Works by Boutillier, Anne-Laurence

Results: 30

Accelerated epigenetic aging in Huntington's disease involves polycomb repressive complex 1.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56722-z

By:

Brulé, Baptiste;
Alcalá-Vida, Rafael;
Penaud, Noémie;
Scuto, Jil;
Mounier, Coline;
Seguin, Jonathan;
Khodaverdian, Sina Vincent;
Cosquer, Brigitte;
Birmelé, Etienne;
Le Gras, Stéphanie;
Decraene, Charles;
Boutillier, Anne-Laurence;
Merienne, Karine

Publication type:

Article

Ventral midline thalamus lesion prevents persistence of new (learning-triggered) hippocampal spines, delayed neocortical spinogenesis, and spatial memory durability.

Published in:

Brain Structure & Function, 2019, v. 224, n. 4, p. 1659, doi. 10.1007/s00429-019-01865-1

By:

Klein, Marie Muguet;
Cholvin, Thibault;
Cosquer, Brigitte;
Salvadori, Aurélie;
Le Mero, Julia;
Kourouma, Lola;
Boutillier, Anne-Laurence;
Pereira de Vasconcelos, Anne;
Cassel, Jean-Christophe

Publication type:

Article

Late-Life Environmental Enrichment Induces Acetylation Events and Nuclear Factor κB-Dependent Regulations in the Hippocampus of Aged Rats Showing Improved Plasticity and Learning.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 15, p. 4351, doi. 10.1523/JNEUROSCI.3239-15.2016

By:

Neidl, Romain;
Schneider, Anne;
Bousiges, Olivier;
Majchrzak, Monique;
Barbelivien, Alexandra;
de Vasconcelos, Anne Pereira;
Dorgans, Kevin;
Doussau, Frédéric;
Loeffler, Jean-Philippe;
Cassel, Jean-Christophe;
Boutillier, Anne-Laurence

Publication type:

Article

Epigenomics dysregulation and therapeutics in neurodegeneration.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.083398

By:

Boutillier, Anne‐Laurence

Publication type:

Article

Infectious Agents as Potential Drivers of α‐Synucleinopathies.

Published in:

Movement Disorders, 2022, v. 37, n. 3, p. 464, doi. 10.1002/mds.28925

By:

Linard, Morgane;
Ravier, Alix;
Mougué, Louisa;
Grgurina, Iris;
Boutillier, Anne‐Laurence;
Foubert‐Samier, Alexandra;
Blanc, Frédéric;
Helmer, Catherine

Publication type:

Article

Pituitary Adenyl Cyclase-Activating Peptide: A Hypophysiotropic Factor That Stimulates Proopiomelanocortin Gene Transcription, and Proopio-melanocortin-Derived Peptide Secretion in Corticotropic Cells.

Published in:

Neuroendocrinology, 1994, v. 60, n. 5, p. 493, doi. 10.1159/000126786

By:

Boutillier, Anne-Laurence;
Monnier, Dominique;
Koch, Bernard;
Loeffler, Philippe

Publication type:

Article

Sodium Valproate Exerts Neuroprotective Effects In Vivo through CREB-Binding Protein-Dependent Mechanisms But Does Not Improve Survival in an Amyotrophic Lateral Sclerosis Mouse Model.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 21, p. 5535, doi. 10.1523/JNEUROSCI.1139-07.2007

By:

Rouaux, Caroline;
Panteleeva, Irina;
René, Frédérique;
de Aguilar, Jose-Luis Gonzales;
Echaniz-Laguna, Andoni;
Dupuis, Luc;
Menger, Yannick;
Boutillier, Anne-Laurence;
Loefler, Jean-Philippe

Publication type:

Article

Lesions and Genes: On the Edge of Improved Isomorphic Models for Alzheimer’s Disease?

