Works by Brekken, Rolf A.

Results: 87

The Current State of Tumor Microenvironment-Specific Therapies for Non-Small Cell Lung Cancer.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1732, doi. 10.3390/cancers17111732

By:

Chandra, Raghav;
Ehab, Jasmina;
Hauptmann, Edward;
Gunturu, Naga Swati;
Karalis, John D.;
Kent, Daniel O.;
Heid, Christopher A.;
Reznik, Scott I.;
Sarkaria, Inderpal S.;
Huang, Huocong;
Brekken, Rolf A.;
Minna, John D.

Publication type:

Article

Tumor specific activation of the VEGF/KDR angiogenic pathway in a subset of locally advanced squamous cell head and neck carcinomas.

Published in:

Clinical & Experimental Metastasis, 2000, v. 18, n. 4, p. 313, doi. 10.1023/A:1011083121295

By:

Giatromanolaki, Alexandra;
Koukourakis, Michael;
Sivridis, Efthimios;
Thorpe, Philip;
Brekken, Rolf;
Konstantinos, Simopoulos;
Fountzilas, George;
Gatter, Kevin;
Harris, Adrian

Publication type:

Article

Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer.

Published in:

ImmunoTargets & Therapy, 2018, v. 7, p. 1, doi. 10.2147/ITT.S134834

By:

Belzile, Olivier;
Huang, Xianming;
Gong, Jian;
Carlson, Jay;
Schroit, Alan J;
Brekken, Rolf A;
Freimark, Bruce D

Publication type:

Article

Targeting TAM to Tame Pancreatic Cancer.

Published in:

Targeted Oncology, 2020, v. 15, n. 5, p. 579, doi. 10.1007/s11523-020-00751-9

By:

von Itzstein, Mitchell S.;
Burke, Michael C.;
Brekken, Rolf A.;
Aguilera, Todd A.;
Zeh, Herbert J.;
Beg, Muhammad Shaalan

Publication type:

Article

Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth.

Published in:

Nature Medicine, 2009, v. 15, n. 9, p. 1023, doi. 10.1038/nm.2018

By:

Albuquerque, Romulo J. C.;
Hayashi, Takahiko;
Won Gil Cho;
Kleinman, Mark E.;
Dridi, Sami;
Takeda, Atsunobu;
Baffi, Judit Z.;
Yamada, Kiyoshi;
Kaneko, Hiroki;
Green, Martha G.;
Chappell, Joe;
Wilting, Jörg;
Weich, Herbert A.;
Yamagami, Satoru;
Amano, Shiro;
Mizuki, Nobuhisa;
Alexander, Jonathan S.;
Peterson, Martha L.;
Brekken, Rolf A.;
Hirashima, Masanori

Publication type:

Article

Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer.

Published in:

BMC Cancer, 2011, v. 11, n. 1, p. 15, doi. 10.1186/1471-2407-11-15

By:

Awasthi, Niranjan;
Kirane, Amanda;
Schwarz, Margaret A.;
Toombs, Jason E.;
Brekken, Rolf A.;
Schwarz, Roderich E.

Publication type:

Article

The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer.

Published in:

2008

By:

Dineen SP;
Sullivan LA;
Beck AW;
Miller AF;
Carbon JG;
Mamluk R;
Wong H;
Brekken RA;
Dineen, Sean P;
Sullivan, Laura A;
Beck, Adam W;
Miller, Andrew F;
Carbon, Juliet G;
Mamluk, Roni;
Wong, Henry;
Brekken, Rolf A

Publication type:

journal article

Role of SPARC in Bone Remodeling and Cancer-Related Bone Metastasis.

Published in:

Journal of Cellular Biochemistry, 2014, v. 115, n. 1, p. 17, doi. 10.1002/jcb.24649

By:

Ribeiro, Nilza;
Sousa, Susana R.;
Brekken, Rolf A.;
Monteiro, Fernado J.

Publication type:

Article

SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity.

Published in:

Journal of Cell Biology, 2011, v. 193, n. 7, p. 1305, doi. 10.1083/jcb.201011143

By:

Rivera, Lee B.;
Brekken, Rolf A.

Publication type:

Article

Epithelial–mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib.

