Works by Bonner, Caroline

Results: 27

The role of the glucagon‐FGF21 axis in improving beta cell function during glucose intolerance and SGLT2 inhibition.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 2, p. 885, doi. 10.1111/dom.16089

By:

Moreno‐Lopez, Maria;
Louvet, Isaline;
Delalleau, Nathalie;
Acosta‐Montalvo, Ana;
Thevenet, Julien;
Pasquetti, Gianni;
Gmyr, Valery;
Kerr‐Conte, Julie;
Pattou, Francois;
Bonner, Caroline;
Saponaro, Chiara

Publication type:

Article

Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1 alpha (HNF1A-MODY) carriers from the third decade of life onward.

Published in:

BMC Endocrine Disorders, 2012, v. 12, n. 1, p. 13, doi. 10.1186/1472-6823-12-13

By:

Bacon, Siobhan;
Peyh Kyithar, Ma;
Schmid, Jasmin;
Rizvi, Syed R.;
Bonner, Caroline;
Graf, Rolf;
Prehn, Jochen H. M.;
Byrne, Maria M.

Publication type:

Article

E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.

Published in:

2016

By:

Denechaud, Pierre-Damien;
Lopez-Mejia, Isabel C.;
Giralt, Albert;
Qiuwen Lai;
Blanchet, Emilie;
Delacuisine, Brigitte;
Nicolay, Brandon N.;
Dyson, Nicholas J.;
Bonner, Caroline;
Pattou, François;
Annicotte, Jean-Sebastien;
Fajas, Lluis;
Lai, Qiuwen;
Annicotte, Jean-Sébastien

Publication type:

journal article

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163046

By:

Plaisance, Valérie;
Brajkovic, Saška;
Tenenbaum, Mathie;
Favre, Dimitri;
Ezanno, Hélène;
Bonnefond, Amélie;
Bonner, Caroline;
Gmyr, Valéry;
Kerr-Conte, Julie;
Gauthier, Benoit R.;
Widmann, Christian;
Waeber, Gérard;
Pattou, François;
Froguel, Philippe;
Abderrahmani, Amar

Publication type:

Article

AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis.

Published in:

Journal of Cell Biology, 2010, v. 189, n. 1, p. 83, doi. 10.1083/jcb.200909166

By:

Concannon, Caoimhín G.;
Tuffy, Liam P.;
Weisová, Petronela;
Bonner, Helena P.;
Dávila, David;
Bonner, Caroline;
Devocelle, Marc C.;
Strasser, Andreas;
Ward, Manus W.;
Prehn, Jochen H. M.

Publication type:

Article

PSP/reg: a potent and enigmatic trophic factor, which is upregulated during the pathogenesis of diabetes.

Published in:

2015

By:

Bonner, Caroline

Publication type:

Editorial

The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45548-w

By:

Benichou, Emmanuel;
Seffou, Bolaji;
Topçu, Selin;
Renoult, Ophélie;
Lenoir, Véronique;
Planchais, Julien;
Bonner, Caroline;
Postic, Catherine;
Prip-Buus, Carina;
Pecqueur, Claire;
Guilmeau, Sandra;
Alves-Guerra, Marie-Clotilde;
Dentin, Renaud

Publication type:

Article

Correction: Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans.

Published in:

2025

By:

Wreven, Elise;
de Adana, María Soledad Ruiz;
Hardivillé, Stéphan;
Gmyr, Valery;
Kerr-Conte, Julie;
Chetboun, Mikael;
Pasquetti, Gianni;
Delalleau, Nathalie;
Thévenet, Julien;
Coddeville, Anaïs;
Herrera, María José Vallejo;
Hinden, Liad;
Espínola, Inmaculada Concepción Benavides;
Duro, Mireia Gómez;
Salido, Lourdes Sanchez;
Linares, Francisca;
Bermúdez-Silva, Francisco-Javier;
Tam, Joseph;
Bonner, Caroline;
Egan, Josephine M.

Publication type:

Correction Notice

Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans.

Published in:

Diabetologia, 2024, v. 67, n. 9, p. 1877, doi. 10.1007/s00125-024-06193-6

By:

Wreven, Elise;
Ruiz de Adana, María Soledad;
Hardivillé, Stéphan;
Gmyr, Valery;
Kerr-Conte, Julie;
Chetboun, Mikael;
Pasquetti, Gianni;
Delalleau, Nathalie;
Thévenet, Julien;
Coddeville, Anaïs;
Vallejo Herrera, María José;
Hinden, Liad;
Benavides Espínola, Inmaculada Concepción;
Gómez Duro, Mireia;
Sanchez Salido, Lourdes;
Linares, Francisca;
Bermúdez-Silva, Francisco-Javier;
Tam, Joseph;
Bonner, Caroline;
Egan, Josephine M.

Publication type:

Article

Where to for precision treatment of HNF1A-MODY?

