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Supercharging Prions via Amyloid‐Selective Lysine Acetylation.
- Published in:
- Angewandte Chemie, 2021, v. 133, n. 27, p. 15196, doi. 10.1002/ange.202103548
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- Publication type:
- Article
Il-10 signaling reduces survival in mouse models of synucleinopathy.
- Published in:
- NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00169-8
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- Publication type:
- Article
Impact of APOE genotype on prion-type propagation of tauopathy.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01359-y
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- Publication type:
- Article
Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01191-w
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- Publication type:
- Article
Passive (Amyloid-β Immunotherapy Attenuates Monoaminergic Axonal Degeneration in the AβPPswe/PS1dE9 Mice.
- Published in:
- Journal of Alzheimer's Disease, 2011, v. 23, n. 2, p. 271, doi. 10.3233/JAD-2010-101602
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- Publication type:
- Article
Passive (amyloid-β) immunotherapy attenuates monoaminergic axonal degeneration in the AβPPswe/PS1dE9 mice.
- Published in:
- 2011
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- Publication type:
- journal article
Exploring the pathologic synergy between amyloid β and tau: Molecular and cell biology/tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043477
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- Publication type:
- Article
Using seeding models to understand strain differences from Alzheimer's disease and pathological aging brains: Development of new models and analysis methods/seeding and spreading of proteinopathies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043302
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- Publication type:
- Article
Exacerbation of tau pathology by pre‐existing amyloidosis in novel transgenic mice: Dysregulation of protein synthesis in neurodegeneration.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042291
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- Publication type:
- Article
Thinking laterally about neurodegenerative proteinopathies.
- Published in:
- 2013
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- Publication type:
- journal article
Thinking laterally about neurodegenerative proteinopathies.
- Published in:
- Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 1847, doi. 10.1172/JCI66029
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- Publication type:
- Article
Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
- Published in:
- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03373-1
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- Publication type:
- Article
Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS.
- Published in:
- Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00110
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- Publication type:
- Article
Metal-Deficient Aggregates and Diminished Copper Found in Cells Expressing SOD1 Mutations that Cause ALS.
- Published in:
- Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00110
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- Publication type:
- Article
Quantitative comparison of dense-core amyloid plaque burdens in Alzheimer’s disease patients and amyloid precursor protein transgenic mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P353, doi. 10.1016/j.jalz.2015.06.236
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- Publication type:
- Article
Co-expression of app and tau accelerates cognitive decline in a new triple transgenic model that allows for accounting for the effect of age as a risk factor for Alzheimer’s disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P852, doi. 10.1016/j.jalz.2015.08.018
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- Publication type:
- Article
A transgenic mouse model of amyloid β oligomers: Pathological effects of the E693Δ mutation in amyloid precursor protein in vivo
- Published in:
- 2009
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- Publication type:
- Abstract
Environmental enrichment mitigates cognitive deficits in APP/PS1 transgenic mice
- Published in:
- 2005
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- Publication type:
- Abstract
β-Amyloid Peptide Vaccination Results in Marked Changes in Serum and Brain Aβ Levels in APPswe/PS1ΔE9 Mice, as Detected by SELDI-TOF-Based ProteinChip[sup ®] Technology.
- Published in:
- DNA & Cell Biology, 2001, v. 20, n. 11, p. 713, doi. 10.1089/10445490152717578
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- Publication type:
- Article
Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype.
- Published in:
- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0393-5
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- Publication type:
- Article
Murine Aß over-production produces diffuse and compact Alzheimer-type amyloid deposits.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, p. 1, doi. 10.1186/s40478-015-0252-9
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- Publication type:
- Article
Subcellular Localization of Matrin 3 Containing Mutations Associated with ALS and Distal Myopathy.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142144
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- Publication type:
- Article
Analysis of Mutant SOD1 Electrophoretic Mobility by Blue Native Gel Electrophoresis; Evidence for Soluble Multimeric Assemblies.
- Published in:
- PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104583
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- Publication type:
- Article
An Analysis of Interactions between Fluorescently-Tagged Mutant and Wild-Type SOD1 in Intracellular Inclusions.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083981
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- Publication type:
- Article
Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067680
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- Publication type:
- Article
Analysis of Proteolytic Processes and Enzymatic Activities in the Generation of Huntingtin N-Terminal Fragments in an HEK293 Cell Model.
