Works by Botta, Lorenzo

Results: 40
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    Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d ]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme.

    Published in:
    Pharmaceutics, 2023, v. 15, n. 2, p. 453, doi. 10.3390/pharmaceutics15020453
    By:
    • Poggialini, Federica;
    • Vagaggini, Chiara;
    • Brai, Annalaura;
    • Pasqualini, Claudia;
    • Crespan, Emmanuele;
    • Maga, Giovanni;
    • Perini, Cecilia;
    • Cabella, Noemi;
    • Botta, Lorenzo;
    • Musumeci, Francesca;
    • Frosini, Maria;
    • Schenone, Silvia;
    • Dreassi, Elena
    Publication type:
    Article
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    SRC Tyrosine Kinase Inhibitor and X-rays Combined Effect on Glioblastoma Cell Lines.

    Published in:
    International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 3917, doi. 10.3390/ijms21113917
    By:
    • Torrisi, Filippo;
    • Minafra, Luigi;
    • Cammarata, Francesco P.;
    • Savoca, Gaetano;
    • Calvaruso, Marco;
    • Vicario, Nunzio;
    • Maccari, Laura;
    • Pérès, Elodie A.;
    • Özçelik, Hayriye;
    • Bernaudin, Myriam;
    • Botta, Lorenzo;
    • Russo, Giorgio;
    • Parenti, Rosalba;
    • Valable, Samuel
    Publication type:
    Article
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    Novel broad spectrum virucidal molecules against enveloped viruses.

    Published in:
    PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208333
    By:
    • Civra, Andrea;
    • Lembo, David;
    • Cagno, Valeria;
    • Tapparel, Caroline;
    • Tintori, Cristina;
    • Tiberi, Marika;
    • Botta, Lorenzo;
    • Poli, Giulio;
    • Brai, Annalaura;
    • Botta, Maurizio;
    • Cavalli, Roberta
    Publication type:
    Article
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    Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation.

    Published in:
    ChemMedChem, 2011, v. 6, n. 8, p. 1371, doi. 10.1002/cmdc.201100166
    By:
    • Maga, Giovanni;
    • Falchi, Federico;
    • Radi, Marco;
    • Botta, Lorenzo;
    • Casaluce, Gianni;
    • Bernardini, Martina;
    • Irannejad, Hamid;
    • Manetti, Fabrizio;
    • Garbelli, Anna;
    • Samuele, Alberta;
    • Zanoli, Samantha;
    • Esté, José A.;
    • Gonzalez, Emmanuel;
    • Zucca, Elisa;
    • Paolucci, Stefania;
    • Baldanti, Fausto;
    • De Rijck, Jan;
    • Debyser, Zeger;
    • Botta, Maurizio
    Publication type:
    Article
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    Tyrosine Kinase Inhibitor Si409 Has In Vitro and In Vivo Anti-Tumor Activity Against Diffuse Large B-Cell Lymphoma.

    Published in:
    Pharmaceutical Chemistry Journal, 2023, v. 56, n. 12, p. 1616, doi. 10.1007/s11094-023-02836-x
    By:
    • Rango, Enrico;
    • Di Maria, Salvatore;
    • Zamperini, Claudio;
    • Poggialini, Federica;
    • Crespan, Emmanuele;
    • Perini, Cecilia;
    • Sabetta, Samantha;
    • Saponara, Simona;
    • Fusi, Fabio;
    • Maga, Giovanni;
    • Angelucci, Adriano;
    • Gaudio, Eugenio;
    • Berton, Francesco;
    • Schenone, Silvia;
    • Botta, Lorenzo;
    • Dreassi, Elena;
    • Botta, Maurizio
    Publication type:
    Article
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    Targeting DDX3X Helicase Activity with BA103 Shows Promising Therapeutic Effects in Preclinical Glioblastoma Models.

    Published in:
    Cancers, 2021, v. 13, n. 21, p. 5569, doi. 10.3390/cancers13215569
    By:
    • Brai, Annalaura;
    • Riva, Valentina;
    • Clementi, Letizia;
    • Falsitta, Lucia;
    • Zamperini, Claudio;
    • Sinigiani, Virginia;
    • Festuccia, Claudio;
    • Sabetta, Samantha;
    • Aiello, Davide;
    • Roselli, Camilla;
    • Garbelli, Anna;
    • Trivisani, Claudia Immacolata;
    • Maccari, Laura;
    • Bugli, Francesca;
    • Sanguinetti, Maurizio;
    • Calandro, Pierpaolo;
    • Chiariello, Mario;
    • Quaranta, Paola;
    • Botta, Lorenzo;
    • Angelucci, Adriano
    Publication type:
    Article
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    Focused library of phenyl-fused macrocyclic amidinoureas as antifungal agents.

    Published in:
    Molecular Diversity, 2022, v. 26, n. 6, p. 3399, doi. 10.1007/s11030-022-10388-7
    By:
    • Balestri, Lorenzo J. I.;
    • D'Agostino, Ilaria;
    • Rango, Enrico;
    • Vagaggini, Chiara;
    • Marchitiello, Rosalba;
    • Mariotti, Melinda;
    • Casian, Alexandru;
    • Deodato, Davide;
    • Truglio, Giuseppina I.;
    • Orofino, Francesco;
    • Sanguinetti, Maurizio;
    • Bugli, Francesca;
    • Botta, Lorenzo;
    • Dreassi, Elena
    Publication type:
    Article
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    Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X.

    Published in:
    Molecules, 2019, v. 24, n. 21, p. 3988, doi. 10.3390/molecules24213988
    By:
    • Brai, Annalaura;
    • Ronzini, Stefania;
    • Riva, Valentina;
    • Botta, Lorenzo;
    • Zamperini, Claudio;
    • Borgini, Matteo;
    • Trivisani, Claudia Immacolata;
    • Garbelli, Anna;
    • Pennisi, Carla;
    • Boccuto, Adele;
    • Saladini, Francesco;
    • Zazzi, Maurizio;
    • Maga, Giovanni;
    • Botta, Maurizio
    Publication type:
    Article
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    SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation.

    Published in:
    Cellular Physiology & Biochemistry (Karger AG), 2015, v. 35, n. 5, p. 2006, doi. 10.1159/000374008
    By:
    • D''antona, Lucia;
    • amato, Rosario;
    • Talarico, Cristina;
    • Ortuso, Francesco;
    • Menniti, Miranda;
    • Dattilo, Vincenzo;
    • Iuliano, Rodolfo;
    • Gigliotti, Francesco;
    • artese, anna;
    • Costa, Giosuè;
    • Schenone, Silvia;
    • Musumeci, Francesca;
    • abbruzzese, Claudia;
    • Botta, Lorenzo;
    • Trapasso, Francesco;
    • alcaro, Stefano;
    • Paggi, Marco G.;
    • Perrotti, Nicola
    Publication type:
    Article
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