Published in:

Diabetologia, 2022, v. 65, n. 11, p. 1825, doi. 10.1007/s00125-022-05696-4

By:

Bonner, Caroline;
Saponaro, Chiara

Publication type:

Article

Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.

Published in:

Apoptosis, 2011, v. 16, n. 11, p. 1128, doi. 10.1007/s10495-011-0641-x

By:

Farrelly, Angela;
Kilbride, Seán;
Bonner, Caroline;
Prehn, Jochen;
Byrne, Maria

Publication type:

Article

Primary Graft Function and 5Year Insulin Independence After Pancreas and Islet Transplantation for Type 1 Diabetes: A Retrospective Parallel Cohort Study.

Published in:

Transplant International, 2024, p. 1, doi. 10.3389/ti.2023.11950

By:

Chetboun, Mikael;
Masset, Christophe;
Maanaoui, Mehdi;
Defrance, Frédérique;
Gmyr, Valéry;
Raverdy, Violeta;
Hubert, Thomas;
Bonner, Caroline;
Supiot, Lisa;
Kerleau, Clarisse;
Blancho, Gilles;
Branchereau, Julien;
Karam, Georges;
Chelghaf, Ismaël;
Houzet, Aurélie;
Giral, Magali;
Garandeau, Claire;
Dantal, Jacques;
Mapihan, Kristell Le;
Jannin, Arnaud

Publication type:

Article

Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.

Published in:

Nature Medicine, 2015, v. 21, n. 5, p. 512, doi. 10.1038/nm.3828

By:

Bonner, Caroline;
Kerr-Conte, Julie;
Gmyr, Valéry;
Queniat, Gurvan;
Moerman, Ericka;
Thévenet, Julien;
Beaucamps, Cédric;
Delalleau, Nathalie;
Popescu, Iuliana;
Malaisse, Willy J;
Sener, Abdullah;
Deprez, Benoit;
Abderrahmani, Amar;
Staels, Bart;
Pattou, François

Publication type:

Article

Hypothalamic Neuropeptide 26RFa Acts as an Incretin to Regulate Glucose Homeostasis.

Published in:

Diabetes, 2015, v. 64, n. 8, p. 2805, doi. 10.2337/db14-1864

By:

Prévost, Gaëtan;
Jeandel, Lydie;
Arabo, Arnaud;
Coëffier, Moïse;
El Ouahli, Mariama;
Picot, Marie;
Alexandre, David;
Gobet, Françoise;
Leprince, Jérôme;
Berrahmoune, Hind;
Déchelotte, Pierre;
Malagon, Maria;
Bonner, Caroline;
Kerr-Conte, Julie;
Chigr, Fatiha;
Lefebvre, Hervé;
Anouar, Youssef;
Chartrel, Nicolas

Publication type:

Article

INS-1 Cells Undergoing Caspase-Dependent Apoptosis Enhance the Regenerative Capacity of Neighboring Cells.

Published in:

Diabetes, 2010, v. 59, n. 11, p. 2799, doi. 10.2337/db09-1478

By:

Bonner, Caroline;
Bacon, Siobhán;
Concannon, Caoimhín G.;
Rizvi, Syed R.;
Baquié, Mathurin;
Farrelly, Angela M.;
Kilbride, Seán M.;
Dussmann, Heiko;
Ward, Manus W.;
Boulanger, Chantal M.;
Wollheim, Claes B.;
Graf, Rolf;
Byrne, Maria M.;
Prehn, Jochen H. M.

Publication type:

Article

Role of AMPK/mTOR Signalling during Dominant-Negative Suppression of HNF-1 alpha Function in INS-1 Insulinoma Cells.

Published in:

Diabetes, 2007, v. 56, p. A444

By:

Farrelly, Angela M.;
Bonner, Caroline T.;
Prehn, Jochen H.;
Byrne, Maria M.

Publication type:

Article

Potent Downregulation of Bone Morphogenetic Protein 3 (BMP3) Gene Expression in INS-1 Cells Inducibly Expressing a MODY-3 Tcf-1/HNF1alpha Mutation.

Published in:

Diabetes, 2007, v. 56, p. A423

By:

Bonner, Caroline T.;
Koenig, Hans-Georg;
Farrelly, Angela M.;
Byrne, Maria M.;
Prehn, Jochen H.

Publication type:

Article

Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability.

Published in:

Journal of Neurochemistry, 2010, v. 114, n. 2, p. 606, doi. 10.1111/j.1471-4159.2010.06790.x

By:

Bonner, Helena P.;
Concannon, Caoimhín G.;
Bonner, Caroline;
Woods, Ina;
Ward, Manus W.;
Prehn, Jochen H. M.

Publication type:

Article

NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner.

Published in:

Journal of Neurochemistry, 2008, v. 105, n. 3, p. 891, doi. 10.1111/j.1471-4159.2007.05187.x

By:

Concannon, Caoimhín G.;
Ward, Manus W.;
Bonner, Helena P.;
Kuroki, Katsura;
Tuffy, Liam P.;
Bonner, Caroline T.;
Woods, Ina;
Engel, Tobias;
Henshall, David C.;
Prehn, Jochen H. M.

