Works matching AU Bouitbir, Jamal

Results: 43

Implication of Lipids in Calcified Aortic Valve Pathogenesis: Why Did Statins Fail?

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 12, p. 3331, doi. 10.3390/jcm11123331

By:

Nsaibia, Mohamed J.;
Devendran, Anichavezhi;
Goubaa, Eshak;
Bouitbir, Jamal;
Capoulade, Romain;
Bouchareb, Rihab

Publication type:

Article

Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00367

By:

Paech, Franziska;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Effect of l-carnitine supplementation on the body carnitine pool, skeletal muscle energy metabolism and physical performance in male vegetarians.

Published in:

European Journal of Nutrition, 2016, v. 55, n. 1, p. 207, doi. 10.1007/s00394-015-0838-9

By:

Novakova, Katerina;
Kummer, Oliver;
Bouitbir, Jamal;
Stoffel, Sonja;
Hoerler-Koerner, Ulrike;
Bodmer, Michael;
Roberts, Paul;
Urwyler, Albert;
Ehrsam, Rolf;
Krähenbühl, Stephan

Publication type:

Article

Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice.

Published in:

European Journal of Nutrition, 2014, v. 53, n. 6, p. 1313, doi. 10.1007/s00394-013-0631-6

By:

Morand, Réjane;
Bouitbir, Jamal;
Felser, Andrea;
Hench, Jürgen;
Handschin, Christoph;
Frank, Stephan;
Krähenbühl, Stephan

Publication type:

Article

Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a ‘mitohormesis’ mechanism involving reactive oxygen species and PGC-1.

Published in:

European Heart Journal, 2012, v. 33, n. 11, p. 1397, doi. 10.1093/eurheartj/ehr224

By:

Bouitbir, Jamal;
Charles, Anne-Laure;
Echaniz-Laguna, Andoni;
Kindo, Michel;
Daussin, Frédéric;
Auwerx, Johan;
Piquard, François;
Geny, Bernard;
Zoll, Joffrey

Publication type:

Article

Skeletal muscle mitochondrial dysfunction precedes right ventricular impairment in experimental pulmonary hypertension.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 373, n. 1/2, p. 161, doi. 10.1007/s11010-012-1485-6

By:

Enache, Irina;
Charles, Anne-Laure;
Bouitbir, Jamal;
Favret, Fabrice;
Zoll, Joffrey;
Metzger, Daniel;
Oswald-Mammosser, Monique;
Geny, Bernard;
Charloux, Anne

Publication type:

Article

PGC-1β modulates statin-associated myotoxicity in mice.

Published in:

Archives of Toxicology, 2019, v. 93, n. 2, p. 487, doi. 10.1007/s00204-018-2369-7

By:

Singh, François;
Zoll, Joffrey;
Duthaler, Urs;
Charles, Anne-Laure;
Panajatovic, Miljenko V.;
Laverny, Gilles;
McWilliams, Thomas G.;
Metzger, Daniel;
Geny, Bernard;
Krähenbühl, Stephan;
Bouitbir, Jamal

Publication type:

Article

Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression.

Published in:

Biomedicines, 2020, v. 8, n. 9, p. 351, doi. 10.3390/biomedicines8090351

By:

Panajatovic, Miljenko Valentin;
Singh, François;
Krähenbühl, Stephan;
Bouitbir, Jamal

Publication type:

Article

Reactive Metamizole Metabolites Enhance the Toxicity of Hemin on the ATP Pool in HL60 Cells by Inhibition of Glycolysis.

Published in:

Biomedicines, 2020, v. 8, n. 7, p. 212, doi. 10.3390/biomedicines8070212

By:

Rudin, Deborah;
Schmutz, Maurice;
Roos, Noëmi Johanna;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 965, doi. 10.3390/cells9040965

By:

Zhou, Xun;
Bouitbir, Jamal;
Liechti, Matthias E.;
Krähenbühl, Stephan;
Mancuso, Riccardo V.

Publication type:

Article

PGC‐1α plays a pivotal role in simvastatin‐induced exercise impairment in mice.

