Works by Bowie, Andrew G.

Results: 32

DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease.
Published in:
Glia, 2015, v. 63, n. 5, p. 812, doi. 10.1002/glia.22786
By:
- Cox, Donal J.;
- Field, Robert H.;
- Williams, David G.;
- Baran, Marcin;
- Bowie, Andrew G.;
- Cunningham, Colm;
- Dunne, Aisling
Publication type:
Article
Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake.
Published in:
Nature Immunology, 2011, v. 12, n. 9, p. 805, doi. 10.1038/ni.0911-805
By:
- Paludan, Søren R;
- Levy, Ofer;
- Bowie, Andrew G
Publication type:
Article
IFI16 is an innate immune sensor for intracellular DNA.
Published in:
Nature Immunology, 2010, v. 11, n. 11, p. 997, doi. 10.1038/ni.1932
By:
- Unterholzner, Leonie;
- Keating, Sinead E;
- Baran, Marcin;
- Horan, Kristy A;
- Jensen, Søren B;
- Sharma, Shruti;
- Sirois, Cherilyn M;
- Jin, Tengchuan;
- Latz, Eicke;
- Xiao, T Sam;
- Fitzgerald, Katherine A;
- Paludan, Søren R;
- Bowie, Andrew G
Publication type:
Article
TRIM-ing down Tolls.
Published in:
Nature Immunology, 2008, v. 9, n. 4, p. 348, doi. 10.1038/ni0408-348
By:
- Bowie, Andrew G
Publication type:
Article
The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling.
Published in:
Nature Immunology, 2006, v. 7, n. 10, p. 1074, doi. 10.1038/ni1382
By:
- Carty, Michael;
- Goodbody, Rory;
- Schröder, Martina;
- Stack, Julianne;
- Moynagh, Paul N.;
- Bowie, Andrew G.
Publication type:
Article
Viral appropriation of apoptotic and NF-κB signaling pathways.
Published in:
Journal of Cellular Biochemistry, 2004, v. 91, n. 6, p. 1099, doi. 10.1002/jcb.20026
By:
- Andrew G. Bowie;
- Jun Zhan;
- William L. Marshall
Publication type:
Article
The history of Toll-like receptors - redefining innate immunity.
Published in:
Nature Reviews Immunology, 2013, v. 13, n. 6, p. 453, doi. 10.1038/nri3446
By:
- O'Neill, Luke A. J.;
- Golenbock, Douglas;
- Bowie, Andrew G.
Publication type:
Article
Recognition of herpesviruses by the innate immune system.
Published in:
2011
By:
- Paludan, Søren R.;
- Bowie, Andrew G.;
- Horan, Kristy A.;
- Fitzgerald, Katherine A.;
- Paludan, Søren R
Publication type:
research
Viral evasion and subversion of pattern-recognition receptor signalling.
Published in:
2008
By:
- Bowie, Andrew G.;
- Unterholzner, Leonie
Publication type:
journal article
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling.
Published in:
Nature Reviews Immunology, 2007, v. 7, n. 5, p. 353, doi. 10.1038/nri2079
By:
- O'Neill, Luke A. J.;
- Bowie, Andrew G.
Publication type:
Article
Alum Activates the Bovine NLRP3 Inflammasome.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01494
By:
- Harte, Ciaran;
- Gorman, Aoife L.;
- McCluskey, S.;
- Carty, Michael;
- Bowie, Andrew G.;
- Scott, C. J.;
- Meade, Kieran G.;
- Lavelle, Ed C.
Publication type:
Article
Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis.
Published in:
2022
By:
- McElroy, Aoife N.;
- Invernizzi, Rachele;
- Laskowska, Joanna W.;
- O'Neill, Andrew;
- Doroudian, Mohammad;
- Moghoofei, Mohsen;
- Mostafaei, Shayan;
- Feng Li;
- Przybylski, Alexander A.;
- O'Dwyer, David N.;
- Bowie, Andrew G.;
- Fallon, Padraic G.;
- Maher, Toby M.;
- Hogaboam, Cory M.;
- Molyneaux, Philip L.;
- Hirani, Nik;
- Armstrong, Michelle E.;
- Donnelly, Seamas C.;
- Li, Feng
Publication type:
journal article
Candidate role for Toll-like receptor 3 L412F polymorphism and infection in acute exacerbation of idiopathic pulmonary fibrosis.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2022, v. 205, n. 5, p. E1, doi. 10.1164/rccm.202010-3880oc
By:
- McElroy, Aoife N.;
- Invernizzi, Rachele;
- Laskowska, Joanna W.;
- O'Neill, Andrew;
- Doroudian, Mohammad;
- Moghoofei, Mohsen;
- Mostafaei, Shayan;
- Feng Li;
- Przybylksi, Alexander A.;
- O'Dwyer, David N.;
- Bowie, Andrew G.;
- Fallon, Padraic G.;
- Maher, Toby M.;
- Hogaboam, Cory M.;
- Molyneaux, Philip L.;
- Hirani, Nik;
- Armstrong, Michelle E.;
- Donnelly, Seamas C.
