Works by Braithwaite, Antony

Results: 43

Effect of p53 and its N‐terminally truncated isoform, Δ40p53, on breast cancer migration and invasion.

Published in:

Molecular Oncology, 2022, v. 16, n. 2, p. 447, doi. 10.1002/1878-0261.13118

By:

Zhang, Xiajie;
Groen, Kira;
Morten, Brianna C.;
Steffens Reinhardt, Luiza;
Campbell, Hamish G.;
Braithwaite, Antony W.;
Bourdon, Jean‐Christophe;
Avery‐Kiejda, Kelly A.

Publication type:

Article

Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25550-2

By:

Arsic, Nikola;
Slatter, Tania;
Gadea, Gilles;
Villain, Etienne;
Fournet, Aurelie;
Kazantseva, Marina;
Allemand, Frédéric;
Sibille, Nathalie;
Seveno, Martial;
de Rossi, Sylvain;
Mehta, Sunali;
Urbach, Serge;
Bourdon, Jean-Christophe;
Bernado, Pau;
Kajava, Andrey V.;
Braithwaite, Antony;
Roux, Pierre

Publication type:

Article

The deleted in colorectal carcinoma (DCC) gene 201 R ? G polymorphism: no evidence for genetic association with autoimmune disease.

Published in:

European Journal of Human Genetics, 2003, v. 11, n. 11, p. 840, doi. 10.1038/sj.ejhg.5201059

By:

Hall, Richard J.;
Merriman, Marilyn E.;
Green, Rachel A.;
Markham, Valerie H.;
Smyth, Deborah J.;
Heward, Joanne M.;
Jennings, Claire E.;
Braithwaite, Antony W.;
Cundy, Tim;
Darlow, Brian A.;
Gow, Peter J.;
Harrison, Andrew A.;
Highton, John;
Hunt, Penny J.;
Manning, Patrick;
Pokorny, Violetta;
Scott, Russell S.;
Taylor, Barry J.;
Willis, Jinny A.;
Yeoman, Sue

Publication type:

Article

Immune Checkpoint Inhibitor Therapy for Metastatic Melanoma: What Should We Focus on to Improve the Clinical Outcomes?

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 18, p. 10120, doi. 10.3390/ijms251810120

By:

Hossain, Sultana Mehbuba;
Ly, Kevin;
Sung, Yih Jian;
Braithwaite, Antony;
Li, Kunyu

Publication type:

Article

Increased Expression of the Δ133p53β Isoform Enhances Brain Metastasis.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 1267, doi. 10.3390/ijms24021267

By:

Jesus, Alexandra N. Boix De;
Taha, Ahmad;
Wang, David;
Mehta, Paulomi M.;
Mehta, Sunali;
Reily-Bell, Ashley;
Lekamlage, Sasini Polwatta;
Saraiva, Adriana Machado;
Tahmeedzaman, Tahmeed;
Ziad, Fouzia;
Thotathil, Ziad;
Gan, Peter Y. C.;
Royds, Janice;
Braithwaite, Antony;
Hung, Noelyn;
Slatter, Tania L.

Publication type:

Article

Mouse p53 inhibits SV40 origin-dependent DNA replication.

Published in:

Nature, 1987, v. 329, n. 6138, p. 458, doi. 10.1038/329458a0

By:

Braithwaite, Antony W.;
Sturzbecher, Horst-Werner;
Addison, Christine;
Palmer, Colin;
Rudge, Karran;
Jenkins, John R.

Publication type:

Article

Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.

Published in:

Journal of Cell Biology, 2009, v. 185, n. 5, p. 797, doi. 10.1083/jcb.200810084

By:

Wei-Qin Jiang;
Ze-Huai Zhong;
Nguyen, Akira;
Henson, Jeremy D.;
Toouli, Christian D.;
Reddel, Roger R.;
Braithwaite, Antony W.

Publication type:

Article

Importance of crosstalk between the microbiota and the neuroimmune system for tissue homeostasis.

Published in:

Clinical & Translational Immunology, 2022, v. 11, n. 5, p. 1, doi. 10.1002/cti2.1394

By:

Li, Kunyu;
Ly, Kevin;
Mehta, Sunali;
Braithwaite, Antony

Publication type:

Article

Cohesin mutations are synthetic lethal with stimulation of WNT signaling.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.61405

By:

Chue Vin Chin;
Antony, Jisha;
Ketharnathan, Sarada;
Labudina, Anastasia;
Gimenez, Gregory;
Parsons, Kate M.;
Jinshu He;
George, Amee J.;
Pallotta, Maria Michela;
Musio, Antonio;
Braithwaite, Antony;
Guilford, Parry;
Hannan, Ross D.;
Horsfield, Julia A.

