Works matching AU Bozzi, Manuela

Results: 23

Misregulation of the Ubiquitin–Proteasome System and Autophagy in Muscular Dystrophies Associated with the Dystrophin–Glycoprotein Complex.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 721, doi. 10.3390/cells14100721

By:

Bozzi, Manuela;
Sciandra, Francesca;
Bigotti, Maria Giulia;
Brancaccio, Andrea

Publication type:

Article

Cover Image, Volume 39, Issue 2.

Published in:

Human Mutation, 2018, v. 39, n. 2, p. i, doi. 10.1002/humu.23391

By:

Signorino, Giulia;
Covaceuszach, Sonia;
Bozzi, Manuela;
Hübner, Wolfgang;
Mönkemöller, Viola;
Konarev, Petr V.;
Cassetta, Alberto;
Brancaccio, Andrea;
Sciandra, Francesca

Publication type:

Article

A dystroglycan mutation (p.Cys667Phe) associated to muscle‐eye‐brain disease with multicystic leucodystrophy results in ER‐retention of the mutant protein.

Published in:

Human Mutation, 2018, v. 39, n. 2, p. 266, doi. 10.1002/humu.23370

By:

Signorino, Giulia;
Covaceuszach, Sonia;
Bozzi, Manuela;
Hübner, Wolfgang;
Mönkemöller, Viola;
Konarev, Petr V.;
Cassetta, Alberto;
Brancaccio, Andrea;
Sciandra, Francesca

Publication type:

Article

The enzymatic processing of α-dystroglycan by MMP-2 is controlled by two anchoring sites distinct from the active site.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0192651

By:

Gioia, Magda;
Fasciglione, Giovanni Francesco;
Sbardella, Diego;
Sciandra, Francesca;
Casella, MariaLuisa;
Camerini, Serena;
Crescenzi, Marco;
Gori, Alessandro;
Tarantino, Umberto;
Cozza, Paola;
Brancaccio, Andrea;
Coletta, Massimo;
Bozzi, Manuela

Publication type:

Article

Live cell optical super-resolution microscopy of dystroglycan mutants as a model for dystroglycanopathies in multiple cell lines.

Published in:

Frontiers in Molecular Biosciences, 2025, p. 1, doi. 10.3389/fmolb.2025.1558170

By:

Sciandra, Francesca;
Bozzi, Manuela;
Witt, Alina;
Goffing, Paul;
Covaceuszach, Sonia;
Blaess, Sandra;
Cassetta, Alberto;
Bigotti, Maria Giulia;
Huser, Thomas;
Brancaccio, Andrea;
Hübner, Wolfgang

Publication type:

Article

Genetic Engineering of Dystroglycan in Animal Models of Muscular Dystrophy.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/635792

By:

Sciandra, Francesca;
Bigotti, Maria Giulia;
Giardina, Bruno;
Bozzi, Manuela;
Brancaccio, Andrea

Publication type:

Article

Enzymatic processing by MMP-2 and MMP-9 of wild-type and mutated mouse β-dystroglycan.

Published in:

IUBMB Life, 2012, v. 64, n. 12, p. 988, doi. 10.1002/iub.1095

By:

Sbardella, Diego;
Inzitari, Rosanna;
Iavarone, Federica;
Gioia, Magda;
Marini, Stefano;
Sciandra, Francesca;
Castagnola, Massimo;
Van den Steen, Philippe E.;
Opdenakker, Ghislain;
Giardina, Bruno;
Brancaccio, Andrea;
Coletta, Massimo;
Bozzi, Manuela

Publication type:

Article

Enzymatic processing of β-dystroglycan recombinant ectodomain by MMP-9: Identification of the main cleavage site.

Published in:

IUBMB Life, 2009, v. 61, n. 12, p. 1143, doi. 10.1002/iub.273

By:

Bozzi, Manuela;
Inzitari, Rosanna;
Sbardell, Diego;
Monaco, Susanna;
Pavoni, Ernesto;
Gioia, Magda;
Marini, Stefano;
Morlacchi, Simona;
Sciandra, Francesca;
Castagnola, Massimo;
Giardina, Bruno;
Brancaccio, Andrea;
Coletta, Massimo

Publication type:

Article

Proteasome Activity Is Affected by Fluctuations in Insulin-Degrading Enzyme Distribution.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132455

By:

Sbardella, Diego;
Tundo, Grazia Raffaella;
Sciandra, Francesca;
Bozzi, Manuela;
Gioia, Magda;
Ciaccio, Chiara;
Tarantino, Umberto;
Brancaccio, Andrea;
Coletta, Massimo;
Marini, Stefano

Publication type:

Article

The Structure of the T190M Mutant of Murine α-Dystroglycan at High Resolution: Insight into the Molecular Basis of a Primary Dystroglycanopathy.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0124277

By:

Bozzi, Manuela;
Cassetta, Alberto;
Covaceuszach, Sonia;
Bigotti, Maria Giulia;
Bannister, Saskia;
Hübner, Wolfgang;
Sciandra, Francesca;
Lamba, Doriano;
Brancaccio, Andrea

Publication type:

Article

Insights from Molecular Dynamics Simulations: Structural Basis for the V567D Mutation-Induced Instability of Zebrafish Alpha-Dystroglycan and Comparison with the Murine Model.

