Works by Breda, Laura

Results: 22

Recent trends in the gene therapy of β-thalassemia.

Published in:

Journal of Blood Medicine, 2015, v. 6, p. 69, doi. 10.2147/JBM.S46256

By:

Finotti, Alessia;
Bianchi, Nicoletta;
Zuccato, Cristina;
Gambari, Roberto;
Breda, Laura;
Rivella, Stefano;
Lederer, Carsten W.;
Kleanthous, Marina

Publication type:

Article

Production of β-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous β<sup>0</sup>39 thalassemia patients.

Published in:

American Journal of Hematology, 2009, v. 84, n. 11, p. 720, doi. 10.1002/ajh.21539

By:

Salvatori, Francesca;
Breveglieri, Giulia;
Zuccato, Cristina;
Finotti, Alessia;
Bianchi, Nicoletta;
Borgatti, Monica;
Feriotto, Giordana;
Destro, Federica;
Canella, Alessandro;
Brognara, Eleonora;
Lampronti, Ilaria;
Breda, Laura;
Rivella, Stefano;
Gambari, Roberto

Publication type:

Article

mRNA expression of iron regulatory genes in β‐thalassemia intermedia and β‐thalassemia major mouse models.

Published in:

American Journal of Hematology, 2006, v. 81, n. 7, p. 479, doi. 10.1002/ajh.20549

By:

Orly Weizer‐Stern;
Konstantin Adamsky;
Ninette Amariglio;
Eliezer Rachmilewitz;
Laura Breda;
Stefano Rivella;
Gideon Rechavi

Publication type:

Article

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.

Published in:

2010

By:

Gardenghi, Sara;
Ramos, Pedro;
Marongiu, Maria Franca;
Melchiori, Luca;
Breda, Laura;
Guy, Ella;
Muirhead, Kristen;
Rao, Niva;
Roy, Cindy N.;
Andrews, Nancy C.;
Nemeth, Elizabeta;
Follenzi, Antonia;
Xiuli An;
Mohandas, Narla;
Ginzburg, Yelena;
Rachmilewitz, Eliezer A.;
Giardina, Patricia J.;
Grady, Robert W.;
Rivella, Stefano;
An, Xiuli

Publication type:

journal article

Downregulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera.

Published in:

British Journal of Haematology, 2006, v. 135, n. 1, p. 129, doi. 10.1111/j.1365-2141.2006.06258.x

By:

Weizer-Stern, Orly;
Adamsky, Konstantin;
Amariglio, Ninette;
Levin, Carina;
Koren, Ariel;
Breuer, William;
Rachmilewitz, Eliezer;
Breda, Laura;
Rivella, Stefano;
Ioav Cabantchik, Z.;
Rechavi, Gideon

Publication type:

Article

Decreased hepcidin mRNA expression in thalassemic mice.

Published in:

2004

By:

Adamsky, Konstantin;
Weizer, Orly;
Amariglio, Ninette;
Breda, Laura;
Harmelin, Alon;
Rivella, Stefano;
Rachmilewitz, Eliezer;
Rechavi, Gideon

Publication type:

Letter

Development of K562 cell clones expressing β-globin mRNA carrying the β039 thalassaemia mutation for the screening of correctors of stop-codon mutations.

Published in:

Biotechnology & Applied Biochemistry, 2009, v. 54, n. 1, p. 41, doi. 10.1042/BA20080266

By:

Francesca Salvatori;
Vera Cantale;
Giulia Breveglieri;
Cristina Zuccato;
Alessia Finotti;
Nicoletta Bianchi;
Monica Borgatti;
Giordana Feriotto;
Federica Destro;
Alessandro Canella;
Laura Breda;
Stefano Rivella

Publication type:

Article

Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles.

Published in:

AAPS Journal, 2004, v. 6, n. 1, p. 10, doi. 10.1208/ps060102

By:

Cortesi, Rita;
Mischiati, Carlo;
Borgatti, Monica;
Breda, Laura;
Romanelli, Alessandra;
Saviano, Michele;
Pedone, Carlo;
Gambari, Roberto;
Nastruzzi, Claudio

Publication type:

Article

A validated cellular biobank for β-thalassemia.