Published in:

Neurodegenerative Diseases, 2008, v. 5, n. 5, p. 318, doi. 10.1159/000135616

By:

de Aguilar, Jose-Luis Gonzalez;
Loeffler, Jean-Philippe;
Boutillier, Anne-Laurence

Publication type:

Article

Sp3 and Sp4 Transcription Factor Levels Are Increased in Brains of Patients with Alzheimer’s Disease.

Published in:

Neurodegenerative Diseases, 2007, v. 4, n. 6, p. 413, doi. 10.1159/000107701

By:

Boutillier, Stéphanie;
Lannes, Béatrice;
Buée, Luc;
Delacourte, André;
Rouaux, Caroline;
Mohr, Michel;
Bellocq, Jean-Pierre;
Sellal, François;
Larmet, Yves;
Boutillier, Anne-Laurence;
Loeffler, Jean-Philippe

Publication type:

Article

Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway.

Published in:

European Journal of Neuroscience, 1999, v. 11, n. 2, p. 441, doi. 10.1046/j.1460-9568.1999.00451.x

By:

Boutillier, Anne‐Laurence;
Kienlen‐Campard, Pascal;
Loeffler, Jean‐Philippe

Publication type:

Article

A Novel Activator of CBP/p300 Acetyltransferases Promotes Neurogenesis and Extends Memory Duration in Adult Mice.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 26, p. 10698, doi. 10.1523/JNEUROSCI.5772-12.2013

By:

Chatterjee, Snehajyoti;
Mizar, Pushpak;
Cassel, Raphaelle;
Neidl, Romain;
Selvi, B. Ruthrotha;
Mohankrishna, Dalvoy Vasudevarao;
Vedamurthy, Bhusainahalli M.;
Schneider, Anne;
Bousiges, Olivier;
Mathis, Chantal;
Cassel, Jean-Christophe;
Eswaramoorthy, Muthusamy;
Kundu, Tapas K.;
Boutillier, Anne-Laurence

Publication type:

Article

Spatial Memory Consolidation is Associated with Induction of Several Lysine-Acetyltransferase (Histone Acetyltransferase) Expression Levels and H2B/H4 Acetylation-Dependent Transcriptional Events in the Rat Hippocampus.

Published in:

Neuropsychopharmacology, 2010, v. 35, n. 13, p. 2521, doi. 10.1038/npp.2010.117

By:

Bousiges, Olivier;
Vasconcelos, Anne Pereira de;
Neidl, Romain;
Cosquer, Brigitte;
Herbeaux, Karine;
Panteleeva, Irina;
Loeffler, Jean-Philippe;
Cassel, Jean-Christophe;
Boutillier, Anne-Laurence

Publication type:

Article

A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 5, p. 526, doi. 10.15252/emmm.201404433

By:

Palamiuc, Lavinia;
Schlagowski, Anna;
Ngo, Shyuan T;
Vernay, Aurelia;
Dirrig‐Grosch, Sylvie;
Henriques, Alexandre;
Boutillier, Anne‐Laurence;
Zoll, Joffrey;
Echaniz‐Laguna, Andoni;
Loeffler, Jean‐Philippe;
René, Frédérique

Publication type:

Article

The CBP KIX domain regulates long-term memory and circadian activity.

Published in:

BMC Biology, 2020, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12915-020-00886-1

By:

Chatterjee, Snehajyoti;
Angelakos, Christopher C.;
Bahl, Ethan;
Hawk, Joshua D.;
Gaine, Marie E.;
Poplawski, Shane G.;
Schneider-Anthony, Anne;
Yadav, Manish;
Porcari, Giulia S.;
Cassel, Jean-Christophe;
Giese, K. Peter;
Michaelson, Jacob J.;
Lyons, Lisa C.;
Boutillier, Anne-Laurence;
Abel, Ted

Publication type:

Article

PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system.

