Works matching AU Bottelbergs, Astrid

Results: 22

Inflammasome signaling is dispensable for ß-amyloidinduced neuropathology in preclinical models of Alzheimer's disease.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1323409

By:

Srinivasan, Sahana;
Kancheva, Daliya;
De Ren, Sofie;
Takashi Saito;
Jans, Maude;
Boone, Fleur;
Vandendriessche, Charysse;
Paesmans, Ine;
Maurin, Hervé;
Vandenbroucke, Roosmarijn E.;
Hoste, Esther;
Voet, Sofie;
Scheyltjens, Isabelle;
Pavie, Benjamin;
Lippens, Saskia;
Schwabenland, Marius;
Prinz, Marco;
Takaomi Saido;
Bottelbergs, Astrid;
Movahedi, Kiavash

Publication type:

Article

Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease.

Published in:

Journal of Nuclear Medicine, 2017, v. 58, n. 12, p. 1977, doi. 10.2967/jnumed.116.187625

By:

Deleye, Steven;
Waldron, Ann-Marie;
Verhaeghe, Jeroen;
Bottelbergs, Astrid;
Wyffels, Leonie;
Van Broeck, Bianca;
Langlois, Xavier;
Schmidt, Mark;
Stroobants, Sigrid;
Staelens, Steven

Publication type:

Article

Comparison of New Tau PET-Tracer Candidates With [<sup>18</sup>F]T808 and [<sup>18</sup>F]T807.

Published in:

Molecular Imaging, 2016, v. 15, p. 1, doi. 10.1177/1536012115624920

By:

Declercq, Lieven;
Celen, Sofie;
Lecina, Joan;
Ahamed, Muneer;
Tousseyn, Thomas;
Moechars, Diederik;
Alcazar, Jesus;
Ariza, Manuela;
Fierens, Katleen;
Bottelbergs, Astrid;
Mariën, Jonas;
Vandenberghe, Rik;
Andres, Ignacio Jose;
Van Laere, Koen;
Verbruggen, Alfons;
Bormans, Guy

Publication type:

Article

NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1459134

By:

Paesmans, Ine;
Van Kolen, Kristof;
Vandermeeren, Marc;
Shih, Pei-Yu;
Wuyts, Dirk;
Boone, Fleur;
Sanchez, Sergio Garcia;
Grauwen, Karolien;
Van Hauwermeiren, Filip;
Van Opdenbosch, Nina;
Lamkanfi, Mohamed;
van Loo, Geert;
Bottelbergs, Astrid

Publication type:

Article

NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1459134

By:

Paesmans, Ine;
Van Kolen, Kristof;
Vandermeeren, Marc;
Pei-Yu Shih;
Wuyts, Dirk;
Boone, Fleur;
Sanchez, Sergio Garcia;
Grauwen, Karolien;
Van Hauwermeiren, Filip;
Van Opdenbosch, Nina;
Lamkanfi, Mohamed;
van Loo, Geert;
Bottelbergs, Astrid

Publication type:

Article

NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1459134

By:

Paesmans, Ine;
Van Kolen, Kristof;
Vandermeeren, Marc;
Pei-Yu Shih;
Wuyts, Dirk;
Boone, Fleur;
Sanchez, Sergio Garcia;
Grauwen, Karolien;
Van Hauwermeiren, Filip;
Van Opdenbosch, Nina;
Lamkanfi, Mohamed;
van Loo, Geert;
Bottelbergs, Astrid

Publication type:

Article

Absence of Functional Peroxisomes from Mouse CNS Causes Dysmyelination and Axon Degeneration.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 15, p. 4015, doi. 10.1523/JNEUROSCI.4968-07.2008

By:

Hulshagen, Leen;
Krysko, Olga;
Bottelbergs, Astrid;
Huyghe, Steven;
Klein, Rüdiger;
Van Veldhoven, Paul P.;
De Deyn, Peter P.;
D'Hooge, Rudi;
Hartmann, Dieter;
Baes, Myriam

Publication type:

Article

Systemic immune‐checkpoint blockade with anti‐PD1 antibodies does not alter cerebral amyloid‐β burden in several amyloid transgenic mouse models.

