Works matching AU Brazzolotto, Xavier

Results: 32

Front Cover: Detoxification of V‐Nerve Agents Assisted by a Microperoxidase: New Pathway Revealed by the Use of a Relevant VX Simulant (ChemBioChem 15/2024).

Published in:

ChemBioChem, 2024, v. 25, n. 15, p. 1, doi. 10.1002/cbic.202481501

By:

da Silva, Valmir Baptista;
Mahy, Jean‐Pierre;
Brazzolotto, Xavier;
Renard, Pierre‐Yves;
Ricoux, Rémy;
Legros, Julien

Publication type:

Article

Detoxification of V‐Nerve Agents Assisted by a Microperoxidase: New Pathway Revealed by the Use of a Relevant VX Simulant.

Published in:

ChemBioChem, 2024, v. 25, n. 15, p. 1, doi. 10.1002/cbic.202400137

By:

da Silva, Valmir Baptista;
Mahy, Jean‐Pierre;
Brazzolotto, Xavier;
Renard, Pierre‐Yves;
Ricoux, Rémy;
Legros, Julien

Publication type:

Article

Grid‐Type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions.

Published in:

ChemBioChem, 2022, v. 23, n. 23, p. 1, doi. 10.1002/cbic.202200456

By:

Nachon, Florian;
Brazzolotto, Xavier;
Dias, José;
Courageux, Charlotte;
Drożdż, Wojciech;
Cao, Xiao‐Yu;
Stefankiewicz, Artur R.;
Lehn, Jean‐Marie

Publication type:

Article

Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model.

Published in:

Communications Chemistry, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42004-019-0133-4

By:

Dighe, Satish N.;
De la Mora, Eugenio;
Chan, Stephen;
Kantham, Srinivas;
McColl, Gawain;
Miles, Jared A.;
Veliyath, Suresh Kumar;
Sreenivas, B. Yogi;
Nassar, Zeyad D.;
Silman, Israel;
Sussman, Joel L.;
Weik, Martin;
McGeary, Ross P.;
Parat, Marie-Odile;
Brazzolotto, Xavier;
Ross, Benjamin P.

Publication type:

Article

Role of paraoxonase 1 in organophosphate G-series nerve agent poisoning and future therapeutic strategies.

Published in:

2025

By:

Tripathy, Rajan K.;
Khandave, Prakash Y.;
Bzdrenga, Janek;
Nachon, Florian;
Brazzolotto, Xavier;
Pande, Abhay H.

Publication type:

Literature Review

Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure.

Published in:

FEBS Journal, 2012, v. 279, n. 16, p. 2905, doi. 10.1111/j.1742-4658.2012.08672.x

By:

Brazzolotto, Xavier;
Wandhammer, Marielle;
Ronco, Cyril;
Trovaslet, Marie;
Jean, Ludovic;
Lockridge, Oksana;
Renard, Pierre-Yves;
Nachon, Florian

Publication type:

Article

Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 498, doi. 10.1080/14756366.2019.1710502

By:

Pajk, Stane;
Knez, Damijan;
Košak, Urban;
Zorović, Maja;
Brazzolotto, Xavier;
Coquelle, Nicolas;
Nachon, Florian;
Colletier, Jacques-Philippe;
Živin, Marko;
Stojan, Jure;
Gobec, Stanislav

Publication type:

Article

Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 9, p. 687, doi. 10.1107/S2053230X16011778

By:

Contesto-Richefeu, Céline;
Tarbouriech, Nicolas;
Brazzolotto, Xavier;
Burmeister, Wim P.;
Peyrefitte, Christophe N.;
Iseni, Frédéric

Publication type:

Article

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Published in:

Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202420510

By:

