Found: 14
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Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response.
- Published in:
- Aging Cell, 2024, v. 23, n. 5, p. 1, doi. 10.1111/acel.14126
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- Article
DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice.
- Published in:
- Aging Cell, 2023, v. 22, n. 3, p. 1, doi. 10.1111/acel.13768
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- Publication type:
- Article
Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health.
- Published in:
- Frontiers in Aging Neuroscience, 2023, v. 15, p. 1, doi. 10.3389/fnagi.2022.1095801
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- Article
The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
- Published in:
- Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.1005322
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- Article
Soluble guanylate cyclase activator BAY 54–6544 improves vasomotor function and survival in an accelerated ageing mouse model.
- Published in:
- Aging Cell, 2022, v. 21, n. 9, p. 1, doi. 10.1111/acel.13683
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- Publication type:
- Article
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice.
- Published in:
- Aging Cell, 2021, v. 20, n. 2, p. 1, doi. 10.1111/acel.13302
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- Publication type:
- Article
DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-12640-5
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- Article
Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1<sup>−/Δ7</sup> mice.
- Published in:
- Immunity & Ageing, 2019, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12979-019-0145-z
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- Article
Frontline Science: Tryptophan restriction arrests B cell development and enhances microbial diversity in WT and prematurely aging Ercc1<sup>−/Δ7</sup> mice.
- Published in:
- Journal of Leukocyte Biology, 2017, v. 101, n. 4, p. 811, doi. 10.1189/jlb.1HI0216-062RR
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- Article
Cockayne Syndrome Group B (Csb) and Group A (Csa) Deficiencies Predispose to Hearing Loss and Cochlear Hair Cell Degeneration in Mice.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 10, p. 4280, doi. 10.1523/JNEUROSCI.5063-14.2015
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- Article
Cell-Autonomous Progeroid Changes in Conditional Mouse Models for Repair Endonuclease XPG Deficiency.
- Published in:
- PLoS Genetics, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.pgen.1004686
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- Publication type:
- Article
Age-Related Skeletal Dynamics and Decrease in Bone Strength in DNA Repair Deficient Male Trichothiodystrophy Mice.
- Published in:
- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035246
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- Article
Correction: Impaired Genome Maintenance Suppresses the Growth HormoneInsulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome.
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- 2008
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- Correction notice
Impaired Genome Maintenance Suppresses the Growth Hormone--Insulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome.
- Published in:
- PLoS Biology, 2007, v. 5, n. 1, p. 23, doi. 10.1371/journal.pbio.0050002
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- Publication type:
- Article