Works matching AU Bourinet, Emmanuel

Results: 32

A Destructive Interaction Mechanism Accounts for Dominant-Negative Effects of Misfolded Mutants of Voltage-Gated Calcium Channels.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 17, p. 4501, doi. 10.1523/JNEUROSCI.2844-07.2008

By:

Mezghrani, Alexandre;
Monteil, Arnaud;
Watschinger, Katrin;
Sinnegger-Brauns, Martina J.;
Barrère, Christian;
Bourinet, Emmanuel;
Nargeot, Joël;
Striessnig, Jörg;
Lory, Philippe

Publication type:

Article

Dissecting the functional role of different isoforms of the L-type Ca2+channel.

Published in:

Journal of Clinical Investigation, 2004, v. 113, n. 10, p. 1382, doi. 10.1172/JCI200421815

By:

Bourinet, Emmanuel;
Mangoni, Matteo E.;
Nargeot, Joël

Publication type:

Article

Novel Scorpion Toxin ω-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via Ca V 3.3 and Ca V 3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 9, p. 4745, doi. 10.3390/ijms25094745

By:

Wang, Dan;
Herzig, Volker;
Dekan, Zoltan;
Rosengren, K. Johan;
Payne, Colton D.;
Hasan, Md. Mahadhi;
Zhuang, Jiajie;
Bourinet, Emmanuel;
Ragnarsson, Lotten;
Alewood, Paul F.;
Lewis, Richard J.

Publication type:

Article

Prolonged Piezo1 Activation Induces Cardiac Arrhythmia.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6720, doi. 10.3390/ijms24076720

By:

Rolland, Laura;
Torrente, Angelo Giovanni;
Bourinet, Emmanuel;
Maskini, Dounia;
Drouard, Aurélien;
Chevalier, Philippe;
Jopling, Chris;
Faucherre, Adèle

Publication type:

Article

The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic β-cell line.

Published in:

EMBO Reports, 2009, v. 10, n. 8, p. 873, doi. 10.1038/embor.2009.125

By:

Swayne, Leigh Anne;
Mezghrani, Alexandre;
Varrault, Annie;
Chemin, Jean;
Bertrand, Gyslaine;
Dalle, Stephane;
Bourinet, Emmanuel;
Lory, Philippe;
Miller, Richard J;
Nargeot, Joel;
Monteil, Arnaud

Publication type:

Article

Specific contribution of human T-type calcium channel isotypes (α1G, α1H and α1I) to neuronal excitability.

Published in:

Journal of Physiology, 2002, v. 540, n. 1, p. 3, doi. 10.1113/jphysiol.2001.013269

By:

Chemin, Jean;
Monteil, Arnaud;
Perez-Reyes, Edward;
Bourinet, Emmanuel;
Nargeot, Joël;
Lory, Philippe

Publication type:

Article

Role of T CD4+ cells, macrophages, C‐low threshold mechanoreceptors and spinal Cav3.2 channels in inflammation and related pain‐like symptoms in murine inflammatory models.

Published in:

British Journal of Pharmacology, 2023, v. 180, n. 4, p. 385, doi. 10.1111/bph.15956

By:

Picard, Elodie;
Kerckhove, Nicolas;
François, Amaury;
Boudieu, Ludivine;
Billard, Elisabeth;
Carvalho, Frédéric Antonio;
Bogard, Gemma;
Gosset, Philippe;
Bourdier, Justine;
Aissouni, Youssef;
Bourinet, Emmanuel;
Eschalier, Alain;
Daulhac, Laurence;
Mallet, Christophe

Publication type:

Article

Inhibition of Cav 3.2 calcium channels: A new target for colonic hypersensitivity associated with low-grade inflammation.

Published in:

2019

By:

Picard, Elodie;
Carvalho, Frederic Antonio;
Agosti, Francina;
Bourinet, Emmanuel;
Ardid, Denis;
Eschalier, Alain;
Daulhac, Laurence;
Mallet, Christophe

Publication type:

journal article

Multiple determinants in voltage‐dependent P/Q calcium channels control their retention in the endoplasmic reticulum.

Published in:

European Journal of Neuroscience, 2002, v. 16, n. 5, p. 883, doi. 10.1046/j.1460-9568.2002.02168.x

By:

Cornet, Véronique;
Bichet, Delphine;
Sandoz, Guillaume;
Marty, Isabelle;
Brocard, Jacques;
Bourinet, Emmanuel;
Mori, Yasuo;
Villaz, Michel;
De Waard, Michel

Publication type:

Article

Alleviating Pain Hypersensitivity through Activation of Type 4 Metabotropic Glutamate Receptor.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 48, p. 18951, doi. 10.1523/JNEUROSCI.1221-13.2013

By:

