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Transfection of glycoprotein encoding mRNA for swift evaluation of N‐glycan engineering strategies.
- Published in:
- Biotechnology Progress, 2020, v. 36, n. 4, p. 1, doi. 10.1002/btpr.2990
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- Publication type:
- Article
Process parameter shifting: Part I. Effect of DOT, pH, and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled batch bioreactors.
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- Biotechnology & Bioengineering, 2006, v. 94, n. 6, p. 1033, doi. 10.1002/bit.21013
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- Article
Process parameter shifting: Part II. Biphasic cultivation-A tool for enhancing the volumetric productivity of batch processes using Epo-Fc expressing CHO cells.
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- Biotechnology & Bioengineering, 2006, v. 94, n. 6, p. 1045, doi. 10.1002/bit.20958
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- Article
Screening for improved cell performance: Selection of subclones with altered production kinetics or improved stability by cell sorting.
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- Biotechnology & Bioengineering, 2004, v. 88, n. 6, p. 699, doi. 10.1002/bit.20271
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- Article
Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris.
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- Biotechnology & Bioengineering, 2004, v. 85, n. 4, p. 367, doi. 10.1002/bit.10904
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- Article
Optimization of recombinant protein expression level in Escherichia coli by flow cytometry and cell sorting.
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- Biotechnology & Bioengineering, 2002, v. 80, n. 1, p. 93, doi. 10.1002/bit.10353
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- Publication type:
- Article
Efficient selection of high-producing subclones during gene amplification of recombinant Chinese hamster ovary cells by flow cytometry and cell sorting.
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- Biotechnology & Bioengineering, 2002, v. 77, n. 1, p. 118, doi. 10.1002/bit.10186
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- Publication type:
- Article
Efficient selection of high-producing subclones during gene amplification of recombinant Chinese hamster ovary cells by flow cytometry and cell sorting.
- Published in:
- Biotechnology & Bioengineering, 2000, v. 71, n. 4, p. 266, doi. 10.1002/1097-0290(2000)71:4<266::AID-BIT1016>3.0.CO;2-2
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- Article
Construction of a Public CHO Cell Line Transcript Database Using Versatile Bioinformatics Analysis Pipelines.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085568
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- Article
Functional Interaction between Type III-Secreted Protein IncA of Chlamydophila psittaci and Human G3BP1.
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- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016692
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- Article
Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures.
- Published in:
- Biotechnology Journal, 2012, v. 7, n. 4, p. 500, doi. 10.1002/biot.201100143
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- Article
CHO-K1 host cells adapted to growth in glutamine-free medium by FACS-assisted evolution.
- Published in:
- Biotechnology Journal, 2010, v. 5, n. 10, p. 1090, doi. 10.1002/biot.201000095
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- Article
Nanopore Cas9‐targeted sequencing enables accurate and simultaneous identification of transgene integration sites, their structure and epigenetic status in recombinant Chinese hamster ovary cells.
- Published in:
- Biotechnology & Bioengineering, 2023, v. 120, n. 9, p. 2403, doi. 10.1002/bit.28382
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- Publication type:
- Article
SLAM‐seq reveals early transcriptomic response mechanisms upon glutamine deprivation in Chinese hamster ovary cells.
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- Biotechnology & Bioengineering, 2023, v. 120, n. 4, p. 970, doi. 10.1002/bit.28320
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- Article
Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities.
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- Biotechnology & Bioengineering, 2020, v. 117, n. 11, p. 3435, doi. 10.1002/bit.27493
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- Article
Genetic engineering approaches to improve posttranslational modification of biopharmaceuticals in different production platforms.
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- Biotechnology & Bioengineering, 2019, v. 116, n. 10, p. 2778, doi. 10.1002/bit.27101
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- Article
Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture.
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- Biotechnology & Bioengineering, 2019, v. 116, n. 3, p. 677, doi. 10.1002/bit.26891
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- Article
A reference genome of the Chinese hamster based on a hybrid assembly strategy.
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- Biotechnology & Bioengineering, 2018, v. 115, n. 8, p. 2087, doi. 10.1002/bit.26722
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- Article
Karyotype variation of CHO host cell lines over time in culture characterized by chromosome counting and chromosome painting.
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- Biotechnology & Bioengineering, 2018, v. 115, n. 1, p. 165, doi. 10.1002/bit.26453
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- Article
Preselection of recombinant gene integration sites enabling high transcription rates in CHO cells using alternate start codons and recombinase mediated cassette exchange.
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- Biotechnology & Bioengineering, 2017, v. 114, n. 11, p. 2616, doi. 10.1002/bit.26388
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- Article
Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.
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- Biotechnology & Bioengineering, 2016, v. 113, n. 10, p. 2241, doi. 10.1002/bit.25990
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- Article
Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data.
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- Biotechnology & Bioengineering, 2015, v. 112, n. 7, p. 1488, doi. 10.1002/bit.25539
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- Article
Chinese hamster genome database: An online resource for the CHO community at.
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- Biotechnology & Bioengineering, 2012, v. 109, n. 6, p. 1353, doi. 10.1002/bit.24374
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- Article
A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells.
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- Biotechnology & Bioengineering, 2012, v. 109, n. 6, p. 1376, doi. 10.1002/bit.24490
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- Publication type:
- Article
Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics.
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- Biotechnology & Bioengineering, 2012, v. 109, n. 6, p. 1386, doi. 10.1002/bit.24476
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- Publication type:
- Article
Selection of CHO host cell subclones with increased specific antibody production rates by repeated cycles of transient transfection and cell sorting.