Publication type:

Article

Antitumor cytotoxicity induced by bone-marrow-derived antigen-presenting cells is facilitated by the tumor suppressor protein p53 via regulation of IL-12.

Published in:

OncoImmunology, 2016, v. 5, n. 3, p. 1, doi. 10.1080/2162402X.2015.1112941

By:

Slatter, Tania L.;
Wilson, Michelle;
Tang, Chingwen;
Campbell, Hamish G.;
Ward, Vernon K.;
Young, Vivienne L.;
Van Ly, David;
Fleming, Nicholas I.;
Braithwaite, Antony W.;
Baird, Margaret A.

Publication type:

Article

Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression.

Published in:

Molecular Cancer, 2011, v. 10, n. 1, p. 78, doi. 10.1186/1476-4598-10-78

By:

Joshi, Sanket;
Braithwaite, Antony W.;
Robinson, Phillip J.;
Chircop, Megan

Publication type:

Article

Accessing a New Dimension in TP53 Biology: Multiplex Long Amplicon Digital PCR to Specifically Detect and Quantitate Individual TP53 Transcripts.

Published in:

Cancers, 2020, v. 12, n. 3, p. 769, doi. 10.3390/cancers12030769

By:

Lasham, Annette;
Tsai, Peter;
Fitzgerald, Sandra J.;
Mehta, Sunali Y.;
Knowlton, Nicholas S.;
Braithwaite, Antony W.;
Print, Cristin G.

Publication type:

Article

Dephosphorylation of YB-1 is Required for Nuclear Localisation During G2 Phase of the Cell Cycle.

Published in:

Cancers, 2020, v. 12, n. 2, p. 315, doi. 10.3390/cancers12020315

By:

Mehta, Sunali;
McKinney, Cushla;
Algie, Michael;
Verma, Chandra S.;
Kannan, Srinivasaraghavan;
Harfoot, Rhodri;
Bartolec, Tara K.;
Bhatia, Puja;
Fisher, Alistair J.;
Gould, Maree L.;
Parker, Kim;
Cesare, Anthony J.;
Cunliffe, Heather E.;
Cohen, Scott B.;
Kleffmann, Torsten;
Braithwaite, Antony W.;
Woolley, Adele G.

Publication type:

Article

Does Δ133p53 isoform trigger inflammation and autoimmunity?

Published in:

Cell Cycle, 2012, v. 11, n. 3, p. 446, doi. 10.4161/cc.11.3.19054

By:

Campbell, Hamish G.;
Slatter, Tania L.;
Jeffs, Aaron;
Mehta, Reena;
Rubio, Carina;
Baird, Margaret;
Braithwaite, Antony W.

Publication type:

Article

A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by low cytometry.

Published in:

Cell Cycle, 2010, v. 9, n. 17, p. 3584, doi. 10.4161/cc.9.17.12831

By:

Heinlein, Christina;
Deppert, Wolfgang;
Braithwaite, Antony W.;
Speidel, Daniel

Publication type:

Article

p53-dependent cell death/apoptosis is required for a productive adenovirus infection.

Published in:

Nature Medicine, 1998, v. 4, n. 9, p. 1068, doi. 10.1038/2057

By:

Hall, Anthony R.;
Dix, Brett R.;
O'Carroll, Simon J.;
Braithwaite, Antony W.

Publication type:

Article

A novel EGR-1 dependent mechanism for YB-1 modulation of paclitaxel response in a triple negative breast cancer cell line.

Published in:

International Journal of Cancer, 2016, v. 139, n. 5, p. 1157, doi. 10.1002/ijc.30137

By:

Lasham, Annette;
Mehta, Sunali Y.;
Fitzgerald, Sandra J.;
Woolley, Adele G.;
Hearn, James I.;
Hurley, Daniel G.;
Ruza, Igor;
Algie, Michael;
Shelling, Andrew N.;
Braithwaite, Antony W.;
Print, Cristin G.

Publication type:

Article

Telomere length and periodontal attachment loss: a prospective cohort study.