- Published in:
- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050750
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- Publication type:
- Article
Identification of Proteins Sensitive to Thermal Stress in Human Neuroblastoma and Glioma Cell Lines.
- Published in:
- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049021
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- Publication type:
- Article
Role of Disulfide Cross-Linking of Mutant SOD1 in the Formation of Inclusion-Body-Like Structures.
- Published in:
- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047838
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- Publication type:
- Article
Downregulation of Genes Involved in Metabolism and Oxidative Stress in the Peripheral Leukocytes of Huntington's Disease Patients.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046492
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- Publication type:
- Article
Sex-Dependent Alterations in Social Behaviour and Cortical Synaptic Activity Coincide at Different Ages in a Model of Alzheimer's Disease.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046111
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- Publication type:
- Article
A Technique for Performing Electrical Impedance Myography in the Mouse Hind Limb: Data in Normal and ALS SOD1 G93A Animals.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045004
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- Publication type:
- Article
Fragments of HdhQ150 Mutant Huntingtin Form a Soluble Oligomer Pool That Declines with Aggregate Deposition upon Aging.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044457
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- Publication type:
- Article
Monitoring CSF Proteome Alterations in Amyotrophic Lateral Sclerosis: Obstacles and Perspectives in Translating a Novel Marker Panel to the Clinic.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044401
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- Publication type:
- Article
A Preclinical Assessment of Neural Stem Cells as Delivery Vehicles for Anti-Amyloid Therapeutics.
- Published in:
- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034097
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- Publication type:
- Article
Analysis of Chaperone mRNA Expression in the Adult Mouse Brain by Meta Analysis of the Allen Brain Atlas.
- Published in:
- PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013675
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- Publication type:
- Article
Receptor-Associated Protein (RAP) Plays a Central Role in Modulating Aβ Deposition in APP/PS1 Transgenic Mice.
- Published in:
- PLoS ONE, 2008, v. 3, n. 9, p. 1, doi. 10.1371/journal.pone.0003159
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- Publication type:
- Article
Messenger RNA Oxidation Occurs Early in Disease Pathogenesis and Promotes Motor Neuron Degeneration in ALS.
- Published in:
- PLoS ONE, 2008, v. 3, n. 8, p. 1, doi. 10.1371/journal.pone.0002849
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- Publication type:
- Article
The Value of Transgenic Models for the Study of Neurodegenerative Diseases.
- Published in:
- Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 179, doi. 10.1111/j.1749-6632.2000.tb06920.x
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- Publication type:
- Article
Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis.
- Published in:
- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00911-y
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- Publication type:
- Article
Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0733-3
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- Publication type:
- Article
Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3.
- Published in:
- Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0631-0
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- Publication type:
- Article
Retraction Note: Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype.
- Published in:
- 2017
- By:
- Publication type:
- Correction Notice
Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer's Disease.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/biom12070886
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- Publication type:
- Article
Amyloid Pathology Is Associated with Progressive Monoaminergic Neurodegeneration in a Transgenic Mouse Model of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 51, p. 13805, doi. 10.1523/JNEUROSCI.4218-08.2008
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- Publication type:
- Article
Alzheimer's-Type Amyloidosis in Transgenic Mice Impairs Survival of Newborn Neurons Derived from Adult Hippocampal Neurogenesis.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 25, p. 6771, doi. 10.1523/JNEUROSCI.5564-06.2007
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- Publication type:
- Article
BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic Functions.
- Published in:
- Journal of Neuroscience, 2005, v. 25, n. 50, p. 11693, doi. 10.1523/JNEUROSCI.2766-05.2005
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- Publication type:
- Article
Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2005, v. 25, n. 21, p. 5217, doi. 10.1523/JNEUROSCI.5080-04.2005
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- Publication type:
- Article
Widespread and Efficient Transduction of Spinal Cord and Brain Following Neonatal AAV Injection and Potential Disease Modifying Effect in ALS Mice.
- Published in:
- Molecular Therapy, 2015, v. 23, n. 1, p. 53, doi. 10.1038/mt.2014.180
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- Publication type:
- Article
Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau.
- Published in:
- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01664-0
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- Publication type:
- Article
Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy.
- Published in:
- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01581-2
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- Publication type:
- Article