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Influence of age on the efficacy of pharmacologic treatments on fracture risk reduction and increases in BMD: RCT results from the FNIH-ASBMR-SABRE project.
- Published in:
- Journal of Bone & Mineral Research, 2024, v. 39, n. 5, p. 544, doi. 10.1093/jbmr/zjae040
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- Publication type:
- Article
Fracture risk based on high-resolution peripheral quantitative computed tomography measures does not vary with age in older adults—the bone microarchitecture international consortium prospective cohort study.
- Published in:
- Journal of Bone & Mineral Research, 2024, v. 39, n. 5, p. 561, doi. 10.1093/jbmr/zjae033
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- Publication type:
- Article
Factors Associated With High-Risk and Low-Risk Bone Stress Injury in Female Runners: Implications for Risk Factor Stratification and Management.
- Published in:
- Orthopaedic Journal of Sports Medicine, 2024, v. 12, n. 5, p. 1, doi. 10.1177/23259671241246227
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- Publication type:
- Article
Adaptation to full weight‐bearing following disuse in rats: The impact of biological sex on musculoskeletal recovery.
- Published in:
- Physiological Reports, 2024, v. 12, n. 4, p. 1, doi. 10.14814/phy2.15938
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- Publication type:
- Article
Use of noninvasive imaging to identify causes of skeletal fragility in adults with diabetes: a review.
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- JBMR Plus, 2024, v. 8, n. 2, p. 1, doi. 10.1093/jbmrpl/ziae003
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- Publication type:
- Article
Risk of wrist fracture, estimated by the load-to-strength ratio, declines following sleeve gastrectomy in adolescents and young adults.
- Published in:
- Osteoporosis International, 2024, v. 35, n. 2, p. 285, doi. 10.1007/s00198-023-06941-1
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- Article
Changes in Vertebral Bone Density and Paraspinal Muscle Morphology Following Spaceflight and 1 Year Readaptation on Earth.
- Published in:
- JBMR Plus, 2023, v. 7, n. 12, p. 1, doi. 10.1002/jbm4.10810
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- Publication type:
- Article
Sex differences in muscle health in simulated micro- and partial-gravity environments in rats.
- Published in:
- Sports Medicine & Health Science (SMHS), 2023, v. 5, n. 4, p. 319, doi. 10.1016/j.smhs.2023.09.002
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- Publication type:
- Article
Total Calcium Intake Is Associated With Trabecular Bone Density in Adolescent Girls With Type 1 Diabetes.
- Published in:
- JBMR Plus, 2023, v. 7, n. 11, p. 1, doi. 10.1002/jbm4.10813
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- Publication type:
- Article
A two-cohort study on the association between the gut microbiota and bone density, microarchitecture, and strength.
- Published in:
- Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1237727
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- Publication type:
- Article
EMG Validation of a Subject-Specific Thoracolumbar Spine Musculoskeletal Model During Dynamic Activities in Older Adults.
- Published in:
- Annals of Biomedical Engineering, 2023, v. 51, n. 10, p. 2313, doi. 10.1007/s10439-023-03273-3
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- Publication type:
- Article
Male Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 10, p. e1063, doi. 10.1210/clinem/dgad215
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- Publication type:
- Article
Bone changes post-sleeve gastrectomy in relation to body mass and hormonal changes.
- Published in:
- European Journal of Endocrinology, 2023, v. 189, n. 3, p. 346, doi. 10.1093/ejendo/lvad121
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- Publication type:
- Article
A Fracture Risk Assessment Tool for High Resolution Peripheral Quantitative Computed Tomography.
- Published in:
- Journal of Bone & Mineral Research, 2023, v. 38, n. 9, p. 1234, doi. 10.1002/jbmr.4808
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- Publication type:
- Article
Biomechanical CT to Assess Bone After Sleeve Gastrectomy in Adolescents With Obesity: A Prospective Longitudinal Study.
- Published in:
- Journal of Bone & Mineral Research, 2023, v. 38, n. 7, p. 933, doi. 10.1002/jbmr.4784
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- Publication type:
- Article
Accumulation in Visceral Adipose Tissue Over 6 Years Is Associated With Lower Paraspinal Muscle Density.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 6, p. 1348, doi. 10.1210/clinem/dgac744
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- Publication type:
- Article
Changes in Distal Tibial Microarchitecture During Eight Weeks of U.S. Army Basic Combat Training Differ by Sex and Race.