Published in:

Journal of Clinical Periodontology, 2016, v. 43, n. 2, p. 121, doi. 10.1111/jcpe.12499

By:

Thomson, William Murray;
Zeng, Jiaxu;
Broadbent, Jonathan M.;
Foster Page, Lyndie A.;
Shalev, Idan;
Moffitt, Terrie E.;
Caspi, Avshalom;
Williams, Sheila M.;
Braithwaite, Antony W.;
Robertson, Stephen P.;
Poulton, Richie

Publication type:

Article

Accelerated decline in lung function in cigarette smokers is associated with TP53/MDM2 polymorphisms.

Published in:

Human Genetics, 2009, v. 126, n. 4, p. 559, doi. 10.1007/s00439-009-0704-z

By:

Hancox, Robert J.;
Poulton, Richie;
Welch, David;
Olova, Nelly;
McLachlan, Christene R.;
Greene, Justina M.;
Sears, Malcolm R.;
Caspi, Avshalom;
Moffitt, Terrie E.;
Robertson, Stephen P.;
Braithwaite, Antony W.

Publication type:

Article

The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.

Published in:

Oncogene, 2003, v. 22, n. 29, p. 4517, doi. 10.1038/sj.onc.1206726

By:

Edwards, Sara J;
Hananeia, Lynne;
Eccles, Michael R;
Zhang, You Fang;
Braithwaite, Antony W

Publication type:

Article

Nuclear localization of Y-box factor YB1 requires wild-type p53.

Published in:

Oncogene, 2003, v. 22, n. 18, p. 2782, doi. 10.1038/sj.onc.1206357

By:

Zhang, You Fang;
Homer, Craig;
Edwards, Sara J;
Hananeia, Lynne;
Lasham, Annette;
Royds, Janice;
Sheard, Philip;
Braithwaite, Antony W

Publication type:

Article

Breast Cancer Patient Prognosis Is Determined by the Interplay between TP53 Mutation and Alternative Transcript Expression: Insights from TP53 Long Amplicon Digital PCR Assays.

Published in:

Cancers, 2021, v. 13, n. 7, p. 1531, doi. 10.3390/cancers13071531

By:

Lasham, Annette;
Knowlton, Nicholas;
Mehta, Sunali Y.;
Braithwaite, Antony W.;
Print, Cristin G.;
Bourdon, Jean-Christophe;
Slade, Neda

Publication type:

Article

Heterogeneous gene expression changes in colorectal cancer cells share the WNT pathway in response to growth suppression by APHSmediated COX-2 inhibition.

Published in:

Biologics: Targets & Therapy, 2008, v. 2, n. 2, p. 329

By:

Humar, Bostjan;
McNoe, Les;
Dunbier, Anita;
Heathcott, Rosemary;
Braithwaite, Antony W.;
Reeve, Anthony E.

Publication type:

Article

Increased paired box transcription factor 8 has a survival function in Glioma.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-159

By:

Hung, Noelyn;
Yu-Jen Chen;
Taha, Ahmad;
Olivecrona, Magnus;
Boet, Ronald;
Wiles, Anna;
Warr, Tracy;
Shaw, Alisha;
Eiholzer, Ramona;
Baguley, Bruce C.;
Eccles, Michael R.;
Braithwaite, Antony W.;
MacFarlane, Martin;
Royds, Janice A.;
Slatter, Tania

Publication type:

Article

Increased paired box transcription factor 8 has a survival function in Glioma.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-159

By:

Hung, Noelyn;
Yu-Jen Chen;
Taha, Ahmad;
Olivecrona, Magnus;
Boet, Ronald;
Wiles, Anna;
Warr, Tracy;
Shaw, Alisha;
Eiholzer, l. Ramona;
Baguley, Bruce C.;
Eccles, Michael R.;
Braithwaite, Antony W.;
MacFarlane, Martin;
Royds, Janice A.;
Slatter, Tania

Publication type:

Article

Increased paired box transcription factor 8 has a survival function in glioma.

Published in:

2014

By:

Hung, Noelyn;
Chen, Yu-Jen;
Taha, Ahmad;
Olivecrona, Magnus;
Boet, Ronald;
Wiles, Anna;
Warr, Tracy;
Shaw, Alisha;
Eiholzer, Ramona;
Baguley, Bruce C;
Eccles, Michael R;
Braithwaite, Antony W;
Macfarlane, Martin;
Royds, Janice A;
Slatter, Tania

Publication type:

journal article

YB-1: oncoprotein, prognostic marker and therapeutic target?