Published in:

Carcinogenesis, 2012, v. 33, n. 9, p. 1639, doi. 10.1093/carcin/bgs195

By:

Kirane, Amanda;
Toombs, Jason E;
Larsen, Jill E;
Ostapoff, Katherine T;
Meshaw, Kathryn R;
Zaknoen, Sara;
Brekken, Rolf A;
Burrows, Francis J

Publication type:

Article

Vascular Endothelial Growth Factor Receptor-2 Promotes the Development of the Lymphatic Vasculature.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074686

By:

Dellinger, Michael T.;
Meadows, Stryder M.;
Wynne, Katherine;
Cleaver, Ondine;
Brekken, Rolf A.

Publication type:

Article

Enhanced Heme Function and Mitochondrial Respiration Promote the Progression of Lung Cancer Cells

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063402

By:

Hooda, Jagmohan;
Cadinu, Daniela;
Alam, Md Maksudul;
Shah, Ajit;
Cao, Thai M.;
Sullivan, Laura A.;
Brekken, Rolf;
Zhang, Li

Publication type:

Article

Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFb Activation.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031384

By:

Arnold, Shanna A.;
Rivera, Lee B.;
Carbon, Juliet G.;
Toombs, Jason E.;
Chang, Chi-Lun;
Bradshaw, Amy D.;
Brekken, Rolf A.

Publication type:

Article

Phosphorylation of Akt and ERK½ Is Required for VEGFA/VEGFR2-Induced Proliferation and Migration of Lymphatic Endothelium.

Published in:

PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0028947

By:

Dellinger, Michael T.;
Brekken, Rolf A.

Publication type:

Article

r84, a Novel Therapeutic Antibody against Mouse and Human VEGF with Potent Anti-Tumor Activity and Limited Toxicity Induction.

Published in:

PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012031

By:

Sullivan, Laura A.;
Carbon, Juliet G.;
Roland, Christina L.;
Toombs, Jason E.;
Nyquist-Andersen, Mari;
Kavlie, Anita;
Schlunegger, Kyle;
Richardson, James A.;
Brekken, Rolf A.

Publication type:

Article

Oncogene Mutations, Copy Number Gains and Mutant Allele Specific Imbalance (MASI) Frequently Occur Together in Tumor Cells.

Published in:

PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007464

By:

Soh, Junichi;
Okumura, Naoki;
Lockwood, William W.;
Yamamoto, Hiromasa;
Shigematsu, Hisayuki;
Wei Zhang;
Chari, Raj;
Shames, David S.;
Ximing Tang;
MacAulay, Calum;
Varella-Garcia, Marileila;
Vooder, Tonu;
Wistuba, Ignacio I.;
Lam, Stephen;
Brekken, Rolf;
Toyooka, Shinichi;
Minna, John D.;
Lam, Wan L.;
Gazdar, Adi F.

Publication type:

Article

Intravenous delivery of the plasma fraction of stored packed erythrocytes promotes pancreatic cancer growth in immunocompetent mice.

Published in:

Cancer (0008543X), 2010, v. 116, n. 16, p. 3862, doi. 10.1002/cncr.25140

By:

Barnett, Carlton C.;
Beck, Adam W.;
Holloway, Shane E.;
Kehler, Marguerite;
Schluterman, Marie K.;
Brekken, Rolf A.;
Fleming, Jason B.;
Silliman, Christopher C.

Publication type:

Article

Rgs16 is an early marker of pancreatic ductal adenocarcinoma (842.7).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.842.7

By:

Ocal, Ozhan;
Heath, Blake;
Rivera, Lee;
Pashkov, Victor;
Swift, Galvin;
Brekken, Rolf;
Wilkie, Thomas

Publication type:

Article

Targeting interleukin-6 as a strategy to overcome stroma-induced resistance to chemotherapy in gastric cancer.

Published in:

Molecular Cancer, 2019, v. 18, n. 1, p. 1, doi. 10.1186/s12943-019-0972-8

By:

Ham, In-Hye;
Hye Jeong Oh;
Hyejin Jin;
Bae, Cheong A;
Sang-Min Jeon;
Kyeong Sook Choi;
Sang-Yong Son;
Sang-Uk Han;
Brekken, Rolf A.;
Dakeun Lee;
Hoon Hur

Publication type:

Article

PD‐L1 Immune Checkpoint Targeted Photoactivable Liposomes (iTPALs) Prime the Stroma of Pancreatic Tumors and Promote Self‐Delivery (Adv. Healthcare Mater. 19/2024).