Published in:

2016

By:

Cosenza, Lucia Carmela;
Breda, Laura;
Breveglieri, Giulia;
Zuccato, Cristina;
Finotti, Alessia;
Lampronti, Ilaria;
Borgatti, Monica;
Chiavilli, Francesco;
Gamberini, Maria Rita;
Satta, Stefania;
Manunza, Laura;
De Martis, Franca Rosa;
Moi, Paolo;
Rivella, Stefano;
Gambari, Roberto;
Bianchi, Nicoletta

Publication type:

journal article

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity.

Published in:

Journal of Biomedical Science, 2004, v. 11, n. 5, p. 697, doi. 10.1007/BF02256136

By:

Mischiati, Carlo;
Sereni, Alessia;
Finotti, Alessia;
Breda, Laura;
Cortesi, Rita;
Nastruzzi, Claudio;
Romanelli, Alessandra;
Saviano, Michele;
Bianchi, Nicoletta;
Pedone, Carlo;
Borgatti, Monica;
Gambari, Roberto

Publication type:

Article

Gene Therapy for Beta-Hemoglobinopathies: Milestones, New Therapies and Challenges.

Published in:

Molecular Diagnosis & Therapy, 2019, v. 23, n. 2, p. 173, doi. 10.1007/s40291-019-00383-4

By:

Ghiaccio, Valentina;
Chappell, Maxwell;
Rivella, Stefano;
Breda, Laura

Publication type:

Article

A preclinical approach for gene therapy of β-thalassemia.

Published in:

Annals of the New York Academy of Sciences, 2010, v. 1202, n. 1, p. 134, doi. 10.1111/j.1749-6632.2010.05594.x

By:

Breda, Laura;
Kleinert, Dorothy A.;
Casu, Carla;
Casula, Laura;
Cartegni, Luca;
Fibach, Eitan;
Mancini, Irene;
Giardina, Patricia J.;
Gambari, Roberto;
Rivella, Stefano

Publication type:

Article

Exploring the Role of Hepcidin, an Antimicrobial and Iron Regulatory Peptide, in Increased Iron Absorption in β-Thalassemia.

Published in:

Annals of the New York Academy of Sciences, 2005, v. 1054, n. 1, p. 417, doi. 10.1196/annals.1345.069

By:

BREDA, LAURA;
GARDENGHI, SARA;
GUY, ELLA;
RACHMILEWITZ, ELIEZER A.;
WEIZER‐STERN, ORLY;
ADAMSKY, KONSTANTIN;
AMARIGLIO, NINETTE;
RECHAVI, GIDEON;
GIARDINA, PATRICIA J.;
GRADY, ROBERT W.;
RIVELLA, STEFANO

Publication type:

Article

Role of Iron in Inducing Oxidative Stress in Thalassemia: Can It Be Prevented by Inhibition of Absorption and by Antioxidants?

Published in:

Annals of the New York Academy of Sciences, 2005, v. 1054, n. 1, p. 118, doi. 10.1196/annals.1345.014

By:

RACHMILEWITZ, ELIEZER A.;
WEIZER‐STERN, ORLY;
ADAMSKY, KONSTANTIN;
AMARIGLIO, NINETTE;
RECHAVI, GIDEON;
BREDA, LAURA;
RIVELLA, STEFANO;
CABANTCHIK, Z IOAV

Publication type:

Article

Quand l'ubiquitination se mêle du mélanome cutané: Un mécanisme à explorer.

Published in:

Médecine Sciences, 2024, v. 40, n. 3, p. 308, doi. 10.1051/medsci/2024021

By:

Arrighi, Nicole;
Breda, Laura;
Kerdilès, Tiffany;
Meyer, Charlène;
Prugneau, Laura;
Rabatel, Ophélie;
Wagner, Gaëlle;
Krossa, Imène;
Pisibon, Céline

Publication type:

Article

Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia.