Published in:

Nature Communications, 2014, v. 5, n. 4, p. 3527, doi. 10.1038/ncomms4527

By:

Puttagunta, Radhika;
Tedeschi, Andrea;
Sória, Marilia Grando;
Hervera, Arnau;
Lindner, Ricco;
Rathore, Khizr I.;
Gaub, Perrine;
Joshi, Yashashree;
Nguyen, Tuan;
Schmandke, Antonio;
Laskowski, Claudia J.;
Boutillier, Anne-Laurence;
Bradke, Frank;
Di Giovanni, Simone

Publication type:

Article

Selective E2F-dependent gene transcription is controlled by histone deacetylase activity during neuronal apoptosis.

Published in:

Journal of Neurochemistry, 2003, v. 84, n. 4, p. 814, doi. 10.1046/j.1471-4159.2003.01581.x

By:

Boutillier, Anne-Laurence;
Trinh, Emmanuelle;
Loeffler, Jean-Philippe

Publication type:

Article

Brain-Derived Neurotrophic Factor Exerts Opposing Effects on β<sub>2</sub>-Adrenergic Receptor According to Depolarization Status of Cerebellar Neurons.

Published in:

Journal of Neurochemistry, 1999, v. 73, n. 4, p. 1467, doi. 10.1046/j.1471-4159.1999.0731467.x

By:

Gaiddon, Christian;
Larmet, Yves;
Trinh, Emmanuelle;
Boutillier, Anne-Laurence;
Sommer, Bernd;
Loeffler, Jean-Philippe

Publication type:

Article

Constitutive Repression of E2F1 Transcriptional Activity through HDAC Proteins Is Essential for Neuronal Survival.

Published in:

Annals of the New York Academy of Sciences, 2002, v. 973, n. 1, p. 438, doi. 10.1111/j.1749-6632.2002.tb04679.x

By:

BOUTILLIER, ANNE-LAURENCE;
TRINH, EMMANUELLE;
LOEFFLER, JEAN-PHILIPPE

Publication type:

Article

Hippocampal Astrocyte Morphology Follows an Unexpected Trajectory With Age in a Transgenic Rodent Model of Tauopathy.

Published in:

Glia (0894-1491), 2025, v. 73, n. 7, p. 1502, doi. 10.1002/glia.70019

By:

Augustin, Emma;
Vinasco‐Sandoval, Tatiana;
Riquelme‐Perez, Miriam;
Plassard, Damien;
Gaudin, Mylène;
Aurégan, Gwenaëlle;
Mitja, Julien;
Bernier, Sueva;
Joséphine, Charlène;
Petit, Fanny;
Jan, Caroline;
Hérard, Anne‐Sophie;
Gaillard, Marie‐Claude;
Launay, Agathe;
Faivre, Emilie;
Buée, Luc;
Boutillier, Anne‐Laurence;
Blum, David;
Bemelmans, Alexis‐Pierre;
Bonvento, Gilles

Publication type:

Article

Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.586399

By:

Wang, Xiao-Lan;
Wolff, Samantha E. C.;
Korpel, Nikita;
Milanova, Irina;
Sandu, Cristina;
Rensen, Patrick C. N.;
Kooijman, Sander;
Cassel, Jean-Christophe;
Kalsbeek, Andries;
Boutillier, Anne-Laurence;
Yi, Chun-Xia

Publication type:

Article

Caspase-dependent cleavage of the retinoblastoma protein is an early step in neuronal apoptosis.

Published in:

Oncogene, 2000, v. 19, n. 18, p. 2171, doi. 10.1038/sj.onc.1203532

By:

Boutillier, Anne-Laurence;
Trinh, Emmanuelle;
Loeffler, Jean-Philippe

Publication type:

Article

The retinoblastoma susceptibility gene product/Sp1 signalling pathway is modulated by Ca<sup>2+</sup>/calmodulin kinases II and IV activity.

Published in:

Oncogene, 1999, v. 18, n. 17, p. 2762, doi. 10.1038/sj.onc.1202634

By:

Sohm, Frédéric;
Gaiddon, Christian;
Antoine, Muriel;
Boutillier, Anne-Laurence;
Loeffler, Jean-Philippe

Publication type:

Article

Régulations épigénétiques et plasticitécérébrale : vers de nouvelles thérapies dans les maladies neurodégénératives ?