Published in:

Biochemical Journal, 2013, v. 449, n. 1, p. 11, doi. 10.1042/BJ20121323

By:

LASHAM, Annette;
PRINT, Cristin G.;
WOOLLEY, Adele G.;
DUNN, Sandra E.;
BRAITHWAITE, Antony W.

Publication type:

Article

Silencing of Testin expression is a frequent event in spontaneous lymphomas from Trp53-mutant mice.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73229-3

By:

Weeks, Robert J.;
Ludgate, Jackie L.;
Le Mée, Gwenn;
Khanal, Rubina;
Mehta, Sunali;
Williams, Gail;
Slatter, Tania L.;
Braithwaite, Antony W.;
Morison, Ian M.

Publication type:

Article

Alpha-Enolase Is Upregulated on the Cell Surface and Responds to Plasminogen Activation in Mice Expressing a ∆133p53α Mimic.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0116270

By:

Sawhney, Sonal;
Hood, Kylie;
Shaw, Alisha;
Braithwaite, Antony W.;
Stubbs, Richard;
Hung, Noelyn A.;
Royds, Janice A.;
Slatter, Tania L.

Publication type:

Article

The CDKN2A G500 Allele Is More Frequent in GBM Patients with No Defined Telomere Maintenance Mechanism Tumors and Is Associated with Poorer Survival.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026737

By:

Royds, Janice A.;
Al Nadaf, Shafagh;
Wiles, Anna K.;
Chen, Yu-Jen;
Ahn, Antonio;
Shaw, Alisha;
Bowie, Sara;
Lam, Frederic;
Baguley, Bruce C.;
Braithwaite, Antony W.;
MacFarlane, Martin R.;
Hung, Noelyn A.;
Slatter, Tania L.

Publication type:

Article

Prognostic Association of YB-1 Expression in Breast Cancers: A Matter of Antibody.

Published in:

PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0020603

By:

Woolley, Adele G.;
Algie, Michael;
Samuel, Weini;
Harfoot, Rhodri;
Wiles, Anna;
Hung, Noelyn A.;
Tan, Puay-Hoon;
Hains, Peter;
Valova, Valentina A.;
Huschtscha, Lily;
Royds, Janice A.;
Perez, David;
Yoon, Han-Seung;
Cohen, Scott B.;
Robinson, Phillip J.;
Bay, Boon-Huat;
Lasham, Annette;
Braithwaite, Antony W.

Publication type:

Article

Altered cell cycle progression and aberrant mitosis in adenovirus-infected rodent cells.

Published in:

Journal of Cellular Physiology, 1982, v. 111, n. 1, p. 89, doi. 10.1002/jcp.1041110114

By:

Murray, James D.;
Bellett, Alan J. D.;
Braithwaite, Antony W.;
Waldron, Lydia K.;
Taylor, Ian W.

Publication type:

Article

YB-1, the E2F Pathway, and Regulation of Tumor Cell Growth.

Published in:

JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 2, p. 133, doi. 10.1093/jnci/djr512

By:

Lasham, Annette;
Samuel, Weini;
Cao, Helen;
Patel, Rachna;
Mehta, Reena;
Stern, J. Lewis;
Reid, Glen;
Woolley, Adele G.;
Miller, Lance D.;
Black, Michael A;
Shelling, Andrew N.;
Print, Cristin G.;
Braithwaite, Antony W.

Publication type:

Article

The p53 story: layers of complexity.

Published in:

Carcinogenesis, 2005, v. 26, n. 7, p. 1161, doi. 10.1093/carcin/bgi091

By:

Antony W. Braithwaite;
Paul Jackson

Publication type:

Article

Activated CD90/Thy-1 fibroblasts co-express the Δ133p53β isoform and are associated with highly inflamed rheumatoid arthritis.

Published in:

Arthritis Research & Therapy, 2023, v. 25, n. 1, p. 1, doi. 10.1186/s13075-023-03040-8

By:

Wiles, Anna K.;
Mehta, Sunali;
Millier, Melanie;
Woolley, Adele G.;
Li, Kunyu;
Parker, Kim;
Kazantseva, Marina;
Wilson, Michelle;
Young, Katie;
Bowie, Sarah;
Ray, Sankalita;
Slatter, Tania L.;
Stamp, Lisa K.;
Hessian, Paul A.;
Braithwaite, Antony W.