- Published in:
- Biotechnology & Bioengineering, 2011, v. 108, n. 2, p. 386, doi. 10.1002/bit.22946
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- Article
Publisher Correction: Engineered bidirectional promoters enable rapid multi-gene co-expression optimization.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07112-1
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- Article
ChromaWizard: An open source image analysis software for multicolor fluorescence in situ hybridization analysis.
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- Cytometry. Part A, 2018, v. 93, n. 7, p. 749, doi. 10.1002/cyto.a.23505
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- Article
CHOmine: an integrated data warehouse for CHO systems biology and modeling.
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- Database: The Journal of Biological Databases & Curation, 2017, v. 2017, n. 1, p. 1, doi. 10.1093/database/bax034
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- Article
Recon 2.2: from reconstruction to model of human metabolism.
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- Metabolomics, 2016, v. 12, n. 7, p. 1, doi. 10.1007/s11306-016-1051-4
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- Article
Baculovirus surface display: construction and screening of a eukaryotic epitope library.
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- Nucleic Acids Research, 1998, v. 26, n. 7, p. 1718, doi. 10.1093/nar/26.7.1718
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- Article
Optimization of Sorting Conditions for the Selection of Stable, High-Producing Mammalian Cell Lines.
- Published in:
- Biotechnology Progress, 1999, v. 15, n. 5, p. 953, doi. 10.1021/bp990089g
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- Article
Key Challenges in Designing CHO Chassis Platforms.
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- Processes, 2020, v. 8, n. 6, p. 643, doi. 10.3390/pr8060643
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- Article
Inclusion of maintenance energy improves the intracellular flux predictions of CHO.
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- PLoS Computational Biology, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.pcbi.1009022
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- Article
Diamine oxidase knockout mice are not hypersensitive to orally or subcutaneously administered histamine.
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- Inflammation Research, 2022, v. 71, n. 4, p. 497, doi. 10.1007/s00011-022-01558-2
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- Article
Simple, sensitive and specific quantification of diamine oxidase activity in complex matrices using newly discovered fluorophores derived from natural substrates.
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- Inflammation Research, 2020, v. 69, n. 9, p. 937, doi. 10.1007/s00011-020-01359-5
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- Publication type:
- Article
Systematic use of synthetic 5′-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories.
- Published in:
- Nucleic Acids Research, 2020, v. 48, n. 20, p. e119, doi. 10.1093/nar/gkaa847
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- Publication type:
- Article
Engineered bidirectional promoters enable rapid multi-gene co-expression optimization.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05915-w
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- Publication type:
- Article
Next-generation sequencing of the CHO cell transcriptome.
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- 2011
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- Abstract
Glycosylation site Asn168 is important for slow in vivo clearance of recombinant human diamine oxidase heparin-binding motif mutants.
- Published in:
- Glycobiology, 2022, v. 32, n. 5, p. 404, doi. 10.1093/glycob/cwab122
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- Publication type:
- Article
Human diamine oxidase cellular binding and internalization in vitro and rapid clearance in vivo are not mediated by N-glycans but by heparan sulfate proteoglycan interactions.
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- Glycobiology, 2021, v. 31, n. 4, p. 444, doi. 10.1093/glycob/cwaa090
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- Publication type:
- Article
Combined approach of selective and accelerated cloning for microfluidic chip‐based system increases clone specific productivity.
- Published in:
- Biotechnology Journal, 2024, v. 19, n. 5, p. 1, doi. 10.1002/biot.202300488
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- Article
Subcloning induces changes in the DNA‐methylation pattern of outgrowing Chinese hamster ovary cell colonies.
- Published in:
- Biotechnology Journal, 2021, v. 16, n. 6, p. 1, doi. 10.1002/biot.202000350
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- Article
Error propagation in constraint‐based modeling of Chinese hamster ovary cells.
- Published in:
- Biotechnology Journal, 2021, v. 16, n. 4, p. 1, doi. 10.1002/biot.202000320
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- Publication type:
- Article
Bioinformatic Identification of Chinese Hamster Ovary (CHO) Cold‐Shock Genes and Biological Evidence of their Cold‐Inducible Promoters.
- Published in:
- Biotechnology Journal, 2020, v. 15, n. 3, p. 1, doi. 10.1002/biot.201900359
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- Article
mRNA Transfection into CHO‐Cells Reveals Production Bottlenecks.
- Published in:
- Biotechnology Journal, 2020, v. 15, n. 2, p. N.PAG, doi. 10.1002/biot.201900198
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- Article
Novel Promoters Derived from Chinese Hamster Ovary Cells via In Silico and In Vitro Analysis.
- Published in:
- Biotechnology Journal, 2019, v. 14, n. 11, p. N.PAG, doi. 10.1002/biot.201900125
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- Publication type:
- Article
Genetic and Epigenetic Variation across Genes Involved in Energy Metabolism and Mitochondria of Chinese Hamster Ovary Cell Lines.
- Published in:
- Biotechnology Journal, 2019, v. 14, n. 7, p. N.PAG, doi. 10.1002/biot.201800681
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- Publication type:
- Article
CRISPR/Cas9‐Mediated Knockout of MicroRNA‐744 Improves Antibody Titer of CHO Production Cell Lines.
- Published in:
- Biotechnology Journal, 2019, v. 14, n. 5, p. N.PAG, doi. 10.1002/biot.201800477
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- Publication type:
- Article
Enhancing CHO by Systems Biotechnology.
- Published in:
- Biotechnology Journal, 2018, v. 13, n. 10, p. 1, doi. 10.1002/biot.201800488
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- Publication type:
- Article