Publication type:
Article
Poxvirus Targeting of E3 Ligase β-TrCP by Molecular Mimicry: A Mechanism to Inhibit NF-κB Activation and Promote Immune Evasion and Virulence.
Published in:
PLoS Pathogens, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.ppat.1003183
By:
- Mansur, Daniel S.;
- Maluquer de Motes, Carlos;
- Unterholzner, Leonie;
- Sumner, Rebecca P.;
- Ferguson, Brian J.;
- Hongwei Ren;
- Strnadova, Pavla;
- Bowie, Andrew G.;
- Smith, Geoffrey L.
Publication type:
Article
Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7.
Published in:
PLoS Pathogens, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.ppat.1002247
By:
- Unterholzner, Leonie;
- Sumner, Rebecca P.;
- Baran, Marcin;
- Hongwei Ren;
- Mansur, Daniel S.;
- Bourke, Nollaig M.;
- Randow, Felix;
- Smith, Geoffrey L.;
- Bowie, Andrew G.
Publication type:
Article
Viral immune modulators perturb the human molecular network by common and unique strategies.
Published in:
Nature, 2012, v. 487, n. 7408, p. 486, doi. 10.1038/nature11289
By:
- Pichlmair, Andreas;
- Kandasamy, Kumaran;
- Alvisi, Gualtiero;
- Mulhern, Orla;
- Sacco, Roberto;
- Habjan, Matthias;
- Binder, Marco;
- Stefanovic, Adrijana;
- Eberle, Carol-Ann;
- Goncalves, Adriana;
- Bürckstümmer, Tilmann;
- Müller, André C.;
- Fauster, Astrid;
- Holze, Cathleen;
- Lindsten, Kristina;
- Goodbourn, Stephen;
- Kochs, Georg;
- Weber, Friedemann;
- Bartenschlager, Ralf;
- Bowie, Andrew G.
Publication type:
Article
Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27701-x
By:
- Gu, Lili;
- Casserly, David;
- Brady, Gareth;
- Carpenter, Susan;
- Bracken, Adrian P.;
- Fitzgerald, Katherine A.;
- Unterholzner, Leonie;
- Bowie, Andrew G.
Publication type:
Article
Human Coronavirus 229E Infection Inactivates Pyroptosis Executioner Gasdermin D but Ultimately Leads to Lytic Cell Death Partly Mediated by Gasdermin E.
Published in:
Viruses (1999-4915), 2024, v. 16, n. 6, p. 898, doi. 10.3390/v16060898
By:
- Martiáñez-Vendrell, Xavier;
- Bloeme-ter Horst, Jonna;
- Hutchinson, Roy;
- Guy, Coralie;
- Bowie, Andrew G.;
- Kikkert, Marjolein
Publication type:
Article
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca<sup>2+</sup> signaling during T cell activation.
Published in:
Science Signaling, 2021, v. 14, n. 709, p. 1, doi. 10.1126/scisignal.abe3800
By:
- Gu, Feng;
- Krüger, Aileen;
- Roggenkamp, Hannes G.;
- Alpers, Rick;
- Lodygin, Dmitri;
- Jaquet, Vincent;
- Möckl, Franziska;
- Hernandez C., Lola C.;
- Winterberg, Kai;
- Bauche, Andreas;
- Rosche, Anette;
- Grasberger, Helmut;
- Kao, John Y.;
- Schetelig, Daniel;
- Werner, René;
- Schröder, Katrin;
- Carty, Michael;
- Bowie, Andrew G.;
- Huber, Samuel;
- Meier, Chris
Publication type:
Article
Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation.
Published in:
EMBO Journal, 2008, v. 27, n. 15, p. 2147, doi. 10.1038/emboj.2008.143
By:
- Schröder, Martina;
- Baran, Marcin;
- Bowie, Andrew G.
Publication type:
Article
Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro.