Published in:

Glia (0894-1491), 2018, v. 66, n. 3, p. 492, doi. 10.1002/glia.23260

By:

Latta‐Mahieu, Martine;
Elmer, Bradford;
Bretteville, Alexis;
Wang, Yaming;
Lopez‐Grancha, Mati;
Goniot, Philippe;
Moindrot, Nicolas;
Ferrari, Paul;
Blanc, Véronique;
Schussler, Nathalie;
Brault, Emmanuel;
Roudières, Valérie;
Blanchard, Véronique;
Yang, Zhi‐Yong;
Barneoud, Pascal;
Bertrand, Philippe;
Roucourt, Bart;
Carmans, Sofie;
Bottelbergs, Astrid;
Mertens, Liesbeth

Publication type:

Article

Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes.

Published in:

Glia (0894-1491), 2010, v. 58, n. 13, p. 1532, doi. 10.1002/glia.21027

By:

Bottelbergs, Astrid;
Verheijden, Simon;
Hulshagen, Leen;
Gutmann, David H.;
Goebbels, Sandra;
Nave, Klaus-Armin;
Kassmann, Celia;
Baes, Myriam

Publication type:

Article

Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system.

Published in:

Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 61, doi. 10.1186/1742-2094-9-61

By:

Bottelbergs, Astrid;
Verheijden, Simon;
Van Veldhoven, Paul P.;
Just, Wilhelm;
Devos, Rita;
Baes, Myriam

Publication type:

Article

SliceMap: an algorithm for automated brain region annotation.

Published in:

Bioinformatics, 2018, v. 34, n. 4, p. 718, doi. 10.1093/bioinformatics/btx658

By:

Barbier, Michaël;
Bottelbergs, Astrid;
Nuydens, Rony;
Ebneth, Andreas;
Vos, Winnok H De

Publication type:

Article

Structural basis for the oligomerization-facilitated NLRP3 activation.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45396-8

By:

Yu, Xiaodi;
Matico, Rosalie E.;
Miller, Robyn;
Chauhan, Dhruv;
Van Schoubroeck, Bertrand;
Grauwen, Karolien;
Suarez, Javier;
Pietrak, Beth;
Haloi, Nandan;
Yin, Yanting;
Tresadern, Gary John;
Perez-Benito, Laura;
Lindahl, Erik;
Bottelbergs, Astrid;
Oehlrich, Daniel;
Van Opdenbosch, Nina;
Sharma, Sujata

Publication type:

Article

Ectopic recombination in the central and peripheral nervous system by aP2/FABP4-Cre mice: Implications for metabolism research

Published in:

FEBS Letters, 2010, v. 584, n. 5, p. 1054, doi. 10.1016/j.febslet.2010.01.061

By:

Martens, Katrin;
Bottelbergs, Astrid;
Baes, Myriam

Publication type:

Article

The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model.

Published in:

Glia (0894-1491), 2022, v. 70, n. 6, p. 1117, doi. 10.1002/glia.24160

By:

Stancu, Ilie Cosmin;
Lodder, Chritica;
Botella Lucena, Pablo;
Vanherle, Sarah;
Gutiérrez de Ravé, Manuel;
Terwel, Dick;
Bottelbergs, Astrid;
Dewachter, Ilse

Publication type:

Article

CSF p-tau increase in response to Aβ-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles.