Published in:

Advanced Healthcare Materials, 2024, v. 13, n. 19, p. 1, doi. 10.1002/adhm.202470121

By:

Bhandari, Chanda;
Moffat, Azophi;
Shah, Nimit;
Khan, Adil;
Quaye, Maxwell;
Fakhry, John;
Soma, Siddharth;
Nguyen, Austin;
Eroy, Menitte;
Malkoochi, Ashritha;
Brekken, Rolf;
Hasan, Tayyaba;
Ferruzzi, Jacopo;
Obaid, Girgis

Publication type:

Article

PD‐L1 Immune Checkpoint Targeted Photoactivable Liposomes (iTPALs) Prime the Stroma of Pancreatic Tumors and Promote Self‐Delivery.

Published in:

Advanced Healthcare Materials, 2024, v. 13, n. 19, p. 1, doi. 10.1002/adhm.202304340

By:

Bhandari, Chanda;
Moffat, Azophi;
Shah, Nimit;
Khan, Adil;
Quaye, Maxwell;
Fakhry, John;
Soma, Siddharth;
Nguyen, Austin;
Eroy, Menitte;
Malkoochi, Ashritha;
Brekken, Rolf;
Hasan, Tayyaba;
Ferruzzi, Jacopo;
Obaid, Girgis

Publication type:

Article

PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35649-9

By:

Sui, Lufei;
Wang, Suming;
Ganguly, Debolina;
El Rayes, Tyler P.;
Askeland, Cecilie;
Børretzen, Astrid;
Sim, Danielle;
Halvorsen, Ole Johan;
Knutsvik, Gøril;
Arnes, Jarle;
Aziz, Sura;
Haukaas, Svein;
Foulkes, William D.;
Bielenberg, Diane R.;
Ziemys, Arturas;
Mittal, Vivek;
Brekken, Rolf A.;
Akslen, Lars A.;
Watnick, Randolph S.

Publication type:

Article

APR-246 alone and in combination with a phosphatidylserine-targeting antibody inhibits lung metastasis of human triple-negative breast cancer cells in nude mice.

Published in:

Breast Cancer: Targets & Therapy, 2019, v. 11, p. 249, doi. 10.2147/BCTT.S208706

By:

Liang, Yayun;
Besch-Williford, Cynthia;
Cook, Matthew T;
Belenchia, Anthony;
Brekken, Rolf A;
Hyder, Salman M

Publication type:

Article

Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts.

Published in:

Cancer Biology & Therapy, 2011, v. 12, n. 7, p. 1, doi. 10.4161/cbt.12.7.15955

By:

Yu-An Zhang;
Maitra, Anirban;
Jer-Tsong Hsieh;
Rudin, Charles M.;
Peacock, Craig;
Karikari, Collins;
Brekken, Rolf A.;
Stastny, Victor;
Gao, Boning;
Girard, Luc;
Wistuba, Ignacio;
Frenkel, Eugene;
Minna, John D.;
Gazdar, Adi F.

Publication type:

Article

The angiogenic "vascular endothelial growth factor/flk-1(KDR) receptor" pathway in patients with endometrial carcinoma: prognostic and therapeutic implications.

Published in:

2001

By:

Giatromanolaki, Alexandra;
Sivridis, Efthimios;
Brekken, Rolf;
Thorpe, Philip E.;
Anastasiadis, Panagiotis;
Gatter, Kevin C.;
Harris, Adrian L.;
Koukourakis, Michael I.;
Giatromanolaki, A;
Sivridis, E;
Brekken, R;
Thorpe, P E;
Anastasiadis, P;
Gatter, K C;
Harris, A L;
Koukourakis, M I;
Tumour and Angiogenesis Research Group

Publication type:

journal article

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy.