Panek, Dawid;
Pasieka, Anna;
Jończyk, Jakub;
Gawlińska, Milena;
Zaręba, Paula;
Siwek, Agata;
Wolak, Małgorzata;
Mordyl, Barbara;
Głuch‐Lutwin, Monika;
Latacz, Gniewomir;
Brazzolotto, Xavier;
Chantegreil, Fabien;
Nachon, Florian;
Zdarova Karasova, Jana;
Pejchal, Jaroslav;
Mzik, Martin;
Sestak, Vit;
Prchal, Lukas;
Odvarkova, Jitka;
Soukup, Ondrej

Publication type:

Article

Biochemical characterization of the HydE and HydG iron-only hydrogenase maturation enzymes from Thermatoga maritima

Published in:

FEBS Letters, 2005, v. 579, n. 22, p. 5055, doi. 10.1016/j.febslet.2005.07.092

By:

Rubach, Jon K.;
Brazzolotto, Xavier;
Gaillard, Jacques;
Fontecave, Marc

Publication type:

Article

Crystal Structure of the Vaccinia Virus DNA Polymerase Holoenzyme Subunit D4 in Complex with the A20 N-Terminal Domain.

Published in:

PLoS Pathogens, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.ppat.1003978

By:

Contesto-Richefeu, Céline;
Tarbouriech, Nicolas;
Brazzolotto, Xavier;
Betzi, Stéphane;
Morelli, Xavier;
Burmeister, Wim P.;
Iseni, Frédéric

Publication type:

Article

Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime.

Published in:

Biomolecules (2218-273X), 2020, v. 10, n. 6, p. 858, doi. 10.3390/biom10060858

By:

Calas, André-Guilhem;
Hanak, Anne-Sophie;
Jaffré, Nina;
Nervo, Aurélie;
Dias, José;
Rousseau, Catherine;
Courageux, Charlotte;
Brazzolotto, Xavier;
Villa, Pascal;
Obrecht, Adeline;
Goossens, Jean-François;
Landry, Christophe;
Hachani, Johan;
Gosselet, Fabien;
Dehouck, Marie-Pierre;
Yerri, Jagadeesh;
Kliachyna, Maria;
Baati, Rachid;
Nachon, Florian

Publication type:

Article

Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases.

Published in:

Antioxidants, 2021, v. 10, n. 2, p. 329, doi. 10.3390/antiox10020329

By:

Chavarria, Daniel;
Da Silva, Ophelie;
Benfeito, Sofia;
Barreiro, Sandra;
Garrido, Jorge;
Cagide, Fernando;
Soares, Pedro;
Remião, Fernando;
Brazzolotto, Xavier;
Nachon, Florian;
Oliveira, Paulo J.;
Dias, José;
Borges, Fernanda;
Saso, Luciano;
Amarowicz, Ryszard;
Marković, Jasmina Dimitrić

Publication type:

Article

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostastis.

Published in:

EMBO Journal, 2004, v. 23, n. 2, p. 386, doi. 10.1038/sj.emboj.7600041

By:

Meyron-Holtz, Esther G.;
Ghosh, Manik C.;
Iwai, Kazuhiro;
LaVaute, Timothy;
Brazzolotto, Xavier;
Berger, Urs V.;
Land, William;
Ollivierre-Wilson, Hayden;
Grinberg, Alex;
Love, Paul;
Rouault, Tracey A.

Publication type:

Article

Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases.

Published in:

Biochemical Journal, 2020, v. 477, n. 15, p. 2771, doi. 10.1042/BCJ20200192

By:

Marakovic, Nikola;
Kneževic, Anamarija;
Roncevic, Igor;
Brazzolotto, Xavier;
Kovarik, Zrinka

Publication type:

Article

Three conserved histidine residues contribute to mitochondrial iron transport through mitoferrins.