Vilar, Bruno;
Busserolles, Jérôme;
Ling, Bing;
Laffray, Sophie;
Ulmann, Lauriane;
Malhaire, Fanny;
Chapuy, Eric;
Aissouni, Youssef;
Etienne, Monique;
Bourinet, Emmanuel;
Acher, Francine;
Pin, Jean-Philippe;
Eschalier, Alain;
Goudet, Cyril

Publication type:

Article

T-Type Calcium Channel Inhibition Underlies the Analgesic Effects of the Endogenous Lipoamino Acids.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 42, p. 13106, doi. 10.1523/JNEUROSCI.2919-09.2009

By:

Barbara, Guillaume;
Alloui, Abdelkrim;
Nargeot, Joël;
Lory, Philippe;
Eschalier, Alain;
Bourinet, Emmanuel;
Chemin, Jean

Publication type:

Article

Stable Membrane Expression of Postsynaptic CaV1.2 Calcium Channel Clusters Is Independent of Interactions with AKAP79/150 and PDZ Proteins.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 51, p. 13845, doi. 10.1523/JNEUROSCI.3213-08.2008

By:

Di Biase, Valentina;
Obermair, Gerald J.;
Szabo, Zsolt;
Altier, Christophe;
Sanguesa, Juan;
Bourinet, Emmanuel;
Flucher, Bernhard E.

Publication type:

Article

Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39703-3

By:

Candelas, Miriam;
Reynders, Ana;
Arango-Lievano, Margarita;
Neumayer, Christoph;
Fruquière, Antoine;
Demes, Elsa;
Hamid, Jawed;
Lemmers, Céline;
Bernat, Claire;
Monteil, Arnaud;
Compan, Vincent;
Laffray, Sophie;
Inquimbert, Perrine;
Le Feuvre, Yves;
Zamponi, Gerald W.;
Moqrich, Aziz;
Bourinet, Emmanuel;
Méry, Pierre-François

Publication type:

Article

Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors.

Published in:

EMBO Molecular Medicine, 2011, v. 3, n. 5, p. 266, doi. 10.1002/emmm.201100134

By:

Descoeur, Juliette;
Pereira, Vanessa;
Pizzoccaro, Anne;
Francois, Amaury;
Ling, Bing;
Maffre, Violette;
Couette, Brigitte;
Busserolles, Jérôme;
Courteix, Christine;
Noel, Jacques;
Lazdunski, Michel;
Eschalier, Alain;
Authier, Nicolas;
Bourinet, Emmanuel

Publication type:

Article

T-type calcium channels in chronic pain: mouse models and specific blockers.

Published in:

Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 4, p. 707, doi. 10.1007/s00424-014-1484-4

By:

François, Amaury;
Laffray, Sophie;
Pizzoccaro, Anne;
Eschalier, Alain;
Bourinet, Emmanuel

Publication type:

Article

Voltage-gated calcium channels in chronic pain: emerging role of alternative splicing.

Published in:

Pflügers Archiv: European Journal of Physiology, 2008, v. 456, n. 3, p. 459, doi. 10.1007/s00424-007-0390-4

By:

Swayne, Leigh Anne;
Bourinet, Emmanuel

Publication type:

Article

Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit.

Published in:

Nature, 1997, v. 385, n. 6615, p. 442, doi. 10.1038/385442a0

By:

Zamponi, Gerald W.;
Bourinet, Emmanuel

Publication type:

Article

Genetic alteration of the metal/redox modulation of Cav3.2 T-type calcium channel reveals its role in neuronal excitability.

Published in:

Journal of Physiology, 2016, v. 594, n. 13, p. 3561, doi. 10.1113/JP271925

By:

Voisin, Tiphaine;
Bourinet, Emmanuel;
Lory, Philippe

Publication type:

Article

Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.

Published in:

EMBO Journal, 2005, v. 24, n. 2, p. 315, doi. 10.1038/sj.emboj.7600515

By:

Bourinet, Emmanuel;
Alloui, Abdelkrim;
Monteil, Arnaud;
Barrère, Christian;
Couette, Brigitte;
Poirot, Olivier;
Pages, Anne;
McRory, John;
Snutch, Terrance P.;
Eschalier, Alain;
Nargeot, Joël

Publication type:

Article

Centrally expressed Cav3.2 T- type calcium channel is critical for the initiation and maintenance of neuropathic pain.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.79018

By:

Fayad, Sophie L.;
Ourties, Guillaume;
Le Gac, Benjamin;
Jouffre, Baptiste;
Lamoine, Sylvain;
Fruquière, Antoine;
Laffray, Sophie;
Gasmi, Laila;
Cauli, Bruno;
Mallet, Christophe;
Bourinet, Emmanuel;
Bessaih, Thomas;
Lambert, Régis C.;
Leresche, Nathalie

Publication type:

Article

ORL1 receptor–mediated internalization of N-type calcium channels.

