Found: 21
Select item for more details and to access through your institution.
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.83602
- By:
- Publication type:
- Article
Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation.
- Published in:
- Science Signaling, 2020, v. 13, n. 615, p. 1, doi. 10.1126/scisignal.aay7315
- By:
- Publication type:
- Article
Endogenous retinoid X receptor ligands in mouse hematopoietic cells.
- Published in:
- Science Signaling, 2017, v. 10, n. 503, p. 1, doi. 10.1126/scisignal.aan1011
- By:
- Publication type:
- Article
Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators.
- Published in:
- PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178678
- By:
- Publication type:
- Article
Toward physics‐based precision medicine: Exploiting protein dynamics to design new therapeutics and interpret variants.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 3, p. 1, doi. 10.1002/pro.4902
- By:
- Publication type:
- Article
Network models for molecular kinetics and their initial applications to human health.
- Published in:
- Cell Research, 2010, v. 20, n. 6, p. 622, doi. 10.1038/cr.2010.57
- By:
- Publication type:
- Article
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferatoractivated receptors to drive urothelial proliferation.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.30862.001
- By:
- Publication type:
- Article
The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31720-7
- By:
- Publication type:
- Article
A cryptic pocket in Ebola VP35 allosterically controls RNA binding.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29927-9
- By:
- Publication type:
- Article
A Role for Both Conformational Selection and Induced Fit in Ligand Binding by the LAO Protein.
- Published in:
- PLoS Computational Biology, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pcbi.1002054
- By:
- Publication type:
- Article
Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.
- Published in:
- Nature Immunology, 2012, v. 13, n. 12, p. 1187, doi. 10.1038/ni.2449
- By:
- Publication type:
- Article
Deep learning the structural determinants of protein biochemical properties by comparing structural ensembles with DiffNets.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23246-1
- By:
- Publication type:
- Article
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21953-3
- By:
- Publication type:
- Article
Simulated tempering yields insight into the low-resolution Rosetta scoring functions.
- Published in:
- Proteins, 2009, v. 74, n. 3, p. 777, doi. 10.1002/prot.22210
- By:
- Publication type:
- Article
Modelling proteins' hidden conformations to predict antibiotic resistance.
- Published in:
- Nature Communications, 2016, v. 7, n. 10, p. 12965, doi. 10.1038/ncomms12965
- By:
- Publication type:
- Article
The Roles of Entropy and Kinetics in Structure Prediction.
- Published in:
- PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005840
- By:
- Publication type:
- Article
Accurately modeling nanosecond protein dynamics requires at least microseconds of simulation.
- Published in:
- Journal of Computational Chemistry, 2016, v. 37, n. 6, p. 558, doi. 10.1002/jcc.23973
- By:
- Publication type:
- Article
Propagation of the Allosteric Modulation Induced by Sodium in the δ-Opioid Receptor.
- Published in:
- Chemistry - A European Journal, 2017, v. 23, n. 19, p. 4615, doi. 10.1002/chem.201605575
- By:
- Publication type:
- Article
Corrigendum: Cloud-based simulations on Google Exacycle reveal ligand modulation of GPCR activation pathways.
- Published in:
- Nature Chemistry, 2015, v. 7, n. 9, p. 759, doi. 10.1038/nchem.2272
- By:
- Publication type:
- Article
Cloud-based simulations on Google Exacycle reveal ligand modulation of GPCR activation pathways.
- Published in:
- Nature Chemistry, 2014, v. 6, n. 1, p. 15, doi. 10.1038/nchem.1821
- By:
- Publication type:
- Article
Probing the Nanosecond Dynamics of a Designed Three-Stranded Beta-Sheet with a Massively Parallel Molecular Dynamics Simulation.
- Published in:
- International Journal of Molecular Sciences, 2009, v. 10, n. 3, p. 1013, doi. 10.3390/ijms10031013
- By:
- Publication type:
- Article