Published in:

2014

By:

D'Amico, Gabriela;
Korhonen, Emilia A;
Anisimov, Andrey;
Zarkada, Georgia;
Holopainen, Tanja;
Hägerling, René;
Kiefer, Friedemann;
Eklund, Lauri;
Sormunen, Raija;
Elamaa, Harri;
Brekken, Rolf A;
Adams, Ralf H;
Koh, Gou Young;
Saharinen, Pipsa;
Alitalo, Kari

Publication type:

journal article

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 2, p. 824, doi. 10.1172/JCI68897

By:

D'Amico, Gabriela;
Korhonen, Emilia A.;
Anisimov, Andrey;
Zarkada, Georgia;
Holopainen, Tanja;
Hägerling, René;
Kiefer, Friedemann;
Eklund, Lauri;
Sormunen, Raija;
Elamaa, Harri;
Brekken, Rolf A.;
Adams, Ralf H.;
Gou Young Koh;
Saharinen, Pipsa;
Alitalo, Kari

Publication type:

Article

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 3, p. 1732, doi. 10.1172/JCI65385

By:

Chatterjee, Sampurna;
Heukamp, Lukas C.;
Siobal, Maike;
Schöttle, Jakob;
Wieczorek, Caroline;
Peifer, Martin;
Frasca, Davide;
Koker, Mirjam;
König, Katharina;
Meder, Lydia;
Rauh, Daniel;
Buettner, Reinhard;
Wolf, Jürgen;
Brekken, Rolf A.;
Neumaier, Bernd;
Christofori, Gerhard;
Thomas, Roman K.;
Ullrich, Roland T.

Publication type:

Article

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.

Published in:

2013

By:

Chatterjee, Sampurna;
Heukamp, Lukas C;
Siobal, Maike;
Schöttle, Jakob;
Wieczorek, Caroline;
Peifer, Martin;
Frasca, Davide;
Koker, Mirjam;
König, Katharina;
Meder, Lydia;
Rauh, Daniel;
Buettner, Reinhard;
Wolf, Jürgen;
Brekken, Rolf A;
Neumaier, Bernd;
Christofori, Gerhard;
Thomas, Roman K;
Ullrich, Roland T

Publication type:

journal article

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 4, p. 1732, doi. 10.1172/JCI65385

By:

Chatterjee, Sampurna;
Heukamp, Lukas C.;
Siobal, Maike;
Schöttle, Jakob;
Wieczorek, Caroline;
Peifer, Martin;
Frasca, Davide;
Koker, Mirjam;
König, Katharina;
Meder, Lydia;
Rauh, Daniel;
Buettner, Reinhard;
Wolf, Jürgen;
Brekken, Rolf A.;
Neumaier, Bernd;
Christofori, Gerhard;
Thomas, Roman K.;
Ullrich, Roland T.

Publication type:

Article

Loss of SPARC in bladder cancer enhances carcinogenesis and progression.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 751, doi. 10.1172/JCI64782

By:

Said, Neveen;
Frierson, Henry F.;
Sanchez-Carbayo, Marta;
Brekken, Rolf A.;
Theodorescu, Dan

Publication type:

Article

Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice.

Published in:

2010

By:

Chambliss, Ken L.;
Qian Wu;
Oltmann, Sarah;
Konaniah, Eddy S.;
Umetani, Michihisa;
Korach, Kenneth S.;
Thomas, Gail D.;
Mineo, Chieko;
Yuhanna, Ivan S.;
Sung Hoon Kim;
Madak-Erdogan, Zeynep;
Maggi, Adriana;
Dineen, Sean P.;
Roland, Christina L.;
Hui, David Y.;
Brekken, Rolf A.;
Katzenellenbogen, John A.;
Katzenellenbogen, Benita S.;
Shaul, Philip W.;
Wu, Qian

Publication type:

journal article

Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A.

Published in:

2006

By:

Nozaki, Miho;
Sakurai, Eiji;
Raisler, Brian J.;
Baffi, Judit Z.;
Witta, Jassir;
Ogura, Yuichiro;
Brekken, Rolf A.;
Sage, E. Helene;
Ambati, Balamurali K.;
Ambati, Jayakrishna

Publication type:

journal article

SPARC regulates TGF-beta1-dependent signaling in primary glomerular mesangial cells.

