Works matching AU Borghgraef, Peter

Results: 37

Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase.

Published in:

Molecular Brain, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-6606-6-27

By:

Maurin, Hervé;
Lechat, Benoit;
Dewachter, Ilse;
Ris, Laurence;
Louis, Justin V.;
Borghgraef, Peter;
Devijver, Herman;
Jaworski, Tomasz;
Van Leuven, Fred

Publication type:

Article

Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29713-7

By:

Fraire, Juan C.;
Shaabani, Elnaz;
Sharifiaghdam, Maryam;
Rombaut, Matthias;
Hinnekens, Charlotte;
Hua, Dawei;
Ramon, Jana;
Raes, Laurens;
Bolea-Fernandez, Eduardo;
Brans, Toon;
Vanhaecke, Frank;
Borghgraef, Peter;
Huang, Chaobo;
Sauvage, Félix;
Vanhaecke, Tamara;
De Kock, Joery;
Xiong, Ranhua;
De Smedt, Stefaan;
Braeckmans, Kevin

Publication type:

Article

Publisher Correction: Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells.

Published in:

2022

By:

Fraire, Juan C.;
Shaabani, Elnaz;
Sharifiaghdam, Maryam;
Rombaut, Matthias;
Hinnekens, Charlotte;
Hua, Dawei;
Ramon, Jana;
Raes, Laurens;
Bolea-Fernandez, Eduardo;
Brans, Toon;
Vanhaecke, Frank;
Borghgraef, Peter;
Huang, Chaobo;
Sauvage, Félix;
Vanhaecke, Tamara;
De Kock, Joery;
Xiong, Ranhua;
De Smedt, Stefaan;
Braeckmans, Kevin

Publication type:

Correction Notice

Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29713-7

By:

Fraire, Juan C.;
Shaabani, Elnaz;
Sharifiaghdam, Maryam;
Rombaut, Matthias;
Hinnekens, Charlotte;
Hua, Dawei;
Ramon, Jana;
Raes, Laurens;
Bolea-Fernandez, Eduardo;
Brans, Toon;
Vanhaecke, Frank;
Borghgraef, Peter;
Huang, Chaobo;
Sauvage, Félix;
Vanhaecke, Tamara;
De Kock, Joery;
Xiong, Ranhua;
De Smedt, Stefaan;
Braeckmans, Kevin

Publication type:

Article

Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29713-7

By:

Fraire, Juan C.;
Shaabani, Elnaz;
Sharifiaghdam, Maryam;
Rombaut, Matthias;
Hinnekens, Charlotte;
Hua, Dawei;
Ramon, Jana;
Raes, Laurens;
Bolea-Fernandez, Eduardo;
Brans, Toon;
Vanhaecke, Frank;
Borghgraef, Peter;
Huang, Chaobo;
Sauvage, Félix;
Vanhaecke, Tamara;
De Kock, Joery;
Xiong, Ranhua;
De Smedt, Stefaan;
Braeckmans, Kevin

Publication type:

Article

Early Structural and Functional Defects in Synapses and Myelinated Axons in Stratum Lacunosum Moleculare in Two Preclinical Models for Tauopathy.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0087605

By:

Maurin, Hervé;
Chong, Seon-Ah;
Kraev, Igor;
Davies, Heather;
Kremer, Anna;
Seymour, Claire Marie;
Lechat, Benoit;
Jaworski, Tomasz;
Borghgraef, Peter;
Devijver, Herman;
Callewaert, Geert;
Stewart, Michael G.;
Van Leuven, Fred

Publication type:

Article

Increasing Brain Protein O-GlcNAc-ylation Mitigates Breathing Defects and Mortality of Tau.P301L Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084442

By:

Borghgraef, Peter;
Menuet, Clément;
Theunis, Clara;
Louis, Justin V.;
Devijver, Herman;
Maurin, Hervé;
Smet-Nocca, Caroline;
Lippens, Guy;
Hilaire, Gerard;
Gijsen, Harrie;
Moechars, Dieder;
Van Leuven, Fred

Publication type:

Article

Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072301

By:

Theunis, Clara;
Crespo-Biel, Natalia;
Gafner, Valérie;
Pihlgren, Maria;
López-Deber, María Pilar;
Reis, Pedro;
Hickman, David T.;
Adolfsson, Oskar;
Chuard, Nathalie;
Ndao, Dorin Mlaki;
Borghgraef, Peter;
Devijver, Herman;
Van Leuven, Fred;
Pfeifer, Andrea;
Muhs, Andreas