Publication type:

Article

Activated CD90/Thy-1 fibroblasts co-express the Δ133p53β isoform and are associated with highly inflamed rheumatoid arthritis.

Published in:

Arthritis Research & Therapy, 2023, v. 25, n. 1, p. 1, doi. 10.1186/s13075-023-03040-8

By:

Wiles, Anna K.;
Mehta, Sunali;
Millier, Melanie;
Woolley, Adele G.;
Li, Kunyu;
Parker, Kim;
Kazantseva, Marina;
Wilson, Michelle;
Young, Katie;
Bowie, Sarah;
Ray, Sankalita;
Slatter, Tania L.;
Stamp, Lisa K.;
Hessian, Paul A.;
Braithwaite, Antony W.

Publication type:

Article

A mouse model of the Δ133p53 isoform: roles in cancer progression and inflammation.

Published in:

Mammalian Genome, 2018, v. 29, n. 11/12, p. 831, doi. 10.1007/s00335-018-9758-3

By:

Kazantseva, Marina;
Mehta, Sunali;
Eiholzer, Ramona A.;
Hung, Noelyn;
Wiles, Anna;
Slatter, Tania L.;
Braithwaite, Antony W.

Publication type:

Article

Adaptive homeostasis and the p53 isoform network.

Published in:

EMBO Reports, 2021, v. 22, n. 12, p. 1, doi. 10.15252/embr.202153085

By:

Mehta, Sunali;
Campbell, Hamish;
Drummond, Catherine J;
Li, Kunyu;
Murray, Kaisha;
Slatter, Tania;
Bourdon, Jean‐Christophe;
Braithwaite, Antony W

Publication type:

Article

Down-regulation of E1a expression by E3 gene products in group C adenoviruses.

Published in:

Immunology & Cell Biology, 1992, v. 70, n. 1, p. 65, doi. 10.1038/icb.1992.10

By:

Xiaoliu Zhang;
Arno Müllbacher;
Braithwaite, Antony W.

Publication type:

Article

Y-box factor YB1 controls p53 apoptotic function.

Published in:

Oncogene, 2005, v. 24, n. 56, p. 8314, doi. 10.1038/sj.onc.1208998

By:

Homer, Craig;
Knight, Deborah A.;
Hananeia, Lynne;
Sheard, Philip;
Risk, Joanna;
Lasham, Annette;
Royds, Janice A.;
Braithwaite, Antony W.

Publication type:

Article

Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage.

Published in:

Cell Death & Disease, 2022, v. 13, n. 10, p. 1, doi. 10.1038/s41419-022-05349-9

By:

Steffens Reinhardt, Luiza;
Zhang, Xiajie;
Groen, Kira;
Morten, Brianna C.;
De Iuliis, Geoffry N.;
Braithwaite, Antony W.;
Bourdon, Jean-Christophe;
Avery-Kiejda, Kelly A.

Publication type:

Article

The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer.

Published in:

Cell Death & Disease, 2019, v. 10, n. 9, p. N.PAG, doi. 10.1038/s41419-019-1861-1

By:

Kazantseva, Marina;
Mehta, Sunali;
Eiholzer, Ramona A.;
Gimenez, Gregory;
Bowie, Sara;
Campbell, Hamish;
Reily-Bell, Ashley L.;
Roth, Imogen;
Ray, Sankalita;
Drummond, Catherine J.;
Reid, Glen;
Joruiz, Sebastien M.;
Wiles, Anna;
Morrin, Helen R.;
Reader, Karen L.;
Hung, Noelyn A.;
Baird, Margaret A.;
Slatter, Tania L.;
Braithwaite, Antony W.

Publication type:

Article

Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumor development.

Published in:

Journal of Pathology, 2018, v. 246, n. 1, p. 77, doi. 10.1002/path.5111

By:

Kazantseva, Marina;
Eiholzer, Ramona A.;
Mehta, Sunali;
Taha, Ahmad;
Bowie, Sara;
Roth, Imogen;
Zhou, Jean;
Joruiz, Sebastien M.;
Royds, Janice A.;
Hung, Noelyn A.;
Slatter, Tania L.;
Braithwaite, Antony W.

Publication type:

Article