Published in:

Journal of Cellular Biochemistry, 2004, v. 91, n. 5, p. 915, doi. 10.1002/jcb.20008

By:

Aleksandar Francki;
Timothy D. McClure;
Rolf A. Brekken;
Kouros Motamed;
Carrie Murri;
Tongwen Wang;
E. Helene Sage

Publication type:

Article

Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model.

Published in:

International Journal of Cancer, 2007, v. 121, n. 10, p. 2181, doi. 10.1002/ijc.22937

By:

Whitehurst, Brandt;
Flister, Michael J.;
Bagaitkar, Juhi;
Volk, Lisa;
Bivens, Christopher M.;
Pickett, Brent;
Castro-Rivera, Emely;
Brekken, Rolf A.;
Gerard, Robert D.;
Ran, Sophia

Publication type:

Article

The effects of aging on tumor growth and angiogenesis are tumor-cell dependent.

Published in:

International Journal of Cancer, 2007, v. 120, n. 4, p. 753, doi. 10.1002/ijc.22351

By:

Reed, May J.;
Karres, Nathan;
Eyman, Daniel;
Cruz, Abigail;
Brekken, Rolf A.;
Plymate, Stephen

Publication type:

Article

Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02332-3

By:

Chensu Wang;
Niederstrasser, Hanspeter;
Douglas, Peter M.;
Rueyling Lin;
Jaramillo, Juan;
Yang Li;
Oswald, Nathaniel W.;
Anwu Zhou;
McMillan, Elizabeth A.;
Mendiratta, Saurabh;
Zhaohui Wang;
Tian Zhao;
Zhiqaing Lin;
Min Luo;
Gang Huang;
Brekken, Rolf A.;
Posner, Bruce A.;
MacMillan, John B.;
Jinming Gao;
White, Michael A.

Publication type:

Article

Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 16, p. 4467, doi. 10.1128/MCB.00192-09

By:

Halberg, Nils;
Khan, Tayeba;
Trujillo, Maria E.;
Wernstedt-Asterholm, Ingrid;
Attie, Alan D.;
Sherwani, Shariq;
Wang, Zhao V.;
Landskroner-Eiger, Shira;
Dineen, Sean;
Magalang, Ulysses J.;
Brekken, Rolf A.;
Scherer, Philipp E.

Publication type:

Article

Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77373-8

By:

Layeghi-Ghalehsoukhteh, Somayeh;
Pal Choudhuri, Shreoshi;
Ocal, Ozhan;
Zolghadri, Yalda;
Pashkov, Victor;
Niederstrasser, Hanspeter;
Posner, Bruce A.;
Kantheti, Havish S.;
Azevedo-Pouly, Ana C.;
Huang, Huocong;
Girard, Luc;
MacDonald, Raymond J.;
Brekken, Rolf A.;
Wilkie, Thomas M.

Publication type:

Article

Behind the Wheel of Epithelial Plasticity in KRAS-Driven Cancers.

Published in:

Frontiers in Oncology, 2019, p. 1, doi. 10.3389/fonc.2019.01049

By:

Arner, Emily N.;
Du, Wenting;
Brekken, Rolf A.

Publication type:

Article

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

Published in:

Oncogene, 2002, v. 21, n. 46, p. 7011, doi. 10.1038/sj.onc.1205679

By:

Brantley, Dana M.;
Cheng, Nikki;
Thompson, Erin J.;
Qing Lin;
Brekken, Rolf A.;
Thorpe, Philip E.;
Muraoka, Rebecca S.;
Cerretti, Douglas Pat;
Pozzi, Ambra;
Jackson, Dowdy;
Lin, Charles;
Jin Chen

Publication type:

Article

Increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges in SPARC-null mice.

Published in:

Wound Repair & Regeneration, 2001, v. 9, n. 6, p. 522, doi. 10.1046/j.1524-475x.2001.00522.x

By:

BRADSHAW, AMY D.;
REED, MAY J.;
CARBON, JULIET G.;
PINNEY, EMMETT;
BREKKEN, ROLF A.;
SAGE, E. HELENE

Publication type:

Article

Exposed Phosphatidylserine as a Biomarker for Clear Identification of Breast Cancer Brain Metastases in Mouse Models.