Published in:

Acta Neuropathologica, 2022, v. 143, n. 2, p. 287, doi. 10.1007/s00401-021-02400-5

By:

Kaeser, Stephan A.;
Häsler, Lisa M.;
Lambert, Marius;
Bergmann, Carina;
Bottelbergs, Astrid;
Theunis, Clara;
Mercken, Marc;
Jucker, Mathias

Publication type:

Article

CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01204-8

By:

Lodder, Chritica;
Scheyltjens, Isabelle;
Stancu, Ilie Cosmin;
Botella Lucena, Pablo;
Gutiérrez de Ravé, Manuel;
Vanherle, Sarah;
Vanmierlo, Tim;
Cremers, Niels;
Vanrusselt, Hannah;
Brône, Bert;
Hanseeuw, Bernard;
Octave, Jean-Noël;
Bottelbergs, Astrid;
Movahedi, Kiavash;
Dewachter, Ilse

Publication type:

Article

Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology.

Published in:

Alzheimer's Research & Therapy, 2018, v. 10, p. 1, doi. 10.1186/s13195-017-0329-8

By:

Praet, Jelle;
Manyakov, Nikolay V.;
Muchene, Leacky;
Mai, Zhenhua;
Terzopoulos, Vasilis;
de Backer, Steve;
Torremans, An;
Guns, Pieter-Jan;
Van De Casteele, Tom;
Bottelbergs, Astrid;
Van Broeck, Bianca;
Sijbers, Jan;
Smeets, Dirk;
Shkedy, Ziv;
Bijnens, Luc;
Pemberton, Darrel J.;
Schmidt, Mark E.;
Van der Linden, Annemie;
Verhoye, Marleen

Publication type:

Article

PRE-CLINICAL CHARACTERIZATION OF THE NOVEL TAU PET LIGAND [18F]-JNJ'067.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1069, doi. 10.1016/j.jalz.2017.06.1531

By:

Kolb, Hartmuth C.;
Bottelbergs, Astrid;
Moechars, Diederik;
Declercq, Lieven;
Bormans, Guy;
Rombouts, Frederik

Publication type:

Article

[18F]THK-5117-PET AND [11C]PIB-PET IMAGING IN IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH) IN RELATION TO CONFIRMED AMYLOID-β PLAQUES AND TAU IN BRAIN BIOPSIES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1537, doi. 10.1016/j.jalz.2017.07.672

By:

Leinonen, Ville;
Rauramaa, Tuomas;
Bottelbergs, Astrid;
Tesseur, Ina;
Van Der Ark, Peter;
Pemberton, Darrel;
Koivisto, Anne M.;
Jääskeläinen, Juha E.;
Hiltunen, Mikko;
Johansson, Jarkko;
Jokinen, Pekka;
Rokka, Johanna;
Haaparanta-Solin, Merja;
Solin, Olof;
Okamura, Nobuyuki;
Kolb, Hartmuth C.;
Rinne, Juha O.

Publication type:

Article

IMMUNOHISTOCHEMICAL CHARACTERISATION OF NOVEL TAU ANTIBODIES IN TRANSGENIC ANIMALS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P963, doi. 10.1016/j.jalz.2017.06.1292

By:

Bottelbergs, Astrid;
Van Kolen, Kristof;
Wintmolders, Cindy;
Mercken, Marc

Publication type:

Article

In vivo molecular neuroimaging of glucose utilization and its association with fibrillar amyloid-β load in aged APPPS1-21 mice.

Published in:

Alzheimer's Research & Therapy, 2015, v. 7, p. 1, doi. 10.1186/s13195-015-0158-6

By:

Waldron, Ann-Marie;
Wintmolders, Cindy;
Bottelbergs, Astrid;
Kelley, Jonathan B.;
Schmidt, Mark E.;
Stroobants, Sigrid;
Langlois, Xavier;
Staelens, Steven

Publication type:

Article

Direct nose to brain delivery of small molecules: critical analysis of data from a standardized in vivo screening model in rats.

Published in:

Drug Delivery, 2020, v. 27, n. 1, p. 1597, doi. 10.1080/10717544.2020.1837291

By:

Dhuyvetter, Deborah;
Tekle, Fetene;
Nazarov, Maxim;
Vreeken, Rob J.;
Borghys, Herman;
Rombouts, Frederik;
Lenaerts, Ilse;
Bottelbergs, Astrid

Publication type:

Article