, doi. 10.1111/mmi.13304

By:

Widderich, Nils;
Rodrigues, Christopher D. A.;
Commichau, Fabian M.;
Fischer, Kathleen E.;
Ramirez‐Guadiana, Fernando H.;
Rudner, David Z.;
Bremer, Erhard

Publication type:

Article

The BCCT family of carriers: from physiology to crystal structure.

Published in:

Molecular Microbiology, 2010, v. 78, n. 1, p. 13, doi. 10.1111/j.1365-2958.2010.07332.x

By:

Ziegler, Christine;
Bremer, Erhard;
Krämer, Reinhard

Publication type:

Article

EctD-mediated biotransformation of the chemical chaperone ectoine into hydroxyectoine and its mechanosensitive channel-independent excretion.

Published in:

Microbial Cell Factories, 2016, v. 15, p. 1, doi. 10.1186/s12934-016-0525-4

By:

Czech, Laura;
Stöveken, Nadine;
Bremer, Erhard

Publication type:

Article

With a pinch of extra salt—Did predatory protists steal genes from their food?

Published in:

PLoS Biology, 2018, v. 16, n. 2, p. 1, doi. 10.1371/journal.pbio.2005163

By:

Czech, Laura;
Bremer, Erhard

Publication type:

Article

The cytoplasmic phosphate level has a central regulatory role in the phosphate starvation response of Caulobacter crescentus.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06469-y

By:

Billini, Maria;
Hoffmann, Tamara;
Kühn, Juliane;
Bremer, Erhard;
Thanbichler, Martin

Publication type:

Article

The GbsR Family of Transcriptional Regulators: Functional Characterization of the OpuAR Repressor.

Published in:

Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.02536

By:

Ronzheimer, Stefanie;
Warmbold, Bianca;
Arnhold, Christian;
Bremer, Erhard

Publication type:

Article

Synthesis of the Escherichia coli K-12 nucleoid-associated DNA-binding protein H-NS is subjected to growth-phase control and autoregulation.

Published in:

Molecular Microbiology, 1993, v. 8, n. 5, p. 875, doi. 10.1111/j.1365-2958.1993.tb01634.x

By:

Dersch, Petra;
Schmidt, Kerstin;
Bremer, Erhard

Publication type:

Article

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis.

Published in:

Science Signaling, 2017, v. 10, n. 475, p. 1, doi. 10.1126/scisignal.aal3011

By:

Gundlach, Jan;
Herzberg, Christina;
Kaever, Volkhard;
Gunka, Katrin;
Hoffmann, Tamara;
Weiß, Martin;
Gibhardt, Johannes;
Thürmer, Andrea;
Hertel, Dietrich;
Daniel, Rolf;
Bremer, Erhard;
Commichau, Fabian M.;
Stülke, Jörg

Publication type:

Article