Publication type:

Article

Tauopathy Differentially Affects Cell Adhesion Molecules in Mouse Brain: Early Down-Regulation of Nectin-3 in Stratum Lacunosum Moleculare

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063589

By:

Maurin, Hervé;
Seymour, Claire Marie;
Lechat, Benoit;
Borghgraef, Peter;
Devijver, Herman;
Jaworski, Tomasz;
Schmidt, Mathias V.;
Kuegler, Sebastian;
Van Leuven, Fred

Publication type:

Article

Age-Related Impairment of Ultrasonic Vocalization in Tau.P301L Mice: Possible Implication for Progressive Language Disorders.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0025770

By:

Menuet, Clément;
Cazals, Yves;
Gestreau, Christian;
Borghgraef, Peter;
Gielis, Lies;
Dutschmann, Mathias;
Van Leuven, Fred;
Hilaire, Gérard

Publication type:

Article

AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice.

Published in:

PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007280

By:

Jaworski, Tomasz;
Dewachter, Ilse;
Lechat, Benoit;
Croes, Sophie;
Termont, Annelies;
Demedts, David;
Borghgraef, Peter;
Devijver, Herman;
Filipkowski, Robert K.;
Kaczmarek, Leszek;
Kügler, Sebastian;
Van Leuven, Fred

Publication type:

Article

Cutaneous distribution of orally administered itraconazole in guinea pigs, studied by autoradiography.

Published in:

Journal of the European Academy of Dermatology & Venereology, 1994, v. 3, n. 4, p. 475, doi. 10.1111/j.1468-3083.1994.tb00403.x

By:

Stoppie, Paul;
Borghgraef, Peter;
Borgers, Marcel

Publication type:

Article

Morphological alterations of the choroid plexus epithelium in Alzheimer's disease: Molecular and cell biology/APP/abeta/amyloid.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045752

By:

Van Cauwenberghe, Caroline;
Vandendriessche, Charysse;
Kremer, Anneke;
De Rycke, Riet;
Borghgraef, Peter;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Lippens, Saskia;
Vandenbroucke, Roosmarijn E

Publication type:

Article

Epileptogenicity and precocious mortality of bigenic biat mice that express amyloid and tau.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P356, doi. 10.1016/j.jalz.2015.06.243

By:

Van Leuven, Fred;
Maurin, Hervé;
Kremer, Anna;
Chong, Seon-Ah;
Crespo-Biel, Natalia;
Borghgraef, Peter;
Lechat, Benoit;
Theunis, Clara;
Devijver, Herman;
Callewaert, Geert

Publication type:

Article

Phospho-tau–specific vaccine for the treatment of tau pathology

Published in:

2012

By:

Adolfsson, Oskar;
Gafner, Valerie;
Theunis, Clara;
Pihlgren, Maria;
Crespo-Biel, Natalia;
Papin, Stephanie;
Lopez Deber, Maria Pilar;
Borghgraef, Peter;
Piorkowska, Kasia;
Devijver, Herman;
Hickman, David T.;
Chuard, Nathalie;
Reis, Pedro;
Antoniello, Katia;
Buccarello, Anna Lucia;
Paganetti, Paolo;
Pfeifer, Andrea;
Van Leuven, Fred;
Muhs, Andreas

Publication type:

Abstract

Timeline of biochemical and pathological markers in mono- and Bigenic models for tauopathy

Published in:

2012

By:

Crespo Biel, Natalia;
Theunis, Clara;
Borghgraef, Peter;
Demedts, David;
Devijver, Herman;
Van Leuven, Fred

Publication type:

Abstract

Novel phospho-Tau specific monoclonal antibodies for the treatment of Tau-mediated pathology

Published in:

2011

By:

Adolfsson, Oskar;
Crespo-Biel, Natalia;
Pihlgren, Maria;
Theunis, Clara;
Gafner, Valerie;
Borghgraef, Peter;
Lopez Deber, Maria Pilar;
Devijver, Herman;
Hickman, David T.;
Buccarello, Anna Lucia;
Chuard, Nathalie

Publication type:

Abstract

Novel phospho-tau-specific liposome-based vaccines to treat tau pathology

Published in:

2011

By:

Theunis, Clara;
Crespo-Biel, Natalia;
Pihlgren, Maria;
Borghgraef, Peter;
Devijver, Herman;
Gafner, Valerie;
Hickman, David;
Chuard, Nathalie;
Lopez Deber, Maria Pilar;
Reis, Pedro;
Buccarello, Anna Lucia;
Adolfsson, Oskar;
Roeber, Sigrun;
Kretzschmar, Hans;
Pfeifer, Andrea;
Muhs, Andreas;
Van Leuven, Fred

Publication type:

Abstract

Life-span of Tau.P301L mice: Modulation by GSK3b and O-GlcNAcylation

Published in:

2011

By:

Van Leuven, Fred;
Borghgraef, Peter;
Menuet, Clement;
Devijver, Herman;
Gielis, Lies;
Lechat, Benoit;
Gijsen, Harry;
Moechars, Dieder;
Hilaire, Gerard

Publication type:

Abstract

Time-line of pathology and defects in biAT mice with combined amyloid-tau pathology

Published in:

2011

By:

Kremer, Anna;
Maurin, Herve;
Lechat, Benoit;
Borghgraef, Peter;
Devijver, Herman;
Van Leuven, Fred

Publication type:

Abstract

Life-span of Tau.P301L mice: Modulation by GSK3b and O-GlcNAc-ylation

Published in:

2011

By:

Borghgraef, Peter;
Menuet, Clément;
Devijver, Herman;
Gielis, Lies;
Lechat, Benoit;
Gijsen, Harry;
Moechars, Dieder;
Hilaire, Gérard;
Van Leuven, Fred

Publication type:

Abstract

P3-277: Severe neurodegeneration is intimately related to inflammation in cdk5/p25 inducible mice

Published in:

2006

By:

Muyllaert, David;
Terwel, Dick;
Borghgraef, Peter;
Van Leuven, Fred

Publication type:

Abstract

O4-05-04: Co-expression of GSK-3β with tau-P301L in double transgenic mice dramatically increases forebrain tauopathy but decreases hindbrain pathology and rescues mortality

Published in:

2006

By:

Terwel, Dick;
Muyllaert, David;
Borghgraef, Peter;
Van Leuven, Fred

Publication type:

Abstract

O3-03-08: Differential effects of presenilin-1 deficiency and mutant presenilin-1 on synaptic plasticity

Published in:

2006

By:

Dewachter, Ilse;
Ris, Laurence;
Croes, Sophie;
Borghgraef, Peter;
Voets, Thomas;
Nilius, Bernd;
Godaux, Emile;
Van Leuven, Fred

Publication type:

Abstract

O2-04-01: Combined amyloid and tau-pathology in APPV717I X taup301L double transgenic mice: Increased survival correlates with less hindbrain pathology, despite dramatic forebrain tauopathy

Published in:

2006

By:

Muyllaert, David;
Terwel, Dick;
Dewachter, Ilse;
Borghgraef, Peter;
Van Leuven, Fred

Publication type:

Abstract

P3-277: Severe neurodegeneration is intimately related to inflammation in cdk5/p25 inducible mice

Published in:

2006

By:

Muyllaert, David;
Terwel, Dick;
Borghgraef, Peter;
Van Leuven, Fred

Publication type:

Abstract

O4-05-04: Co-expression of GSK-3β with tau-P301L in double transgenic mice dramatically increases forebrain tauopathy but decreases hindbrain pathology and rescues mortality

Published in:

2006

By:

Terwel, Dick;
Muyllaert, David;
Borghgraef, Peter;
Van Leuven, Fred

Publication type:

Abstract

O3-03-08: Differential effects of presenilin-1 deficiency and mutant presenilin-1 on synaptic plasticity

Published in:

2006

By:

Dewachter, Ilse;
Ris, Laurence;
Croes, Sophie;
Borghgraef, Peter;
Voets, Thomas;
Nilius, Bernd;
Godaux, Emile;
Van Leuven, Fred

Publication type:

Abstract

O2-04-01: Combined amyloid and tau-pathology in APPV717I X taup301L double transgenic mice: Increased survival correlates with less hindbrain pathology, despite dramatic forebrain tauopathy

Published in:

2006

By:

Muyllaert, David;
Terwel, Dick;
Dewachter, Ilse;
Borghgraef, Peter;
Van Leuven, Fred

Publication type:

Abstract

Virosome-based active immunization targets soluble amyloid species rather than plaques in a transgenic mouse model of Alzheimer’s disease.

