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TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer.
- Published in:
- 2010
- By:
- Publication type:
- journal article
The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 4, p. 1718, doi. 10.1093/nar/gkv1492
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- Publication type:
- Article
Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 8, p. 4996, doi. 10.1093/nar/gku160
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- Publication type:
- Article
Hemoglobin-Based Oxygen Carrier Mitigates Transfusion-Mediated Pancreas Cancer Progression.
- Published in:
- Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2013, v. 20, n. 6, p. 2073, doi. 10.1245/s10434-012-2842-0
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- Publication type:
- Article
Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.
- Published in:
- Scientific Reports, 2015, p. 17066, doi. 10.1038/srep17066
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- Publication type:
- Article
ATM Regulates Insulin-Like Growth Factor 1-Secretory Clusterin (IGF-1-sCLU) Expression that Protects Cells against Senescence.
- Published in:
- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099983
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- Publication type:
- Article
New tricks for old drugs: the anticarcinogenic potential of DNA repair inhibitors.
- Published in:
- Journal of Molecular Histology, 2006, v. 37, n. 5-7, p. 203, doi. 10.1007/s10735-006-9043-8
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- Publication type:
- Article
Cellular and Molecular Responses to Topoisomerase I Poisons: Exploiting Synergy for Improved Radiotherapy.
- Published in:
- Annals of the New York Academy of Sciences, 2000, v. 922, n. 1, p. 274, doi. 10.1111/j.1749-6632.2000.tb07045.x
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- Publication type:
- Article
Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by β-lapachone.
- Published in:
- Cancer & Metabolism, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40170-015-0137-1
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- Publication type:
- Article
A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage.
- Published in:
- Oncogene, 2003, v. 22, n. 47, p. 7376, doi. 10.1038/sj.onc.1206941
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- Publication type:
- Article
Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation.
- Published in:
- Oncogene, 2003, v. 22, n. 37, p. 5813, doi. 10.1038/sj.onc.1206680
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- Publication type:
- Article
NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-11238-1
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- Publication type:
- Article
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
- Published in:
- Nature Cell Biology, 2003, v. 5, n. 4, p. 320, doi. 10.1038/ncb950
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- Publication type:
- Article
Isolation of Ku70‐binding proteins (KUBs).
- Published in:
- Nucleic Acids Research, 1999, v. 27, n. 10, p. 2165, doi. 10.1093/nar/27.10.2165
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- Publication type:
- Article
Expanding antitumor therapeutic windows by targeting cancer-specific nicotinamide adenine dinucleotide phosphate-biogenesis pathways.
- Published in:
- Clinical Pharmacology, 2015, v. 7, p. 57, doi. 10.2147/CPAA.S79760
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- Publication type:
- Article
Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin.
- Published in:
- FEBS Journal, 2009, v. 276, n. 14, p. 4208, doi. 10.1111/j.1742-4658.2009.07093.x
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- Publication type:
- Article
Combined radiation and p53 gene therapy of malignant glioma cells.
- Published in:
- Cancer Gene Therapy, 1999, v. 6, n. 2, p. 155, doi. 10.1038/sj.cgt.7700009
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- Publication type:
- Article
Role of DNA mismatch repair in apoptotic responses to therapeutic agents.
- Published in:
- Environmental & Molecular Mutagenesis, 2004, v. 44, n. 4, p. 249
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- Publication type:
- Article
Prodrug Strategy to Achieve Lyophilizable, High Drug Loading Micelle Formulations Through Diester Derivatives of β-Lapachone.
- Published in:
- Advanced Healthcare Materials, 2014, v. 3, n. 8, p. 1210, doi. 10.1002/adhm.201300590
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- Publication type:
- Article
Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.
- Published in:
- Carcinogenesis, 2010, v. 31, n. 10, p. 1889, doi. 10.1093/carcin/bgq153
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- Publication type:
- Article
Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks.