Published in:

Biochemical Journal, 2014, v. 460, n. 1, p. 79, doi. 10.1042/BJ20140107

By:

BRAZZOLOTTO, Xavier;
PIERREL, Fabien;
PELOS, Ludovic

Publication type:

Article

BUTYRYLCHOLINESTERASE INHIBITORS GRAFTED WITH ANTIOXIDANT AND NEUROPROTECTIVE ACTIVITIES: NOVEL MULTIFUNCTIONAL LIGANDS FOR ALZHEIMER'S DISEASE.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 127

By:

Knez, Damijan;
Coquelle, Nicolas;
Pišlar, Anja;
Žakelj, Simon;
Jukič, Marko;
Sova, Matej;
Mravljak, Janez;
Nachon, Florian;
Brazzolotto, Xavier;
Kos, Janko;
Colletier, Jacques-Philippe;
Gobec, Stanislav

Publication type:

Article

EVOLUTION OF THE FIRST DISULFIDE BOND IN THE CHOLINESTERASE- CARBOXYLESTERASE (COESTERASE) FAMILY: POSSIBLE CONSEQUENCES FOR CHOLINESTERASE EXPRESSION IN PROKARYOTES.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 55

By:

Chatonnet, Arnaud;
Brazzolotto, Xavier;
Hotelier, Thierry;
Lenfant, Nicolas;
Marchot, Pascale

Publication type:

Article

CRYSTAL STRUCTURES OF HUMAN CHOLINESTERASES IN COMPLEX WITH SUPRAMOLECULAR LIGANDS.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 50

By:

Dias, José;
Brazzolotto, Xavier;
Xiao-Yu Cao;
Stefankiewicz, Artur;
Lehn, Jean-Marie;
Nachon, Florian

Publication type:

Article

PROKARYOTIC EXPRESSION OF HUMAN BUTYRYLCHOLINESTERASE AS A TOOL FOR CATALYTIC BIOSCAVENGER DEVELOPMENT.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 37

By:

Brazzolotto, Xavier;
Igert, Alexandre;
Guillon, Virginia;
Santoni, Gianluca;
Nachon, Florian

Publication type:

Article

RECIPES TO DESIGN SPECIFIC LIGANDS OF HUMAN BUTYRYLCHOLINESTERASE.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 8

By:

Nachon, Florian;
Colletier, Jacques-Philippe;
Coquelle, Nicolas;
Brazzolotto, Xavier

Publication type:

Article

Detoxification of Chemical Warfare Agents by a Zr‐Based MOF with High Recycling Ability at Physiological pH.

Published in:

ChemNanoMat, 2024, v. 10, n. 8, p. 1, doi. 10.1002/cnma.202400132

By:

Biswas, Subharanjan;
Gay, Rémy;
Bzdrenga, Janek;
Soirot, Thomas;
Belverge, Nicolas;
Taudon, Nicolas;
Brazzolotto, Xavier;
Haouas, Mohamed;
Steunou, Nathalie;
Mahy, Jean‐Pierre;
Ricoux, Rémy

Publication type:

Article

Front Cover: Inhibition of Human Cholinesterases and in vitro β‐Amyloid Aggregation by Rationally Designed Peptides (ChemMedChem 12/2023).

Published in:

ChemMedChem, 2023, v. 18, n. 12, p. 1, doi. 10.1002/cmdc.202300289

By:

Sanchis, Ivan;
Spinelli, Roque;
Dias, José;
Brazzolotto, Xavier;
Rietmann, Álvaro;
Aimaretti, Florencia;
Siano, Álvaro S.

Publication type:

Article

Inhibition of Human Cholinesterases and in vitro β‐Amyloid Aggregation by Rationally Designed Peptides.

Published in:

ChemMedChem, 2023, v. 18, n. 12, p. 1, doi. 10.1002/cmdc.202200691

By:

Sanchis, Ivan;
Spinelli, Roque;
Dias, José;
Brazzolotto, Xavier;
Rietmann, Álvaro;
Aimaretti, Florencia;
Siano, Álvaro S.

