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Evaluation of Homogentisic Acid, a Prospective Antibacterial Agent Highlighted by the Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2) Clinical Trial.
- Published in:
- Cells (2073-4409), 2023, v. 12, n. 13, p. 1683, doi. 10.3390/cells12131683
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- Publication type:
- Article
Laminin N‐terminus α31 expression during development is lethal and causes widespread tissue‐specific defects in a transgenic mouse model.
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- FASEB Journal, 2022, v. 36, n. 7, p. 1, doi. 10.1096/fj.202002588RRR
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- Publication type:
- Article
Syndecan‐3 enhances anabolic bone formation through WNT signaling.
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- FASEB Journal, 2021, v. 35, n. 4, p. 1, doi. 10.1096/fj.202002024R
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- Publication type:
- Article
Generation of a mouse line harboring a bi-transgene expressing luciferase and tamoxifen-activatable creER<sup>T2</sup> recombinase in cartilage.
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- Genesis: The Journal of Genetics & Development, 2014, v. 52, n. 2, p. n/a, doi. 10.1002/dvg.22734
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- Publication type:
- Article
Wound-associated macrophages control collagen 1α2 transcription during the early stages of skin wound healing.
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- Experimental Dermatology, 2013, v. 22, n. 2, p. 143, doi. 10.1111/exd.12068
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- Publication type:
- Article
The anterior cruciate ligament in murine post-traumatic osteoarthritis: markers and mechanics.
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- Arthritis Research & Therapy, 2022, v. 24, n. 1, p. 1, doi. 10.1186/s13075-022-02798-7
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- Publication type:
- Article
Hyperglycemia causes renal cell damage via CCN2-induced activation of the TrkA receptor: implications for diabetic nephropathy.
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- 2012
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- Publication type:
- journal article
Hyperglycemia Causes Renal Cell Damage via CCN2-Induced Activation of the TrkA Receptor.
- Published in:
- Diabetes, 2012, v. 61, n. 9, p. 2280, doi. 10.2337/db11-1138
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- Publication type:
- Article
Targeting Dysregulation of Metalloproteinase Activity in Osteoarthritis.
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- Calcified Tissue International, 2021, v. 109, n. 3, p. 277, doi. 10.1007/s00223-020-00739-7
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- Publication type:
- Article
Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces.
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- Calcified Tissue International, 2021, v. 108, n. 2, p. 207, doi. 10.1007/s00223-020-00764-6
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- Publication type:
- Article
Altered Bone Mechanics, Architecture and Composition in the Skeleton of TIMP-3-Deficient Mice.
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- 2017
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- Publication type:
- journal article
Regulation of programmed-death ligand in the human head and neck squamous cell carcinoma microenvironment is mediated through matrix metalloproteinase-mediated proteolytic cleavage.
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- International Journal of Oncology, 2018, v. 52, n. 2, p. 379, doi. 10.3892/ijo.2017.4221
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- Publication type:
- Article
Regulation of PD-L1 expression in a high-grade invasive human oral squamous cell carcinoma microenvironment.
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- International Journal of Oncology, 2017, v. 50, n. 1, p. 41, doi. 10.3892/ijo.2016.3785
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- Publication type:
- Article
Extra-cellular matrix in vascular networks.
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- Cell Proliferation, 2004, v. 37, n. 3, p. 207, doi. 10.1111/j.1365-2184.2004.00306.x
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- Publication type:
- Article
Hereditary Tyrosinemia Type 1 Mice under Continuous Nitisinone Treatment Display Remnants of an Uncorrected Liver Disease Phenotype.
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- Genes, 2023, v. 14, n. 3, p. 693, doi. 10.3390/genes14030693
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- Publication type:
- Article
MiR-18a-5p Targets Connective Tissue Growth Factor Expression and Inhibits Transforming Growth Factor β2-Induced Trabecular Meshwork Cell Contractility.
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- Genes, 2022, v. 13, n. 8, p. 1500, doi. 10.3390/genes13081500
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- Publication type:
- Article
Fibroblast Matrix Gene Expression and Connective Tissue Remodeling: Role of Endothelin-1.
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- Journal of Investigative Dermatology, 2001, v. 116, n. 3, p. 417, doi. 10.1046/j.1523-1747.2001.01256.x
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- Publication type:
- Article
Microchimeric Fetal Cells Are Recruited to Maternal Kidney following Injury and Activate Collagen Type I Transcription.
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- Cells Tissues Organs, 2011, v. 193, n. 6, p. 379, doi. 10.1159/000321172
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- Publication type:
- Article
788. Antisense Therapy for Duchenne Muscular Dystrophy: A Realistic Possibility
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- 2005
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- Publication type:
- Abstract
Targeted Inhibition of Aggrecanases Prevents Articular Cartilage Degradation and Augments Bone Mass in the STR/Ort Mouse Model of Spontaneous Osteoarthritis.
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- Arthritis & Rheumatology, 2019, v. 71, n. 4, p. 571, doi. 10.1002/art.40765
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- Publication type:
- Article
Failed Degradation of JunB Contributes to Overproduction of Type I Collagen and Development of Dermal Fibrosis in Patients With Systemic Sclerosis.
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- Arthritis & Rheumatology, 2015, v. 67, n. 1, p. 243, doi. 10.1002/art.38897
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- Publication type:
- Article
In Vivo Imaging of Matrix Metalloproteinase 12 and Matrix Metalloproteinase 13 Activities in the Mouse Model of Collagen-Induced Arthritis.
