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Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis‐multivariable Mendelian randomization to GLP1R gene region.
- Published in:
- Genetic Epidemiology, 2024, v. 48, n. 4, p. 151, doi. 10.1002/gepi.22551
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- Article
Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes.
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- Diabetologia, 2024, v. 67, n. 5, p. 822, doi. 10.1007/s00125-024-06099-3
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- Article
SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4426, doi. 10.3390/ijms25084426
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- Article
Smoking during pregnancy and its effect on placental weight: a Mendelian randomization study.
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- BMC Pregnancy & Childbirth, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12884-024-06431-0
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- Article
Hyperglycaemia is a causal risk factor for upper limb pathologies.
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- International Journal of Epidemiology, 2024, v. 53, n. 1, p. 1, doi. 10.1093/ije/dyad187
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- Article
Dirichlet process mixture models to impute missing predictor data in counterfactual prediction models: an application to predict optimal type 2 diabetes therapy.
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- BMC Medical Informatics & Decision Making, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12911-023-02400-3
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- Article
Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study.
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- BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03211-z
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- Article
Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study.
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- BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03001-7
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- Article
Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study.
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- BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03001-7
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- Article
Association between circadian physical activity patterns and mortality in the UK Biobank.
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- International Journal of Behavioral Nutrition & Physical Activity, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12966-023-01508-z
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- Article
Mid‐life leukocyte telomere length and dementia risk: An observational and mendelian randomization study of 435,046 UK Biobank participants.
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- Aging Cell, 2023, v. 22, n. 7, p. 1, doi. 10.1111/acel.13808
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- Article
Sample-constrained partial identification with application to selection bias.
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- Biometrika, 2023, v. 110, n. 2, p. 485, doi. 10.1093/biomet/asac042
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- Article
Sparse dimensionality reduction approaches in Mendelian randomisation with highly correlated exposures.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.80063
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- Article
Weak and pleiotropy robust sex‐stratified Mendelian randomization in the one sample and two sample settings.
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- Genetic Epidemiology, 2023, v. 47, n. 2, p. 135, doi. 10.1002/gepi.22512
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- Article
Calcium‐channel blockers: Clinical outcome associations with reported pharmacogenetics variants in 32 000 patients.
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- British Journal of Clinical Pharmacology, 2023, v. 89, n. 2, p. 853, doi. 10.1111/bcp.15541
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- Article
Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization study.
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- International Journal of Epidemiology, 2023, v. 52, n. 1, p. 178, doi. 10.1093/ije/dyac186
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- Article
Islet Autoantibody Level Distribution in Type 1 Diabetes and Their Association With Genetic and Clinical Characteristics.
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- Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 12, p. e4341, doi. 10.1210/clinem/dgac507
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- Article
Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions.
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- PLoS ONE, 2022, v. 17, n. 8, p. 1, doi. 10.1371/journal.pone.0271933
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- Article
Should RECOVERY have used response adaptive randomisation? Evidence from a simulation study.
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- BMC Medical Research Methodology, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12874-022-01691-w
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- Article
Statin treatment effectiveness and the SLCO1B1*5 reduced function genotype: Long‐term outcomes in women and men.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 7, p. 3230, doi. 10.1111/bcp.15245
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- Article
Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study.
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- 2022
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- Publication type:
- journal article
Sensitivity to missing not at random dropout in clinical trials: Use and interpretation of the trimmed means estimator.
- Published in:
- Statistics in Medicine, 2022, v. 41, n. 8, p. 1462, doi. 10.1002/sim.9299
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- Article
Profile‐likelihood Bayesian model averaging for two‐sample summary data Mendelian randomization in the presence of horizontal pleiotropy.
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- Statistics in Medicine, 2022, v. 41, n. 6, p. 1100, doi. 10.1002/sim.9320
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- Article
Testing and correcting for weak and pleiotropic instruments in two‐sample multivariable Mendelian randomization.
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- Statistics in Medicine, 2021, v. 40, n. 25, p. 5434, doi. 10.1002/sim.9133
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- Article
Connecting Instrumental Variable methods for causal inference to the Estimand Framework.