Published in:

Acta Physiologica, 2020, v. 228, n. 4, p. 1, doi. 10.1111/apha.13402

By:

Panajatovic, Miljenko Valentin;
Singh, François;
Roos, Noëmi Johanna;
Duthaler, Urs;
Handschin, Christoph;
Krähenbühl, Stephan;
Bouitbir, Jamal

Publication type:

Article

Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples.

Published in:

Metabolites (2218-1989), 2020, v. 10, n. 7, p. 282, doi. 10.3390/metabo10070282

By:

Gómez, Cristina;
Stücheli, Simon;
Kratschmar, Denise V.;
Bouitbir, Jamal;
Odermatt, Alex

Publication type:

Article

Muscles Susceptibility to Ischemia-Reperfusion Injuries Depends on Fiber Type Specific Antioxidant Level.

Published in:

Frontiers in Physiology, 2017, v. 8, p. 1, doi. 10.3389/fphys.2017.00052

By:

Charles, Anne-Laure;
Guilbert, Anne-Sophie;
Guillot, Max;
Talha, Samy;
Lejay, Anne;
Meyer, Alain;
Kindo, Michel;
Wolff, Valérie;
Bouitbir, Jamal;
Zoll, Joffrey;
Geny, Bernard

Publication type:

Article

Left Ventricular Transmural Gradient in Mitochondrial Respiration Is Associated with Increased Sub-Endocardium Nitric Oxide and Reactive Oxygen Species Productions.

Published in:

Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00331

By:

Kindo, Michel;
Gerelli, Sébastien;
Bouitbir, Jamal;
Tam Hoang Minh;
Charles, Anne-Laure;
Mazzucotelli, Jean-Philippe;
Zoll, Joffrey;
Piquard, François;
Geny, Bernard

Publication type:

Article

Impaired Exercise Performance and Skeletal Muscle Mitochondrial Function in Rats with Secondary Carnitine Deficiency.

Published in:

Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00345

By:

Bouitbir, Jamal;
Haegler, Patrizia;
Singh, François;
Joerin, Lorenz;
Felser, Andrea;
Duthaler, Urs;
Krähenbühl, Stephan

Publication type:

Article

Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection.

Published in:

Drug Design, Development & Therapy, 2015, v. 9, p. 3589, doi. 10.2147/DDDT.S81891

By:

Zoll, Joffrey;
Bouitbir, Jamal;
Sirvent, Pascal;
Klein, Alexis;
Charton, Antoine;
Jimenez, Liliana;
Péronnet, François R.;
Geny, Bernard;
Richard, Ruddy

Publication type:

Article

Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0171026

By:

Haegler, Patrizia;
Grünig, David;
Berger, Benjamin;
Terracciano, Luigi;
Krähenbühl, Stephan;
Bouitbir, Jamal

Publication type:

Article

PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12304, doi. 10.3390/ijms232012304

By:

Novakova, Katerina;
Török, Michael;
Panajatovic, Miljenko;
Bouitbir, Jamal;
Duong, François H. T.;
Handschin, Christoph;
Krähenbühl, Stephan

Publication type:

Article

Mitochondrial Toxicity Associated with Imatinib and Sorafenib in Isolated Rat Heart Fibers and the Cardiomyoblast H9c2 Cell Line.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2282, doi. 10.3390/ijms23042282

By:

Bouitbir, Jamal;
Panajatovic, Miljenko V.;
Krähenbühl, Stephan

Publication type:

Article

Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4950, doi. 10.3390/ijms22094950

By:

Panajatovic, Miljenko V.;
Singh, Francois;
Krähenbühl, Stephan;
Bouitbir, Jamal;
Villani, Gaetano

Publication type:

Article

Para-Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 8, p. 2841, doi. 10.3390/ijms21082841

By:

Zhou, Xun;
Bouitbir, Jamal;
Liechti, Matthias E.;
Krähenbühl, Stephan;
Mancuso, Riccardo V.