- Published in:
- JBMR Plus, 2023, v. 7, n. 4, p. 1, doi. 10.1002/jbm4.10719
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- Publication type:
- Article
Skeletal Effects of Sleeve Gastrectomy in AContext: Vertical sleeve gastrectomy (VSG) is an increasingly common tool to achieve weight loss and improve metabolic health in adolescents and young adults with obesity, although it may adversely affect bone health. Objective: This work aimed to evaluate the effect of VSG on bone health in youth. Methods: An observational 2-year study was conducted at a tertiary care center of 66 patients aged 13 to 24 years with moderate-to-severe obesity meeting criteria for VSG. The patients underwent VSG (n= 30) or nonsurgical (n=36) management per the decision of patient and clinical team. Main outcome measures included dual-energy x-ray absorptiometry (DXA) and high-resolution peripheral quantitative computed tomography (HRpQCT) measures of bone mineral density (BMD), geometry, and microarchitecture. Results: VSG patients achieved 25.3±2.0% weight loss at 2 years (P<.001) while control subjects gained 4.0±2.0% (P= .026). Total hip BMD declined 8.5±1.0% following VSG compared with 0.1±1.0% gain in controls (P< .001), with similar results at the femoral neck (P<.001). Total volumetric BMD (vBMD) decreased both at the distal radius and tibia following VSG (P<.001) driven primarily by trabecular vBMD loss (P< .001). Two-year changes in cortical vBMD did not differ between groups, though cortical porosity decreased following VSG both at the radius and tibia (P=.048 and P< .001). Cortical thickness increased in controls but not in VSG (P=.022 and P= .002 for between-group comparisons at the radius and tibia, respectively). Following VSG, estimated failure load decreased at the radius and did not demonstrate the physiologic increases at the tibia observed in controls. Conclusion: VSG leads to progressive changes in bone health over 2 years, and may lead to increased skeletal fragility in adolescents and young adults.dolescents and Young Adults: A 2-Year Longitudinal Study.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 4, p. 847, doi. 10.1210/clinem/dgac634
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- Publication type:
- Article
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study.
- Published in:
- Calcified Tissue International, 2023, v. 112, n. 3, p. 338, doi. 10.1007/s00223-022-01047-y
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- Publication type:
- Article
The Effect of Zoledronic Acid on Bone Microarchitecture and Strength after Denosumab and Teriparatide Administration: DATA‐HD Study Extension.
- Published in:
- Journal of Bone & Mineral Research, 2023, v. 38, n. 1, p. 26, doi. 10.1002/jbmr.4737
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- Publication type:
- Article
Potential of Neuromuscular Electrical Stimulation as a Bone Loss Countermeasure in Microgravity.
- Published in:
- Aerospace Medicine & Human Performance, 2022, v. 93, n. 11, p. 774, doi. 10.3357/AMHP.6101.2022
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- Publication type:
- Article
Diabetes Mellitus and the Benefit of Antiresorptive Therapy on Fracture Risk.
- Published in:
- Journal of Bone & Mineral Research, 2022, v. 37, n. 11, p. 2121, doi. 10.1002/jbmr.4697
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- Publication type:
- Article
Sustained Morphine Delivery Suppresses Bone Formation and Alters Metabolic and Circulating miRNA Profiles in Male C57BL/6J Mice.
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- Journal of Bone & Mineral Research, 2022, v. 37, n. 11, p. 2226, doi. 10.1002/jbmr.4690
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- Publication type:
- Article
Unraveling the physiologic paradoxes that underlie exercise prescription for stress fracture prevention.
- Published in:
- Experimental Biology & Medicine, 2022, v. 247, n. 20, p. 1833, doi. 10.1177/15353702221112108
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- Article
Correction to: Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents.
- Published in:
- Biomedicines, 2022, v. 10, n. 9, p. 2187, doi. 10.3390/biomedicines10092187
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- Publication type:
- Article
Restrictive Eating and Prior Low-Energy Fractures Are Associated With History of Multiple Bone Stress Injuries.
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- International Journal of Sport Nutrition & Exercise Metabolism, 2022, v. 32, n. 5, p. 325, doi. 10.1123/ijsnem.2021-0323
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- Publication type:
- Article
Serum 25-Hydroxyvitamin D is Associated With Bone Microarchitecture and Strength in a Multiracial Cohort of Young Adults.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 9, p. e3679, doi. 10.1210/clinem/dgac388
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- Publication type:
- Article
Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 9, p. e3747, doi. 10.1210/clinem/dgac361
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- Publication type:
- Article
Insulin-like growth factor binding protein 2 null mice (Igfbp2−/−) are protected against trabecular bone loss after vertical sleeve gastrectomy.
- Published in:
- Surgical Endoscopy & Other Interventional Techniques, 2022, v. 36, n. 9, p. 6984, doi. 10.1007/s00464-022-09069-1
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- Publication type:
- Article
Impact of Low Energy Availability on Skeletal Health in Physically Active Adults.