Published in:

Biologie Aujourd'hui, 2016, v. 210, n. 4, p. 297, doi. 10.1051/jbio/2017002

By:

Merienne, Karine;
Boutillier, Anne-Laurence

Publication type:

Article

Brain network remodelling reflects tau-related pathology prior to memory deficits in Thy-Tau22 mice.

Published in:

2020

By:

Degiorgis, Laetitia;
Karatas, Meltem;
Sourty, Marion;
Faivre, Emilie;
Lamy, Julien;
Noblet, Vincent;
Bienert, Thomas;
Reisert, Marco;
Elverfeldt, Dominik von;
Buée, Luc;
Blum, David;
Boutillier, Anne-Laurence;
Armspach, Jean-Paul;
Blanc, Frédéric;
Harsan, Laura-Adela;
von Elverfeldt, Dominik

Publication type:

journal article

HP1α guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation.

Published in:

EMBO Journal, 2007, v. 26, n. 15, p. 3616, doi. 10.1038/sj.emboj.7601789

By:

Panteleeva, Irina;
Boutillier, Stéphanie;
See, Violaine;
Spiller, Dave G.;
Rouaux, Caroline;
Almouzni, Geneviève;
Bailly, Delphine;
Maison, Christèle;
Lai, Helen C.;
Loeffler, Jean-Philippe;
Boutillier, Anne-Laurence

Publication type:

Article

Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington's disease mice.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20605-2

By:

Alcalá-Vida, Rafael;
Seguin, Jonathan;
Lotz, Caroline;
Molitor, Anne M.;
Irastorza-Azcarate, Ibai;
Awada, Ali;
Karasu, Nezih;
Bombardier, Aurélie;
Cosquer, Brigitte;
Skarmeta, Jose Luis Gomez;
Cassel, Jean-Christophe;
Boutillier, Anne-Laurence;
Sexton, Thomas;
Merienne, Karine

Publication type:

Article

Detection of Histone Acetylation Levels in the Dorsal Hippocampus Reveals Early Tagging on Specific Residues of H2B and H4 Histones in Response to Learning.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057816

By:

Bousiges, Olivier;
Neidl, Romain;
Majchrzak, Monique;
Muller, Marc-Antoine;
Barbelivien, Alexandra;
Pereira de Vasconcelos, Anne;
Schneider, Anne;
Loeffler, Jean-Philippe;
Cassel, Jean-Christophe;
Boutillier, Anne-Laurence

Publication type:

Article

Transcriptional Activation of the Proopiomelanocortin Gene by Cyclic AMP-responsive Element Binding Protein.

Published in:

Pituitary, 1998, v. 1, n. 1, p. 33, doi. 10.1023/A:1009966808106

By:

Boutillier, Anne-Laurence;
Gaiddon, Christian;
Lorang, Dominique;
Roberts, James;
Loeffler, Jean-Philippe

Publication type:

Article

Altered enhancer transcription underlies Huntington's disease striatal transcriptional signature.

Published in:

Scientific Reports, 2017, p. 42875, doi. 10.1038/srep42875

By:

Le Gras, Stéphanie;
Keime, Céline;
Anthony, Anne;
Lotz, Caroline;
De Longprez, Lucie;
Brouillet, Emmanuel;
Cassel, Jean-Christophe;
Boutillier, Anne-Laurence;
Merienne, Karine

Publication type:

Article

Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 12, p. 3481, doi. 10.1093/hmg/ddv099

By:

Achour, Mayada;
Le Gras, Stéphanie;
Keime, Céline;
Parmentier, Frédéric;
Lejeune, François-Xavier;
Boutillier, Anne-Laurence;
Néri, Christian;
Davidson, Irwin;
Merienne, Karine

Publication type:

Article