Publication type:

Article

Exogenous Iron Increases Fasciocidal Activity and Hepatocellular Toxicity of the Synthetic Endoperoxides OZ78 and MT04.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4880, doi. 10.3390/ijms20194880

By:

Brecht, Karin;
Kirchhofer, Carla;
Bouitbir, Jamal;
Trapani, Francesca;
Keiser, Jennifer;
Krähenbühl, Stephan

Publication type:

Article

Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1561, doi. 10.3390/ijms20071561

By:

Zhou, Xun;
Luethi, Dino;
Sanvee, Gerda M.;
Bouitbir, Jamal;
Liechti, Matthias E.;
Krähenbühl, Stephan

Publication type:

Article

Imatinib and Dasatinib Provoke Mitochondrial Dysfunction Leading to Oxidative Stress in C2C12 Myotubes and Human RD Cells.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.01106

By:

Bouitbir, Jamal;
Panajatovic, Miljenko Valentin;
Frechard, Theo;
Roos, Noëmi Johanna;
Krähenbühl, Stephan

Publication type:

Article

Lapatinib Activates the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in HepG2 Cells.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00944

By:

Roos, Noëmi Johanna;
Aliu, Diell;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Insulin prevents and reverts simvastatin-induced toxicity in C2C12 skeletal muscle cells.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43938-5

By:

Sanvee, Gerda M.;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Effect of chronic pre-treatment with angiotensin converting enzyme inhibition on skeletal muscle mitochondrial recovery after ischemia/reperfusion.

Published in:

Fundamental & Clinical Pharmacology, 2010, v. 24, n. 3, p. 333, doi. 10.1111/j.1472-8206.2009.00763.x

By:

Thaveau, Fabien;
Zoll, Joffrey;
Bouitbir, Jamal;
N'Guessan, Benoît;
Plobner, Philippe;
Chakfe, Nabil;
Kretz, Jean-Georges;
Richard, Ruddy;
Piquard, François;
Geny, Bernard

Publication type:

Article

Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.620635

By:

Blaser, Lea S;
Duthaler, Urs;
Bouitbir, Jamal;
Leuppi-Taegtmeyer, Anne B;
Liakoni, Evangelia;
Dolf, Reto;
Mayr, Michael;
Drewe, Jürgen;
Krähenbühl, Stephan;
Haschke, Manuel

Publication type:

Article

Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel PhenotypingCocktail Differently.

Published in:

Clinical Pharmacokinetics, 2022, v. 61, n. 7, p. 1039, doi. 10.1007/s40262-022-01119-0

By:

Duthaler, Urs;
Bachmann, Fabio;
Suenderhauf, Claudia;
Grandinetti, Tanja;
Pfefferkorn, Florian;
Haschke, Manuel;
Hruz, Petr;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress.

Published in:

Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00332

By:

Kindo, Michel;
Gerelli, Sébastien;
Bouitbir, Jamal;
Charles, Anne-Laure;
Zoll, Joffrey;
Hoang Minh, Tam;
Monassier, Laurent;
Favret, Fabrice;
Piquard, François;
Geny, Bernard

Publication type:

Article

Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress.

Published in:

Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00332

By:

Kindo, Michel;
Gerelli, Sebastien;
Bouitbir, Jamal;
Charles, Anne-Laure;
Zoll, Joffrey;
Minh, Tam Hoang;
Monassier, Laurent;
Favret, Fabrice;
Piquard, Francois;
Geny, Bernard

Publication type:

Article

IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes.

Published in:

Archives of Toxicology, 2017, v. 91, n. 5, p. 2223, doi. 10.1007/s00204-016-1871-z

By:

Bonifacio, Annalisa;
Sanvee, Gerda;
Brecht, Karin;
Kratschmar, Denise;
Odermatt, Alex;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo.

Published in:

Archives of Toxicology, 2016, v. 90, n. 1, p. 203, doi. 10.1007/s00204-014-1378-4

By:

Bonifacio, Annalisa;
Mullen, Peter;
Mityko, Ileana;
Navegantes, Luiz;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Effect of the Catechol-O-Methyltransferase Inhibitors Tolcapone and Entacapone on Fatty Acid Metabolism in HepaRG Cells.

Published in:

Toxicological Sciences, 2018, v. 164, n. 2, p. 477, doi. 10.1093/toxsci/kfy101

By:

Grünig, David;
Felser, Andrea;
Duthaler, Urs;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents.