Publication type:

Article

An EPR/HYSCORE, Mössbauer, and resonance Raman study of the hydrogenase maturation enzyme HydF: a model for N-coordination to [4Fe-4S] clusters.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2014, v. 19, n. 1, p. 75, doi. 10.1007/s00775-013-1062-9

By:

Berggren, Gustav;
Garcia-Serres, Ricardo;
Brazzolotto, Xavier;
Clemancey, Martin;
Gambarelli, Serge;
Atta, Mohamed;
Latour, Jean-Marc;
Hernández, Heather;
Subramanian, Sowmya;
Johnson, Michael;
Fontecave, Marc

Publication type:

Article

A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study.

Published in:

Molecules, 2021, v. 26, n. 3, p. 657, doi. 10.3390/molecules26030657

By:

Bzdrenga, Janek;
Trenet, Elodie;
Chantegreil, Fabien;
Bernal, Kevin;
Nachon, Florian;
Brazzolotto, Xavier;
Afarinkia, Kamyar;
Chemat, Farid

Publication type:

Article

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study.

Published in:

Molecules, 2017, v. 22, n. 12, p. 2098, doi. 10.3390/molecules22122098

By:

Rosenberry, Terrone L.;
Brazzolotto, Xavier;
Macdonald, Ian R.;
Wandhammer, Marielle;
Trovaslet-Leroy, Marie;
Darvesh, Sultan;
Nachon, Florian

Publication type:

Article

Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development.

Published in:

Molecules, 2017, v. 22, n. 11, p. 1828, doi. 10.3390/molecules22111828

By:

Brazzolotto, Xavier;
Igert, Alexandre;
Guillon, Virginia;
Santoni, Gianluca;
Nachon, Florian

Publication type:

Article

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

Published in:

Scientific Reports, 2016, p. 39495, doi. 10.1038/srep39495

By:

Košak, Urban;
Brus, Boris;
Knez, Damijan;
Šink, Roman;
Žakelj, Simon;
Trontelj, Jurij;
Pišlar, Anja;
Šlenc, Jasna;
Gobec, Martina;
Živin, Marko;
Tratnjek, Larisa;
Perše, Martina;
Sałat, Kinga;
Podkowa, Adrian;
Filipek, Barbara;
Nachon, Florian;
Brazzolotto, Xavier;
Więckowska, Anna;
Malawska, Barbara;
Stojan, Jure

Publication type:

Article

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 6, p. 1, doi. 10.1002/anie.202420510

By:

Panek, Dawid;
Pasieka, Anna;
Jończyk, Jakub;
Gawlińska, Milena;
Zaręba, Paula;
Siwek, Agata;
Wolak, Małgorzata;
Mordyl, Barbara;
Głuch‐Lutwin, Monika;
Latacz, Gniewomir;
Brazzolotto, Xavier;
Chantegreil, Fabien;
Nachon, Florian;
Zdarova Karasova, Jana;
Pejchal, Jaroslav;
Mzik, Martin;
Sestak, Vit;
Prchal, Lukas;
Odvarkova, Jitka;
Soukup, Ondrej

Publication type:

Article

Discovery of drug‐like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database.

Published in:

Chemical Biology & Drug Design, 2021, v. 97, n. 5, p. 1048, doi. 10.1111/cbdd.13825

By:

Miles, Jared A.;
Ng, Jia Hui;
Sreenivas, B. Yogi;
Courageux, Charlotte;
Igert, Alexandre;
Dias, José;
McGeary, Ross P.;
Brazzolotto, Xavier;
Ross, Benjamin P.

Publication type:

Article

Cover Image.

Published in:

Chemical Biology & Drug Design, 2021, v. 97, n. 5, p. i, doi. 10.1111/cbdd.13717

By:

Miles, Jared A.;
Ng, Jia Hui;
Sreenivas, B. Yogi;
Courageux, Charlotte;
Igert, Alexandre;
Dias, José;
McGeary, Ross P.;
Brazzolotto, Xavier;
Ross, Benjamin P.

Publication type:

Article