Published in:
Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 230, doi. 10.1186/1742-2094-9-230
By:
- Leow-Dyke, Sophie;
- Allen, Charlotte;
- Denes, Denes;
- Nilsson, Olov;
- Maysami, Samaneh;
- Bowie, Andrew G.;
- Rothwell, Nancy J.;
- Pinteaux, Emmanuel
Publication type:
Article
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.
Published in:
Nature Communications, 2017, v. 8, n. 2, p. 14392, doi. 10.1038/ncomms14392
By:
- Almine, Jessica F.;
- O'Hare, Craig A. J.;
- Dunphy, Gillian;
- Haga, Ismar R.;
- Naik, Rangeetha J.;
- Atrih, Abdelmadjid;
- Connolly, Dympna J.;
- Taylor, Jordan;
- Kelsall, Ian R.;
- Bowie, Andrew G.;
- Beard, Philippa M.;
- Unterholzner, Leonie
Publication type:
Article
Recognition of herpesviruses by the innate immune system.
Published in:
Nature Reviews Immunology, 2013, v. 13, n. 8, p. 614, doi. 10.1038/nri3497
By:
- Paludan, Søren R.;
- Bowie, Andrew G.;
- Horan, Kristy A.;
- Fitzgerald, Katherine A.
Publication type:
Article
Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12522, doi. 10.3390/ijms232012522
By:
- Singh, Saravjeet;
- O'Reilly, Sophie;
- Gewaid, Hossam;
- Bowie, Andrew G.;
- Gautier, Virginie;
- Worrall, D. Margaret
Publication type:
Article
SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1606, doi. 10.3390/ijms23031606
By:
- Finnegan, Laura K.;
- Chadderton, Naomi;
- Kenna, Paul F.;
- Palfi, Arpad;
- Carty, Michael;
- Bowie, Andrew G.;
- Millington-Ward, Sophia;
- Farrar, G. Jane
Publication type:
Article
Chemical- and photo-activation of protein-protein thiol-ene coupling for protein profiling.
Published in:
Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01412-6
By:
- Campaniҫo, André;
- Baran, Marcin;
- Bowie, Andrew G.;
- Longley, Daniel B.;
- Harrison, Timothy;
- McGouran, Joanna F.
Publication type:
Article
Multi-omics characterization of the monkeypox virus infection.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51074-6
By:
- Huang, Yiqi;
- Bergant, Valter;
- Grass, Vincent;
- Emslander, Quirin;
- Hamad, M. Sabri;
- Hubel, Philipp;
- Mergner, Julia;
- Piras, Antonio;
- Krey, Karsten;
- Henrici, Alexander;
- Öllinger, Rupert;
- Tesfamariam, Yonas M.;
- Dalla Rosa, Ilaria;
- Bunse, Till;
- Sutter, Gerd;
- Ebert, Gregor;
- Schmidt, Florian I.;
- Way, Michael;
- Rad, Roland;
- Bowie, Andrew G.
Publication type:
Article
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
Published in:
Nature, 2001, v. 413, n. 6851, p. 78, doi. 10.1038/35092578
By:
- Fitzgerald, Katherine A.;
- Palsson-McDermott, Eva M.;
- Bowie, Andrew G.;
- Jefferies, Caroline A.;
- Mansell, Ashley S.;
- Brady, Gareth;
- Brint, Elizabeth;
- Dunne, Aisling;
- Gray, Pearl;
- Harte, Mary T.;
- McMurray, Diane;
- Smith, Dirk E.;
- Sims, John E.;
- Bird, Timothy A.
Publication type:
Article
Rad50 and CARD9, missing links in cytosolic DNA-stimulated inflammation.
Published in:
Nature Immunology, 2014, v. 15, n. 6, p. 534, doi. 10.1038/ni.2894
By:
- Bowie, Andrew G
Publication type:
Article
Innate sensing of bacterial cyclic dinucleotides: more than just STING.
Published in:
Nature Immunology, 2012, v. 13, n. 12, p. 1137, doi. 10.1038/ni.2469
By:
- Bowie, Andrew G
Publication type:
Article
Unexpected roles for DEAD-box protein 3 in viral RNA sensing pathways.
Published in:
European Journal of Immunology, 2010, v. 40, n. 4, p. 933, doi. 10.1002/eji.201040447
By:
- Mulhern, Orla;
- Bowie, Andrew G.
Publication type:
Article
SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration.
Published in:
Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.852114
By:
- Gibbons, Luke;
- Ozaki, Ema;
- Greene, Chris;
- Trappe, Anne;
- Carty, Michael;
- Coppinger, Judith A.;
- Bowie, Andrew G.;
- Campbell, Matthew;
- Doyle, Sarah L.
Publication type:
Article