Published in:

Toxicological Sciences, 2017, v. 157, n. 1, p. 183, doi. 10.1093/toxsci/kfx029

By:

Haegler, Patrizia;
Joerin, Lorenz;
Krähenbühl, Stephan;
Bouitbir, Jamal

Publication type:

Article

Mechanisms of Hepatocellular Toxicity Associated with Dronedarone—A Comparison to Amiodarone.

Published in:

Toxicological Sciences, 2013, v. 131, n. 2, p. 480, doi. 10.1093/toxsci/kfs298

By:

Felser, Andrea;
Blum, Kim;
Lindinger, Peter W.;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Age Modulates Fe3O4 Nanoparticles Liver Toxicity: Dose-Dependent Decrease in Mitochondrial Respiratory Chain Complexes Activities and Coupling in Middle-Aged as Compared to Young Rats.

Published in:

2014

By:

Baratli, Yosra;
Charles, Anne-Laure;
Wolff, Valérie;
Ben Tahar, Lotfi;
Smiri, Leila;
Bouitbir, Jamal;
Zoll, Joffrey;
Sakly, Mohsen;
Auger, Cyril;
Vogel, Thomas;
Abdelmelek, Hafedh;
Tebourbi, Olfa;
Geny, Bernard

Publication type:

Journal Article

Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines.

Published in:

Journal of Applied Toxicology, 2018, v. 38, n. 3, p. 418, doi. 10.1002/jat.3551

By:

Mingard, Cécile;
Paech, Franziska;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Hepatotoxicity Due to Azole Antimycotic Agents in a HLA B*35:02-Positive Patient.

Published in:

Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00645

By:

Bühler, Tim;
Medinger, Michael;
Bouitbir, Jamal;
Krähenbühl, Stephan;
Leuppi-Taegtmeyer, Anne

Publication type:

Article

Integration of High-Throughput Imaging and Multiparametric Metabolic Profiling Reveals a Mitochondrial Mechanism of Tenofovir Toxicity.

Published in:

Function, 2023, v. 4, n. 1, p. 1, doi. 10.1093/function/zqac065

By:

Pearson, Adam;
Haenni, Dominik;
Bouitbir, Jamal;
Hunt, Matthew;
Payne, Brendan A I;
Sachdeva, Ashwin;
Hung, Rachel K Y;
Post, Frank A;
Connolly, John;
Nlandu-Khodo, Stellor;
Jankovic, Nevena;
Bugarski, Milica;
Hall, Andrew M

Publication type:

Article

Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?

Published in:

Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00579

By:

Pottecher, Julien;
Adamopoulos, Chris;
Lejay, Anne;
Bouitbir, Jamal;
Charles, Anne-Laure;
Meyer, Alain;
Singer, Mervyn;
Wolff, Valerie;
Diemunsch, Pierre;
Laverny, Gilles;
Metzger, Daniel;
Geny, Bernard

Publication type:

Article

Effect of eccentric versus concentric exercise training on mitochondrial function.

Published in:

Muscle & Nerve, 2014, v. 50, n. 5, p. 803, doi. 10.1002/mus.24215

By:

Isner‐Horobeti, Marie‐Eve;
Rasseneur, Laurence;
Lonsdorfer‐Wolf, Evelyne;
Dufour, Stéphane Pascal;
Doutreleau, Stéphane;
Bouitbir, Jamal;
Zoll, Joffrey;
Kapchinsky, Sophia;
Geny, Bernard;
Daussin, Frédéric Nicolas;
Burelle, Yan;
Richard, Ruddy

Publication type:

Article

Mitochondria of trained skeletal muscle are protected from deleterious effects of statins.

Published in:

Muscle & Nerve, 2012, v. 46, n. 3, p. 367, doi. 10.1002/mus.23309

By:

Bouitbir, Jamal;
Daussin, Frédéric;
Charles, Anne-Laure;
Rasseneur, Laurence;
Dufour, Stéphane;
Richard, Ruddy;
Piquard, François;
Geny, Bernard;
Zoll, Joffrey

Publication type:

Article