Publication type:

Article

Induction of transcription factor CEBP homology protein mediates hypoglycaemia-induced necrotic cell death in human neuroblastoma cells.

Published in:

Journal of Neurochemistry, 2006, v. 99, n. 3, p. 952, doi. 10.1111/j.1471-4159.2006.04135.x

By:

Kögel, Donat;
Svensson, Birte;
Copanaki, Ekaterini;
Anguissola, Sergio;
Bonner, Caroline;
Thurow, Nadia;
Gudorf, Daniel;
Hetschko, Holger;
Müller, Thorsten;
Peters, Marion;
König, Hans-Georg;
Prehn, Jochen H. M.

Publication type:

Article

THE FIONA STANLEY HOSPITAL 'MAKING THE CHANGES' MATERNITY SERVICE STEERING GROUP: CONSUMERS, COMMUNITY MEMBERS AND CLINICIANS COLLABORATING FOR CARE QUALITY.

Published in:

Australian Midwifery News, 2025, v. 40, n. 1, p. 38

By:

Bayes, Sara;
Buchanan, Kate;
Coulson-Bonner, Caroline;
Davies, Rowena;
Ekin, Kylie;
Fisher, Peta;
Graham, Leanne;
O'Meagher, Amy;
Sarney, Pallas;
Snelgar, Emma

Publication type:

Article

O-GlcNacylation Links TxNIP to Inflammasome Activation in Pancreatic β Cells.

Published in:

Frontiers in Endocrinology, 2019, p. N.PAG, doi. 10.3389/fendo.2019.00291

By:

Filhoulaud, Gaelle;
Benhamed, Fadila;
Pagesy, Patrick;
Bonner, Caroline;
Fardini, Yann;
Ilias, Anissa;
Movassat, Jamileh;
Burnol, Anne-Françoise;
Guilmeau, Sandra;
Kerr-Conte, Julie;
Pattou, François;
Issad, Tarik;
Postic, Catherine

Publication type:

Article

Effects of hepatocyte nuclear factor-1A and -4A on pancreatic stone protein/regenerating protein and C-reactive protein gene expression: implications for maturity-onset diabetes of the young.

Published in:

Journal of Translational Medicine, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1479-5876-11-156

By:

Kyithar, Ma P.;
Bonner, Caroline;
Bacon, Siobhan;
Kilbride, Seán M.;
Schmid, Jasmin;
Graf, Rolf;
Prehn, Jochen H. M.;
Byrne, Maria M.

Publication type:

Article

Effects of hepatocyte nuclear factor-1A and -4A on pancreatic stone protein/regenerating protein and C-reactive protein gene expression: implications for maturity-onset diabetes of the young.

Published in:

2013

By:

Kyithar, Ma P;
Bonner, Caroline;
Bacon, Siobhan;
Kilbride, Seán M;
Schmid, Jasmin;
Graf, Rolf;
Prehn, Jochen H M;
Byrne, Maria M

Publication type:

journal article

2056-P: In Vivo Human Islet Compensation and Dysfunction to Diet-Induced Obesity: A Phase 0 Preclinical Model.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2056-P

By:

KERR-CONTE, JULIE A.;
THEVENET, JULIEN;
PASQUETTI, GIANNI;
PETIT, PAULINE;
CLABAUT, CLARA;
GMYR, VALERY;
BONNER, CAROLINE;
GARGANI, SOFIA;
PATTOU, FRANCOIS

Publication type:

Article

1900-P: HNF1A Deficiency Leads to Perturbed Glucagon Secretion in Humans.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1900-P

By:

SAPONARO, CHIARA;
ACOSTA-MONTALVO, ANA;
ANGUELOVA, LIA;
THEVENET, JULIEN;
CHIRAL, MAGALI;
PASQUETTI, GIANNI;
PIRON, ANTHONY;
CNOP, MIRIAM;
GMYR, VALERY;
PREHN, JOCHEN;
KERR-CONTE, JULIE A.;
PATTOU, FRANCOIS;
PONTOGLIO, MARCO;
OWEN, KATHARINE R.;
SPILIOTIS, IOANNIS;
BONNER, CAROLINE

Publication type:

Article

Interindividual Heterogeneity of SGLT2 Expression and Function in Human Pancreatic Islets.

Published in:

Diabetes, 2020, v. 69, n. 5, p. 902, doi. 10.2337/db19-0888

By:

Saponaro, Chiara;
Mühlemann, Markus;
Acosta-Montalvo, Ana;
Piron, Anthony;
Gmyr, Valery;
Delalleau, Nathalie;
Moerman, Ericka;
Thévenet, Julien;
Pasquetti, Gianni;
Coddeville, Anais;
Cnop, Miriam;
Kerr-Conte, Julie;
Staels, Bart;
Pattou, François;
Bonner, Caroline

Publication type:

Article