- Published in:
- Calcified Tissue International, 2022, v. 110, n. 5, p. 605, doi. 10.1007/s00223-022-00957-1
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- Publication type:
- Article
Propranolol Promotes Bone Formation and Limits Resorption Through Novel Mechanisms During Anabolic Parathyroid Hormone Treatment in Female C57BL/6J Mice.
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- Journal of Bone & Mineral Research, 2022, v. 37, n. 5, p. 954, doi. 10.1002/jbmr.4523
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- Publication type:
- Article
Bone Microarchitecture Phenotypes Identified in Older Adults Are Associated With Different Levels of Osteoporotic Fracture Risk.
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- Journal of Bone & Mineral Research, 2022, v. 37, n. 3, p. 428, doi. 10.1002/jbmr.4494
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- Publication type:
- Article
Age‐Related Changes in Bone Density, Microarchitecture, and Strength in Postmenopausal Black and White Women: The SWAN Longitudinal HR‐pQCT Study.
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- Journal of Bone & Mineral Research, 2022, v. 37, n. 1, p. 41, doi. 10.1002/jbmr.4460
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- Publication type:
- Article
Metatarsal Bone Marrow Edema on Magnetic Resonance Imaging and Its Correlation to Bone Stress Injuries in Male Collegiate Basketball Players.
- Published in:
- Orthopaedic Journal of Sports Medicine, 2022, v. 10, n. 1, p. 1, doi. 10.1177/23259671211063505
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- Publication type:
- Article
The oestrous cycle and skeletal muscle atrophy: Investigations in rodent models of muscle loss.
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- Experimental Physiology, 2021, v. 106, n. 12, p. 2472, doi. 10.1113/EP089962
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- Article
Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26571-7
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- Publication type:
- Article
RNAseq and RNA molecular barcoding reveal differential gene expression in cortical bone following hindlimb unloading in female mice.
- Published in:
- PLoS ONE, 2021, v. 16, n. 10, p. 1, doi. 10.1371/journal.pone.0250715
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- Publication type:
- Article
Promoting Women in Academic Medicine during COVID-19 and Beyond.
- Published in:
- 2021
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- Publication type:
- letter
Incidence of Hip and Subtrochanteric/Femoral Shaft Fractures in Postmenopausal Women With Osteoporosis in the Phase 3 Long‐Term Odanacatib Fracture Trial.
- Published in:
- Journal of Bone & Mineral Research, 2021, v. 36, n. 7, p. 1225, doi. 10.1002/jbmr.4284
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- Publication type:
- Article
Effect of Transdermal Estradiol and Insulin-like Growth Factor-1 on Bone Endpoints of Young Women With Anorexia Nervosa.
- Published in:
- 2021
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- Publication type:
- journal article
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.67772
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- Publication type:
- Article
Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23649-0
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- Publication type:
- Article
TRPM8 modulates temperature regulation in a sex-dependent manner without affecting cold-induced bone loss.
- Published in:
- PLoS ONE, 2021, v. 16, n. 6, p. 1, doi. 10.1371/journal.pone.0231060
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- Publication type:
- Article
Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90010-2
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- Publication type:
- Article
Higher Hand Grip Strength Is Associated With Greater Radius Bone Size and Strength in Older Men and Women: The Framingham Osteoporosis Study.
- Published in:
- JBMR Plus, 2021, v. 5, n. 5, p. 1, doi. 10.1002/jbm4.10485
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- Publication type:
- Article
Patterns of Load‐to‐Strength Ratios Along the Spine in a Population‐Based Cohort to Evaluate the Contribution of Spinal Loading to Vertebral Fractures.
- Published in:
- Journal of Bone & Mineral Research, 2021, v. 36, n. 4, p. 704, doi. 10.1002/jbmr.4222
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- Publication type:
- Article
Inhibition of longevity regulator PAPP‐A modulates tissue homeostasis via restraint of mesenchymal stromal cells.
- Published in:
- Aging Cell, 2021, v. 20, n. 3, p. 1, doi. 10.1111/acel.13313
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- Article
The Effects of Ivacaftor on Bone Density and Microarchitecture in Children and Adults with Cystic Fibrosis.
- Published in:
- 2021
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- Publication type:
- journal article
Changes in Volumetric Bone Mineral Density Over 12 Months After a Tibial Bone Stress Injury Diagnosis: Implications for Return to Sports and Military Duty.
- Published in:
- American Journal of Sports Medicine, 2021, v. 49, n. 1, p. 226, doi. 10.1177/0363546520971782
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- Publication type:
- Article