Works by Bowie, Andrew G.

Results: 32

IFI16 is an innate immune sensor for intracellular DNA.

Published in:

Nature Immunology, 2010, v. 11, n. 11, p. 997, doi. 10.1038/ni.1932

By:

Unterholzner, Leonie;
Keating, Sinead E;
Baran, Marcin;
Horan, Kristy A;
Jensen, Søren B;
Sharma, Shruti;
Sirois, Cherilyn M;
Jin, Tengchuan;
Latz, Eicke;
Xiao, T Sam;
Fitzgerald, Katherine A;
Paludan, Søren R;
Bowie, Andrew G

Publication type:

Article

TRIM-ing down Tolls.

Published in:

Nature Immunology, 2008, v. 9, n. 4, p. 348, doi. 10.1038/ni0408-348

By:

Bowie, Andrew G

Publication type:

Article

The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling.

Published in:

Nature Immunology, 2006, v. 7, n. 10, p. 1074, doi. 10.1038/ni1382

By:

Carty, Michael;
Goodbody, Rory;
Schröder, Martina;
Stack, Julianne;
Moynagh, Paul N.;
Bowie, Andrew G.

Publication type:

Article

Multi-omics characterization of the monkeypox virus infection.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51074-6

By:

Huang, Yiqi;
Bergant, Valter;
Grass, Vincent;
Emslander, Quirin;
Hamad, M. Sabri;
Hubel, Philipp;
Mergner, Julia;
Piras, Antonio;
Krey, Karsten;
Henrici, Alexander;
Öllinger, Rupert;
Tesfamariam, Yonas M.;
Dalla Rosa, Ilaria;
Bunse, Till;
Sutter, Gerd;
Ebert, Gregor;
Schmidt, Florian I.;
Way, Michael;
Rad, Roland;
Bowie, Andrew G.

Publication type:

Article

Human Coronavirus 229E Infection Inactivates Pyroptosis Executioner Gasdermin D but Ultimately Leads to Lytic Cell Death Partly Mediated by Gasdermin E.

Published in:

Viruses (1999-4915), 2024, v. 16, n. 6, p. 898, doi. 10.3390/v16060898

By:

Martiáñez-Vendrell, Xavier;
Bloeme-ter Horst, Jonna;
Hutchinson, Roy;
Guy, Coralie;
Bowie, Andrew G.;
Kikkert, Marjolein

Publication type:

Article

Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27701-x

By:

Gu, Lili;
Casserly, David;
Brady, Gareth;
Carpenter, Susan;
Bracken, Adrian P.;
Fitzgerald, Katherine A.;
Unterholzner, Leonie;
Bowie, Andrew G.

Publication type:

Article

Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis.

Published in:

2022

By:

McElroy, Aoife N.;
Invernizzi, Rachele;
Laskowska, Joanna W.;
O'Neill, Andrew;
Doroudian, Mohammad;
Moghoofei, Mohsen;
Mostafaei, Shayan;
Feng Li;
Przybylski, Alexander A.;
O'Dwyer, David N.;
Bowie, Andrew G.;
Fallon, Padraic G.;
Maher, Toby M.;
Hogaboam, Cory M.;
Molyneaux, Philip L.;
Hirani, Nik;
Armstrong, Michelle E.;
Donnelly, Seamas C.;
Li, Feng

Publication type:

journal article

Candidate role for Toll-like receptor 3 L412F polymorphism and infection in acute exacerbation of idiopathic pulmonary fibrosis.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2022, v. 205, n. 5, p. E1, doi. 10.1164/rccm.202010-3880oc

By:

McElroy, Aoife N.;
Invernizzi, Rachele;
Laskowska, Joanna W.;
O'Neill, Andrew;
Doroudian, Mohammad;
Moghoofei, Mohsen;
Mostafaei, Shayan;
Feng Li;
Przybylksi, Alexander A.;
O'Dwyer, David N.;
Bowie, Andrew G.;
Fallon, Padraic G.;
Maher, Toby M.;
Hogaboam, Cory M.;
Molyneaux, Philip L.;
Hirani, Nik;
Armstrong, Michelle E.;
Donnelly, Seamas C.

Publication type:

Article

Recognition of herpesviruses by the innate immune system.