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- Statistics in Medicine, 2021, v. 40, n. 25, p. 5605, doi. 10.1002/sim.9143
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- Article
The use of two-sample methods for Mendelian randomization analyses on single large datasets.
- Published in:
- 2021
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- Publication type:
- journal article
The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research.
- Published in:
- PLoS Genetics, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.pgen.1009783
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- Article
The confidence interval method for selecting valid instrumental variables.
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- Journal of the Royal Statistical Society: Series B (Statistical Methodology), 2021, v. 83, n. 4, p. 752, doi. 10.1111/rssb.12449
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- Article
Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data.
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- PLoS Genetics, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.pgen.1009703
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- Article
Causal inference for heritable phenotypic risk factors using heterogeneous genetic instruments.
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- PLoS Genetics, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.pgen.1009575
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- Article
188-LB: Type 2 Diabetes Is Genetically Correlated with Multiple Long-Term Conditions but These Correlations Are Only Partly Explained by BMI.
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- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-188-LB
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- Article
Mendelian randomisation with coarsened exposures.
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- Genetic Epidemiology, 2021, v. 45, n. 3, p. 338, doi. 10.1002/gepi.22376
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- Article
Realising the full potential of MR-PHeWAS in cancer.
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- 2021
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- Publication type:
- editorial
Low Vitamin D Levels and Risk of Incident Delirium in 351,000 Older UK Biobank Participants.
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- Journal of the American Geriatrics Society, 2021, v. 69, n. 2, p. 365, doi. 10.1111/jgs.16853
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- Article
Corrigendum to: An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings.
- Published in:
- 2020
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- Publication type:
- journal article
The median and the mode as robust meta‐analysis estimators in the presence of small‐study effects and outliers.
- Published in:
- Research Synthesis Methods, 2020, v. 11, n. 3, p. 397, doi. 10.1002/jrsm.1402
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- Article
Meta‐analysis and Mendelian randomization: A review.
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- Research Synthesis Methods, 2019, v. 10, n. 4, p. 486, doi. 10.1002/jrsm.1346
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- Article
Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11456-7
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- Article
Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10679-y
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- Article
Detecting and correcting for bias in Mendelian randomization analyses using Gene-by-Environment interactions.
- Published in:
- 2019
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- Publication type:
- journal article
An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings.
- Published in:
- 2019
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- Publication type:
- journal article
Improving the accuracy of two-sample summary-data Mendelian randomization: moving beyond the NOME assumption.
- Published in:
- 2019
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- Publication type:
- journal article
Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease.
- Published in:
- PLoS ONE, 2019, v. 14, n. 5, p. 1, doi. 10.1371/journal.pone.0216222
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- Publication type:
- Article
Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08917-4
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- Publication type:
- Article
A comparison of heterogeneity variance estimators in simulated random‐effects meta‐analyses.
- Published in:
- Research Synthesis Methods, 2019, v. 10, n. 1, p. 83, doi. 10.1002/jrsm.1316
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- Publication type:
- Article
Invited Commentary: Detecting Individual and Global Horizontal Pleiotropy in Mendelian Randomization—A Job for the Humble Heterogeneity Statistic?
- Published in:
- American Journal of Epidemiology, 2018, v. 187, n. 12, p. 2681, doi. 10.1093/aje/kwy185
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- Article
Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression.
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- 2018
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- Publication type:
- journal article
Adiposity-Mortality Relationships in Type 2 Diabetes, Coronary Heart Disease, and Cancer Subgroups in the UK Biobank, and Their Modification by Smoking.
- Published in:
- 2018
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- Publication type:
- journal article
Age at puberty and risk of asthma: A Mendelian randomisation study.
- Published in:
- 2018
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- Publication type:
- journal article
Evaluating the potential role of pleiotropy in Mendelian randomization studies.
- Published in:
- Human Molecular Genetics, 2018, v. 27, p. R195, doi. 10.1093/hmg/ddy163
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- Publication type:
- Article