Published in:

Nature Neuroscience, 2006, v. 9, n. 1, p. 31, doi. 10.1038/nn1605

By:

Altier, Christophe;
Khosravani, Houman;
Evans, Rhian M.;
Hameed, Shahid;
Peloquin, Jean B.;
Vartian, Brian A.;
Chen, Lina;
Beedle, Aaron M.;
Ferguson, Stephen S. G.;
Mezghrani, Alexandre;
Dubel, Stefan J.;
Bourinet, Emmanuel;
McRory, John E.;
Zamponi, Gerald W.

Publication type:

Article

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

Published in:

Nature Neuroscience, 2004, v. 7, n. 2, p. 118, doi. 10.1038/nn1180

By:

Beedle, Aaron M;
Mcrory, John E;
Poirot, Olivier;
Doering, Clinton J;
Altier, Christophe;
Barrere, Christian;
Hamid, Jawed;
Nargeot, Joel;
Bourinet, Emmanuel;
Zamponi, Gerald W

Publication type:

Article

Splicing of α1A subunit gene generates phenotypic variants of P- and Q-type calcium channels.

Published in:

Nature Neuroscience, 1999, v. 2, n. 5, p. 407, doi. 10.1038/8070

By:

Bourinet, Emmanuel;
Soong, Tuck W.;
Sutton, Kathy;
Slaymaker, Sarah;
Mathews, Eleanor;
Monteil, Arnaud;
Zamponi, Gerald W.;
Nargeot, Joel;
Snutch, Terry P.

Publication type:

Article

Evaluation of the Spider (Phlogiellus genus) Phlotoxin 1 and Synthetic Variants as Antinociceptive Drug Candidates.

Published in:

Toxins, 2019, v. 11, n. 9, p. 484, doi. 10.3390/toxins11090484

By:

Gonçalves, Tânia C.;
Lesport, Pierre;
Kuylle, Sarah;
Stura, Enrico;
Ciolek, Justyna;
Mourier, Gilles;
Servent, Denis;
Bourinet, Emmanuel;
Benoit, Evelyne;
Gilles, Nicolas

Publication type:

Article

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.

Published in:

Toxins, 2017, v. 9, n. 7, p. 227, doi. 10.3390/toxins9070227

By:

Song, Ok-Ryul;
Han-Byul Kim;
Jouny, Samuel;
Ricard, Isabelle;
Vandeputte, Alexandre;
Deboosere, Nathalie;
Marion, Estelle;
Queval, Christophe J.;
Lesport, Pierre;
Bourinet, Emmanuel;
Henrion, Daniel;
Seog Bae Oh;
Lebon, Guillaume;
Sandoz, Guillaume;
Yeramian, Edouard;
Marsollier, Laurent;
Brodin, Priscille

Publication type:

Article

TRPV1 promotes opioid analgesia during inflammation.

Published in:

Science Signaling, 2019, v. 12, n. 575, p. N.PAG, doi. 10.1126/scisignal.aav0711

By:

Basso, Lilian;
Aboushousha, Reem;
Iftinca, Mircea;
Melo, Helvira;
Flynn, Robyn;
Hollenberg, Morley D.;
Altier, Christophe;
Fan, Churmy Yong;
Thompson, Roger;
Trang, Tuan;
Agosti, Francina;
Bourinet, Emmanuel

Publication type:

Article

Epigenetics Involvement in Oxaliplatin-Induced Potassium Channel Transcriptional Downregulation and Hypersensitivity.

Published in:

Molecular Neurobiology, 2021, v. 58, n. 7, p. 3575, doi. 10.1007/s12035-021-02361-6

By:

Pereira, Vanessa;
Lamoine, Sylvain;
Cuménal, Mélissa;
Lolignier, Stéphane;
Aissouni, Youssef;
Pizzoccaro, Anne;
Prival, Laetitia;
Balayssac, David;
Eschalier, Alain;
Bourinet, Emmanuel;
Busserolles, Jérôme

Publication type:

Article

Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain.

Published in:

Scientific Reports, 2016, p. 36407, doi. 10.1038/srep36407

By:

Ventéo, Stéphanie;
Laffray, Sophie;
Wetzel, Christiane;
Rivat, Cyril;
Scamps, Frédérique;
Méchaly, Ilana;
Bauchet, Luc;
Raoul, Cédric;
Bourinet, Emmanuel;
Lewin, Gary R.;
Carroll, Patrick;
Pattyn, Alexandre

Publication type:

Article

The Low-Threshold Calcium Channel Cav3.2 Mediates Burst Firing of Mature Dentate Granule Cells.