Published in:

2014

By:

Pirolli, Davide;
Sciandra, Francesca;
Bozzi, Manuela;
Giardina, Bruno;
Brancaccio, Andrea;
De Rosa, Maria Cristina

Publication type:

Calendar

The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of α-dystroglycan.

Published in:

PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0186110

By:

Covaceuszach, Sonia;
Bozzi, Manuela;
Bigotti, Maria Giulia;
Sciandra, Francesca;
Konarev, Petr V.;
Brancaccio, Andrea;
Cassetta, Alberto

Publication type:

Article

Structural flexibility of human α-dystroglycan.

Published in:

FEBS Open Bio, 2017, v. 7, n. 8, p. 1064, doi. 10.1002/2211-5463.12259

By:

Covaceuszach, Sonia;
Bozzi, Manuela;
Bigotti, Maria Giulia;
Sciandra, Francesca;
Konarev, Petr Valeryevich;
Brancaccio, Andrea;
Cassetta, Alberto

Publication type:

Article

Mutagenesis at the α–β interface impairs the cleavage of the dystroglycan precursor.

Published in:

FEBS Journal, 2009, v. 276, n. 17, p. 4933, doi. 10.1111/j.1742-4658.2009.07196.x

By:

Sciandra, Francesca;
Bozzi, Manuela;
Morlacchi, Simona;
Galtieri, Antonio;
Giardina, Bruno;
Brancaccio, Andrea

Publication type:

Article

Concerted mutation of Phe residues belonging to the β-dystroglycan ectodomain strongly inhibits the interaction with α-dystroglycan in vitro.

Published in:

FEBS Journal, 2006, v. 273, n. 21, p. 4929, doi. 10.1111/j.1742-4658.2006.05492.x

By:

Bozzi, Manuela;
Sciandra, Francesca;
Ferri, Lorenzo;
Torreri, Paola;
Pavoni, Ernesto;
Petrucci, Tamara C.;
Giardina, Bruno;
Brancaccio, Andrea

Publication type:

Article

Verbascoside Elicits Its Beneficial Effects by Enhancing Mitochondrial Spare Respiratory Capacity and the Nrf2/HO-1 Mediated Antioxidant System in a Murine Skeletal Muscle Cell Line.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 20, p. 15276, doi. 10.3390/ijms242015276

By:

Sciandra, Francesca;
Bottoni, Patrizia;
De Leo, Marinella;
Braca, Alessandra;
Brancaccio, Andrea;
Bozzi, Manuela

Publication type:

Article

Molecular Mechanisms Underlying Muscle Wasting in Huntington's Disease.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8314, doi. 10.3390/ijms21218314

By:

Bozzi, Manuela;
Sciandra, Francesca

Publication type:

Article

Probing the stability of the "naked" mucin-like domain of human α-dystroglycan.

Published in:

BMC Biochemistry, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2091-14-15

By:

Bozzi, Manuela;
Di Stasio, Enrico;
Luca Scaglione, Giovanni;
Desiderio, Claudia;
Martelli, Claudia;
Giardina, Bruno;
Sciandra, Francesca;
Brancaccio, Andrea

Publication type:

Article

Insertion of a myc-tag within α-dystroglycan domains improves its biochemical and microscopic detection.

Published in:

BMC Biochemistry, 2012, v. 13, n. 1, p. 14, doi. 10.1186/1471-2091-13-14

By:

Morlacchi, Simona;
Sciandra, Francesca;
Bigotti, Maria Giulia Bigotti;
Bozzi, Manuela;
Hï¿½bner, Wolfgang;
Galtieri, Antonio;
Giardina, Bruno;
Brancaccio, Andrea

Publication type:

Article

From adhesion complex to signaling hub: the dual role of dystroglycan.

Published in:

Frontiers in Molecular Biosciences, 2024, p. 1, doi. 10.3389/fmolb.2023.1325284

By:

Sciandra, Francesca;
Bozzi, Manuela;
Bigotti, Maria Giulia

Publication type:

Article

From adhesion complex to signaling hub: the dual role of dystroglycan.

Published in:

Frontiers in Molecular Biosciences, 2023, p. 1, doi. 10.3389/fmolb.2023.1325284

By:

Sciandra, Francesca;
Bozzi, Manuela;
Bigotti, Maria Giulia

Publication type:

Article

Evaluation of the effect of a floxed Neo cassette within the dystroglycan (Dag1) gene.

Published in:

BMC Research Notes, 2017, v. 10, p. 1, doi. 10.1186/s13104-017-2926-9

By:

Sciandra, Francesca;
Scicchitano, Bianca Maria;
Signorino, Giulia;
Bigotti, Maria Giulia;
Tavazzi, Barbara;
Lombardi, Francesca;
Bozzi, Manuela;
Sica, Gigliola;
Giardina, Bruno;
Blaess, Sandra;
Brancaccio, Andrea

Publication type:

Article

The effect of an ionic detergent on the natively unfolded β-dystroglycan ectodomain and on its interaction with α-dystroglycan.

Published in:

Protein Science: A Publication of the Protein Society, 2004, v. 13, n. 9, p. 2437, doi. 10.1110/ps.04762504

By:

Bozzi, Manuela;
Di Stasio, Enrico;
Cicero, Daniel O.;
Giardina, Bruno;
Paci, Maurizio;
Brancaccio, Andrea

Publication type:

Article