Published in:

Cancers, 2024, v. 16, n. 17, p. 3088, doi. 10.3390/cancers16173088

By:

Wang, Lulu;
Zhao, Alan H.;
Arledge, Chad A.;
Xing, Fei;
Chan, Michael D.;
Brekken, Rolf A.;
Habib, Amyn A.;
Zhao, Dawen

Publication type:

Article

CXCL12 in Pancreatic Cancer: Its Function and Potential as a Therapeutic Drug Target.

Published in:

Cancers, 2022, v. 14, n. 1, p. 86, doi. 10.3390/cancers14010086

By:

Malik, Shivani;
Westcott, Jill M.;
Brekken, Rolf A.;
Burrows, Francis J.

Publication type:

Article

The Colorectal Cancer Tumor Microenvironment and Its Impact on Liver and Lung Metastasis.

Published in:

Cancers, 2021, v. 13, n. 24, p. 6206, doi. 10.3390/cancers13246206

By:

Chandra, Raghav;
Karalis, John D.;
Liu, Charles;
Murimwa, Gilbert Z.;
Voth Park, Josiah;
Heid, Christopher A.;
Reznik, Scott I.;
Huang, Emina;
Minna, John D.;
Brekken, Rolf A.

Publication type:

Article

Perspectives on Hypoxia Signaling in Tumor Stroma.

Published in:

Cancers, 2021, v. 13, n. 12, p. 3070, doi. 10.3390/cancers13123070

By:

Zhang, Yuqing;
Coleman, Morgan;
Brekken, Rolf A.

Publication type:

Article

Heme Oxygenase-1 Inhibition Potentiates the Effects of Nab-Paclitaxel-Gemcitabine and Modulates the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma.

Published in:

Cancers, 2021, v. 13, n. 9, p. 2264, doi. 10.3390/cancers13092264

By:

Ahmad, Iman M.;
Dafferner, Alicia J.;
O'Connell, Kelly A.;
Mehla, Kamiya;
Britigan, Bradley E.;
Hollingsworth, Michael A.;
Abdalla, Maher Y.;
Brekken, Rolf A.

Publication type:

Article

Profiling of Adipose and Skeletal Muscle in Human Pancreatic Cancer Cachexia Reveals Distinct Gene Profiles with Convergent Pathways.

Published in:

Cancers, 2021, v. 13, n. 8, p. 1975, doi. 10.3390/cancers13081975

By:

Narasimhan, Ashok;
Zhong, Xiaoling;
Au, Ernie P.;
Ceppa, Eugene P.;
Nakeeb, Atilla;
House, Michael G.;
Zyromski, Nicholas J.;
Schmidt, C. Max;
Schloss, Katheryn N. H.;
Schloss, Daniel E. I.;
Liu, Yunlong;
Jiang, Guanglong;
Hancock, Bradley A.;
Radovich, Milan;
Kays, Joshua K.;
Shahda, Safi;
Couch, Marion E.;
Koniaris, Leonidas G.;
Zimmers, Teresa A.;
Brekken, Rolf A.

Publication type:

Article

Pancreatic Cancer Meets Human Microbiota: Close Encounters of the Third Kind.

Published in:

Cancers, 2021, v. 13, n. 6, p. 1231, doi. 10.3390/cancers13061231

By:

Arsenijevic, Tatjana;
Nicolle, Remy;
Bouchart, Christelle;
D'Haene, Nicky;
Demetter, Pieter;
Puleo, Francesco;
Van Laethem, Jean-Luc;
Brekken, Rolf A.

Publication type:

Article

The Role of VEGF Receptors as Molecular Target in Nuclear Medicine for Cancer Diagnosis and Combination Therapy.

Published in:

Cancers, 2021, v. 13, n. 5, p. 1072, doi. 10.3390/cancers13051072

By:

Masłowska, Katarzyna;
Halik, Paweł Krzysztof;
Tymecka, Dagmara;
Misicka, Aleksandra;
Gniazdowska, Ewa;
Nowak-Sliwinska, Patrycja;
Griffio-en, Arjan W.;
Brekken, Rolf A.

Publication type:

Article