Published in:

Nature Reviews Immunology, 2013, v. 13, n. 8, p. 614, doi. 10.1038/nri3497

By:

Paludan, Søren R.;
Bowie, Andrew G.;
Horan, Kristy A.;
Fitzgerald, Katherine A.

Publication type:

Article

The history of Toll-like receptors - redefining innate immunity.

Published in:

Nature Reviews Immunology, 2013, v. 13, n. 6, p. 453, doi. 10.1038/nri3446

By:

O'Neill, Luke A. J.;
Golenbock, Douglas;
Bowie, Andrew G.

Publication type:

Article

Alum Activates the Bovine NLRP3 Inflammasome.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01494

By:

Harte, Ciaran;
Gorman, Aoife L.;
McCluskey, S.;
Carty, Michael;
Bowie, Andrew G.;
Scott, C. J.;
Meade, Kieran G.;
Lavelle, Ed C.

Publication type:

Article

Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12522, doi. 10.3390/ijms232012522

By:

Singh, Saravjeet;
O'Reilly, Sophie;
Gewaid, Hossam;
Bowie, Andrew G.;
Gautier, Virginie;
Worrall, D. Margaret

Publication type:

Article

SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1606, doi. 10.3390/ijms23031606

By:

Finnegan, Laura K.;
Chadderton, Naomi;
Kenna, Paul F.;
Palfi, Arpad;
Carty, Michael;
Bowie, Andrew G.;
Millington-Ward, Sophia;
Farrar, G. Jane

Publication type:

Article

DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease.

Published in:

Glia (0894-1491), 2015, v. 63, n. 5, p. 812, doi. 10.1002/glia.22786

By:

Cox, Donal J.;
Field, Robert H.;
Williams, David G.;
Baran, Marcin;
Bowie, Andrew G.;
Cunningham, Colm;
Dunne, Aisling

Publication type:

Article

Recognition of herpesviruses by the innate immune system.

Published in:

2011

By:

Paludan, Søren R.;
Bowie, Andrew G.;
Horan, Kristy A.;
Fitzgerald, Katherine A.;
Paludan, Søren R

Publication type:

research

Viral evasion and subversion of pattern-recognition receptor signalling.

Published in:

2008

By:

Bowie, Andrew G.;
Unterholzner, Leonie

Publication type:

journal article

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling.

Published in:

Nature Reviews Immunology, 2007, v. 7, n. 5, p. 353, doi. 10.1038/nri2079

By:

O'Neill, Luke A. J.;
Bowie, Andrew G.

Publication type:

Article

Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro.

Published in:

Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 230, doi. 10.1186/1742-2094-9-230

By:

Leow-Dyke, Sophie;
Allen, Charlotte;
Denes, Denes;
Nilsson, Olov;
Maysami, Samaneh;
Bowie, Andrew G.;
Rothwell, Nancy J.;
Pinteaux, Emmanuel

Publication type:

Article

Viral appropriation of apoptotic and NF-κB signaling pathways.

Published in:

Journal of Cellular Biochemistry, 2004, v. 91, n. 6, p. 1099, doi. 10.1002/jcb.20026

By:

Andrew G. Bowie;
Jun Zhan;
William L. Marshall

Publication type:

Article

Poxvirus Targeting of E3 Ligase β-TrCP by Molecular Mimicry: A Mechanism to Inhibit NF-κB Activation and Promote Immune Evasion and Virulence.

Published in:

PLoS Pathogens, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.ppat.1003183

By:

Mansur, Daniel S.;
Maluquer de Motes, Carlos;
Unterholzner, Leonie;
Sumner, Rebecca P.;
Ferguson, Brian J.;
Hongwei Ren;
Strnadova, Pavla;
Bowie, Andrew G.;
Smith, Geoffrey L.

Publication type:

Article

Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7.

Published in:

PLoS Pathogens, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.ppat.1002247

By:

Unterholzner, Leonie;
Sumner, Rebecca P.;
Baran, Marcin;
Hongwei Ren;
Mansur, Daniel S.;
Bourke, Nollaig M.;
Randow, Felix;
Smith, Geoffrey L.;
Bowie, Andrew G.

Publication type:

Article

Rad50 and CARD9, missing links in cytosolic DNA-stimulated inflammation.

Published in:

Nature Immunology, 2014, v. 15, n. 6, p. 534, doi. 10.1038/ni.2894

By:

Bowie, Andrew G

Publication type:

Article

Innate sensing of bacterial cyclic dinucleotides: more than just STING.