Published in:

Cerebral Cortex, 2018, v. 28, n. 7, p. 2594, doi. 10.1093/cercor/bhy084

By:

Dumenieu, Mael;
Senkov, Oleg;
Mironov, Andrey;
Bourinet, Emmanuel;
Kreutz, Michael R.;
Dityatev, Alexander;
Heine, Martin;
Bikbaev, Arthur;
Lopez-Rojas, Jeffrey

Publication type:

Article

Differential targeting of the L-type Ca2+ channel α1C (CaV1.2) to synaptic and extrasynaptic compartments in hippocampal neurons.

Published in:

European Journal of Neuroscience, 2004, v. 19, n. 8, p. 2109, doi. 10.1111/j.0953-816X.2004.03272.x

By:

Obermair, Gerald J.;
Szabo, Zsolt;
Bourinet, Emmanuel;
Flucher, Bernhard E.

Publication type:

Article

AKAP79 modulation of L-type channels involves disruption of intramolecular interactions in the CaV1.2 subunit.

Published in:

Channels (19336950), 2012, v. 6, n. 3, p. 157, doi. 10.4161/chan.20865

By:

Altier, Christophe;
Dubel, Stefan J.;
Barrere, Christian;
Jarvis, Scott E.;
Stotz, Stephanie C.;
Scott, John D.;
Nargeot, Joel;
Zamponi, Gerald W.;
Bourinet, Emmanuel

Publication type:

Article

Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNaV1.7 and hCaV3 voltage‐gated channels.

Published in:

FEBS Journal, 2023, v. 290, n. 14, p. 3688, doi. 10.1111/febs.16773

By:

Giribaldi, Julien;
Chemin, Jean;
Tuifua, Marie;
Deuis, Jennifer R.;
Mary, Rosanna;
Vetter, Irina;
Wilson, David T.;
Daly, Norelle L.;
Schroeder, Christina I.;
Bourinet, Emmanuel;
Dutertre, Sébastien

Publication type:

Article

Works matching AU Bourinet, Emmanuel

A Destructive Interaction Mechanism Accounts for Dominant-Negative Effects of Misfolded Mutants of Voltage-Gated Calcium Channels.

Dissecting the functional role of different isoforms of the L-type Ca<sup>2+</sup>channel.

Novel Scorpion Toxin ω-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via Ca V 3.3 and Ca V 3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain.

Prolonged Piezo1 Activation Induces Cardiac Arrhythmia.

The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic β-cell line.

Specific contribution of human T-type calcium channel isotypes (α<sub>1G</sub>, α<sub>1H</sub> and α<sub>1I</sub>) to neuronal excitability.

Role of T CD4<sup>+</sup> cells, macrophages, C‐low threshold mechanoreceptors and spinal Ca<sub>v</sub>3.2 channels in inflammation and related pain‐like symptoms in murine inflammatory models.

Inhibition of Ca<sub>v</sub> 3.2 calcium channels: A new target for colonic hypersensitivity associated with low-grade inflammation.

Multiple determinants in voltage‐dependent P/Q calcium channels control their retention in the endoplasmic reticulum.

Alleviating Pain Hypersensitivity through Activation of Type 4 Metabotropic Glutamate Receptor.

T-Type Calcium Channel Inhibition Underlies the Analgesic Effects of the Endogenous Lipoamino Acids.

Stable Membrane Expression of Postsynaptic Ca<sub>V</sub>1.2 Calcium Channel Clusters Is Independent of Interactions with AKAP79/150 and PDZ Proteins.

Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons.

Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors.

T-type calcium channels in chronic pain: mouse models and specific blockers.

Voltage-gated calcium channels in chronic pain: emerging role of alternative splicing.

Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit.

Genetic alteration of the metal/redox modulation of Cav3.2 T-type calcium channel reveals its role in neuronal excitability.

Silencing of the Ca<sub>v</sub>3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.

Centrally expressed Cav3.2 T- type calcium channel is critical for the initiation and maintenance of neuropathic pain.

ORL1 receptor–mediated internalization of N-type calcium channels.

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

Splicing of α<sub>1A</sub> subunit gene generates phenotypic variants of P- and Q-type calcium channels.

Evaluation of the Spider (Phlogiellus genus) Phlotoxin 1 and Synthetic Variants as Antinociceptive Drug Candidates.

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.

TRPV1 promotes opioid analgesia during inflammation.

Epigenetics Involvement in Oxaliplatin-Induced Potassium Channel Transcriptional Downregulation and Hypersensitivity.

Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain.

The Low-Threshold Calcium Channel Cav3.2 Mediates Burst Firing of Mature Dentate Granule Cells.

Differential targeting of the L-type Ca<sup>2+</sup> channel α<sub>1C</sub> (Ca<sub>V</sub>1.2) to synaptic and extrasynaptic compartments in hippocampal neurons.

AKAP79 modulation of L-type channels involves disruption of intramolecular interactions in the Ca<sub>V</sub>1.2 subunit.

Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNa<sub>V</sub>1.7 and hCa<sub>V</sub>3 voltage‐gated channels.