Published in:

Journal of Molecular Neuroscience, 2005, v. 27, n. 2, p. 157, doi. 10.1385/JMN:27:2:157

By:

Zurbriggen, Rinaldo;
Amacker, Mario;
Kammer, Andreas;
Westerfeld, Nicole;
Borghgraef, Peter;
Leuven, Fred;
Auwera, Ingrid;
Wera, Stefaan

Publication type:

Article

Involvement of the Choroid Plexus in the Pathogenesis of Niemann-Pick Disease Type C.

Published in:

Frontiers in Cellular Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fncel.2021.757482

By:

Van Hoecke, Lien;
Van Cauwenberghe, Caroline;
Dominko, Kristina;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Castelein, Jonas;
Xie, Junhua;
Claeys, Wouter;
Vandendriessche, Charysse;
Kremer, Anna;
Borghgraef, Peter;
De Rycke, Riet;
Hecimovic, Silva;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Longitudinal assessment of cerebral perfusion and vascular response to hypoventilation in a bigenic mouse model of Alzheimer's disease with amyloid and tau pathology.

Published in:

NMR in Biomedicine, 2019, v. 32, n. 1, p. 1, doi. 10.1002/nbm.4037

By:

Govaerts, Kristof;
Lechat, Benoit;
Struys, Tom;
Kremer, Anna;
Borghgraef, Peter;
Van Leuven, Fred;
Himmelreich, Uwe;
Dresselaers, Tom

Publication type:

Article

Terminal hypothermic Tau. P301 L mice have increased Tau phosphorylation independently of glycogen synthase kinase 3α/β.

Published in:

European Journal of Neuroscience, 2014, v. 40, n. 2, p. 2442, doi. 10.1111/ejn.12595

By:

Maurin, Hervé;
Lechat, Benoit;
Borghgraef, Peter;
Devijver, Herman;
Jaworski, Tomasz;
Leuven, Fred

Publication type:

Article

GSK-3?/? kinases and amyloid production in vivo.

Published in:

Nature, 2011, v. 480, n. 7376, p. E4, doi. 10.1038/nature10615

By:

Jaworski, Tomasz;
Dewachter, Ilse;
Lechat, Benoit;
Gees, Maarten;
Kremer, Anna;
Demedts, David;
Borghgraef, Peter;
Devijver, Herman;
Kügler, Seb;
Patel, Satish;
Woodgett, Jim R.;
Van Leuven, Fred

Publication type:

Article

Early Improved and Late Defective Cognition Is Reflected by Dendritic Spines in Tau.P301L Mice.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 49, p. 18036, doi. 10.1523/JNEUROSCI.4859-11.2011

By:

Kremer, Anna;
Maurin, Hervé;
Demedts, David;
Devijver, Herman;
Borghgraef, Peter;
Van Leuven, Fred

Publication type:

Article

Upper Airway Dysfunction of Tau-P301L Mice Correlates with Tauopathy in Midbrain and Ponto-Medullary Brainstem Nuclei.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 5, p. 1810, doi. 10.1523/JNEUROSCI.5261-09.2010

By:

Mathias Dutschmann;
Menuet, Clement;
Stettner, Georg M.;
Gestreau, Christian;
Borghgraef, Peter;
Devijver, Herman;
Gielis, Lies;
Hilaire, Gerard;
van Leuven, Fred

Publication type:

Article

Improved Long-Term Potentiation and Memory in Young Tau-P301L Transgenic Mice before Onset of Hyperphosphorylation and Tauopathy.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 13, p. 3514, doi. 10.1523/JNEUROSCI.5425-05.2006

By:

Boekhoorn, Karin;
Terwel, Dick;
Biemans, Barbara;
Borghgraef, Peter;
Wiegert, Olof;
Ramakers, Ger J. A.;
De Vos, Koos;
Krugers, Harm;
Tomiyama, Takami;
Mori, Hiroshi;
Joels, Marian;
Van Leuven, Fred;
Lucassen, Paul J.

Publication type:

Article