Published in:

Nature Medicine, 2013, v. 19, n. 4, p. 437, doi. 10.1038/nm.3126

By:

Ramos, Pedro;
Casu, Carla;
Gardenghi, Sara;
Breda, Laura;
Crielaard, Bart J;
Guy, Ella;
Marongiu, Maria Franca;
Gupta, Ritama;
Levine, Ross L;
Abdel-Wahab, Omar;
Ebert, Benjamin L;
Van Rooijen, Nico;
Ghaffari, Saghi;
Grady, Robert W;
Giardina, Patricia J;
Rivella, Stefano

Publication type:

Article

The challenging diagnosis of cranial congenital anomalies in a newborn from an Italian 20th century documented skeletal collection.

Published in:

International Journal of Osteoarchaeology, 2021, v. 31, n. 2, p. 309, doi. 10.1002/oa.2952

By:

Palamenghi, Andrea;
Biehler‐Gomez, Lucie;
Mattia, Mirko;
Breda, Laura;
Cattaneo, Cristina

Publication type:

Article

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/687635

By:

Breveglieri, Giulia;
Mancini, Irene;
Bianchi, Nicoletta;
Lampronti, Ilaria;
Salvatori, Francesca;
Fabbri, Enrica;
Zuccato, Cristina;
Cosenza, Lucia C.;
Montagner, Giulia;
Borgatti, Monica;
Altruda, Fiorella;
Fagoonee, Sharmila;
Carandina, Gianni;
Rubini, Michele;
Aiello, Vincenzo;
Breda, Laura;
Rivella, Stefano;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

Therapeutic Hemoglobin Levels after Gene Transfer in β-Thalassemia Mice and in Hematopoietic Cells of β-Thalassemia and Sickle Cells Disease Patients.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032345

By:

Breda, Laura;
Casu, Carla;
Gardenghi, Sara;
Bianchi, Nicoletta;
Cartegni, Luca;
Narla, Mohandas;
Yazdanbakhsh, Karina;
Musso, Marco;
Manwani, Deepa;
Little, Jane;
Gardner, Lawrence B.;
Kleinert, Dorothy A.;
Prus, Eugenia;
Fibach, Eitan;
Grady, Robert W.;
Giardina, Patricia J.;
Gambari, Roberto;
Rivella, Stefano

Publication type:

Article

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.

Published in:

Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 29, p. 7669, doi. 10.1007/s00216-019-01959-z

By:

Breveglieri, Giulia;
Salvatori, Francesca;
Finotti, Alessia;
Cosenza, Lucia Carmela;
Zuccato, Cristina;
Bianchi, Nicoletta;
Breda, Laura;
Rivella, Stefano;
Bresciani, Alberto;
Bisbocci, Monica;
Borgatti, Monica;
Gambari, Roberto

Publication type:

Article

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction.

Published in:

2012

By:

Zuccato C;
Breda L;
Salvatori F;
Breveglieri G;
Gardenghi S;
Bianchi N;
Brognara E;
Lampronti I;
Borgatti M;
Rivella S;
Gambari R;
Zuccato, Cristina;
Breda, Laura;
Salvatori, Francesca;
Breveglieri, Giulia;
Gardenghi, Sara;
Bianchi, Nicoletta;
Brognara, Eleonora;
Lampronti, Ilaria;
Borgatti, Monica

Publication type:

journal article

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction.

Published in:

Annals of Hematology, 2012, v. 91, n. 8, p. 1201, doi. 10.1007/s00277-012-1430-5

By:

Zuccato, Cristina;
Breda, Laura;
Salvatori, Francesca;
Breveglieri, Giulia;
Gardenghi, Sara;
Bianchi, Nicoletta;
Brognara, Eleonora;
Lampronti, Ilaria;
Borgatti, Monica;
Rivella, Stefano;
Gambari, Roberto

Publication type:

Article