Works matching AU Botton, Thomas

Results: 13

Discovery of a new molecule inducing melanoma cell death: dual AMPK/MELK targeting for novel melanoma therapies.

Published in:

Cell Death & Disease, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41419-020-03344-6

By:

Jaune, Emilie;
Cavazza, Elisa;
Ronco, Cyril;
Grytsai, Oleksandr;
Abbe, Patricia;
Tekaya, Nedra;
Zerhouni, Marwa;
Beranger, Guillaume;
Kaminski, Lisa;
Bost, Frédéric;
Gesson, Maeva;
Tulic, Meri;
Hofman, Paul;
Ballotti, Robert;
Passeron, Thierry;
Botton, Thomas;
Benhida, Rachid;
Rocchi, Stéphane

Publication type:

Article

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.

Published in:

Nature Genetics, 2015, v. 47, n. 10, p. 1194, doi. 10.1038/ng.3382

By:

Garrido, Maria;
Botton, Thomas;
Talevich, Eric;
Yeh, Iwei;
Wang, Nicholas J;
Kakavand, Hojabr;
Mann, Graham J;
Thompson, John F;
Olshen, Adam B;
Gagnon, Alexander;
Gray, Joe W;
Scolyer, Richard A;
Murali, Rajmohan;
Bastian, Boris C;
Sanborn, J Zachary;
Chung, Jongsuk;
Huh, Nam;
Wiesner, Thomas;
Shain, A Hunter;
Roy, Ritu

Publication type:

Article

Rac1 Dynamics in the Human Opportunistic Fungal Pathogen Candida albicans.

Published in:

PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0015400

By:

Vauchelles, Romain;
Danièle Stalder;
Botton, Thomas;
Arkowitz, Robert A.;
Bassilana, Martine

Publication type:

Article

Vitiligo auto‐immune response upon oxidative stress‐related mitochondrial DNA release opens up new therapeutic strategies.

Published in:

Clinical & Translational Medicine, 2024, v. 14, n. 8, p. 1, doi. 10.1002/ctm2.1810

By:

Sant'Anna‐Silva, Ana C. B.;
Botton, Thomas;
Rossi, Andrea;
Dobner, Jochen;
Bzioueche, Hanene;
Thach, Nguyen;
Blot, Lauriane;
Pagnotta, Sophie;
Kleszczynski, Konrad;
Steinbrink, Kerstin;
Mazure, Nathalie M.;
Rocchi, Stéphane;
Krutmann, Jean;
Passeron, Thierry;
Tulic, Meri K.

Publication type:

Article

CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004873

By:

Talevich, Eric;
Shain, A. Hunter;
Botton, Thomas;
Bastian, Boris C.

Publication type:

Article

Hybrid Capture‐Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1‐Mutant Cholangiocarcinoma Harboring a Novel YWHAZ‐BRAF Fusion.

Published in:

Oncologist, 2018, v. 23, n. 9, p. 998, doi. 10.1634/theoncologist.2017-0645

By:

Lim, Huat C.;
Montesion, Meagan;
Botton, Thomas;
Collisson, Eric A.;
Umetsu, Sarah E.;
Behr, Spencer C.;
Gordan, John D.;
Stephens, Phil J.;
Kelley, Robin K.

Publication type:

Article

In Vitro and In Vivo Anti-Melanoma Effects of Ciglitazone.

Published in:

Journal of Investigative Dermatology, 2009, v. 129, n. 5, p. 1208, doi. 10.1038/jid.2008.346

By:

Botton, Thomas;
Puissant, Alexandre;
Bahadoran, Philippe;
Annicotte, Jean-Sebastien;
Fajas, Lluis;
Ortonne, J-P;
Gozzerino, Genevieve;
Zamoum, Thamilla;
Tartare-Deckert, Sophie;
Bertolotto, Corine;
Ballotti, Robert;
Rocchi, Stephane

Publication type:

Article

Activating MET kinase rearrangements in melanoma and Spitz tumours.

Published in:

Nature Communications, 2015, v. 6, n. 5, p. 7174, doi. 10.1038/ncomms8174

By:

Yeh, Iwei;
Botton, Thomas;
Talevich, Eric;
Shain, A. Hunter;
Sparatta, Alyssa J.;
de la Fouchardiere, Arnaud;
Mully, Thaddeus W.;
North, Jeffrey P.;
Garrido, Maria C.;
Gagnon, Alexander;
Vemula, Swapna S.;
McCalmont, Timothy H.;
LeBoit, Philip E.;
Bastian, Boris C.

Publication type:

Article

Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.

Published in:

Nature Communications, 2014, v. 5, n. 1, p. 3116, doi. 10.1038/ncomms4116

By:

Wiesner, Thomas;
He, Jie;
Yelensky, Roman;
Esteve-Puig, Rosaura;
Botton, Thomas;
Yeh, Iwei;
Lipson, Doron;
Otto, Geoff;
Brennan, Kristina;
Murali, Rajmohan;
Garrido, Maria;
Miller, Vincent A.;
Ross, Jeffrey S.;
Berger, Michael F.;
Sparatta, Alyssa;
Palmedo, Gabriele;
Cerroni, Lorenzo;
Busam, Klaus J.;
Kutzner, Heinz;
Cronin, Maureen T.

Publication type:

Article

Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion.

Published in:

Pigment Cell & Melanoma Research, 2015, v. 28, n. 5, p. 607, doi. 10.1111/pcmr.12388

By:

Menzies, Alexander M.;
Yeh, Iwei;
Botton, Thomas;
Bastian, Boris C.;
Scolyer, Richard A.;
Long, Georgina V.

Publication type:

Article

Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy.

Published in:

Pigment Cell & Melanoma Research, 2013, v. 26, n. 6, p. 845, doi. 10.1111/pcmr.12148

By:

Botton, Thomas;
Yeh, Iwei;
Nelson, Tyrrell;
Vemula, Swapna S.;
Sparatta, Alyssa;
Garrido, Maria C.;
Allegra, Maryline;
Rocchi, Stephane;
Bahadoran, Philippe;
McCalmont, Timothy H.;
LeBoit, Philip E.;
Burton, Elizabeth A.;
Bollag, Gideon;
Ballotti, Robert;
Bastian, Boris C.

Publication type:

Article

NTRK3 kinase fusions in Spitz tumours.

Published in:

Journal of Pathology, 2016, v. 240, n. 3, p. 282, doi. 10.1002/path.4775

By:

Yeh, Iwei;
Tee, Meng Kian;
Botton, Thomas;
Shain, A Hunter;
Sparatta, Alyssa J;
Gagnon, Alexander;
Vemula, Swapna S;
Garrido, Maria C;
Nakamaru, Kenji;
Isoyama, Takeshi;
McCalmont, Timothy H;
LeBoit, Philip E;
Bastian, Boris C

Publication type:

Article

Design, Synthesis and Biological Evaluation of Novel Anticancer Amidinourea Analogues via Unexpected 1,3,5‐Triazin‐2‐one Ring Opening.

Published in:

ChemMedChem, 2024, v. 19, n. 3, p. 1, doi. 10.1002/cmdc.202300493

By:

Grytsai, Oleksandr;
Hamouda‐Tekaya, Nedra;
Botton, Thomas;
Rocchi, Stéphane;
Benhida, Rachid;
Ronco, Cyril

Publication type:

Article