Published in:

Nature Immunology, 2012, v. 13, n. 12, p. 1137, doi. 10.1038/ni.2469

By:

Bowie, Andrew G

Publication type:

Article

Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake.

Published in:

Nature Immunology, 2011, v. 12, n. 9, p. 805, doi. 10.1038/ni.0911-805

By:

Paludan, Søren R;
Levy, Ofer;
Bowie, Andrew G

Publication type:

Article

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.

Published in:

Nature Communications, 2017, v. 8, n. 2, p. 14392, doi. 10.1038/ncomms14392

By:

Almine, Jessica F.;
O'Hare, Craig A. J.;
Dunphy, Gillian;
Haga, Ismar R.;
Naik, Rangeetha J.;
Atrih, Abdelmadjid;
Connolly, Dympna J.;
Taylor, Jordan;
Kelsall, Ian R.;
Bowie, Andrew G.;
Beard, Philippa M.;
Unterholzner, Leonie

Publication type:

Article

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation.

Published in:

EMBO Journal, 2008, v. 27, n. 15, p. 2147, doi. 10.1038/emboj.2008.143

By:

Schröder, Martina;
Baran, Marcin;
Bowie, Andrew G.

Publication type:

Article

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Published in:

Nature, 2001, v. 413, n. 6851, p. 78, doi. 10.1038/35092578

By:

Fitzgerald, Katherine A.;
Palsson-McDermott, Eva M.;
Bowie, Andrew G.;
Jefferies, Caroline A.;
Mansell, Ashley S.;
Brady, Gareth;
Brint, Elizabeth;
Dunne, Aisling;
Gray, Pearl;
Harte, Mary T.;
McMurray, Diane;
Smith, Dirk E.;
Sims, John E.;
Bird, Timothy A.

Publication type:

Article

Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca<sup>2+</sup> signaling during T cell activation.

Published in:

Science Signaling, 2021, v. 14, n. 709, p. 1, doi. 10.1126/scisignal.abe3800

By:

Gu, Feng;
Krüger, Aileen;
Roggenkamp, Hannes G.;
Alpers, Rick;
Lodygin, Dmitri;
Jaquet, Vincent;
Möckl, Franziska;
Hernandez C., Lola C.;
Winterberg, Kai;
Bauche, Andreas;
Rosche, Anette;
Grasberger, Helmut;
Kao, John Y.;
Schetelig, Daniel;
Werner, René;
Schröder, Katrin;
Carty, Michael;
Bowie, Andrew G.;
Huber, Samuel;
Meier, Chris

Publication type:

Article

SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration.

Published in:

Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.852114

By:

Gibbons, Luke;
Ozaki, Ema;
Greene, Chris;
Trappe, Anne;
Carty, Michael;
Coppinger, Judith A.;
Bowie, Andrew G.;
Campbell, Matthew;
Doyle, Sarah L.

Publication type:

Article

Viral immune modulators perturb the human molecular network by common and unique strategies.

Published in:

Nature, 2012, v. 487, n. 7408, p. 486, doi. 10.1038/nature11289

By:

Pichlmair, Andreas;
Kandasamy, Kumaran;
Alvisi, Gualtiero;
Mulhern, Orla;
Sacco, Roberto;
Habjan, Matthias;
Binder, Marco;
Stefanovic, Adrijana;
Eberle, Carol-Ann;
Goncalves, Adriana;
Bürckstümmer, Tilmann;
Müller, André C.;
Fauster, Astrid;
Holze, Cathleen;
Lindsten, Kristina;
Goodbourn, Stephen;
Kochs, Georg;
Weber, Friedemann;
Bartenschlager, Ralf;
Bowie, Andrew G.

Publication type:

Article

Chemical- and photo-activation of protein-protein thiol-ene coupling for protein profiling.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01412-6

By:

Campaniҫo, André;
Baran, Marcin;
Bowie, Andrew G.;
Longley, Daniel B.;
Harrison, Timothy;
McGouran, Joanna F.

Publication type:

Article

Unexpected roles for DEAD-box protein 3 in viral RNA sensing pathways.

Published in:

European Journal of Immunology, 2010, v. 40, n. 4, p. 933, doi. 10.1002/eji.201040447

By:

Mulhern, Orla;
Bowie, Andrew G.

Publication type:

Article