- Published in:
- Nature Communications, 2014, v. 5, n. 12, p. 5811, doi. 10.1038/ncomms6811
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- Publication type:
- Article
Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis.
- Published in:
- 2018
- By:
- Publication type:
- journal article
cRGD-Functionalized Polymer Micelles for Targeted Doxorubicin DeliveryThis research is supported by the National Institutes of Health (R01-CA-90 696). N.N. acknowledges the Royal Thai Government for a predoctoral fellowship support. X.T.S. acknowledges fellowship support from the Ohio Biomedical Research and Technology Trust fund. We thank Dr. Steven Eppell and Zhilei Liu for their help with atomic force microscopy.
- Published in:
- Angewandte Chemie, 2004, v. 116, n. 46, p. 6483, doi. 10.1002/ange.200460800
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- Publication type:
- Article
Mornings with art, lessons learned: Feedback regulation, restriction threshold biology, and redundancy govern molecular stress responses.
- Published in:
- Journal of Cellular Physiology, 2006, v. 209, n. 3, p. 604, doi. 10.1002/jcp.20783
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- Publication type:
- Article
Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature.
- Published in:
- Genes, Chromosomes & Cancer, 2011, v. 50, n. 4, p. 275, doi. 10.1002/gcc.20853
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- Publication type:
- Article
DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets.
- Published in:
- 2009
- By:
- Publication type:
- journal article
cRGD-Functionalized Polymer Micelles for Targeted Doxorubicin DeliveryThis research is supported by the National Institutes of Health (R01-CA-90 696). N.N. acknowledges the Royal Thai Government for a predoctoral fellowship support. X.T.S. acknowledges fellowship support from the Ohio Biomedical Research and Technology Trust fund. We thank Dr. Steven Eppell and Zhilei Liu for their help with atomic force microscopy.
- Published in:
- Angewandte Chemie International Edition, 2004, v. 43, n. 46, p. 6323, doi. 10.1002/anie.200460800
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- Publication type:
- Article
The Transcription Factor TFII-I Promotes DNA Translesion Synthesis and Genomic Stability.
- Published in:
- PLoS Genetics, 2014, v. 10, n. 6, p. 1, doi. 10.1371/journal.pgen.1004419
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- Publication type:
- Article
Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer.
- Published in:
- Journal of Surgical Oncology, 2017, v. 116, n. 1, p. 83, doi. 10.1002/jso.24624
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- Publication type:
- Article
The Effect of Salbutamol on Mood in Normal Subjects.
- Published in:
- Human Psychopharmacology: Clinical & Experimental, 1994, v. 9, n. 6, p. 435, doi. 10.1002/hup.470090606
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- Publication type:
- Article
Antagonistic Effects of Anti-EMMPRIN Antibody When Combined with Chemotherapy Against Hypovascular Pancreatic Cancers.
- Published in:
- Molecular Imaging & Biology, 2014, v. 16, n. 1, p. 85, doi. 10.1007/s11307-013-0665-4
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- Publication type:
- Article
MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer.
- Published in:
- Frontiers in Oncology, 2020, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.536377
- By:
- Publication type:
- Article
Targeting Base Excision Repair in Cancer: NQO1-Bioactivatable Drugs Improve Tumor Selectivity and Reduce Treatment Toxicity Through Radiosensitization of Human Cancer.
- Published in:
- Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.01575
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- Publication type:
- Article
Synergistic Effect of β-Lapachone and Aminooxyacetic Acid on Central Metabolism in Breast Cancer.
- Published in:
- Nutrients, 2022, v. 14, n. 15, p. 3020, doi. 10.3390/nu14153020
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- Publication type:
- Article
XRN2 Links Transcription Termination to DNA Damage and Replication Stress.
- Published in:
- PLoS Genetics, 2016, v. 12, n. 7, p. 1, doi. 10.1371/journal.pgen.1006107
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- Publication type:
- Article