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Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97.
Published in:
Communications Chemistry, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42004-022-00782-5
By:
- Bothe, Sebastian;
- Hänzelmann, Petra;
- Böhler, Stephan;
- Kehrein, Josef;
- Zehe, Markus;
- Wiedemann, Christoph;
- Hellmich, Ute A.;
- Brenk, Ruth;
- Schindelin, Hermann;
- Sotriffer, Christoph
Publication type:
Article
7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.93094
By:
- Brenner, Marian;
- Zink, Christoph;
- Witzinger, Linda;
- Keller, Angelika;
- Hadamek, Kerstin;
- Bothe, Sebastian;
- Neuenschwander, Martin;
- Villmann, Carmen;
- von Kries, Jens Peter;
- Schindelin, Hermann;
- Jeanclos, Elisabeth;
- Gohla, Antje
Publication type:
Article
Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development.
Published in:
PLoS Pathogens, 2020, v. 16, n. 6, p. 1, doi. 10.1371/journal.ppat.1008640
By:
- Green, Judith L.;
- Wu, Yang;
- Encheva, Vesela;
- Lasonder, Edwin;
- Prommaban, Adchara;
- Kunzelmann, Simone;
- Christodoulou, Evangelos;
- Grainger, Munira;
- Truongvan, Ngoc;
- Bothe, Sebastian;
- Sharma, Vikram;
- Song, Wei;
- Pinzuti, Irene;
- Uthaipibull, Chairat;
- Srichairatanakool, Somdet;
- Birault, Veronique;
- Langsley, Gordon;
- Schindelin, Hermann;
- Stieglitz, Benjamin;
- Snijders, Ambrosius P.
Publication type:
Article

Found: 3

Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97.

7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase.

Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development.