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- Arthritis & Rheumatology, 2014, v. 66, n. 3, p. 589, doi. 10.1002/art.38295
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- Publication type:
- Article
Selectively high efficacy of eribulin against high-grade invasive recurrent and/or metastatic squamous cell carcinoma of the head and neck.
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- Oncology Letters, 2019, v. 17, n. 6, p. 5064
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- Publication type:
- Article
Fetal stem cell microchimerism: natural-born healers or killers?
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- Molecular Human Reproduction, 2010, v. 16, n. 11, p. 869, doi. 10.1093/molehr/gaq067
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- Publication type:
- Article
Venous identity requires BMP signalling through ALK3.
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- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08315-w
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- Publication type:
- Article
Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease.
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- Respiratory Research, 2013, v. 14, n. 8, p. 1, doi. 10.1186/1465-9921-14-80
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- Publication type:
- Article
Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease.
- Published in:
- 2013
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- Publication type:
- journal article
Gene expression profiling reveals novel TGFβ targets in adult lung fibroblasts.
- Published in:
- Respiratory Research, 2004, v. 5, p. 24, doi. 10.1186/1465-9921-5-24
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- Publication type:
- Article
Metalloelastase-12 is involved in the temporomandibular joint inflammatory response as well as cartilage degradation by aggrecanases in STR/Ort mice.
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- Biomedical Reports, 2021, v. 14, n. 6, p. N.PAG
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- Publication type:
- Article
Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-66233-0
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- Publication type:
- Article
Heat Shock Protein B1-Deficient Mice Display Impaired Wound Healing.
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- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077383
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- Publication type:
- Article
Distant Mesenchymal Progenitors Contribute to Skin Wound Healing and Produce Collagen: Evidence from a Murine Fetal Microchimerism Model
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062662
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- Publication type:
- Article
Ontological Differences in First Compared to Third Trimester Human Fetal Placental Chorionic Stem Cells.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0043395
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- Publication type:
- Article
Biphasic recruitment of microchimeric fetal mesenchymal cells in fibrosis following acute kidney injury.
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- Kidney International, 2014, v. 85, n. 3, p. 600, doi. 10.1038/ki.2013.459
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- Publication type:
- Article
Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis.
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- Arthritis Research & Therapy, 2020, v. 22, n. 1, p. 1, doi. 10.1186/s13075-020-02261-5
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- Publication type:
- Article
Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria.
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- Journal of Inherited Metabolic Disease, 2020, v. 43, n. 2, p. 259, doi. 10.1002/jimd.12172
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- Article
Expression of semaphorin‐3A in the joint and role in osteoarthritis.
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- Cell Biochemistry & Function, 2024, v. 42, n. 3, p. 1, doi. 10.1002/cbf.4012
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- Publication type:
- Article
Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity.
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- PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167971
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- Publication type:
- Article
Increased prevalence of Parkinson's disease in alkaptonuria.
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- Journal of Inherited Metabolic Disease Reports, 2023, v. 64, n. 4, p. 282, doi. 10.1002/jmd2.12367
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- Publication type:
- Article
First decade anniversary of the United Kingdom National Alkaptonuria Centre.
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- Journal of Inherited Metabolic Disease Reports, 2023, v. 64, n. 2, p. 212, doi. 10.1002/jmd2.12340
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- Publication type:
- Article
Expression of tyrosine pathway enzymes in mice demonstrates that homogentisate 1,2‐dioxygenase deficiency in the liver is responsible for homogentisic acid‐derived ochronotic pigmentation.
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- Journal of Inherited Metabolic Disease Reports, 2021, v. 58, n. 1, p. 52, doi. 10.1002/jmd2.12184
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- Publication type:
- Article
SIRT1 directly activates autophagy in human chondrocytes.
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- Cell Death Discovery, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41420-020-0277-0
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- Publication type:
- Article
JunB mediates enhancer/promoter activity of COL1A2 following TGF-β induction.
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- Nucleic Acids Research, 2009, v. 37, n. 16, p. 5378, doi. 10.1093/nar/gkp544
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- Publication type:
- Article
The activation of resting lymphocytes is accompanied by the biogenesis of lysosomal organelles.
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- European Journal of Immunology, 1990, v. 20, n. 10, p. 2161, doi. 10.1002/eji.1830201003
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- Publication type:
- Article
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse.
- Published in:
- Nature Medicine, 2003, v. 9, n. 8, p. 1009, doi. 10.1038/nm897
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- Publication type:
- Article
Differential Contribution of Dermal Resident and Bone Marrow-Derived Cells to Collagen Production during Wound Healing and Fibrogenesis in Mice.
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- Journal of Investigative Dermatology, 2011, v. 131, n. 2, p. 529, doi. 10.1038/jid.2010.314
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- Publication type:
- Article
Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria.
- Published in:
- Metabolites (2218-1989), 2022, v. 12, n. 10, p. 927, doi. 10.3390/metabo12100927
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- Publication type:
- Article
Revisiting Quantification of Phenylalanine/Tyrosine Flux in the Ochronotic Pathway during Long-Term Nitisinone Treatment of Alkaptonuria.
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- Metabolites (2218-1989), 2022, v. 12, n. 10, p. 920, doi. 10.3390/metabo12100920
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- Publication type:
- Article
Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment.
- Published in:
- Metabolites (2218-1989), 2022, v. 12, n. 8, p. 772, doi. 10.3390/metabo12080772
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- Publication type:
- Article
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.
- Published in:
- Human Molecular Genetics, 2019, v. 28, n. 23, p. 3928, doi. 10.1093/hmg/ddz234
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- Publication type:
- Article